Monoclonal antibodies: innovations in diagnosis and therapy.

Abstract:

OBJECTIVE:To provide a review of the use of monoclonal antibodies (MAbs) for diagnosis and therapy, the obstacles affecting their usefulness, and nursing considerations unique to MAb-based treatments. DATA SOURCES:Research studies, review articles, and book chapters pertaining to MAbs in cancer diagnosis and therapy. CONCLUSIONS:Recent clinical trials have shown the potential of MAbs as diagnostic and therapeutic tools in cancer. MAbs may be used alone or conjugated with drugs, radionuclides, and toxins; however numerous obstacles limit their effectiveness. IMPLICATIONS FOR NURSING PRACTICE:Oncology nurses caring for patients receiving MAb-based therapies play an important role in the implementation of the patient's regimen. Hypersensitivity reactions, constitutional symptoms, and serum sickness are toxic effects that require monitoring and patient education.

journal_name

Semin Oncol Nurs

authors

Baquiran DC,Dantis L,McKerrow J

doi

10.1016/s0749-2081(96)80007-6

subject

Has Abstract

pub_date

1996-05-01 00:00:00

pages

130-41

issue

2

eissn

0749-2081

issn

1878-3449

pii

S0749-2081(96)80007-6

journal_volume

12

pub_type

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