Abstract：
OBJECTIVES:Intracavernosal injection of vasodilating agents has been a mainstay in the treatment of erectile dysfunction. Recently, a transurethral delivery system (MUSE) for alprostadil (prostaglandin E1) was introduced as an alternative form of pharmacotherapy. METHODS:One hundred consecutive patients with erectile dysfunction were treated with MUSE in doses ranging from 125 to 1000 micrograms and their erections were observed in the clinical setting. All patients had previous intracavernosal injections of combination pharmacotherapy (papavarine, Regitine, and/or prostaglandin E1). RESULTS:Of these 100 patients that used MUSE, only 7% had well-sustained, rigid erections while 30% had full erections but with partial rigidity. The remaining 63% of patients did not achieve erections that they thought were adequate for penetration. Penile and/or perineal pain occurred in 24% of patients, 3% had a syncopal episode, and 3% experienced urethral bleeding. One patient had priapism that required drainage. Using intracavernosal injections, 49% had sustained rigid erections, 40% had full erections with partial rigidity, and 11% did not have a response satisfactory for penetration. CONCLUSIONS:These data suggest that intracavernosal injections appear to be more effective than MUSE in achieving a rigid erection in men with erectile dysfunction.
journal_name
Urologyjournal_title
Urologyauthors
Werthman P,Rajfer Jdoi
10.1016/S0090-4295(97)00448-2subject
Has Abstractpub_date
1997-11-01 00:00:00pages
809-11issue
5eissn
0090-4295issn
1527-9995pii
S0090-4295(97)00448-2journal_volume
50pub_type
临床试验,杂志文章相关文献
UROLOGY文献大全abstract：OBJECTIVE:To investigate the impact of cystectomy for the treatment of refractory benign disease secondary to radiation therapy on the health-related quality of life (HRQOL). METHODS:A retrospective review was performed on patients undergoing cystectomy for the management of treatment-refractory disease secondary to r...
journal_title：Urology
pub_type： 杂志文章
doi：10.1016/j.urology.2014.08.047
更新日期：2015-02-01 00:00:00
abstract：OBJECTIVES:To review our initial experience with transvesicoscopic ureteral reimplantation (TVUR) in children with vesicoureteral reflux and to evaluate the learning curve for the feasibility and reproducibility of TVUR. METHODS:TVUR was performed in 28 consecutive patients with a mean age of 6.0 years. Cohen's classi...
journal_title：Urology
pub_type： 杂志文章
doi：10.1016/j.urology.2010.11.023
更新日期：2011-06-01 00:00:00
abstract：OBJECTIVES:To address the incidence of local recurrence and port site metastasis in patients who underwent laparoscopic radical nephroureterectomy (RNU) for upper tract transitional cell carcinoma (TCC). METHODS:Between August 1993 and February 2006 116 laparoscopic RNU were performed in 115 patients at our institutio...
journal_title：Urology
pub_type： 杂志文章
doi：10.1016/j.urology.2007.07.027
更新日期：2007-11-01 00:00:00
abstract：:We report the case of a 56-year-old man who in a motor vehicle collision developed a pelvic fracture and complete urethra rupture. Sudden onset of intermittent severe urethral bleeding occurred and it led to life-threatening blood pressure drop and dyspnea. An angiography of internal iliac artery showed a pseudoaneury...
journal_title：Urology
pub_type： 杂志文章
doi：10.1016/j.urology.2013.08.016
更新日期：2013-12-01 00:00:00
abstract：OBJECTIVE:To evaluate clinical and patient-reported urinary and sexual outcomes after a long-segment stricture repair using the 1-sided urethral dissection, penile invagination, and dorsal buccal mucosa graft onlay technique described by Kulkarni et al. METHODS:Patients from 4 institutions after single-stage repairs f...
journal_title：Urology
pub_type： 杂志文章,多中心研究
doi：10.1016/j.urology.2017.08.029
更新日期：2018-01-01 00:00:00
abstract：OBJECTIVES:To estimate the relationship between serum prostate-specific antigen (PSA) and prostatic epithelial volume, a new simple method for measuring epithelial volume was developed and its efficacy evaluated in patients with benign prostatic hyperplasia. METHODS:Between March 1998 and June 2001, 122 patients witho...
journal_title：Urology
pub_type： 杂志文章
doi：10.1016/s0090-4295(02)02159-3
更新日期：2003-02-01 00:00:00
abstract：:Closed suprapubic cystostomy is an expeditious procedure for a variety of clinical conditions requiring urinary drainage. Its benignity is reflected by a low complication rate of 1.6 per cent and no deaths in this series of 244 consecutive patients. Nevertheless, major complications can occur if proper technique is no...
journal_title：Urology
pub_type： 杂志文章
doi：10.1016/0090-4295(78)90197-8
更新日期：1978-01-01 00:00:00
abstract：OBJECTIVE:Up to 10% of patients who have undergone the Bricker ileal conduit urinary diversion may develop ureteroileal anastomotic complications that are more frequently associated with the left side ureter. We have therefore modified the standard Bricker ileal conduit technique to minimize the anastomotic complicatio...
journal_title：Urology
pub_type： 杂志文章
doi：10.1016/j.urology.2011.07.001
更新日期：2011-11-01 00:00:00
abstract：:Methotrexate (MTX) has activity in transitional cell carcinoma (TCC) in man and some have suggested an advantage of high-dose methotrexate versus the standard dose in controlling tumor growth and prolonging survival. MBT-2, a poorly differentiated TCC induced by the carcinogen FANFT, is both grossly and histologically...
journal_title：Urology
pub_type： 杂志文章
doi：10.1016/0090-4295(90)80044-n
更新日期：1990-03-01 00:00:00
abstract：:Endoscopically placed inlying ureteral stents have proved useful in the conservative management of patients with ureteral obstruction, urinary fistula, and malignancy and have obviated the need for operative intervention. In high-risk symptomatic patients with widespread malignancy, internal urinary diversion offers t...
journal_title：Urology
pub_type： 杂志文章
doi：10.1016/0090-4295(79)90143-2
更新日期：1979-08-01 00:00:00
abstract：OBJECTIVES:To perform a population-based analysis of the potential staging or prognostic value (or both) of lymph node dissection (LND) in patients without nodal metastases vs no LND. In several previous reports, LND in patients with upper tract urothelial carcinoma (UTUC) treated with nephroureterectomy (NU) was assoc...
journal_title：Urology
pub_type： 杂志文章
doi：10.1016/j.urology.2009.07.1296
更新日期：2010-01-01 00:00:00
abstract：OBJECTIVES:To investigate the effectiveness and morbidity of percutaneous laser endoureterotomy in the management of ureterointestinal anastomotic strictures after radical cystectomy and urinary diversion. METHODS:Between May 1997 and August 2000, 19 percutaneous endoureterotomy incisions, including 3 repeated incisio...
journal_title：Urology
pub_type： 杂志文章
doi：10.1016/s0090-4295(01)01396-6
更新日期：2001-12-01 00:00:00
abstract：:Vas irrigation during vasectomy, to effect immediate sterility or to shorten the interval between vasectomy and sterility, has received increasing attention in recent years. A review of the literature on vas irrigation is presented. Topics discussed include the effectiveness of various irrigants and irrigation methods...
journal_title：Urology
pub_type： 杂志文章,评审
doi：10.1016/0090-4295(79)90173-0
更新日期：1979-11-01 00:00:00
abstract：:A case of bilateral metachronous renal cell carcinoma with gallbladder and pancreatic metastases, presenting with hematobilia and anemia is presented. The presentation of metastatic renal cell carcinoma with hematobilia and anemia is previously unreported. This case illustrates (1) the occasionally very long interval ...
journal_title：Urology
pub_type： 杂志文章
doi：10.1016/s0090-4295(05)80084-6
更新日期：1991-08-01 00:00:00
abstract：:Urodynamics, although not diagnostic of IC, are useful in the differential diagnosis of painful voiding disorders and provide a convenient way to quantitate response to therapy. They may prove useful as prognostic indicators of response to treatment and are of value in those patients in whom surgery is considered. Our...
journal_title：Urology
pub_type： 杂志文章
doi：
更新日期：1987-04-01 00:00:00
abstract：OBJECTIVES:To correlate urologists' impressions of the tumor grade of upper tract tumors at ureteroscopy with the histologic findings after biopsy or resection. METHODS:A retrospective review of all patients who underwent diagnostic or therapeutic ureteroscopy for upper tract transitional cell carcinoma (TCC) between ...
journal_title：Urology
pub_type： 杂志文章
doi：10.1016/j.urology.2003.10.076
更新日期：2004-04-01 00:00:00
abstract：:Long-term analyses of the UroLume Endoprosthesis have shown conflicting results with regard to efficacy and restricture rates. The best management of recurrent urethra stricture disease at the site of a previous UroLume stent is unknown. We describe a previously unreported technique for transperineal excision of the U...
journal_title：Urology
pub_type： 杂志文章
doi：10.1016/j.urology.2005.08.038
更新日期：2006-02-01 00:00:00
abstract：OBJECTIVES:Subepithelial hydroxyapatite calcification of renal papilla is thought to be involved in the formation of calcium oxalate monohydrate (COM) papillary calculi. To assess the mechanism of formation, we sought to correlate the fine structure of papillary renal calculi with specific pathophysiologic conditions a...
journal_title：Urology
pub_type： 杂志文章
doi：10.1016/j.urology.2010.02.022
更新日期：2010-12-01 00:00:00
abstract：OBJECTIVES:To evaluate the financial implications of how the costs of new minimally invasive surgery such as laparoscopic robotic prostatectomy (LRP) and cryosurgical ablation of the prostate (CAP) technologies compare with those of conventional surgery. METHODS:From January 2002 to July 2005, 452 consecutive patients...
journal_title：Urology
pub_type： 杂志文章
doi：10.1016/j.urology.2006.10.025
更新日期：2007-02-01 00:00:00
abstract：OBJECTIVE:To evaluate the California Cancer Registry in order to define nonclear cell renal cell cancer (RCC) clinical features and outcomes, identify prognostic variables, and generate hypotheses for further study. METHODS:Patients with invasive RCC tumors in the California Cancer Registry from 1998 to 2009 (n = 38,2...
journal_title：Urology
pub_type： 杂志文章
doi：10.1016/j.urology.2013.07.020
更新日期：2013-10-01 00:00:00
abstract：OBJECTIVE:To characterize the standard physical, chemical, and microscopic characteristics of urine in patients with noncomplicated orthotopic ileal neobladders. MATERIALS AND METHODS:This is a prospective study that included 100 male patients who underwent radical cystectomy and ileal neobladder between 1993 and 2013...
journal_title：Urology
pub_type： 杂志文章
doi：10.1016/j.urology.2016.06.047
更新日期：2016-10-01 00:00:00
abstract：:We report a case of symptomatic hypercalcemia in a patient with muscle-invasive, resectable squamous cell carcinoma of the bladder. Serum parathyroid hormone was consistent with secretion of parathyroid hormone-related protein. After radical cystoprostatectomy, calcium levels returned to normal. Patients with squamous...
journal_title：Urology
pub_type： 杂志文章
doi：10.1016/s0090-4295(97)00638-9
更新日期：1998-03-01 00:00:00
abstract：:Twenty-five patients underwent audiovisual sexual stimulation (AVSS) after pharmacologically-induced erection. Grade of erection and cavernosal blood flow were assessed after intracorporeal (IC) injection of TRI-MIX or prostaglandin E1, and then after AVSS, using pulsed Doppler ultrasonography (PDUS). After IC injecti...
journal_title：Urology
pub_type： 杂志文章
doi：10.1016/0090-4295(93)90502-2
更新日期：1993-05-01 00:00:00
abstract：OBJECTIVE:To present the results of a new technique for abdominoplasty in patients with the Prune Belly syndrome (PBS). METHODS:Since 1985, 46 children with PBS underwent surgical treatment that included urinary tract reconstruction (UTR), orchidopexy, and abdominoplasty. In 41 patients, we performed the abdominoplast...
journal_title：Urology
pub_type： 杂志文章
doi：10.1016/j.urology.2013.09.031
更新日期：2014-02-01 00:00:00
abstract：:Four patients with protracted benign hematuria underwent silver nitrate instillation of the upper collecting system. The doses varied from 10 ml. of 0.25 per cent silver nitrate to 14 ml. of 1 per cent silver nitrate. In all 4 cases the hematuria resolved within four days without significant complications. At follow-u...
journal_title：Urology
pub_type： 杂志文章
doi：10.1016/0090-4295(81)90384-8
更新日期：1981-10-01 00:00:00
abstract：OBJECTIVES:To examine the long-term efficacy of Prostatic Urethral Lift (PUL) for treating men, with or without an obstructive median lobe (OML), who suffer from lower urinary tract symptoms (LUTS) attributed to benign prostatic hyperplasia (BPH). MATERIALS AND METHODS:A retrospective review was performed on all conse...
journal_title：Urology
pub_type： 杂志文章
doi：10.1016/j.urology.2021.01.025
更新日期：2021-01-22 00:00:00
abstract：OBJECTIVE:To evaluate the functional and morphologic outcome after open pyeloplasty for ureteropelvic junction obstruction (UPJO) in ectopic pelvic kidneys. MATERIALS AND METHODS:A retrospective review of all patients who underwent open pyeloplasty in ectopic pelvic kidneys was conducted. Records were evaluated with r...
journal_title：Urology
pub_type： 杂志文章
doi：10.1016/j.urology.2012.07.057
更新日期：2012-12-01 00:00:00
abstract：OBJECTIVES:To compare the outcomes of those patients who underwent laparoscopic versus open cytoreductive nephrectomy. Cytoreductive nephrectomy before systemic therapy has been shown to offer a survival advantage compared with systemic therapy alone for metastatic renal cell carcinoma. METHODS:We reviewed the outcome...
journal_title：Urology
pub_type： 杂志文章
doi：10.1016/j.urology.2004.06.052
更新日期：2004-11-01 00:00:00
abstract：:The charts of all patients receiving radical surgery and radiation therapy for cancer localized to the prostate in the years 1950 to 1977 in the State of Connecticut were reviewed. Long-term survival rates at ten and fifteen years were considerably better in those patients treated with radical surgery. ...
journal_title：Urology
pub_type： 杂志文章
doi：10.1016/0090-4295(85)90483-2
更新日期：1985-04-01 00:00:00
abstract：:A histologic study of the vas ends was carried out in 21 patients undergoing vasovasostomy. All had undergone prior vasectomy by the same surgeon, with a technique identical except for the type of cautery used to seal the vas ends. A superior sealing of the vas, as shown by fewer cases of vasitis nodosa and spermatic ...
journal_title：Urology
pub_type： 杂志文章
doi：10.1016/0090-4295(92)90468-c
更新日期：1992-11-01 00:00:00
