Metallic ureteral stents in malignant ureteral obstruction: clinical factors predicting stent failure.

Abstract:

PURPOSE:To provide clinical outcomes of the Resonance metallic ureteral stent in patients with malignant ureteral obstruction, as well as clinical factors predicting stent failure. METHODS:Cancer patients who have received Resonance stents from July 2009 to March 2012 for ureteral obstruction were included for chart review. Stent failure was detected by clinical symptoms, image studies, and renal function tests. Survival analysis for stent duration was used to estimate patency rate and factors predicting stent failure. RESULTS:A total of 117 stents were inserted successfully into 94 ureteral units in 79 patients. There were no major complications. These stents underwent survival analysis and proportional hazard regression. The median duration for the stents was 5.77 months. In multivariate analysis, age (P=0.043), preoperative serum creatinine level (P=0.0174), and cancer type (P=0.0494) were significant factors associated with stent failure. Cancer treatment before and after stent insertion had no effect on stent duration. CONCLUSIONS:Resonance stents are effective and safe in relieving malignant ureteral obstructions. Old age and high serum creatinine level are predictors for stent failure. Stents in patients with lower gastrointestinal cancers have longer functional duration.

journal_name

J Endourol

journal_title

Journal of endourology

authors

Chow PM,Hsu JS,Huang CY,Wang SM,Lee YJ,Huang KH,Yu HJ,Pu YS,Liang PC

doi

10.1089/end.2013.0792

subject

Has Abstract

pub_date

2014-06-01 00:00:00

pages

729-34

issue

6

eissn

0892-7790

issn

1557-900X

journal_volume

28

pub_type

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