Abstract:
:Balloon angioplasty produces a mechanically induced injury to the blood vessel wall. Heat shock protein 70 (HSP70) is a molecular chaperone whose expression can be induced by chemical or thermal stress. Thus, we hypothesized that the mechanical injury associated with balloon angioplasty would lead to increases in the expression of HSP70 in vascular smooth muscle. Segments of popliteal and trifurcation vessels from above-the-knee amputations were subject to transluminal balloon angioplasty, excised, and placed in organ cultures. Neighboring vessel that was not subjected to balloon angioplasty served as controls. Some vessels were treated with sodium arsenite (positive control, known to induce HSP70 expression). The vessels were homogenized and the proteins were separated by gel electrophoresis and transferred to Immobilon. Western blots with an antibody specific for the inducible form of HSP70 were analyzed by densitometry. Our results showed that HSP70 expression can be induced by the mechanical injury associated with balloon angioplasty in human atherosclerotic vessels.
journal_name
Ann Vasc Surgjournal_title
Annals of vascular surgeryauthors
Kirby LB,Mondy JS,Brophy CMdoi
10.1007/s100169900286subject
Has Abstractpub_date
1999-09-01 00:00:00pages
475-9issue
5eissn
0890-5096issn
1615-5947pii
S0890-5096(06)61798-6journal_volume
13pub_type
杂志文章abstract:BACKGROUND:The aim of this study was to detail our experience in the management of skin necrosis/ulceration over hemodialysis vascular accesses. METHODS:We collected demographics and operative data about patients undergoing surgery for skin necrosis over native or prosthetic vascular accesses. The different procedural...
journal_title:Annals of vascular surgery
pub_type: 杂志文章
doi:10.1016/j.avsg.2020.11.030
更新日期:2020-12-28 00:00:00
abstract::Ruptured abdominal aortic aneurysm (AAA) remains a common and highly lethal problem. This study evaluates the morbidity and mortality rates and aims to identify which clinical variables could predict the outcome. We reviewed the records of 112 patients (97 men and 15 women) operated on for ruptured infrarenal AAA with...
journal_title:Annals of vascular surgery
pub_type: 杂志文章
doi:10.1007/BF02018826
更新日期:1995-11-01 00:00:00
abstract:BACKGROUND:The aim of this study is to compare 2 groups of patients treated for great saphenous vein (GSV) reflux with open surgical saphenofemoral ligation (SFL) and endovenous laser ablation (EVLA). METHODS:Consecutive patients with primary unilateral GSV reflux undergoing EVLA treatment since 2014 were enrolled, an...
journal_title:Annals of vascular surgery
pub_type: 杂志文章
doi:10.1016/j.avsg.2018.11.029
更新日期:2019-07-01 00:00:00
abstract:BACKGROUND:Blunt thoracic aortic injuries (BTAIs) are rare but life threatening. Most BTAI are caused by high-energy trauma. Among children with blunt trauma, the incidence of BTAI is below 1 percent. The present case deals with covered thoracic aortic rupture of a 15-year-old boy. Emphasizing the value and the difficu...
journal_title:Annals of vascular surgery
pub_type: 杂志文章
doi:10.1016/j.avsg.2015.10.040
更新日期:2016-05-01 00:00:00
abstract:BACKGROUND:Takayasu arteritis (TA) is a rare, systemic, inflammatory vasculitis of granulomatous nature, and still of unknown etiology. It mainly involves the aorta and its major branches and is more commonly seen in women of childbearing age and Asians. TA leads to stenosis, occlusion, or aneurysmal degeneration of la...
journal_title:Annals of vascular surgery
pub_type: 杂志文章,评审
doi:10.1016/j.avsg.2016.02.011
更新日期:2016-08-01 00:00:00
abstract:BACKGROUND:Surgical bypass as treatment for chronic mesenteric ischemia (CMI) is performed to alleviate symptoms of weight loss and postprandial pain and to prevent catastrophic intestinal necrosis. Among the studies that report outcomes for mesenteric bypass, few focus on the type of conduit. The purpose of this study...
journal_title:Annals of vascular surgery
pub_type: 杂志文章,多中心研究
doi:10.1016/j.avsg.2011.11.006
更新日期:2012-05-01 00:00:00
abstract:BACKGROUND:In this study we analyzed embolization and stent-graft results. METHODS:Demographics, indications, procedures, and outcomes of patients treated with embolization or stent grafting for late postoperative bleeding after major abdominal surgery were retrospectively recorded. Outcomes were analyzed on an intent...
journal_title:Annals of vascular surgery
pub_type: 杂志文章
doi:10.1016/j.avsg.2012.10.024
更新日期:2013-11-01 00:00:00
abstract:BACKGROUND:Infection of a renal artery stent and pseudoaneurysm is extremely uncommon, with four reports in the literature. We present a fifth case and the complex management resulting in kidney salvage. METHODS AND RESULTS:A 56-year-old female underwent right renal artery stenting for hypertension. Postoperatively, s...
journal_title:Annals of vascular surgery
pub_type: 杂志文章
doi:10.1016/j.avsg.2009.06.018
更新日期:2010-01-01 00:00:00
abstract:BACKGROUND:Ligation and division of the saphenofemoral junction (L/D SFJ) can protect against the danger of venous thromboembolism (VTE) associated with greater saphenous vein (GSV) radiofrequency ablation (RFA). Although this procedure is regarded as clean from an infection standpoint, surgical site infection (SSI) ca...
journal_title:Annals of vascular surgery
pub_type: 杂志文章
doi:10.1016/j.avsg.2011.10.013
更新日期:2012-07-01 00:00:00
abstract::Forty consecutive patients were admitted alive to the operating theater with ruptured infrarenal aoritc aneurysms in a 3-year period and were assessed preoperatively with two scoring systems: the POSSUM (physiological and operative severity score for the enumeration of mortality) and the APACHE II (acute physiologic a...
journal_title:Annals of vascular surgery
pub_type: 杂志文章
doi:10.1007/s100169900026
更新日期:1997-03-01 00:00:00
abstract::Use of pedal bypass can salvage limbs of patients with critical ischemia. The aim of this study was to evaluate the results of surgical revascularization of pedal arteries in diabetic patients and to assess the impact of diabetes on long-term outcome. We performed a retrospective analysis of all consecutive pedal bypa...
journal_title:Annals of vascular surgery
pub_type: 杂志文章
doi:10.1007/s100169910114
更新日期:2000-11-01 00:00:00
abstract::Elective repair of abdominal aortic aneurysms (AAA) in the elderly has conventionally been associated with higher mortality rates than in younger patients, although some authors do not agree with this view. The aim of this study is to look into current results of surgical treatment in elderly patients with nonruptured...
journal_title:Annals of vascular surgery
pub_type: 杂志文章,多中心研究
doi:10.1007/s100160010082
更新日期:2001-05-01 00:00:00
abstract::Exposure of the distal internal carotid artery (ICA) above the level of the second cervical vertebra can be difficult and often require maneuvers such as division of the digastric muscle or mandibular subluxation. These techniques increase exposure but may not provide adequate access. We report a series of eight cases...
journal_title:Annals of vascular surgery
pub_type: 杂志文章
doi:10.1007/s100160010010
更新日期:2001-01-01 00:00:00
abstract:BACKGROUND:IVCFs are usually placed under fluoroscopic guidance in dedicated angiography suites. Bedside placement of inferior vena cava filters (IVCF) is possible in patients not suitable for transportation, but data regarding their use are limited. The objective of this study is to compare utilization, procedural out...
journal_title:Annals of vascular surgery
pub_type: 杂志文章
doi:10.1016/j.avsg.2016.06.013
更新日期:2017-02-01 00:00:00
abstract::The purpose of this study is to describe the advantages and value of an endovascular suite in the operating room from a vascular surgeon's perspective. All endovascular procedures were performed in a specially equipped operating room by vascular surgeons using digital fluoroscopic imaging equipment. Between January 1,...
journal_title:Annals of vascular surgery
pub_type: 杂志文章
doi:10.1007/s100169900157
更新日期:1998-05-01 00:00:00
abstract:BACKGROUND:Dynamic compliance (Cd) of the adult thoracic ascending and arch aorta has had limited in vivo evaluation in patients with aortic disease. This study evaluates aortic compliance using intravascular ultrasound (IVUS) across a range of thoracic aortic diseases. METHODS:Seventy-nine patients undergoing thoraci...
journal_title:Annals of vascular surgery
pub_type: 杂志文章
doi:10.1016/j.avsg.2018.12.060
更新日期:2019-05-01 00:00:00
abstract::The aim of this retrospective study was to substantiate our results of lower limb revascularizations from the descending thoracic aorta. From November 1984 to November 1994, we used bypass grafting from the descending thoracic aorta to revascularize 69 lower limbs in 36 patients, 34 men and 2 women, whose mean age was...
journal_title:Annals of vascular surgery
pub_type: 杂志文章
doi:10.1007/s100169910105
更新日期:2000-11-01 00:00:00
abstract::Infected or mycotic aneurysms (MAs) of the aorta and adjacent arteries are rare and difficult to treat. We report a unique case of a Salmonella serotype enteritidis-induced rapidly expanding aortic and iliac pseudoaneurysm during preoperative workup. Based on the presented case, we postulate that the agressive nature ...
journal_title:Annals of vascular surgery
pub_type: 杂志文章,评审
doi:10.1016/j.avsg.2017.05.034
更新日期:2017-10-01 00:00:00
abstract::Most physicians are aware of the important role that platelets play in thrombus formation. The mechanisms that regulate platelet function are now understood at the molecular level. The same biologic processes that control platelet participation in the hemostatic process also allow platelets to interact with the vessel...
journal_title:Annals of vascular surgery
pub_type: 杂志文章,评审
doi:10.1007/BF02001017
更新日期:1993-03-01 00:00:00
abstract::We report a rare case of primary aortoduodenal fistula (ADF) secondary to a Coxiella burnetii (Q fever) infection in a patient with an abdominal aortic aneurysm. A review of the available literature on the vascular complications of Q fever is presented. Q fever should be suspected in vascular patients with close anima...
journal_title:Annals of vascular surgery
pub_type: 杂志文章
doi:10.1007/s100169910046
更新日期:2000-05-01 00:00:00
abstract::Intimal sarcoma is a rare and aggressive vascular pathology. The literature describes about 140 cases. Because of late diagnosis, the median survival time is only a few months. Presentations vary from the localization. The most common symptoms are intravascular obstruction or embolization. Diagnosis is difficult and v...
journal_title:Annals of vascular surgery
pub_type: 杂志文章
doi:10.1016/j.avsg.2014.09.022
更新日期:2015-02-01 00:00:00
abstract::The aims of this study were to determine whether National Kidney Foundation (NKF) guidelines for native arteriovenous fistula (AVF) creation (at least 50% of all new end-stage renal disease [ESRD] patients and 40% of prevalent hemodialysis patients) could be met in an underserved population who presented in late stage...
journal_title:Annals of vascular surgery
pub_type: 杂志文章
doi:10.1016/j.avsg.2007.10.004
更新日期:2008-01-01 00:00:00
abstract::Despite the improvement in endovascular techniques, one aspect of aneurysmal disease that continues to be challenging is the management of aortoiliac aneurysms. Sacrificing the hypogastric artery (HGA) for effective treatment is not without sequelae, which may include buttocks claudication, colonic ischemia, spinal co...
journal_title:Annals of vascular surgery
pub_type: 杂志文章,评审
doi:10.1016/j.avsg.2014.10.019
更新日期:2015-02-01 00:00:00
abstract::Patients with severely diseased or occluded infrageniculate arteries, limited runoff, and tissue loss may often present for primary amputation. In this study, we review our experience with plantar artery revascularization when no other bypass options are feasible. All patients requiring infrainguinal bypass to the pla...
journal_title:Annals of vascular surgery
pub_type: 杂志文章
doi:10.1007/s100160010006
更新日期:2001-01-01 00:00:00
abstract:BACKGROUND:The natural history of penetrating aortic ulcer (PAU) has been variably described and clear guidelines are lacking. We reviewed our experience with PAUs in a tertiary referral center. METHODS:Imaging reports from January 2010 to December 2017 were retrospectively searched for the diagnosis of "penetrating a...
journal_title:Annals of vascular surgery
pub_type: 杂志文章
doi:10.1016/j.avsg.2018.12.062
更新日期:2019-05-01 00:00:00
abstract::This study is based on a unique registry of 632 patients who underwent great saphenous vein (GSV) stripping and liberal use of subfascial endoscopic perforator vein surgery (SEPS) for minimal to severe lower limb venous insufficiency. Clinical examinations and color-coded duplex scanning were performed on a randomly s...
journal_title:Annals of vascular surgery
pub_type: 杂志文章
doi:10.1007/s10016-003-0032-z
更新日期:2003-09-01 00:00:00
abstract::A 72-year-old man with suprarenal aneurysm and 2 large penetrating ulcers (PAUs) in the descending aorta was referred for endovascular treatment. To avoid long-segment aortic coverage and the attendant risk of spinal ischemia, combination of 2 different stent technologies was used. A multilayer flow modulator was impl...
journal_title:Annals of vascular surgery
pub_type:
doi:10.1016/j.avsg.2019.05.042
更新日期:2019-11-01 00:00:00
abstract:BACKGROUND:Axillary artery aneurysms are rare conditions, and their causes are various. They can determine severe complications, so the treatment is extremely important. METHODS:We report the case of a young man affected by a saccular axillary artery aneurysm associated with intramuscular arteriovenous malformation, w...
journal_title:Annals of vascular surgery
pub_type:
doi:10.1016/j.avsg.2020.09.053
更新日期:2020-11-04 00:00:00
abstract::The purpose of this study was to investigate the presence of, and to identify factors associated with carotid atherosclerosis in patients, previously operated on for lower extremity ischemia before the age of 50. Forty-eight patients were compared to sex- and age-matched controls. All subjects were examined with duple...
journal_title:Annals of vascular surgery
pub_type: 杂志文章
doi:10.1007/s100169900180
更新日期:1998-09-01 00:00:00
abstract:BACKGROUND:Many studies confirmed the role of early carotid endarterectomy (CEA) to prevent recurrent stroke or transient ischemic attack; however, the mid-long-term neurological benefit is still not completely investigated. The purpose of the study was to evaluate the role of early CEA on the perioperative and postope...
journal_title:Annals of vascular surgery
pub_type: 杂志文章
doi:10.1016/j.avsg.2017.05.016
更新日期:2017-11-01 00:00:00