[Comparative assessment of treatment efficacy with lamotrigine (Lamictal) together with valproate and/or carbamazepine in patients with refractory epilepsy].

Abstract:

:For the study 17 patients aged 26-55 years were qualified after ineffective treatment with carbamazepine and/or valproate for simple partial, complex partial or secondary generalized seizures. The criterion of resistance to treatment was the occurrence of four or more seizures monthly. The treatment with lamotrigine was successful in 9 (52%) cases, with reduction of seizures by at least 50%. In 2 cases the seizure activity in EEG became normal. In 8 cases the addition of lamotrigine was ineffective and the drug was discontinued (in one case due to allergic rash and in one the cause was toxic hepatocellular damage).

journal_name

Neurol Neurochir Pol

authors

Wierzba W,Wajgt A

subject

Has Abstract

pub_date

1997-11-01 00:00:00

pages

1133-46

issue

6

eissn

0028-3843

issn

1897-4260

journal_volume

31

pub_type

临床试验,杂志文章
  • [A case of Behcet's syndrome].

    abstract::The author reports a case of Behcet's disease in a girl aged 18 years with recurrent lesions of the oral and vulvar mucosa, eyes and nervous system. The disease had a recurrent character with a tendency for progressing deterioration. Treatment was unsuccessful and the patient died. ...

    journal_title:Neurologia i neurochirurgia polska

    pub_type: 杂志文章

    doi:

    authors: Maślanka S

    更新日期:1985-01-01 00:00:00

  • [Usefulness of epidurography in the diagnosis of pathological changes in the vertebral canal].

    abstract::The authors evaluated 60 epidurographies performed in patients with suspected compressing lesions in the vertebral canal. It was demonstrated that epidurography may be a useful method for diagnosis of pathological conditions in the vertebral canal, particularly in its thoracolumbar part. In many cases this method is s...

    journal_title:Neurologia i neurochirurgia polska

    pub_type: 杂志文章

    doi:

    authors: Zarski S,Bowkiewicz J,Pawlik-Dobrowolska H,Styczyński T

    更新日期:1978-03-01 00:00:00

  • [Hydrocortisone in the treatment of painful syndromes of the cervical spine].

    abstract::The authors used hydrocortisone POLFA injecting it paravertebrally in painful syndromes of the cervical spine. The clinical material comprised 50 patients divided into groups A and B of 25 patients each. In both groups typical anti-inflammatory and analgesic agents and muscle relaxants were given and physiotherapy was...

    journal_title:Neurologia i neurochirurgia polska

    pub_type: 杂志文章

    doi:

    authors: Eljasz L,Krazysztoń-Przekop T

    更新日期:1976-09-01 00:00:00

  • [Open multicenter study of the effectiveness and safety of gabitril in epileptic patients with partial seizures].

    abstract::The paper presents the results obtained by 53 investigators implementing the first Polish multicentre study of the effectiveness and safety of tiagabine (Gabitril). The study included 81 patients with refractory epilepsy with partial seizures. The duration of the study was 16 weeks. For the initial 6 weeks, Gabitril w...

    journal_title:Neurologia i neurochirurgia polska

    pub_type: 临床试验,杂志文章,多中心研究

    doi:

    authors: Czapiński P,Jedrzejczak J,Kozik A,Sobaniec W,Wendorff J,Grygolec P

    更新日期:2000-01-01 00:00:00

  • [Evaluation of the mental state of children with early-childhood onset of epilepsy treated between 1977 and 1981 (preliminary report)].

    abstract::From a group of 248 cases of epilepsy observed in the last five years 69 (28%) children, 32 boys and 37 girls, were isolated (aged from several months to 14 years) in whom the first epileptic seizures appeared at the age of 3 years or less. The subgroups were subjected to detailed psychiatric-psychological analysis fo...

    journal_title:Neurologia i neurochirurgia polska

    pub_type: 杂志文章

    doi:

    authors: Popielarska M,Popielarska A,Golczyk-Wojnar A,Komender J,Tomaszewicz-Libudzic C,Fabisiak A

    更新日期:1984-11-01 00:00:00

  • [Rheographic studies in the diagnosis of vertebrobasilar syndromes].

    abstract::The authors report the results of investigations of 33 healthy subjects and 33 patients with manifestations of intracranial circulatory disturbances in the vascularization area of the vertebrobasilar system. Type II rheography was used. All curves from the vertebral, vertebromastoid and frontomastoid leads were averag...

    journal_title:Neurologia i neurochirurgia polska

    pub_type: 杂志文章

    doi:

    authors: Jura E,Zareba A,Laskowska W,Zukowski A

    更新日期:1982-07-01 00:00:00

  • [Clinical and differential diagnosis of multi-infarct dementia and Alzheimer's disease].

    abstract::Multi-infarct dementia (MID) and dementia of the Alzheimer type (DAT) are the main syndromes in the elderly. This study aims at evaluating the possible differentiation of these syndromes on a clinical basis. The patient population consisted of demented patients hospitalized during the period April 1, 1988-September 30...

    journal_title:Neurologia i neurochirurgia polska

    pub_type: 杂志文章

    doi:

    authors: Jura E

    更新日期:1992-01-01 00:00:00

  • WITHDRAWN: Evidence for a relatively high proportion of DM2 mutations in a large group of Polish patients.

    abstract::The Publisher regrets that this article is an accidental duplication of an article that has already been published, 10.1016/j.pjnns.2018.02.008. The duplicate article has therefore been withdrawn. The full Elsevier Policy on Article Withdrawal can be found at https://www.elsevier.com/about/our-business/policies/articl...

    journal_title:Neurologia i neurochirurgia polska

    pub_type: 杂志文章

    doi:10.1016/j.pjnns.2018.04.004

    authors: Sulek A,Lusakowska A,Krysa W,Rajkiewicz M,Kaminska A,Nojszewska M,Kostera-Pruszczyk A,Zdzienicka E,Kubalska J,Rakowicz M,Szirkowiec W,Kwiecinski H,Zaremba J

    更新日期:2018-05-17 00:00:00

  • [Ectodermal method of Ryodorak--an attempt at clinical measurement for evaluation of physiotherapy effects in patients with low back pain].

    abstract::In the group of 132 patients with diagnosed pseudoradicular pain syndrome (57 subjects) or evident sciatic neuralgia (75 subjects) besides clinical and radiological examination, additional skin electro-conduction evaluation, being the sympathetic system activity exponent, was performed. Diagnostic part of empiric meth...

    journal_title:Neurologia i neurochirurgia polska

    pub_type: 临床试验,杂志文章

    doi:

    authors: Zytkowski A

    更新日期:1999-01-01 00:00:00

  • [Klein-Levin syndrome (case report)].

    abstract::The authors observed the syndrome in a 17-year-old boy weighing 86 kg and training weight-lifting. During between 10 and 20 months he had periods of physiological sleep lasting on the average 7 days, with voracious appetite and dysphoris. In the EEG tracings corresponding to physiological sleep were observed during th...

    journal_title:Neurologia i neurochirurgia polska

    pub_type: 杂志文章

    doi:

    authors: Nowak S,Błaszczyk B

    更新日期:1984-03-01 00:00:00

  • [Perseverance tendency in patients with generalized convulsive seizures and with partial seizures with complex symptoms].

    abstract::The intensity of perseveration was tested in 70 patients with generalized convulsive seizures and with partial seizures of complex symptomatology, and in 37 subjects without central nervous system diseases (controls). The results suggest that the tendency for perseveration is a feature occurring not only in epilepsy b...

    journal_title:Neurologia i neurochirurgia polska

    pub_type: 杂志文章

    doi:

    authors: Florek M,Bittner-Manicka M

    更新日期:1980-01-01 00:00:00

  • Spinal tuberculosis with severe neurological symptoms as a complication of intravesical BCG therapy for carcinoma of the bladder.

    abstract:INTRODUCTION:Non-invasive bladder cancer is effectively treated with intravesical BCG therapy. The administration of the BCG vaccine is to destroy the neoplastic lesion or prevent further recurrences. The activity of the vaccine involves boosting the immune system through the stimulation of the inflammation in the blad...

    journal_title:Neurologia i neurochirurgia polska

    pub_type: 杂志文章

    doi:10.1016/j.pjnns.2015.12.003

    authors: Białecki J,Nowak-Misiak M,Rąpała K,Marczyński W,Suchodolski G,Truszczyńska A

    更新日期:2016-01-01 00:00:00

  • [Differential diagnosis in multiple sclerosis: description of selected cases].

    abstract::Multiple sclerosis (MS) should be differentiated with diseases causing disseminated lesions of central nervous system or imitating clinical course of MS. Clinical course and results of laboratory investigations also immunological tests should be taken into account in differential diagnosis of MS. We present four patie...

    journal_title:Neurologia i neurochirurgia polska

    pub_type: 杂志文章

    doi:

    authors: Stelmasiak Z,Bartosik-Psujek H,Belniak-Legieć E,Gustyn T,Mitosek-Szewczyk K,Semczuk W,Krasińska-Czerlunczakiewicz H

    更新日期:2000-01-01 00:00:00

  • [Effect of cryosurgery of the thalamic nuclei on somatosensory evoked potentials].

    abstract::Somatosensory evoked potentials were recorded in two groups of patients with extrapyramidal syndromes including: 1) parkinsonian syndromes, 2) spasmodic torticollis. In the first group stereotactic lesions were produced at the borderline between VOp and Vim nuclei, and in the second group they were situated in VOa and...

    journal_title:Neurologia i neurochirurgia polska

    pub_type: 杂志文章

    doi:

    authors: Mempel E,Tarnecki R,Kuciński L,Ligezińska B,Pawłowski G

    更新日期:1984-09-01 00:00:00

  • [Effect of different stages of physiological nocturnal sleep on interseizure discharges in patients with various forms of epilepsy].

    abstract::All-night EEG records were obtained in 100 patients aged 14-48 years staying at a neurosurgical centre for various forms of focal epilepsy. In 84 cases discharges were observed during the nocturnal investigation. The morphology of the discharges depended on the phase of sleep during which they appeared. Discharges occ...

    journal_title:Neurologia i neurochirurgia polska

    pub_type: 杂志文章

    doi:

    authors: Fryze C,Bacia T

    更新日期:1983-03-01 00:00:00

  • [A case of laryngeal adductor dystonia treated with transcutaneous injections of botulinum toxin].

    abstract::We present a case of 47-year old patient with a rare form of focal dystonia restricted to laryngeal adductors with blepharospasm. Apart from typical symptoms of blepharospasm, the patient had severe problems with articulation in the form of harsh voice, frequently interrupted speech and the sound coming out with a gre...

    journal_title:Neurologia i neurochirurgia polska

    pub_type: 杂志文章

    doi:

    authors: Zielińska M,Selmaj K

    更新日期:1998-09-01 00:00:00

  • Brain tumor related-epilepsy.

    abstract:INTRODUCTION:Gliomas are commonly associated with the development of epilepsy; in some cases the two conditions share common pathogenic mechanisms and may influence each other. Brain tumor related-epilepsy (BTRE) complicates the clinical management of gliomas and can substantially affect daily life. STATE OF THE ART:T...

    journal_title:Neurologia i neurochirurgia polska

    pub_type: 杂志文章,评审

    doi:10.1016/j.pjnns.2018.06.001

    authors: Goldstein ED,Feyissa AM

    更新日期:2018-08-01 00:00:00

  • [Bilateral "crocodile tears syndrome" associated with Melkersson-Rosenthal syndrome--case report].

    abstract::We present a rare case of bilateral crocodile tears syndrome (CTS) in the course of Melkersson-Rosenthal syndrome. Melkersson-Rosenthal syndrome is characterised by a triad of recurrent orofacial swelling, relapsing facial paralysis, and fissured tongue. The classic triad is infrequent and oligosymptomatic variants ar...

    journal_title:Neurologia i neurochirurgia polska

    pub_type: 杂志文章

    doi:

    authors: Owecki MK,Kapelusiak-Pielok M,Kowal P,Kozubski W

    更新日期:2006-09-01 00:00:00

  • [Teratoma of the posterior cranial fossa].

    abstract::Two cases of posterior cranial fossa teratomas are reported. The rarity of these lesions is stressed. In the material of surgically treated cases of brain tumours from a period of 12 years in only two patients teratomas of this location were found. In adults they are extremely rare. In both cases teratoma finding duri...

    journal_title:Neurologia i neurochirurgia polska

    pub_type: 杂志文章

    doi:

    authors: Krzymiński T,Wisławski J

    更新日期:1991-05-01 00:00:00

  • [Clinico-radiological correlation and treatment of patients with absence of lumbar vertebral arch fusion].

    abstract::The authors observed 88 patients (18 women and 70 men) aged 16 to 61 years with lack of lumbar vertebral arch fusion (spina bifid occulta without spinal cord involvement). In 63 cases the clinical symptom complex was that of sciatic pains, in the remaining 25 cases no neurological defect was found. In 63 cases operati...

    journal_title:Neurologia i neurochirurgia polska

    pub_type: 杂志文章

    doi:

    authors: Gdakowicz B,Janicki W,Smereczyński A,Solecki J

    更新日期:1979-03-01 00:00:00

  • [A sixty-eight-year-old man with giant intracranial arteriovenous malformation and right-sided hemicrania -- a case report].

    abstract::Arteriovenous malformations (AVMs) are the most dangerous congenital vascular malformations. Intracranial AVMs occur in about 0.1 percent of the population and account for 1 to 2 percent of all strokes. The angioarchitecture of AVMs consists of direct arterial to venous connections without an intervening capillary net...

    journal_title:Neurologia i neurochirurgia polska

    pub_type: 杂志文章

    doi:

    authors: Bury A,Bartosz S,Dziki M,Gutkowski K

    更新日期:2005-11-01 00:00:00

  • [Multiple sclerosis: its prevalence and incidence in the population of western Poland].

    abstract::In five provinces of Western Poland the incidence and prevalence of multiple sclerosis was analyzed in patients living at the place of birth and in patients who had changed their place of residence in these provinces. The results showed that the occurrence of multiple sclerosis in geographic foci is more evident if al...

    journal_title:Neurologia i neurochirurgia polska

    pub_type: 杂志文章

    doi:

    authors: Wender M,Kowal P,Pruchnik-Grabowska D,Marcinkowski J,Hertmanowska H,Namysł I,Zielińska M

    更新日期:1987-01-01 00:00:00

  • [The image of cerebral angioma in computerized tomography].

    abstract::A case of cerebral angioma is described which was diagnosed by computer tomography and cerebral angiography. The role of computer tomography is discussed in the diagnosis of vascular intracranial anomalies. ...

    journal_title:Neurologia i neurochirurgia polska

    pub_type: 杂志文章

    doi:

    authors: Czernicki Z,Walecki J

    更新日期:1984-01-01 00:00:00

  • [Generalized choreic involuntary movements in the course of stroke: case report].

    abstract::Involuntary movements are rare ischemic stroke complication. Hemichorea, hemibalism and dystonia cases were described, especially during haemorrhage into basal ganglia and thalamus. The case of 73 years old woman is presented who was admitted to our Clinic cause of sudden choreatic involuntary movements occurrence wit...

    journal_title:Neurologia i neurochirurgia polska

    pub_type: 杂志文章

    doi:

    authors: Matusik E,Wajgt A,Zieliński T,Zych-Twardowska E

    更新日期:2003-01-01 00:00:00

  • The role of reduction in operative treatment of spondylolytic spondylolisthesis.

    abstract::Isthmic spondylolisthesis is a frequently encountered spinal disorder (3-5% of the population). The latest developments in spondylo-implantology have increased interest in operative treatment of slip. The reduction of slip, however, remains controversial and is broadly discussed. On the basis of the literature, the pa...

    journal_title:Neurologia i neurochirurgia polska

    pub_type: 杂志文章,评审

    doi:

    authors: Hakało J,Wroński J

    更新日期:2008-07-01 00:00:00

  • [Case of spontaneous intracerebral hematoma with subsequent development of post-hemorrhagic cyst].

    abstract::The authors describe a case of spontaneous intracerebral haematoma treated conservatively. After three months a large posthaemorrhagic cyst of the brain was found in the sensorimotor area. The authors suppose that in case of surgical treatment the course of the disease and its sequelae would have been much milder. The...

    journal_title:Neurologia i neurochirurgia polska

    pub_type: 杂志文章

    doi:

    authors: Marlicz M,Szecherew G,Bukowski J

    更新日期:1980-01-01 00:00:00

  • sP- and sE-selectin in stroke patients with metabolic disorders.

    abstract:BACKGROUND:Activation of platelets and endothelial cells plays an important role in the pathogenesis of atherosclerosis and thrombotic disorders. The aim of our study was to assess the relationship between the metabolic disorders and markers of platelet activity and vascular injury in patient with acute ischemic stroke...

    journal_title:Neurologia i neurochirurgia polska

    pub_type: 杂志文章

    doi:10.1016/j.pjnns.2018.08.004

    authors: Pawelczyk M,Glabiński A,Kaczorowska B,Baj Z

    更新日期:2018-01-01 00:00:00

  • [Results of multidisciplinary treatment of frontal sinus fractures].

    abstract:BACKGROUND AND PURPOSE:The aim of the study was to present the results of our management of frontal sinus fractures. MATERIALS AND METHODS:We analyzed records of 101 patients treated between 1996 and 2002, who sustained frontal sinus fractures. 7 patients were women and 94 were men. The average age of patients was 34 ...

    journal_title:Neurologia i neurochirurgia polska

    pub_type: 杂志文章

    doi:

    authors: Zapała J,Saif F,Moskała M,Krupa M

    更新日期:2006-09-01 00:00:00

  • [ABO blood groups in glioblastoma multiforme].

    abstract::The distribution of ABO blood groups was analysed statistically in 271 patients treated for glioblastoma multiforme. The control group included 500 patients treated for craniocerebral trauma. A statistically significant difference was observed in the distribution of ABO blood groups between these patient groups, with ...

    journal_title:Neurologia i neurochirurgia polska

    pub_type: 杂志文章

    doi:

    authors: Turowski K,Czochra M

    更新日期:1979-03-01 00:00:00

  • [Peripheral nerve regeneration by autografts in rats. II. Electrophysiological assessment].

    abstract::Peripheral nerves repairing using freeze-thawed skeletal muscle autografts were compared to conventional nerve grafts with respect to their electrical properties. It was found that the amplitude and distal latency of action potentials in both groups were not significantly different 3 and 6 months after the operation. ...

    journal_title:Neurologia i neurochirurgia polska

    pub_type: 杂志文章

    doi:

    authors: Król E,Drozdowski W,Skowroński J

    更新日期:1994-07-01 00:00:00