Abstract：
:Numerous investigators have attempted to enhance the survival of ischemic experimental skin flaps using various pharmacologic manipulations. Recently, the authors' laboratory demonstrated the beneficial effect of iloprost, a stable PGI2 analogue, as a post-ischemic perfusion washout, in improving the survival of ischemic skin flaps. The rat unilateral abdominal skin flap, based on the superficial epigastric vessels, was utilized in this study involving 30 animals. The animals were divided into three different treatment groups, with ischemic periods of 16 and 18 hr. Perfusion washouts were performed at the completion of the various ischemic periods. Alzet osmotic pumps were used to deliver a continuous systemic infusion of iloprost for 7 days postoperatively. The groups consisted of the following: Group 1 (single ILO)--perfusion washout with iloprost only; Group 2 (continuous LD ILO)--low-dose systemic iloprost infusion (0.066 mcg/kg/min) and perfusion washout with iloprost; and Group 3 (continuous HD ILO)--high-dose systemic iloprost infusion (0.1 mcg/kg/min) and perfusion washout with iloprost. The percentage of flap survival was assessed on postoperative day 7. Skin flaps of the animals receiving the continuous systemic infusion of iloprost were noted to have varying percentages of survival, while skin flaps undergoing perfusion washout only were found to have either complete survival using a continuous systemic infusion of iloprost, compared to iloprost perfusion washout alone. In addition, the hypotensive side effects of systemic iloprost infusion limit its use in the rat skin-flap model.
journal_name
J Reconstr Microsurgjournal_title
Journal of reconstructive microsurgeryauthors
Forman DL,Shah DK,Zhang WX,Senderoff DM,Israeli D,Urken ML,Weinberg Hdoi
10.1055/s-2007-1006549subject
Has Abstractpub_date
1995-09-01 00:00:00pages
339-44issue
5eissn
0743-684Xissn
1098-8947journal_volume
11pub_type
杂志文章abstract：:Although often a life-saving therapeutic maneuver, there is minimal data available that details the effects of intraoperative packed red blood cell transfusion (IOT) after microvascular free tissue transfer. The National Surgical Quality Improvement Program database was queried to identify all patients who underwent m...
journal_title：Journal of reconstructive microsurgery
pub_type： 杂志文章,多中心研究
doi：10.1055/s-0033-1357275
更新日期：2014-02-01 00:00:00
abstract：BACKGROUND:The purpose of this study is to identify whether intraoperative use of vasoactive medications increases the risk of free flap failure or complications through a systematic review and meta-analysis. MATERIALS AND METHODS:PubMed/MEDLINE, EMBASE, and Scopus databases were searched for studies published through...
journal_title：Journal of reconstructive microsurgery
pub_type： 杂志文章,meta分析,评审
doi：10.1055/s-0035-1563381
更新日期：2016-02-01 00:00:00
abstract：:The objective of this article is to discuss the significance of predicting the injury degree of the thoracodorsal nerve by intraoperative electrophysiological examination in the C7 nerve root transfer for brachial plexus injury. Each trunk of the brachial plexus followed by each bundle of C7 was stimulated before the ...
journal_title：Journal of reconstructive microsurgery
pub_type： 杂志文章
doi：10.1055/s-0030-1263291
更新日期：2011-01-01 00:00:00
abstract：:In recent years microvascular free tissue transfer has become a well accepted reconstructive technique. The current trend in flap research seems to be the development of more refined flaps to meet specific needs with minimal donor site morbidity. The internal oblique muscle provides a broad, thin, well-vascularized fl...
journal_title：Journal of reconstructive microsurgery
pub_type： 杂志文章
doi：10.1055/s-2007-1007012
更新日期：1986-01-01 00:00:00
abstract：:Experiments in rats, introducing the proximal and distal stumps of tibial and sural nerves into a vein graft, showed by acetylcholinesterase and toluidine blue staining that sensory and motor fibers mix inside the vein graft, but that nevertheless they are able to select their distal targets correctly. The authors' hy...
journal_title：Journal of reconstructive microsurgery
pub_type： 杂志文章
doi：10.1055/s-2007-1006969
更新日期：1987-01-01 00:00:00
abstract：:Posttraumatic infected massive bone defects in lower extremities are difficult to repair because they frequently exhibit massive bone and/or soft tissue defects, serious bone infection, and excessive scar proliferation. This study aimed to determine whether these defects could be classified and repaired at a single st...
journal_title：Journal of reconstructive microsurgery
pub_type： 杂志文章
doi：10.1055/s-0033-1348064
更新日期：2013-11-01 00:00:00
abstract：:The lateral forearm flap is being increasingly used for covering minor-to-moderate-sized defects for which soft and thin skin is required. Within the framework of an anatomic study carried out on 28 cadaveric arms, the authors investigated the principal artery that supplies blood to this flap namely, the posterior rad...
journal_title：Journal of reconstructive microsurgery
pub_type： 杂志文章
doi：10.1055/s-2000-7537
更新日期：2000-01-01 00:00:00
abstract：:Nerve transection using rat sciatic nerves was employed to observe morphologic changes in the periodic denervation of Pacinian corpuscles. During periods of from 1 to 20 weeks after surgery, a total of 15 corpuscles were obtained under the operating microscope and processed for morphologic analysis using light and ele...
journal_title：Journal of reconstructive microsurgery
pub_type： 杂志文章
doi：10.1055/s-2007-1000101
更新日期：1999-05-01 00:00:00
abstract：:The purpose of this investigation was to evaluate the ability of a specific growth factor combination, nerve growth factor (NGF) and ciliary neurotrophic factor (CNTF), to enhance peripheral nerve regeneration. Eight groups of eight Sprague-Dawley rats underwent repair of a nerve gap defect: Group A (immediate repair)...
journal_title：Journal of reconstructive microsurgery
pub_type： 杂志文章
doi：10.1055/s-2004-833499
更新日期：2004-08-01 00:00:00
abstract：BACKGROUND: With the technological advances, microsurgery has evolved to the era of supermicrosurgery since its inception. With the popularization of these flaps, proficiency in using tools such as color Doppler ultrasound (CDU) has become crucial. Despite the increased interest, studies regarding the role of ultrasoun...
journal_title：Journal of reconstructive microsurgery
pub_type： 杂志文章
doi：10.1055/s-0040-1709479
更新日期：2020-09-01 00:00:00
abstract：:The high demand for microsurgical skills in those without a strong microsurgery background limits the application of the rat aortic transplant model to transplantation research. In this study, we established a rat aortic transplant model using a hydrodissection technique as a minimal-touch technique in vessel dissecti...
journal_title：Journal of reconstructive microsurgery
pub_type： 杂志文章
doi：10.1055/s-0031-1278710
更新日期：2011-07-01 00:00:00
abstract：:A method of fixation for replanted digits is described. It consists of axial fixation with a wire passed longitudinally through the replanted digit, supplemented with a transverse wire passed across all the digits. In this way, splinting is provided and rotation is controlled. The method is simple, rapidly applied, an...
journal_title：Journal of reconstructive microsurgery
pub_type： 杂志文章
doi：10.1055/s-2007-1007067
更新日期：1984-10-01 00:00:00
abstract：:In a comparative study, it was demonstrated that sutureless, laser-welded, end-to-end anastomoses in the rat femoral artery and vein are feasible, using either CO2 or Nd:YAG laser. Conventional microsurgical suture anastomoses served as the controls. Patency rates in experimental animals and controls were equal (96 to...
journal_title：Journal of reconstructive microsurgery
pub_type： 杂志文章
doi：10.1055/s-2007-1006647
更新日期：1993-05-01 00:00:00
abstract：:9-0 absorbable polydioxanone (PDS) has been compared to 9-0 nonabsorbable Prolene in order to evaluate any advantages of either suture in microvascular surgery. In each of 29 rats, one carotid artery was anastomosed end-to-end with PDS and the other with Prolene. Specimens were harvested 48 hr, 14 days, and three, and...
journal_title：Journal of reconstructive microsurgery
pub_type： 杂志文章
doi：10.1055/s-2007-1006833
更新日期：1990-07-01 00:00:00
abstract：:The authors examined the effects of end-to-side neurorrhaphy for reinnervation of the musculocutaneous nerve (Group A) which innervates the biceps muscle, compared to reinnervation of the median nerve which innervates multiple muscles in a rat model. Additionally, end-to-end neurorrhaphy to the musculocutaneous nerve ...
journal_title：Journal of reconstructive microsurgery
pub_type： 杂志文章
doi：10.1055/s-2006-947151
更新日期：2000-08-01 00:00:00
abstract：:Background The lateral branch of the thoracodorsal nerve (LBTN) is used for nerve transfer in facial, musculocutaneous, axillary nerve injuries and for irreparable C5, C6 spinal nerve lesions and accessory nerve defects. For a successful surgical outcome, the nerve to be used in nerve transfer should be of adequate le...
journal_title：Journal of reconstructive microsurgery
pub_type： 杂志文章
doi：10.1055/s-0036-1579541
更新日期：2016-06-01 00:00:00
abstract：:Eleven patients with paralysis of muscle groups in the upper or lower extremity were clinically diagnosed after previous proximal direct trauma to the corresponding peripheral nerves, without complete nerve disruption. Patients were seen within an average of 8 months after trauma (minimum 3 months and maximum 2 years ...
journal_title：Journal of reconstructive microsurgery
pub_type： 杂志文章
doi：10.1055/s-2007-1000087
更新日期：1999-04-01 00:00:00
abstract：:The use of interposition vein grafts has been associated in the literature with a high complication and flap failure rate. Ninety-three vein grafts in 55 patients over a 46-month period were analyzed to evaluate the clinical reliability of vein grafts in a predominantly trauma patient population (37/55). Fifty-two art...
journal_title：Journal of reconstructive microsurgery
pub_type： 杂志文章
doi：10.1055/s-2007-1006446
更新日期：1996-01-01 00:00:00
abstract：:Four methods of nerve terminolateral neurorrhaphy (TLN) were studied in rat experimental model. In Group A, the distal end of a severed peroneal nerve was sutured end-to-side with an intact tibial nerve trunk, without removal of the tibial epineurium at the suture site. In Group B, the distal end of a severed peroneal...
journal_title：Journal of reconstructive microsurgery
pub_type： 杂志文章
doi：10.1055/s-2008-1063938
更新日期：1997-01-01 00:00:00
abstract：BACKGROUND: Injury or compression of a sensory nerve is an under-reported source of disabling pain in the lower limb. It is known that peripheral nerve microsurgeons can reconstruct and rewire injured nerves to relieve chronic pain but this option remains not completely understood and ignored by most orthopaedic surgeo...
journal_title：Journal of reconstructive microsurgery
pub_type： 杂志文章
doi：10.1055/s-0040-1717100
更新日期：2020-10-07 00:00:00
abstract：:Multilayered tubes fabricated from human amnion were placed subcutaneously and/or longitudinally in contact with an axial artery and vein in rats. Histologic evaluation at the third postoperative week showed that the tubes had incorporated with the surrounding fibrovascular tissue. New capillary formation within the t...
journal_title：Journal of reconstructive microsurgery
pub_type： 杂志文章
doi：10.1055/s-2007-1006749
更新日期：1993-11-01 00:00:00
abstract：BACKGROUND: Subfascial anterolateral thigh (ALT) flap thickness can be problematic with regards to bulk, oral competence, shoe-fit, or as a potential source of recurrent wound breakdown. We have utilized distinct upper thigh fascial planes to fashion thin (suprafascial) or super-thin (periscarpal) ALT flaps to improve ...
journal_title：Journal of reconstructive microsurgery
pub_type： 杂志文章
doi：10.1055/s-0037-1607426
更新日期：2018-03-01 00:00:00
abstract：:Endorectal ileo-anal anastomosis has become a mainstay of continent bowel reconstruction after total colectomy. However, the procedure is often aborted because of lack of vessel length for the formation of the ileal pouch. The use of microsurgical techniques to lengthen mesenteric vessels and to allow completion of th...
journal_title：Journal of reconstructive microsurgery
pub_type： 杂志文章
doi：10.1055/s-2007-1006944
更新日期：1988-10-01 00:00:00
abstract：BACKGROUND:Nonunions in the upper extremity are challenging for the reconstructive surgeon. The evolution of microsurgical techniques has allowed for the reliable use of free vascularized bone flaps. METHODS:In a retrospective study, patients with challenging upper limb nonunions who underwent free vascularized cortic...
journal_title：Journal of reconstructive microsurgery
pub_type： 杂志文章
doi：10.1055/s-0034-1390045
更新日期：2015-02-01 00:00:00
abstract：BACKGROUND:Open injuries of the Achilles tendon, which can be complicated by skin and bone injuries, continue to be a great challenge for surgeons. This study aims to report our experience with treatment of open Achilles tendon defects, focusing on the injury mechanisms, soft tissue coverage and late complications. ME...
journal_title：Journal of reconstructive microsurgery
pub_type： 杂志文章
doi：10.1055/s-0033-1358787
更新日期：2014-10-01 00:00:00
abstract：:This paper describes a new technique for microvascular anastomosis, which involves the overlapping of the adventitias of the two ends of a severed blood vessel, and then painting a cyanoacrylate adhesive on the outer surface of the vessel around the anastomosed part. Sixteen anastomoses were performed in both radial a...
journal_title：Journal of reconstructive microsurgery
pub_type： 杂志文章
doi：10.1055/s-2004-824890
更新日期：2004-05-01 00:00:00
abstract：:This study attempted to re-establish vascularization to canine allograft bone by means of the introduction of a pedicle in the medullary canal with a capillary network. The experiment showed basically that the introduction of arteries and veins with a capillary network into the medullary canal of an allograft femur pr...
journal_title：Journal of reconstructive microsurgery
pub_type： 杂志文章
doi：10.1055/s-2007-1006767
更新日期：1991-04-01 00:00:00
abstract：:The purpose of this study was to evaluate the use of free-tissue transfers for the reconstruction of radiation-induced complex injuries. The case files for patients who underwent reconstruction for radiation-induced injuries between May 1988 and November 1995 at The University of Texas M.D. Anderson Cancer Center were...
journal_title：Journal of reconstructive microsurgery
pub_type： 杂志文章
doi：10.1055/s-2007-1000187
更新日期：1998-07-01 00:00:00
abstract：:Sixteen arterialized venous flaps, free flaps that have arterial blood only flowing through the vein of the flap, were applied to reconstruct skin defects of the big toe resulting from wrap-around flap transfers. There were seven complete successes, six partial successes, and three complete failures. The clinical cour...
journal_title：Journal of reconstructive microsurgery
pub_type： 杂志文章
doi：10.1055/s-2007-1006756
更新日期：1991-01-01 00:00:00
abstract：BACKGROUND:While many potential donor sites have been described for fascial (fascia-only) flaps, a fascial flap harvested from the anterolateral thigh (ALT) donor site has not gained popularity, likely because of concerns regarding inadequate perfusion of the deep fascia. However, recent clinical experience demonstrate...
journal_title：Journal of reconstructive microsurgery
pub_type： 杂志文章
doi：10.1055/s-0033-1361843
更新日期：2014-11-01 00:00:00
