Abstract:
:We retrospectively evaluated the computed tomography (CT) findings in 20 patients with pulmonary drug toxicity that followed high-dose chemotherapy and autologous bone marrow transplantation (ABMT). Eighty-five patients with Stage II or III breast cancer that involved > or = 10 axillary lymph nodes were enrolled in a treatment protocol that included four cycles of standard-dose therapy (CAF) followed by one cycle of high-dose treatment (CPA/cDDP/BCNU). After chemotherapy, ABMT was performed. Twenty-six patients (31%) developed pulmonary drug toxicity. Serial thoracic CT studies were available in 20 of these 26 patients. All 20 patients exhibited clinical symptoms (i.e., dyspnea, nonproductive cough, and fever) and abnormal pulmonary function following transplantation. Thirteen patients had pathologically proven drug toxicity, and seven patients had clinical features and treatment responses highly suggestive of this diagnosis. Multiple sputum and blood cultures were negative in all patients. CT scans of 13 patients (65%) demonstrated scattered, predominantly peripheral ground-glass or consolidated opacities that occasionally looked nodular or masslike. Two patients (10%) had CT scans suggestive of pulmonary edema and in five patients (25%), the CT examinations revealed no significant abnormalities. Pleural effusions and adenopathy were uncommon. Pulmonary drug toxicity after high-dose chemotherapy and ABMT should be suspected in the appropriate clinical and radiographic setting, and therapy may be initiated on the basis of these observations.
journal_name
J Thorac Imagingjournal_title
Journal of thoracic imagingauthors
Patz EF Jr,Peters WP,Goodman PCdoi
10.1097/00005382-199421000-00017subject
Has Abstractpub_date
1994-04-01 00:00:00pages
129-34issue
2eissn
0883-5993issn
1536-0237journal_volume
9pub_type
杂志文章abstract::Before the advent of fast-scanning multidetector-row computed tomography (CT) technology, thoracic CT studies were exclusively used for the morphologic assessment of thoracic organs, as the concurrent examination of the heart was hampered by image degradation from cardiac motion artifacts. The introduction of fast rot...
journal_title:Journal of thoracic imaging
pub_type: 杂志文章,评审
doi:10.1097/RTI.0b013e3181e0f8c9
更新日期:2010-08-01 00:00:00
abstract:PURPOSE:The purpose of the study was to evaluate 70 kVp dual-source computed tomography pulmonary angiography (CTPA) with reduced iodine load in comparison with single-source 70 and 100 kVp CTPA with standard iodine load regarding image quality and radiation dose. MATERIALS AND METHODS:Three groups with 40 consecutive...
journal_title:Journal of thoracic imaging
pub_type: 杂志文章
doi:10.1097/RTI.0000000000000124
更新日期:2015-01-01 00:00:00
abstract:PURPOSE:The peri-infarct zone represents the morphologic substrate for reentry ventricular tachycardia after myocardial infarction, and its extent is a strong predictor of major cardiac events. Although delayed gadolinium enhancement magnetic resonance imaging (DGE-MRI) was shown to allow for detailed characterization ...
journal_title:Journal of thoracic imaging
pub_type: 杂志文章
doi:10.1097/RTI.0b013e3182125fb8
更新日期:2012-03-01 00:00:00
abstract::Since the publication of the Radiologic Diagnostic Oncology Group Report in 1991, the clinical application of pulmonary magnetic resonance imaging (MRI) in patients with lung cancer has been limited. In contrast, MRI for lung cancer has undergone continuous development, and several promising techniques have been intro...
journal_title:Journal of thoracic imaging
pub_type: 杂志文章,评审
doi:10.1097/RTI.0b013e31828d4234
更新日期:2013-05-01 00:00:00
abstract::Pulmonary capillary hemangiomatosis is a rare disorder that is characterized pathologically by formation of capillaries along alveolar walls that may ultimately invade the pulmonary parenchyma and pulmonary arteries. The clinic presentation overlaps that of primary pulmonary hypertension, but the natural history of pu...
journal_title:Journal of thoracic imaging
pub_type: 杂志文章
doi:10.1097/00005382-199801000-00012
更新日期:1998-01-01 00:00:00
abstract::Thoracic duct cysts are rare lesions presenting as mediastinal or supraclavicular masses. We report a case of a 77-year-old female who presented with a left supraclavicular mass. A cervical thoracic duct cyst was suspected after contrast-enhanced computed tomography (CT) of the neck and chest. Diagnosis was confirmed ...
journal_title:Journal of thoracic imaging
pub_type: 杂志文章
doi:10.1097/01.rti.0000148208.74252.84
更新日期:2005-05-01 00:00:00
abstract:PURPOSE:Cardiac fluorine-18-fluorodeoxyglucose (FDG) uptake is known to be variable in fasting oncologic positron emission tomography computed tomography studies. Increased posterolateral and basal FDG activity have been reported with the basal pattern ascribed to radiation injury. The purpose of this study was to inve...
journal_title:Journal of thoracic imaging
pub_type: 杂志文章
doi:10.1097/RTI.0b013e3182176675
更新日期:2012-07-01 00:00:00
abstract::Although rounded atelectasis was recognized in 1928, its relationship to fibrotic pleural disease almost has gone unnoticed. We present four cases of lobar rounded atelectasis that help to clarify this relationship. Rounded atelectasis is part of the spectrum of fibrous pleural disease. Any portion of lung may become ...
journal_title:Journal of thoracic imaging
pub_type: 杂志文章
doi:10.1097/00005382-199323000-00008
更新日期:1993-10-01 00:00:00
abstract:PURPOSE:Ultrashort echotime (UTE) sequences aim to improve the signal yield in pulmonary magnetic resonance imaging (MRI). We demonstrate the initial results of spiral 3-dimensional (3D) UTE-MRI for combined morphologic and functional imaging in pediatric patients. METHODS:Seven pediatric patients with pulmonary abnor...
journal_title:Journal of thoracic imaging
pub_type: 杂志文章
doi:10.1097/RTI.0000000000000537
更新日期:2021-01-01 00:00:00
abstract::Computed tomography (CT) of the chest provides important information toward the diagnosis of drug-induced lung disease. CT's ability to demonstrate subtle parenchymal and pleural changes, small nodules, and adenopathy is valuable in the early detection of drug-related reactions. CT is also of value in monitoring the a...
journal_title:Journal of thoracic imaging
pub_type: 杂志文章,评审
doi:10.1097/00005382-199101000-00008
更新日期:1991-01-01 00:00:00
abstract::The current Dana Point Classification system (2009) distinguishes elevation of pulmonary arterial pressure into pulmonary arterial hypertension (PAH) and pulmonary hypertension. Fortunately, PAH is not a common disease. However, with the aging of the First World's population, heart failure has become an important outc...
journal_title:Journal of thoracic imaging
pub_type: 杂志文章,评审
doi:10.1097/RTI.0b013e31828d5c48
更新日期:2013-05-01 00:00:00
abstract::Epipericardial fat necrosis is an unusual clinical condition of unknown etiology first reported in the literature in 1957. It presents as an acute onset of chest pain and a well-defined juxtacardiac mass. Computed tomographic findings of this condition demonstrate a fat-attenuation mass that resolves over time. We pre...
journal_title:Journal of thoracic imaging
pub_type: 杂志文章,评审
doi:10.1097/RTI.0b013e3181fa6d7c
更新日期:2011-11-01 00:00:00
abstract::Pneumatic nail guns are a tool used commonly in the construction industry and are widely available. Accidental injuries from nail guns are common, and several cases of suicide using a nail gun have been reported. Computed tomographic (CT) imaging, together with echocardiography, has been shown to be the gold standard ...
journal_title:Journal of thoracic imaging
pub_type: 杂志文章
doi:10.1097/RTI.0b013e31821bdaa0
更新日期:2012-09-01 00:00:00
abstract::Left ventricular assist devices are used as a bridge to recovery, a bridge to transplant, or a permanent alternative to cardiac transplant. This exhibit demonstrates the imaging appearance of commonly used left ventricular assist devices and their complications. ...
journal_title:Journal of thoracic imaging
pub_type: 杂志文章
doi:10.1097/01.rti.0000146623.32209.36
更新日期:2005-02-01 00:00:00
abstract:PURPOSE:The aim of this study was to evaluate the impact of percutaneous pulmonary valve implantation (PPVI) and surgical pulmonary valve replacement (SPVR) on biventricular and pulmonary valve function using cardiac magnetic resonance. MATERIALS AND METHODS:Thirty-five patients aged 20±8 years (mean±SD) underwent PPV...
journal_title:Journal of thoracic imaging
pub_type: 杂志文章
doi:10.1097/RTI.0000000000000272
更新日期:2017-11-01 00:00:00
abstract::Lung cancer is the leading cause of cancer death in the United States and worldwide. However, among the top 4 deadliest cancers, lung cancer is the only one not subject to routine screening. Optimism for an effective lung cancer-screening examination soared after the release of the National Lung Screening Trial result...
journal_title:Journal of thoracic imaging
pub_type: 杂志文章,评审
doi:10.1097/RTI.0000000000000119
更新日期:2015-01-01 00:00:00
abstract::A case of sarcoidosis demonstrating an unusual pattern of profuse micronodular calcification is presented. The striking similarity with the so-called pathognomonic appearance of pulmonary alveolar microlithiasis and the progressive deterioration of pulmonary function are emphasized. ...
journal_title:Journal of thoracic imaging
pub_type: 杂志文章
doi:
更新日期:1999-07-01 00:00:00
abstract::Recognizing atelectasis has always been a challenge. Atypical patterns further our knowledge of this subject. The lung has two mechanisms to help keep the lobes inflated: collateral ventilation and trapped nitrogen both tend to inflate the lungs when the airways are obstructed. Peripheral upper-lobe atelectasis resemb...
journal_title:Journal of thoracic imaging
pub_type: 杂志文章,评审
doi:
更新日期:1996-07-01 00:00:00
abstract::Exercise radionuclide ventriculography is commonly used in patients with coronary artery disease, for both diagnostic purposes and patient management decisions. Both applications are reviewed in this article. There has been much debate as to the diagnostic efficacy of this test. Four factors influence this determinati...
journal_title:Journal of thoracic imaging
pub_type: 杂志文章,评审
doi:10.1097/00005382-199007000-00008
更新日期:1990-07-01 00:00:00
abstract::Extrapleural administration of dilute contrast was used to facilitate biopsy of a posterior mediastinal mass. ...
journal_title:Journal of thoracic imaging
pub_type: 杂志文章
doi:10.1097/00005382-199904000-00005
更新日期:1999-04-01 00:00:00
abstract::Esophageal cancer, an uncommon neoplasm, has been increasing in incidence over the past few decades. Optimal management of patients is determined by the stage of disease at presentation, patient performance status, and location of the primary cancer. Recently, there has been increasing use of multimodality therapy in ...
journal_title:Journal of thoracic imaging
pub_type: 杂志文章,评审
doi:10.1097/00005382-200605000-00005
更新日期:2006-05-01 00:00:00
abstract:PURPOSE:The aim of this study was to evaluate the literature for articles assessing radiofrequency ablation (RFA) for pulmonary malignancy. MATERIALS AND METHODS:The "bottom-up" approach to evidence-based practice was applied by 2 reviewers to the retrieval and appraisal of original research articles published on pulm...
journal_title:Journal of thoracic imaging
pub_type: 杂志文章,评审
doi:10.1097/RTI.0b013e3181e48d5e
更新日期:2011-02-01 00:00:00
abstract:PURPOSE:To establish whether a relationship exists between computed tomography features of lung opacities in severely neutropenic patients and their Aspergillus or bacterial etiology. METHODS:Computed tomography scans of 124 patients with lung opacities larger than 5 mm occurring during severe (neutrophils <500/mm) an...
journal_title:Journal of thoracic imaging
pub_type: 杂志文章
doi:10.1097/RTI.0b013e31805f6a42
更新日期:2007-05-01 00:00:00
abstract::Following human immunodeficiency virus (HIV) infection, there is an ordered progression of immunologic abnormalities that results from the selective infection of the T4 helper/inducer subset of T lymphocytes. The loss of helper T-cell function disrupts both the cellular and humoral aspects of the immune response. The ...
journal_title:Journal of thoracic imaging
pub_type: 杂志文章,评审
doi:
更新日期:1991-09-01 00:00:00
abstract:SUMMARY:A 59-year-old man who underwent chest radiography to exclude pneumonia showed an irregular nodular shadow in the left lower lung. A subsequent CT scan revealed an irregularly shaped soft-tissue mass consisting of two components: a peripheral round mass with spiculated margins and a well-circumscribed branching ...
journal_title:Journal of thoracic imaging
pub_type: 杂志文章
doi:10.1097/00005382-200201000-00014
更新日期:2002-01-01 00:00:00
abstract:PURPOSE:Cardiac involvement is an important prognostic factor in sarcoidosis, and cardiovascular magnetic resonance (CMR) imaging with late gadolinium enhancement (LGE) can facilitate the identification of cardiac sarcoidosis (CS). In patients with CS, we investigated LGE characteristics and their relationship with lef...
journal_title:Journal of thoracic imaging
pub_type: 杂志文章
doi:10.1097/RTI.0b013e3182761830
更新日期:2013-01-01 00:00:00
abstract::Pulmonary artery dissection is a rare but life-threatening disease, which has mainly been diagnosed at postmortem examination rather than in living patients. Herein we report an unusual case of pulmonary artery dissection involving the right and left pulmonary arteries with Eisenmenger syndrome confirmed by multidetec...
journal_title:Journal of thoracic imaging
pub_type: 杂志文章
doi:10.1097/RTI.0b013e3181c65af5
更新日期:2010-11-01 00:00:00
abstract::Immunocompromised patients are encountered with increasing frequency in clinical practice. In addition to the acquired immunodeficiency syndrome (AIDS), therapy for malignant disease, and immune suppression for solid organ transplants, patients are now rendered immunosuppressed by advances in treatment for a wide vari...
journal_title:Journal of thoracic imaging
pub_type: 杂志文章,评审
doi:10.1097/RTI.0000000000000342
更新日期:2018-09-01 00:00:00
abstract:SUMMARY:To assess the radiologic findings of systemic arterial supply to the normal basal segments of the left lower lobe, chest radiographs and CT scans of all 11 patients were reviewed retrospectively by two chest radiologists. On posteroanterior chest radiographs (n = 11), the anomalous systemic artery arising from ...
journal_title:Journal of thoracic imaging
pub_type: 杂志文章
doi:10.1097/00005382-200201000-00004
更新日期:2002-01-01 00:00:00
abstract::We present a case of pulmonary sarcoidosis showing the "reversed halo sign" on high-resolution computed tomography (HRCT). A 27-year-old man presented with nonproductive cough and high fever lasting for 3 weeks. A chest radiograph showed multiple areas of consolidation and cavitary shadows in the lungs. The HRCT showe...
journal_title:Journal of thoracic imaging
pub_type: 杂志文章
doi:10.1097/RTI.0b013e318190476f
更新日期:2009-02-01 00:00:00