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Endovascular treatment for intermittent claudication in patients with peripheral arterial disease: a systematic review.

Abstract：

BACKGROUND:We performed a systematic review and meta-analysis to examine whether patients with intermittent claudication can benefit from endovascular treatment (EVT). METHODS:A prespecified search strategy was used to identify relevant studies in the MEDLINE, Embase, and Cochrane databases. A total of 10 different randomized, controlled trials were reviewed. Random effects meta-analysis was performed between the EVT plus conservative treatment (CT) group and the CT group alone. Also, random effects meta-analysis was performed between the EVT group and the supervised exercise therapy (SET) group. RESULTS:The independent effect of EVT could directly improve the ankle-brachial index (ABI) and walking performance over the short term, but not over the long term. Moreover, compared to SET, EVT had the superiority in improving the ABI, while SET could improve walking performance more efficiently. CONCLUSIONS:Patients with intermittent claudication may benefit from endovascular treatment over the short term (within 12 months), with improvements in ABI, intermittent claudication distance, and maximum walking distance. However, considering improvements on walking performance (especially over the long term), SET is recommended.

journal_name

Ann Vasc Surg

journal_title

Annals of vascular surgery

authors

Liu J,Wu Y,Li Z,Li W,Wang S

doi

10.1016/j.avsg.2013.05.022

subject

Has Abstract

pub_date

2014-05-01 00:00:00

pages

977-82

issue

4

eissn

0890-5096

issn

1615-5947

pii

S0890-5096(13)00675-4

journal_volume

28

pub_type

杂志文章,meta分析,评审

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