Thoracic manifestations of sickle cell disease.

Abstract:

:Sickle cell disease is the most common inherited disease in the African American population. Multiorgan pathologic features with a predilection for thoracic organs predominate. Acute cardiopulmonary diseases include acute chest syndrome, pneumonia, and left ventricular failure. Cardiomegaly, pleural effusions, pulmonary consolidation, pulmonary edema on chest radiographs, and ground-glass opacities on computed tomographs are characteristic. Chronic changes include sickle cell lung disease with lung fibrosis, pulmonary arterial hypertension, hyperkinetic circulation related to severe anemia, and thoracic skeletal abnormalities; the latter are H-shaped vertebrae, rib infarction, and extramedullary hematopoesis.

journal_name

J Thorac Imaging

authors

Leong CS,Stark P

doi

10.1097/00005382-199804000-00008

subject

Has Abstract

pub_date

1998-04-01 00:00:00

pages

128-34

issue

2

eissn

0883-5993

issn

1536-0237

journal_volume

13

pub_type

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