Abstract:
PURPOSE:To evaluate whether dynamic magnetic resonance (MR) imaging can increase the diagnostic accuracy in suspected local recurrence of rectal carcinoma. MATERIALS AND METHODS:Eighteen patients (seven men, 11 women, aged 26-78 years) with 19 suspect lesions were examined. T1-weighted (pre- and postcontrast) and T2-weighted spin-echo images were read by three observers. Computed tissue-specific enhancement parameters were obtained and displayed on gray-scale images (pharmacokinetic mapping). RESULTS:Reading of the spin-echo images yielded a sensitivity of 91%-100% (confidence interval, 67%, 100%), a specificity of 29%-43% (12%, 67%), and an accuracy of 71%-75% (48%, 91%). Analysis of the MR data showed greater (P = .0038) and faster (P = .0018) enhancement of malignant lesions (n = 12) compared with benign lesions (n = 7). CONCLUSION:Pharmacokinetic mapping of dynamic MR imaging data allows in vivo insight into tissue physiopathology, helping differentiate benign from malignant pelvic lesions in rectal cancer.
journal_name
Radiologyjournal_title
Radiologyauthors
Müller-Schimpfle M,Brix G,Layer G,Schlag P,Engenhart R,Frohmuller S,Hess T,Zuna I,Semmler W,van Kaick Gdoi
10.1148/radiology.189.3.8234720subject
Has Abstractpub_date
1993-12-01 00:00:00pages
881-9issue
3eissn
0033-8419issn
1527-1315journal_volume
189pub_type
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