Acantholytic dyskeratosis occurring within an epidermal nevus.

Abstract:

:A 25-year-old woman presented with a large area of flesh-colored verrucous plaques following the lines of Blaschko on the left side of the body that had been present since 6 months of age. The plaques had been stable and grew proportionately with the patient's body until she reached 20 years of age when they began to thicken and enlarge. Her medical and family history was unremarkable. A shave biopsy revealed a papillomatous epidermis with 3 discrete foci of acantholytic dyskeratosis, with corps ronds and grains that were similar to the histologic findings of Darier disease (DD). Epidermolytic hyperkeratosis was not identified. Our patient's lack of a family history of DD, early-onset disease, and linear presentation along the lines of Blaschko all favored a diagnosis of acantholytic dyskeratotic epidermal nevi (ADEN) versus localized DD.

journal_name

Cutis

journal_title

Cutis

authors

Khetarpal S,Tarbox M,Tuthill RJ,Vidimos A

subject

Has Abstract

pub_date

2013-08-01 00:00:00

pages

80-2

issue

2

eissn

0011-4162

issn

2326-6929

journal_volume

92

pub_type

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