Fractal analysis of pulmonary arteries: the fractal dimension is lower in pulmonary hypertension.

Abstract:

:We analyzed the spatial structure of contact radiographs of barium-filled pulmonary arteries of rats raised in room air and in two environments that induce pulmonary arterial hypertension (PAH)--hypoxia and hyperoxia. We found that the spatial structure of the pulmonary arteries was fractal in both the control and the hypertensive lungs. The fractal dimension of the pulmonary arteries of the control lungs was 1.62 +/- 0.01 (mean +/- SEM), which is greater than that of both the hypoxic lungs 1.50 +/- 0.03 (p < 0.01) and the hyperoxic lungs 1.44 +/- 0.01 (p < 0.01). There was no significant difference between the hypoxic and hyperoxic lungs. The fractal dimension may be a useful clinical index to quantify pathologic changes in the pulmonary arterial tree.

journal_name

J Thorac Imaging

authors

Boxt LM,Katz J,Liebovitch LS,Jones R,Esser PD,Reid L

subject

Has Abstract

pub_date

1994-01-01 00:00:00

pages

8-13

issue

1

eissn

0883-5993

issn

1536-0237

journal_volume

9

pub_type

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