Abstract：
:Unconsummated marriage (UM) is the failure to perform successful sexual intercourse at the beginning of the marriage. Vaginismus has been traditionally reported as the leading cause. ED is also a leading cause for UM. This appears to be a significant problem in the conservative middle-Eastern societies and in the developing countries, where couples are strongly prevented by religious rules and cultural taboos from sexual experiences before wedding. One could think that according to major sexual freedom and information, in Western countries UM is now disappearing, but the number of observed cases by the authors in 2008-2012 was relevant. The aim of this study is to compare the literature data from non-Western countries with the features of UM in Western ones, focusing on cases observed by the authors, and to verify whether the etiology of UM proposed in the '70s is still relevant, outlining any changes that occur in current reality. In our series, traditional appearance of UM is no more effective, while the role of man is undervalued, because of his frailty, lack of self-confidence and ignorance, expressing a social and cultural change of man's role in the couple.
journal_name
Int J Impot Resjournal_title
International journal of impotence researchauthors
Michetti PM,Silvaggi M,Fabrizi A,Tartaglia N,Rossi R,Simonelli Cdoi
10.1038/ijir.2013.24subject
Has Abstractpub_date
2014-01-01 00:00:00pages
28-30issue
1eissn
0955-9930issn
1476-5489pii
ijir201324journal_volume
26pub_type
杂志文章abstract：:The objective was to investigate the cellular effect and action mechanism of Artemisia capillaris extract (ACE) and its component, scopoletin, on penile corpus cavernosum smooth muscle (PCCSM). In vitro study with PCCSM, the precontracted PCCSM with phenylephrine was treated with ACE or scopoletin. Cyclic nucleotides ...
journal_title：International journal of impotence research
pub_type： 杂志文章
doi：10.1038/ijir.2015.23
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abstract：:Adlay (Coix lachryma-jobi L. var. ma-yuen Stapf.) has long been used as a traditional Chinese medicine for dysfunctions of the endocrine system and inflammation conditions. However, the effect of adlay seed on the endocrine system has not yet been reported. In the present study, the effects and the mechanisms of metha...
journal_title：International journal of impotence research
pub_type： 杂志文章
doi：10.1038/sj.ijir.3901405
更新日期：2006-05-01 00:00:00
abstract：:Erectile dysfunction (ED), generally associated with reduced sexual desire and sometimes with orgasmic or ejaculatory dysfunction, is the major revealing symptom of hyperprolactinemia (HPRL) in men, a condition that should not be neglected since many cases result from pituitary tumors, likely to result in serious comp...
journal_title：International journal of impotence research
pub_type： 杂志文章,评审
doi：10.1038/sj.ijir.3901043
更新日期：2003-10-01 00:00:00
abstract：:Erectile dysfunction (ED) is defined as the inability to attain and maintain erection of the penis sufficient to permit satisfactory sexual activity. ED most commonly affects men from 40 years of age with a clear age-associated increase in prevalence. The condition may have significant negative impact on quality of li...
journal_title：International journal of impotence research
pub_type： 杂志文章,评审
doi：10.1038/s41443-019-0132-0
更新日期：2019-05-01 00:00:00
abstract：:This study was aimed to identify characteristics of ED patients who discontinued PDE5i despite successful intercourse. Data were collected using a questionnaire from 34 urologic clinics regardless of the effect (success or failure) of PDE5i treatment by visiting the clinics (717), e-mail (64) or post (101) for 882 ED ...
journal_title：International journal of impotence research
pub_type： 杂志文章
doi：10.1038/ijir.2013.41
更新日期：2014-05-01 00:00:00
abstract：:This discussion summarizes the potential differences in physiologically and pharmacologically induced erections and highlights the possible differences in the pathways facilitated by oral versus intracavernosal agents in penile erection. Oral agents act in conjunction with sexual stimulation either increasing corporal...
journal_title：International journal of impotence research
pub_type： 杂志文章
doi：
更新日期：2000-03-01 00:00:00
abstract：:Although several studies on toxic effect of aspartame metabolite have been studied, controversial reports over the use of aspartame owing to the fact that it releases methanol as one of its metabolite during metabolism exist. This present study is proposed to investigate whether aspartame (40 mg kg-1 b.wt) administrat...
journal_title：International journal of impotence research
pub_type： 杂志文章
doi：10.1038/ijir.2017.17
更新日期：2017-07-01 00:00:00
abstract：:Currently available agents for erectile dysfunction (ED) share the same mechanism of action and pharmacologic properties. Therefore, they share the same limitations, including a principal focus on erection as an end-organ process. One of the relatively unexplored areas of research has been the potential for centrally ...
journal_title：International journal of impotence research
pub_type： 杂志文章,评审
doi：10.1038/ijir.2008.18
更新日期：2008-07-01 00:00:00
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journal_title：International journal of impotence research
pub_type： 杂志文章
doi：10.1038/ijir.2014.23
更新日期：2015-01-01 00:00:00
abstract：:Apomorphine SL (TAP Holdings, Deerfield, IL) is a centrally acting treatment for erectile dysfunction (ED) that has been undergoing phase III trials. Over 3000 men have received apomorphine SL and over 75,000 doses have been taken. In the first three phase III parallel arm cross-over double-blind studies 854 patients ...
journal_title：International journal of impotence research
pub_type： 杂志文章,meta分析
doi：10.1038/sj.ijir.3900581
更新日期：2000-10-01 00:00:00
abstract：:The present study provides a review of stem cell therapy as a treatment of erectile dysfunction from peer-reviewed human and animal trials. A literature search was conducted in PubMed-Medline, Scopus, Embase, and Cochrane databases. Tweenty-three animal studies and seven human studies in the period from 1st of January...
journal_title：International journal of impotence research
pub_type： 杂志文章,评审
doi：10.1038/s41443-020-00406-3
更新日期：2021-01-15 00:00:00
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journal_title：International journal of impotence research
pub_type： 杂志文章,评审
doi：10.1038/sj.ijir.3900994
更新日期：2003-04-01 00:00:00
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journal_title：International journal of impotence research
pub_type： 杂志文章,评审
doi：10.1038/ijir.2011.45
更新日期：2012-01-01 00:00:00
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journal_title：International journal of impotence research
pub_type： 临床试验,杂志文章
doi：10.1038/sj.ijir.3901618
更新日期：2008-03-01 00:00:00
abstract：:In a prospective, placebo-controlled, one group crossover design study, we tested whether adding programmed intracavernous PGE1 injections (IC-PGE1) can improve the effectiveness of sildenafil in erectile dysfunction (ED) patients unresponsive to monotherapy with this drug. In all, 40 ED patients who had experienced u...
journal_title：International journal of impotence research
pub_type： 临床试验,杂志文章
doi：10.1038/sj.ijir.3901290
更新日期：2005-07-01 00:00:00
abstract：:We describe a case of gunshot wound to the corpora cavernosa caused by a low-velocity bullet in a 43-year-old man. He volunteered that his lover's husband shot him with a handgun. The bullet had penetrated the right gluteal region with no exit wound causing a right corpus cavernosum lesion. A penile colour-duplex dopp...
journal_title：International journal of impotence research
pub_type： 杂志文章
doi：10.1038/sj.ijir.3901472
更新日期：2006-11-01 00:00:00
abstract：:The aim of our study was to describe the impact of mid-urethral sling procedure for the treatment of stress urinary incontinence (SUI) on female sexual function. We used PubMed (updated March 2015) to conduct a literature electronic search that included peer-reviewed English language articles. We analyzed the studies ...
journal_title：International journal of impotence research
pub_type： 杂志文章,评审
doi：10.1038/ijir.2016.16
更新日期：2016-07-01 00:00:00
abstract：:Both RigiScan and the Snap Gauge band devices are used to objectively measure penile rigidity. The Snap Gauge band is the more simple and inexpensive of the two techniques. We investigated the correlation between the results obtained by both devices in order to evaluate whether the Snap Gauge band could be employed as...
journal_title：International journal of impotence research
pub_type： 临床试验,杂志文章
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更新日期：1999-12-01 00:00:00
abstract：:Considering the presence of dopaminergic receptors in the lumbosacral spinal cord, we tested whether apomorphine could exert a proerectile effect by acting at the spinal level. Intracavernous (ICP) and blood pressures (BP) were measured in anesthetized rats. ICP rises were quantified (duration, percentage of ICPmaximu...
journal_title：International journal of impotence research
pub_type： 杂志文章
doi：10.1038/sj.ijir.3900654
更新日期：2001-04-01 00:00:00
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journal_title：International journal of impotence research
pub_type： 杂志文章
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journal_title：International journal of impotence research
pub_type： 杂志文章
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更新日期：2017-05-01 00:00:00
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journal_title：International journal of impotence research
pub_type： 杂志文章
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更新日期：2014-03-01 00:00:00
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journal_title：International journal of impotence research
pub_type： 杂志文章
doi：10.1038/sj.ijir.3901335
更新日期：2005-07-01 00:00:00
abstract：:To date, no effective medical approach for the treatment of erectile dysfunction (ED) secondary to ischemic priapism (IP) has been described. The aim of this study was to evaluate the anti-inflammatory, antifibrotic, and antioxidant effects of pirfenidone (PFD) on cavernosal tissue in a rat model of IP. Forty-eight ma...
journal_title：International journal of impotence research
pub_type： 杂志文章
doi：10.1038/s41443-019-0152-9
更新日期：2020-03-01 00:00:00
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journal_title：International journal of impotence research
pub_type： 杂志文章
doi：
更新日期：1995-09-01 00:00:00
abstract：:The imbalance between vasoconstrictors and vasodilators may play an important role in the pathogenesis of erectile dysfunction (ED). A total of 36 patients with ED, organogenic [diabetic (n=12) and nondiabetic (n=12)] and psychogenic (n=12) etiology, and 12 healthy adult men as controls were included. The levels of en...
journal_title：International journal of impotence research
pub_type： 杂志文章
doi：10.1038/sj.ijir.3901059
更新日期：2003-12-01 00:00:00
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journal_title：International journal of impotence research
pub_type： 杂志文章
doi：10.1038/sj.ijir.3901373
更新日期：2006-03-01 00:00:00
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journal_title：International journal of impotence research
pub_type： 杂志文章
doi：10.1038/sj.ijir.3900856
更新日期：2002-08-01 00:00:00
abstract：:Early pharmacological prophylaxis has been reported to increase the return of spontaneous erections following radical prostatectomy (RP). In this study, we evaluated the role of intracavernosal alprostadil (PGE1) combined with sildenafil in stimulating early recovery of spontaneous erections following RP. In this pros...
journal_title：International journal of impotence research
pub_type： 杂志文章
doi：10.1038/sj.ijir.3901448
更新日期：2006-09-01 00:00:00
abstract：:There is evidence that emotional intimacy can buffer the distress associated with sexual difficulties. Considering that older adults are at an increased risk of chronic illness, many of which (including their medical treatment) can impact their sexual well-being, the link between intimacy and sexual distress may be pa...
journal_title：International journal of impotence research
pub_type： 杂志文章
doi：10.1038/s41443-019-0214-z
更新日期：2020-09-01 00:00:00
