Recurrent rectal cancer: diagnosis with dynamic MR imaging.

Abstract:

PURPOSE:To evaluate whether dynamic magnetic resonance (MR) imaging can increase the diagnostic accuracy in suspected local recurrence of rectal carcinoma. MATERIALS AND METHODS:Eighteen patients (seven men, 11 women, aged 26-78 years) with 19 suspect lesions were examined. T1-weighted (pre- and postcontrast) and T2-weighted spin-echo images were read by three observers. Computed tissue-specific enhancement parameters were obtained and displayed on gray-scale images (pharmacokinetic mapping). RESULTS:Reading of the spin-echo images yielded a sensitivity of 91%-100% (confidence interval, 67%, 100%), a specificity of 29%-43% (12%, 67%), and an accuracy of 71%-75% (48%, 91%). Analysis of the MR data showed greater (P = .0038) and faster (P = .0018) enhancement of malignant lesions (n = 12) compared with benign lesions (n = 7). CONCLUSION:Pharmacokinetic mapping of dynamic MR imaging data allows in vivo insight into tissue physiopathology, helping differentiate benign from malignant pelvic lesions in rectal cancer.

journal_name

Radiology

journal_title

Radiology

authors

Müller-Schimpfle M,Brix G,Layer G,Schlag P,Engenhart R,Frohmuller S,Hess T,Zuna I,Semmler W,van Kaick G

doi

10.1148/radiology.189.3.8234720

subject

Has Abstract

pub_date

1993-12-01 00:00:00

pages

881-9

issue

3

eissn

0033-8419

issn

1527-1315

journal_volume

189

pub_type

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