Abstract：
PURPOSE:The composition and mechanical properties of abdominal aortic aneurysms (AAAs) were studied. METHODS:Stereologic study was used to measure volume fractions of the components of the aortic wall. Histochemical methods with picrosirus red and safranin O were developed to differentiate collagen from ground substance because they are difficult to distinguish from each other on histologic sections. Uniaxial tensile stress tests were carried out on a tensile-testing machine, and a stress-strain curve was plotted for each sample to study the mechanical properties of AAAs. The curves were fitted exponentially so sigma = aeb epsilon, where sigma is stress, epsilon is strain, and a and b are parameters. RESULTS:In aneurysms (n = 8) the volume fraction of elastin was decreased from 22.7% +/- 5.7% to 2.4% +/- 2.2%, and the volume fraction of smooth muscle cells was decreased from 22.6% +/- 5.5% to 2.2% +/- 2.0%, whereas the volume fraction of collagen and ground substance combined was increased from 54.8% +/- 4.5% to 95.6% +/- 2.5% compared with nonaneurysmal aortas (n = 8). There was no significant difference (p > 0.05) in the ratio of collagen to ground substance (2.1 +/- 0.5 vs 2.0 +/- 0.4) between AAAs and nonaneurysmal aortas. The elastic diagrams showed that AAAs (n = 7) are less distensible and stiffer than nonaneurysmal aortas (n = 5). Parameter a was unchanged (p > 0.5), but parameter b was significantly greater (p < 0.002) for aneurysmal aortas. CONCLUSIONS:Both the composition and mechanical properties of AAAs are different from those of nonaneurysmal aortas. The aneurysms were stiffer, and the volume fractions of collagen and ground substance were increased, whereas the volume fractions of elastin and muscle were decreased in aneurysms.
journal_name
J Vasc Surgjournal_title
Journal of vascular surgeryauthors
He CM,Roach MRdoi
10.1016/0741-5214(94)90169-4subject
Has Abstractpub_date
1994-07-01 00:00:00pages
6-13issue
1eissn
0741-5214issn
1097-6809pii
0741-5214(94)90169-4journal_volume
20pub_type
杂志文章abstract：OBJECTIVES:Critical limb ischemia (CLI) patients who are unsuitable for intervention face the dire prospect of primary amputation. Sequential compression biomechanical device (SCBD) therapy provides a limb salvage option for these patients. This study assessed the outcome of SCBD in severe CLI patients who otherwise wo...
journal_title：Journal of vascular surgery
pub_type： 杂志文章
doi：10.1016/j.jvs.2011.02.057
更新日期：2011-08-01 00:00:00
abstract：PURPOSE:Recently, we have reported that lipid peroxidation specific to oxygen free radical-mediated injury increased immediately after reperfusion of human liver allografts. However, in the human liver transplantation setting it was impossible to disassociate the contributions to lipid peroxidation caused by the warm a...
journal_title：Journal of vascular surgery
pub_type： 杂志文章
doi：10.1016/s0741-5214(94)70074-5
更新日期：1994-03-01 00:00:00
abstract：:We performed radiofrequency ablation to treat a symptomatic facial venous malformation of a 24-year-old woman under ultrasound scan-guidance. The 20.25-cm sized original facial venous malformation in her right cheek markedly reduced without any scar formation and was grossly not visible after 1 month of the procedure....
journal_title：Journal of vascular surgery
pub_type： 杂志文章
doi：10.1016/j.jvs.2009.03.047
更新日期：2009-08-01 00:00:00
abstract：BACKGROUND:Carotid artery stenting (CAS) leads to frequent embolic brain lesions; their source has not been clearly identified yet. In order to investigate this phenomenon, we have evaluated embolic brain lesions (BL) after CAS and correlated them with aortic arch (AA) characteristics. METHODS:The AAs of 59 patients u...
journal_title：Journal of vascular surgery
pub_type： 杂志文章
doi：10.1016/j.jvs.2008.08.014
更新日期：2009-01-01 00:00:00
abstract：:We report the case of a 78-year-old man with coronary artery disease, chronic obstructive pulmonary disease, and chronic renal insufficiency with an enlarging 6.7-cm infrarenal abdominal aortic aneurysm. He also had a 4-cm right common iliac artery aneurysm, and right external iliac artery occlusion. The patient had a...
journal_title：Journal of vascular surgery
pub_type： 杂志文章
doi：10.1016/j.jvs.2013.05.105
更新日期：2014-06-01 00:00:00
abstract：OBJECTIVE:Abdominal aortic aneurysms (AAAs) are associated with generalized arterial dilation, torturosity, and altered matrix composition, which suggests a generalized systemic weakness throughout the entire vasculature. The aim of this study was to determine whether this phenomenon was present in the venous tissue of...
journal_title：Journal of vascular surgery
pub_type： 杂志文章
doi：10.1067/mva.2002.122877
更新日期：2002-05-01 00:00:00
abstract：OBJECTIVE:Visceral artery aneurysms (VAAs) are rare but often repaired because of dire consequences of rupture. This is a population-based evaluation of chronologic trends in management, risk factors, and outcomes of endovascular and open therapy. METHODS:The 2003 to 2013 Agency for Healthcare Research and Quality (AH...
journal_title：Journal of vascular surgery
pub_type： 杂志文章
doi：10.1016/j.jvs.2017.02.036
更新日期：2017-07-01 00:00:00
abstract：:We report the vascular surgical strategies and results in 13 patients with heparin-associated thrombocytopenia and describe useful in vitro techniques for the evaluation of anticoagulant therapy. Thirteen of 40 patients with heparin-associated thrombocytopenia had 18 cardiovascular procedures done to save life or limb...
journal_title：Journal of vascular surgery
pub_type： 杂志文章
doi：
更新日期：1988-10-01 00:00:00
abstract：PURPOSE:The purpose of this study was to evaluate the long-term safety and efficacy of the titanium Greenfield filter-modified hook for prevention of pulmonary embolism. METHODS:We conducted a prospective study in 173 patients from four institutions who underwent clinical examination, abdominal radiography, and duplex...
journal_title：Journal of vascular surgery
pub_type： 杂志文章
doi：10.1016/0741-5214(94)90146-5
更新日期：1994-09-01 00:00:00
abstract：PURPOSE:Human vascular prostheses develop a pseudointima that after time is devoid of a complete endothelial lining. The composition of this pseudointima consists of both cellular and noncellular components such as coagulation proteins and extracellular matrix proteins. Of these extracellular molecules, type V collagen...
journal_title：Journal of vascular surgery
pub_type： 杂志文章
doi：10.1067/mva.1993.40730
更新日期：1993-04-01 00:00:00
abstract：OBJECTIVE:Our study aimed to perform a meta-analysis based on current evidence to investigate the efficacy of different debulking devices in the treatment of femoropopliteal in-stent restenosis (FP-ISR). METHODS:We systematically searched for articles reporting treatment of FP-ISR patients in the MEDLINE, Embase, and ...
journal_title：Journal of vascular surgery
pub_type： 杂志文章,meta分析
doi：10.1016/j.jvs.2019.11.058
更新日期：2020-07-01 00:00:00
abstract：OBJECTIVE:Prior studies have suggested improved wound complication rates but decreased primary patency in lower extremity bypasses performed with endoscopic vein harvest (EVH) vs open vein harvest (OVH). We hypothesize that the inferior patency reflects the initial learning curve for EVH and that improved patency can b...
journal_title：Journal of vascular surgery
pub_type： 杂志文章
doi：10.1016/j.jvs.2019.02.043
更新日期：2019-11-01 00:00:00
abstract：BACKGROUND:The prevailing evidence calls for using chimney/snorkel endovascular repair (ch-EVAR) with one or two chimney grafts. No studies up to now focus on its applicability and results for the treatment of suprarenal aortic pathologies (SRAP). Hence, we evaluated the clinical and radiologic results of ch-EVAR treat...
journal_title：Journal of vascular surgery
pub_type： 杂志文章,多中心研究
doi：10.1016/j.jvs.2019.08.228
更新日期：2020-05-01 00:00:00
abstract：BACKGROUND:International guidelines recommend carotid revascularization within 14 days for patients with a symptomatic transient ischemic attack (TIA) or stroke event. However, significant delays in care persist, with only 9% of outpatients and 36% of inpatients in Ontario meeting this target. The study objective was t...
journal_title：Journal of vascular surgery
pub_type： 杂志文章
doi：10.1016/j.jvs.2020.02.024
更新日期：2020-11-01 00:00:00
abstract：PURPOSE:Carotid endarterectomy (CEA) has proven to be effective in the prevention of stroke in patients with significant internal carotid artery (ICA) stenosis. However, whether increased cerebral blood flow after CEA improves the cerebral metabolism in patients with asymptomatic ICA flow lesions is unknown. Localized ...
journal_title：Journal of vascular surgery
pub_type： 杂志文章
doi：10.1067/mva.2002.126555
更新日期：2002-09-01 00:00:00
abstract：OBJECTIVE:The aim of this study was to identify whether revascularization by percutaneous transluminal angioplasty (PTA) for patients with intermittent claudication improved measures of functional performance including balance. METHODS:A prospective observational study was performed at a single tertiary vascular cente...
journal_title：Journal of vascular surgery
pub_type： 杂志文章
doi：10.1016/j.jvs.2013.05.106
更新日期：2013-12-01 00:00:00
abstract：:Endovascular techniques with coil embolization have been used in certain visceral aneurysm cases, often resulting in sacrifice of the involved visceral vessel and end-organ thrombosis. We describe two cases in which stent grafts were used to treat these aneurysms, allowing preservation of visceral artery and end-organ...
journal_title：Journal of vascular surgery
pub_type： 杂志文章
doi：10.1067/mva.2002.129645
更新日期：2002-12-01 00:00:00
abstract：BACKGROUND:Treatment of chronic venous insufficiency (CVI) has largely focused on reflux. Minimally-invasive techniques to address superficial and perforator reflux have evolved, but correction of deep reflux continues to be challenging. The advent of intravascular ultrasound (IVUS) scan and minimally invasive venous s...
journal_title：Journal of vascular surgery
pub_type： 杂志文章
doi：10.1016/j.jvs.2009.08.032
更新日期：2010-02-01 00:00:00
abstract：OBJECTIVE:This study assessed whether the duplex ultrasound (DUS)-derived gray-scale median (GSM) of the most six distal portion of the occluded femoral-popliteal arterial segment can predict success of lumen re-entry for subintimal angioplasty. METHODS:During the last 3 years, 108 patients (62% men) with a mean age o...
journal_title：Journal of vascular surgery
pub_type： 杂志文章
doi：10.1016/j.jvs.2007.09.039
更新日期：2008-01-01 00:00:00
abstract：OBJECTIVE:To achieve an optimal sealing zone during endovascular aneurysm repair, the intended positioning of the proximal end of the endograft fabric should be as close as possible to the most caudal edge of the renal arteries. Some endografts exhibit a small offset between the radiopaque markers and the proximal fabr...
journal_title：Journal of vascular surgery
pub_type： 杂志文章
doi：10.1016/j.jvs.2017.05.092
更新日期：2018-05-01 00:00:00
abstract：:Ninety-two patients underwent surgical treatment for 59 prosthetic graft infections and 33 secondary aortoenteric fistulas. Definitive treatment was accomplished with a low perioperative mortality rate (14%). Long-term follow-up confirmed that most patients were cured of their infection or fistula, and 88% of the pati...
journal_title：Journal of vascular surgery
pub_type： 杂志文章
doi：
更新日期：1984-01-01 00:00:00
abstract：BACKGROUND:Spinal cord ischemia is a rare complication after open surgical repair for ruptured abdominal aortic aneurysms (rAAA). The use of emergency endovascular aortic aneurysm repair (eEVAR) is increasing, and paraplegia has been observed in a few patients. The objective of this study was to assess the incidence an...
journal_title：Journal of vascular surgery
pub_type： 杂志文章,多中心研究
doi：10.1016/j.jvs.2005.06.023
更新日期：2005-10-01 00:00:00
abstract：PURPOSE:Intraoperative duplex scanning (IDS) after carotid endarterectomy (CEA) has been shown to reliably identify major defects either by significant changes in peak systolic velocities or by B-mode imaging. To evaluate whether IDS could also predict postoperative strokes in technically flawless CEAs, we analyzed sev...
journal_title：Journal of vascular surgery
pub_type： 杂志文章
doi：10.1067/mva.2002.120044
更新日期：2002-03-01 00:00:00
abstract：:We report the case of a 40-year-old woman with posttraumatic arteriovenous fistula of the right radialis indicis artery. The patient was admitted because a pulsatile lesion appeared on her hand after blunt trauma. Liquid sclerotherapy using 3% polidocanol in combination with distal protection using the rubber band tec...
journal_title：Journal of vascular surgery
pub_type： 杂志文章
doi：10.1016/j.jvs.2010.05.092
更新日期：2010-11-01 00:00:00
abstract：OBJECTIVE:Varicose vein recurrence after surgery occurs in up to 60% of patients. A variety of technical factors have been implicated, but biological factors such as neovascularization have more recently been proposed. The objective of this study was to characterize the relative contribution of technical and biological...
journal_title：Journal of vascular surgery
pub_type： 杂志文章
doi：10.1016/j.jvs.2006.08.017
更新日期：2006-12-01 00:00:00
abstract：PURPOSE:This study was conducted to assess the efficacy of antibiotic-loaded polymethylmethacrylate (PMMA) beads in the management of lower extremity extracavitary prosthetic arterial graft infection. METHODS:This was a retrospective review of 34 patients treated for vascular surgical site (VSS) infections involving 3...
journal_title：Journal of vascular surgery
pub_type： 杂志文章
doi：10.1016/j.jvs.2006.05.056
更新日期：2006-10-01 00:00:00
abstract：OBJECTIVES:Vascular surgery training has evolved from a single clinical year after general surgery training to a multi-year training program to encompass such entities as noninvasive vascular laboratory, office-based procedures, and endovascular techniques. Simultaneously, members of the vascular surgery community have...
journal_title：Journal of vascular surgery
pub_type： 杂志文章
doi：10.1016/j.jvs.2009.10.109
更新日期：2010-03-01 00:00:00
abstract：PURPOSE:Reconstruction techniques tailored to operative findings were applied to 466 consecutive carotid endarterectomies (CEA) performed on 408 patients over 5 years. The choice of reconstructive technique was based on the extent of the arteriotomy incision required to obtain a complete internal CEA endpoint, the abil...
journal_title：Journal of vascular surgery
pub_type： 杂志文章
doi：10.1016/0741-5214(93)90018-h
更新日期：1993-01-01 00:00:00
abstract：PURPOSE:Post-carotid endarterectomy, thrombosis, and intimal hyperplasia may be decreased by the inhibition of platelet adhesion and activation. In this study, a novel agent, saratin, was used to inhibit platelet-to-collagen adhesion in a rat carotid endarterectomy model. Saratin is a recombinant protein isolated from ...
journal_title：Journal of vascular surgery
pub_type： 杂志文章
doi：10.1067/mva.2001.116801
更新日期：2001-10-01 00:00:00
abstract：PURPOSE:This report describes our experience with endovascular stented graft repair of abdominal aortic aneurysms and other arterial lesions. METHODS:Between September 1990 and April 1994, 57 patients were treated with endovascular stented grafts (50 with abdominal aortic aneurysms or iliac aneurysms; five with trauma...
journal_title：Journal of vascular surgery
pub_type： 杂志文章
doi：10.1016/s0741-5214(95)70186-9
更新日期：1995-04-01 00:00:00
