Short-term intravenous antimicrobial prophylaxis for elective rectal cancer surgery: results of a prospective randomized non-inferiority trial.

Abstract:

PURPOSE:To investigate the non-inferiority of postoperative single-dose intravenous antimicrobial prophylaxis to multiple-dose intravenous antimicrobial prophylaxis in terms of the incidence of surgical site infections (SSIs) in patients undergoing elective rectal cancer surgery by a prospective randomized study. METHODS:Patients undergoing elective surgery for rectal cancer were randomized to receive a single intravenous injection of flomoxef (group 1) or five additional doses (group 2) of flomoxef after the surgery. All the patients had received preoperative oral antibiotic prophylaxis (kanamycin and erythromycin) after mechanical cleansing within 24 h prior to surgery, and had received intravenous flomoxef during surgery. RESULTS:A total of 279 patients (including 139 patients in group 1 and 140 in group 2) were enrolled in the study. The incidence of SSIs was 13.7% in group 1 and 13.6% in group 2 (difference [95% confidence interval]: -0.2% [-0.9 to 0.7%]). CONCLUSION:The incidence of SSIs was not significantly different in patients undergoing elective rectal surgery who were treated using a single dose of postoperative antibiotics compared to those treated using multiple-dose antibiotics when preoperative mechanical and chemical bowel preparations were employed.

journal_name

Surg Today

journal_title

Surgery today

authors

Ishibashi K,Ishida H,Kuwabara K,Ohsawa T,Okada N,Yokoyama M,Kumamoto K

doi

10.1007/s00595-013-0695-1

subject

Has Abstract

pub_date

2014-04-01 00:00:00

pages

716-22

issue

4

eissn

0941-1291

issn

1436-2813

journal_volume

44

pub_type

杂志文章,随机对照试验
  • Primary localized amyloidosis of the small intestine presenting as an intestinal pseudo-obstruction: report of a case.

    abstract::A 47-year-old man with primary amyloidosis confined to the small intestine is reported. Thickening of the folds and multiple polypoid protrusions were found in the duodenum by upper gastrointestinal endoscopy. Because the patient presented with a persistent intestinal pseudo-obstruction, partial jejunectomy was perfor...

    journal_title:Surgery today

    pub_type: 杂志文章

    doi:10.1007/PL00022938

    authors: Deguchi M,Shiraki K,Okano H,Yamanaka T,Ito N,Takase K,Nakano T

    更新日期:2001-01-01 00:00:00

  • The dynamics and clinical significance of alpha 2 plasmin inhibitor-plasmin complex and thrombin-antithrombin complex in postoperative pleural effusion following a pulmonary lobectomy.

    abstract:PURPOSE:The overall incidence of postoperative alveolar air leakage (AAL) remains high; however, the mechanism regarding how to adequately heal such postoperative AAL remains to be elucidated. The aim of this study was to determine any correlations between the activity of the fibrinolytic and coagulation system in the ...

    journal_title:Surgery today

    pub_type: 杂志文章

    doi:10.1007/s00595-008-3865-9

    authors: Shoji F,Yano T,Yoshino I,Kawano D,Takenaka T,Miura N,Ito K,Morodomi Y,Maehara Y

    更新日期:2009-01-01 00:00:00

  • Repeated colon penetration by an ingested fish bone: report of a case.

    abstract::A 78-year-old man was admitted to Kumamoto Rosai Hospital with right lower abdominal pain. Abdominal computed tomography (CT) showed penetration of the cecum by a foreign body, which looked like a fish bone, as well as thickening of the right lower abdominal wall. We made an initial diagnosis of penetration of the col...

    journal_title:Surgery today

    pub_type: 杂志文章

    doi:10.1007/s00595-007-3629-y

    authors: Okuma T,Nagamoto N,Tanaka E,Yoshida Y,Inoue K,Baba H

    更新日期:2008-01-01 00:00:00

  • A new method of performing continuous intraabdominal drainage after pancreaticoduodenectomy.

    abstract::Dehiscence of the pancreaticoenterostomy is one of the most feared, yet common, postoperative complications following pancreaticoduodenectomy (PD). We report herein a new technique we developed for performing continuous intraabdominal suction drainage (CISD) following PD. This method of CISD involves positioning an 18...

    journal_title:Surgery today

    pub_type: 临床试验,杂志文章

    doi:10.1007/BF00311482

    authors: Kayahara M,Nagakawa T,Ueno K,Ohta T,Miyazaki I

    更新日期:1995-01-01 00:00:00

  • Primary lung cancer occurring concomitantly with the cicatrized and calcified ova of a parasite: report of a case.

    abstract::We report herein a rare case of primary lung cancer that occurred concomitantly with the calcified ova of a parasite. A 58-year-old man was referred to our department after a pulmonary abnormal shadow had been seen on a chest X-ray done at mass screening. A transbronchial lung biopsy (TBLB) revealed the calcified ova ...

    journal_title:Surgery today

    pub_type: 杂志文章

    doi:10.1007/s005950170137

    authors: Hanagiri T,Tsuda I,Tsukamoto T,Nagasako T,Kobayashi H,Hattori M,Kawamura K,Ogasawara K,Manabe K,Uchino J

    更新日期:2001-01-01 00:00:00

  • Impact of cardiopulmonary complications of lung cancer surgery on long-term outcomes.

    abstract:PURPOSE:The impact of postoperative cardiopulmonary complications on long-term outcomes has not been established. We investigated the effects of acute postoperative cardiopulmonary complications not only on cancer recurrence, but also on cardiovascular or respiratory events in the chronic phase after lung cancer surger...

    journal_title:Surgery today

    pub_type: 杂志文章

    doi:10.1007/s00595-014-1032-z

    authors: Nojiri T,Inoue M,Takeuchi Y,Maeda H,Shintani Y,Sawabata N,Hamasaki T,Okumura M

    更新日期:2015-06-01 00:00:00

  • Short-term outcomes of laparoscopic surgery for Crohn's disease patients treated with anti-tumor necrosis factor alpha agents.

    abstract:PURPOSE:The impact of anti-tumor necrosis factor alpha (TNFα) treatment for Crohn's disease (CD) on surgical outcomes is still controversial. The aim of this study was to assess the feasibility of laparoscopic surgery for CD patients treated preoperatively with anti-TNFα agents. METHODS:We investigated, retrospectivel...

    journal_title:Surgery today

    pub_type: 杂志文章

    doi:10.1007/s00595-016-1375-8

    authors: Hata T,Mizushima T,Osawa H,Takahashi H,Haraguchi N,Nishimura J,Hata T,Takemasa I,Ikenaga M,Nakajima K,Yamamoto H,Murata K,Doki Y,Mori M

    更新日期:2017-03-01 00:00:00

  • Thymic papillo-tubular adenocarcinoma containing a cyst: report of a case.

    abstract::We report a case of thymic papillo-tubular adenocarcinoma in a 55-year-old man, who had no symptoms. Sternotomy revealed a tumor in the anterior mediastinum, tightly adhered to the pericardium. It was resected completely. Interestingly, the tumor contained a unilocular cyst filled with mucinous fluid, suggesting that ...

    journal_title:Surgery today

    pub_type: 杂志文章

    doi:10.1007/s00595-012-0161-5

    authors: Teramoto K,Kawaguchi Y,Hori T,Ishida M,Hashimoto M,Kitamura S,Motoishi M,Hanaoka J,Tezuka N,Okabe H

    更新日期:2012-10-01 00:00:00

  • Impact of esophageal flexion level on the surgical outcome in patients with sigmoid esophageal achalasia.

    abstract:PURPOSE:Esophageal achalasia can be roughly divided into non-sigmoid and sigmoid types. Laparoscopic surgery has been reported to be less than optimally effective for sigmoid type. The aim of this study was to examine the impact of the esophageal flexion level on the clinical condition and surgical outcomes of patients...

    journal_title:Surgery today

    pub_type: 杂志文章

    doi:10.1007/s00595-017-1519-5

    authors: Tsuboi K,Omura N,Yano F,Hoshino M,Yamamoto SR,Akimoto S,Masuda T,Kashiwagi H,Yanaga K

    更新日期:2017-11-01 00:00:00

  • Risk quantification for pulmonary complications after lung cancer surgery.

    abstract:PURPOSE:The purpose of this study was to identify the risk factors for postoperative pulmonary complications and to develop a scoring system to predict the surgical outcomes in lung cancer patients. METHODS:Clinical data were collected from January 1990 to March 2007 for 1713 patients who underwent lung cancer surgery...

    journal_title:Surgery today

    pub_type: 杂志文章

    doi:10.1007/s00595-009-4182-7

    authors: Sekine Y,Suzuki H,Nakajima T,Yasufuku K,Yoshida S

    更新日期:2010-11-01 00:00:00

  • Acute small bowel obstruction secondary to ileal endometriosis: report of a case.

    abstract::We report a case of acute small bowel obstruction occurring secondary to endometriosis of the terminal ileum. Ileal endometriosis is a rare condition that can cause acute small bowel obstruction. As this case and others in the literature highlight, establishing a preoperative diagnosis is very difficult due to the vag...

    journal_title:Surgery today

    pub_type: 杂志文章

    doi:10.1007/s00595-003-2613-4

    authors: Ridha JR,Cassaro S

    更新日期:2003-01-01 00:00:00

  • Salvage lymphadenectomy of the right recurrent nerve node with tracheal involvement after definitive chemoradiation therapy for esophageal squamous cell carcinoma: report of two cases.

    abstract::Thoracic esophageal cancers frequently metastasize to the right recurrent nerve nodes (RRNNs). In fact, huge RRNNs invading the trachea sometimes remain after definitive chemoradiation therapy (CRT), despite complete remission of the primary lesion. We performed salvage lymphadenectomy of a large RRNN combined with pa...

    journal_title:Surgery today

    pub_type: 杂志文章

    doi:10.1007/s00595-006-3447-7

    authors: Doki Y,Yasuda T,Miyata H,Fujiwara Y,Takiguchi S,Yamasaki M,Makari Y,Matsuyama J,Masuoka T,Monden M

    更新日期:2007-01-01 00:00:00

  • Candida esophagitis complicated by an esophago-airway fistula: report of a case.

    abstract::Candida esophagitis rarely involves life-threatening complications, such as necrosis, perforation, or fistula formation between the esophagus and the airway. We herein report a case of Candida esophagitis complicated by esophagobronchial and esophagopulmonary fistulas. The patient in our study was a 70-year-old man wi...

    journal_title:Surgery today

    pub_type: 杂志文章

    doi:10.1007/s00595-009-3958-0

    authors: Kanzaki R,Yano M,Takachi K,Ishiguro S,Motoori M,Kishi K,Miyashiro I,Ishikawa O,Imaoka S

    更新日期:2009-01-01 00:00:00

  • Clinical evaluation of leukocyte filtration as an alternative anti-inflammatory strategy to aprotinin in high-risk patients undergoing coronary revascularization.

    abstract:PURPOSE:The use of aprotinin in cardiac surgery is associated with overriding safety concerns. Therefore, there is increased research on alternatives. This study investigated the relative benefits of strategic leukofiltration on polymer-coated extracorporeal circuits (ECC), aprotinin, and combined therapy in high-risk ...

    journal_title:Surgery today

    pub_type: 杂志文章,随机对照试验

    doi:10.1007/s00595-011-0012-9

    authors: Farsak B,Gunaydin S,Yildiz U,Sari T,Zorlutuna Y

    更新日期:2012-04-01 00:00:00

  • Surgical treatment of chronic intestinal pseudo-obstruction: report of three cases.

    abstract::We report the cases of three patients with chronic intestinal pseudo-obstruction (CIP) whose quality of life (QOL) was improved by palliative surgery in combination with home parenteral nutrition (HPN). Loop enterostomy and shortening of the gastrointestinal tract was performed with good results in all three patients ...

    journal_title:Surgery today

    pub_type: 杂志文章

    doi:10.1007/s005950300011

    authors: Shibata C,Naito H,Funayama Y,Fukushima K,Hashimoto A,Kitayama T,Nagao M,Matsuno S,Sasaki I

    更新日期:2003-01-01 00:00:00

  • Videothoracoscopic surgery for thoracic neurogenic tumors: a 7-year experience.

    abstract::While videothoracoscopic surgery has rapidly become accepted as an effective method of performing minimally invasive surgery, the advantages and feasibility of using this surgical technique for the treatment of neurogenic tumors of the thorax are not yet well defined. Between August 1992 and May 1999, 15 solitary thor...

    journal_title:Surgery today

    pub_type: 杂志文章

    doi:10.1007/s005950070016

    authors: Sakumoto N,Inafuku S,Shimoji H,Nomura K,Honma K,Kawabata T,Ohta M,Kuniyoshi M,Ishikawa K,Genka K

    更新日期:2000-01-01 00:00:00

  • Optimal sutures for use in the abdomen: an evaluation based on the formation of adhesions and abscesses.

    abstract:PURPOSE:This study explored the optimal suture materials for use in the peritoneal cavity based on the formation of adhesions and abscesses under clean and contaminated conditions. METHODS:The parietal peritoneum and muscle layer of rats were incised. The incision was followed by interrupted suturing in the clean grou...

    journal_title:Surgery today

    pub_type: 杂志文章

    doi:10.1007/s00595-012-0249-y

    authors: Ishikawa K,Sadahiro S,Tanaka Y,Suzuki T,Kamijo A,Tazume S

    更新日期:2013-04-01 00:00:00

  • Systematic review of the implementation of simulation training in surgical residency curriculum.

    abstract:PURPOSE:We reviewed the literature regarding the specific methods and strategies for implementing simulation-based training into the modern surgical residency curriculum. Residency programs are still struggling with how best to implement it into their curricula from a practical viewpoint. METHODS:A systematic review w...

    journal_title:Surgery today

    pub_type: 杂志文章,meta分析,评审

    doi:10.1007/s00595-016-1455-9

    authors: Kurashima Y,Hirano S

    更新日期:2017-07-01 00:00:00

  • The development of a small bowel volvulus in the early postoperative period following a distal gastrectomy: report of a case.

    abstract::A 51-year-old Japanese man who underwent a standard distal gastrectomy for cancer of the stomach developed abdominal pain when oral intake was commenced on the 6th postoperative day after an uneventful postoperative course. Complete obstruction of the jejunum led to a sudden deterioration in his general condition and ...

    journal_title:Surgery today

    pub_type: 杂志文章

    doi:10.1007/BF01367459

    authors: Sakamoto T,Miyata M,Nakamuro M,Izukura M,Kamiike W,Matsuda H

    更新日期:1994-01-01 00:00:00

  • Long-term effect of a thoracoscopic stapled bullectomy alone for preventing the recurrence of primary spontaneous pneumothorax.

    abstract:PURPOSE:The purpose of this retrospective study was to determine the long-term efficacy of a stapled bullectomy without any symphysial procedures under videoassisted thoracoscopic surgery (VATS). METHODS:A total of 121 sides of 112 patients who underwent a stapled bullectomy alone for primary spontaneous pneumothorax ...

    journal_title:Surgery today

    pub_type: 杂志文章

    doi:10.1007/s00595-008-3934-0

    authors: Nakanishi K

    更新日期:2009-01-01 00:00:00

  • Robotic versus laparoscopic surgery for rectal cancer: an overview of systematic reviews with quality assessment of current evidence.

    abstract:PURPOSE:The clinical benefits of robotic surgery for patients with rectal cancer have been reported and many systematic reviews have been published. However, they have investigated a variety of outcomes and differ remarkably in quality. In this overview, we summarize the findings of these reviews and evaluate their qua...

    journal_title:Surgery today

    pub_type: 杂志文章,评审

    doi:10.1007/s00595-019-1763-y

    authors: Hoshino N,Sakamoto T,Hida K,Sakai Y

    更新日期:2019-07-01 00:00:00

  • Clinical characteristics of 12 cases of appendiceal diverticulitis: a comparison with 378 cases of acute appendicitis.

    abstract:PURPOSE:Previous authors have suggested that a diverticulum of the vermiform appendix has a higher risk of perforation than acute appendicitis. Therefore, this study compared appendiceal diverticulitis with acute appendicitis to explain the characteristics of appendiceal diverticulitis. METHODS:Data for this study cam...

    journal_title:Surgery today

    pub_type: 杂志文章

    doi:10.1007/s00595-012-0152-6

    authors: Yamana I,Kawamoto S,Inada K,Nagao S,Yoshida T,Yamashita Y

    更新日期:2012-04-01 00:00:00

  • Laparoscopic versus open colectomy for TNM stage III colon cancer: results of a prospective multicenter study in Italy.

    abstract:BACKGROUND AND PURPOSE:There is still debate about the practicality of performing laparoscopic colectomy instead of open colectomy for patients with curable cancer, although laparoscopic surgery is now being performed even for patients with advanced colon cancer. We compared the long-term results of laparoscopic versus...

    journal_title:Surgery today

    pub_type: 临床试验,杂志文章,多中心研究

    doi:10.1007/s00595-012-0292-8

    authors: Guerrieri M,Campagnacci R,De Sanctis A,Lezoche G,Massucco P,Summa M,Gesuita R,Capussotti L,Spinoglio G,Lezoche E

    更新日期:2012-11-01 00:00:00

  • Coexisting aortocolic and aortovesical fistulae in an abdominal aortic aneurysm: report of a case.

    abstract::Aortoenteric fistula is a rare complication in abdominal aortic aneurysms (AAA), and an aortovesical fistula is even more rare. This is a report of a case of aortocolic and aortovesical fistulae in a 64-year-old man with AAA who was treated with an aortobiiliac bypass, a primary repair of the fistulated bladder, and a...

    journal_title:Surgery today

    pub_type: 杂志文章

    doi:10.1007/s10595-002-2510-3

    authors: Kang SJ,Kim DI,Huh SH,Lee BB,Kim DK,Do YS

    更新日期:2003-01-01 00:00:00

  • Laparoscopy-assisted low anterior resection with a prolapsing technique for low rectal cancer.

    abstract::Laparoscopy-assisted low anterior resection (LAR) for low rectal cancer is a difficult procedure, presenting problems with rectal washout, selecting the appropriate distal transection line, and achieving safe anastomosis. To resolve these problems, we used a prolapsing technique to perform laparoscopy-assisted LAR. To...

    journal_title:Surgery today

    pub_type: 杂志文章

    doi:10.1007/s00595-004-2984-1

    authors: Fukunaga M,Kidokoro A,Iba T,Sugiyama K,Fukunaga T,Nagakari K,Suda M,Yoshikawa S

    更新日期:2005-01-01 00:00:00

  • Impact of Surgical Infection Society/Infectious Disease Society of America-recommended antibiotics on postoperative intra-abdominal abscess with image-guided percutaneous abscess drainage following gastrointestinal surgery.

    abstract:PURPOSE:The aims of this study were to reveal how using the antibiotics recommended by the 2010 Surgical Infection Society (SIS) and Infectious Disease Society of America (IDSA) guidelines can affect the therapeutic outcomes. METHODS:We reviewed the cases of 53 patients with a postoperative intra-abdominal abscess wit...

    journal_title:Surgery today

    pub_type: 杂志文章

    doi:10.1007/s00595-014-1047-5

    authors: Okita Y,Kobayashi M,Araki T,Fujikawa H,Koike Y,Otake K,Mikihiro I,Toiyama Y,Ohi M,Tanaka K,Inoue Y,Uchida K,Mohri Y,Yamakado K,Kusunoki M

    更新日期:2015-08-01 00:00:00

  • Concomitant pulmonary carcinoma and abdominal aortic aneurysm: therapeutic strategies.

    abstract:PURPOSE:A diagnosis of concomitant pulmonary carcinoma and abdominal aortic aneurysm is rare (<1% of treated cases). However, such an association makes the therapeutic decisions critical, especially regarding the priority and timing of treatment. This article reports on our experience of 14 cases of concomitant pulmona...

    journal_title:Surgery today

    pub_type: 杂志文章

    doi:10.1007/s00595-006-3672-0

    authors: Borzellino G,Giovinazzo F,Minicozzi AM,Dusi R,Politi L,Veraldi GF

    更新日期:2008-01-01 00:00:00

  • Predictors of nodal upstaging in patients with cT1-3N0 non-small cell lung cancer (NSCLC): results from the Italian VATS Group Registry.

    abstract:PURPOSE:Accurate staging of early non-small cell lung cancer is fundamental for selecting the best treatment. The aim of this study was to identify risk factors for nodal upstaging after video-assisted thoracoscopic lobectomy for clinical T1-3N0 tumors. METHODS:From 2014 to 2017, 3276 thoracoscopic lobectomies were re...

    journal_title:Surgery today

    pub_type: 杂志文章

    doi:10.1007/s00595-019-01939-x

    authors: Marulli G,Faccioli E,Mammana M,Nicotra S,Comacchio G,Verderi E,De Palma A,Rea F,Italian VATS Group.

    更新日期:2020-07-01 00:00:00

  • Surgical treatment of hepatocellular carcinoma.

    abstract::Local tumor control is still the most important consideration in the treatment of hepatocellular carcinoma (HCC). Surgical treatments, including liver resection and liver transplantation are, and will remain, the first-line therapeutic strategies for local control in patients with primary HCC. Although aggressive live...

    journal_title:Surgery today

    pub_type: 杂志文章,评审

    doi:10.1007/s00595-008-4024-z

    authors: Hasegawa K,Kokudo N

    更新日期:2009-01-01 00:00:00

  • Clinical and pathological features of intracystic papillary carcinoma of the breast.

    abstract:PURPOSE:To evaluate the clinicopathological features of intracystic papillary carcinoma (ICPC), which have not been established given its rarity and lack of standard diagnostic criteria. METHODS:We reviewed the clinicopathological findings and treatment outcomes of 14 patients with ICPC diagnosed between 2002 and 2006...

    journal_title:Surgery today

    pub_type: 杂志文章

    doi:10.1007/s00595-008-3792-9

    authors: Akagi T,Kinoshita T,Shien T,Hojo T,Akashi-Tanaka S,Murata Y

    更新日期:2009-01-01 00:00:00