Endoscopic excision and repair of simulated bilateral cleft lips in fetal lambs.


:The use of nonpenetrating clips to accomplish wound closure as an alternative to suture in the repair of simulated cleft lips in partially exteriorized fetuses has been described previously. In this study, the fetus is approached endoscopically, and clipped (n = 8) and sutured (n = 4) intrauterine endoscopic repairs in six lambs (90- to 95-day gestation) are compared. Also used was a newly developed harmonic scalpel to create the defects in the fluid environment. Clipped repairs were nearly 10 times faster than sutured repairs (2.7 +/- 0.5 minutes compared with 24 +/- 4 minutes, respectively). Furthermore, suture incited foreign body inflammation, recruited monocytic inflammatory cells, and exhibited notable scarring. The comparison between clipped and sutured repairs extends the previous observations to the realm of endoscopy and reinforces the previous conclusions of this group that the nonpenetrating clip is more rapid and incites less inflammation than suture in fetal wound approximation and repair.


Plast Reconstr Surg


Oberg KC,Robles AE,Ducsay C,Childers B,Rasi CR,Gates DL,Kirsch WM,Hardesty RA




Has Abstract


1998-07-01 00:00:00












  • Bone formation by revascularized periosteal and bone grafts, compared with traditional bone grafts.

    abstract::Three groups of dogs were studied to compare the bone formation obtained with traditional bone grafting techniques, and that obtained with revascularized periosteum or revascularized bone grafts--all in unstressed bone. Revascularized periosteum did not produce a significant amount of bone in this unstressed model. At...

    journal_title:Plastic and reconstructive surgery

    pub_type: 杂志文章


    authors: Puckett CL,Hurvitz JS,Metzler MH,Silver D

    更新日期:1979-09-01 00:00:00

  • Anatomical study of pectoral intercostal perforators and clinical study of the pectoral intercostal perforator flap for hand reconstruction.

    abstract:BACKGROUND:The authors have used pectoral intercostal perforator flaps to reconstruct burned or injured hands by staged transfer. This flap is designed with a narrow skin pedicle that includes intercostal perforators from the fifth to eighth intercostal spaces, with a wide flap area that lies on the upper abdomen. The ...

    journal_title:Plastic and reconstructive surgery

    pub_type: 杂志文章


    authors: Oki K,Murakami M,Tanuma K,Ogawa R,Ozawa H,Hyakusoku H

    更新日期:2009-06-01 00:00:00

  • Academic Productivity, Knowledge, and Education in Plastic Surgery: The Benefit of the Clinical Research Fellow.

    abstract:BACKGROUND:Academic research productivity is limited by strenuous resident and faculty schedules but nevertheless is imperative to the growth and success of our discipline. The authors report institutional experience with their clinical research fellowship model, providing two positions per year. METHODS:A critical an...

    journal_title:Plastic and reconstructive surgery

    pub_type: 杂志文章


    authors: Carney MJ,Weissler JM,Koltz PF,Fischer JP,Wu LC,Serletti JM

    更新日期:2017-10-01 00:00:00

  • Subfascial periareolar augmentation mammaplasty.

    abstract::Subfascial placement of implants was introduced 3 years ago. Collected data reveal very promising short-term and long-term results in comparison with subglandular and subpectoral positioned implants. The clinical experiences of 69 breast augmentations in the subfascial position are reported. The indications for this t...

    journal_title:Plastic and reconstructive surgery

    pub_type: 杂志文章


    authors: Stoff-Khalili MA,Scholze R,Morgan WR,Metcalf JD

    更新日期:2004-10-01 00:00:00

  • Cranial particulate bone graft ossifies calvarial defects by osteogenesis.

    abstract:BACKGROUND:Cranial particulate bone graft heals inlay calvarial defects and can be harvested as early as infancy. The purpose of this study was to test the hypothesis that particulate bone promotes ossification primarily by osteogenesis. METHODS:Freshly harvested particulate bone, devitalized particulate bone, and hig...

    journal_title:Plastic and reconstructive surgery

    pub_type: 杂志文章


    authors: Hassanein AH,Arany PR,Couto RA,Clune JE,Glowacki J,Rogers GF,Mulliken JB,Greene AK

    更新日期:2012-05-01 00:00:00

  • The Importance of Reproducibility in Plastic Surgery Research.

    abstract::With the advent of big data and database-driven research, the need for reproducible methods has become especially relevant. Given the rise of evidence-based practice, it is crucial to ensure that findings making use of big data can be consistently replicated by other physician-scientists. A call for transparency and r...

    journal_title:Plastic and reconstructive surgery

    pub_type: 杂志文章


    authors: Ascha M,Ascha MS,Gatherwright J

    更新日期:2019-07-01 00:00:00

  • Another method to prevent venous thrombosis in microsurgery: an in situ venous catheter.

    abstract::Free-flap failure is in the order of 4 to 10 percent. Heparin is more effective at preventing venous thrombosis than arterial thrombosis. This study was undertaken to investigate the efficacy of delivering heparin at a high dose locally but low dose systemically (heparin infusion via a catheter placed proximal to the ...

    journal_title:Plastic and reconstructive surgery

    pub_type: 杂志文章


    authors: Hudson DA,Engelbrecht G,Duminy FJ

    更新日期:2000-03-01 00:00:00

  • Prevention of microvascular thrombosis with low-dose tissue plasminogen activator.

    abstract::In a blind, randomized study, two groups, each of seven rabbits, were treated with either a very low dose of human melanoma cell line-derived tissue-type plasminogen activator (t-PA) or isotonic saline. t-PA (0.067 mg/kg of body weight) was administered intraaortically, 20 percent being given as a 30-second "bolus" in...

    journal_title:Plastic and reconstructive surgery

    pub_type: 杂志文章


    authors: Arnljots B,Wieslander JB,Dougan P,Salemark L

    更新日期:1992-08-01 00:00:00

  • Efficacy and Safety of Cell-Assisted Lipotransfer: A Systematic Review and Meta-Analysis.

    abstract:BACKGROUND:The main drawback of autologous fat grafting, which is commonly used for soft-tissue augmentation, is the high resorption rate. Cell-assisted lipotransfer has been used to improve fat graft survival; however, evidence for its efficacy and safety is still lacking. METHODS:The authors searched PubMed, Cochran...

    journal_title:Plastic and reconstructive surgery

    pub_type: 杂志文章,meta分析,评审


    authors: Zhou Y,Wang J,Li H,Liang X,Bae J,Huang X,Li Q

    更新日期:2016-01-01 00:00:00

  • The role of biofilms: are we hitting the right target?

    abstract:BACKGROUND:Chronic infections affect 17 million people yearly, and approximately 550,000 people die each year from, or with, their chronic infections. Acute and chornic infection differences are well known to clinicians, but the role of bacteria in producing these clinical differences remains poorly understood. METHOD...

    journal_title:Plastic and reconstructive surgery

    pub_type: 杂志文章,评审


    authors: Wolcott R,Dowd S

    更新日期:2011-01-01 00:00:00

  • Proximal peroneal perforator in dual-skin paddle configuration of fibula free flap for composite oral reconstruction.

    abstract:BACKGROUND:Composite defects of the oral cavity are often the result of trauma or advanced-stage tumor extirpation. The resultant deformity frequently requires a three-dimensional reconstruction of bone and soft-tissue. The fibula free flap is the preferred method of reconstruction, with various modifications focused o...

    journal_title:Plastic and reconstructive surgery

    pub_type: 杂志文章


    authors: Potter JK,Lee MR,Oxford L,Wong C,Saint-Cyr M

    更新日期:2014-06-01 00:00:00

  • Adipose tissue-derived stromal cells inhibit TGF-β1-induced differentiation of human dermal fibroblasts and keloid scar-derived fibroblasts in a paracrine fashion.

    abstract:BACKGROUND:Adipose tissue-derived stromal cells augment wound healing and skin regeneration. It is unknown whether and how they can also influence dermal scarring. The authors hypothesized that adipose tissue-derived stromal cells inhibit adverse differentiation of dermal fibroblasts induced by the pivotal factor in sc...

    journal_title:Plastic and reconstructive surgery

    pub_type: 杂志文章


    authors: Spiekman M,Przybyt E,Plantinga JA,Gibbs S,van der Lei B,Harmsen MC

    更新日期:2014-10-01 00:00:00

  • Pyoderma gangrenosum: skin grafting after preparation with hyperbaric oxygen.

    abstract::Four patients with pyoderma gangrenosum were treated with hyperbaric oxygen to prepare the wounds for skin grafting. Each wound responded to a course of daily hyperbaric oxygen with reduction of infection and increased capillary angiogenesis. During follow-up periods of 12 to 30 months, all wounds remained healed. Alt...

    journal_title:Plastic and reconstructive surgery

    pub_type: 杂志文章


    authors: Davis JC,Landeen JM,Levine RA

    更新日期:1987-02-01 00:00:00

  • The effects of heparin and dietary fish oil on embolic events and the microcirculation downstream from a small-artery repair.

    abstract::In recent studies we demonstrated that platelet emboli induced by arterial injury impair the microcirculation. The present study was performed to determine if heparin or dietary cod liver oil reduces the incidence of emboli following the same arterial injury and, in turn, whether these agents prevent the associated de...

    journal_title:Plastic and reconstructive surgery

    pub_type: 杂志文章


    authors: Barker JH,Gu JM,Anderson GL,O'Shaughnessy M,Pierangeli S,Johnson P,Galletti G,Acland RD

    更新日期:1993-02-01 00:00:00

  • Alar rim excision: a method of thinning bulky nostrils.

    abstract::A thick nostril is a disturbing deformity and one for which surgeons and patients may be reluctant to employ the traditional "piece of pie" skin excisions commonly described. As an alternative in selected circumstances, a method of internally thinning the nostril rim using an alar base groove incision known as alar ri...

    journal_title:Plastic and reconstructive surgery

    pub_type: 杂志文章


    authors: Matarasso A

    更新日期:1996-04-01 00:00:00

  • Can You Trust What You Watch? An Assessment of the Quality of Information in Aesthetic Surgery Videos on YouTube.

    abstract:BACKGROUND:Videos on YouTube can be posted without regulation or content oversight. Unfortunately, many patients use YouTube as a resource on aesthetic surgery, leading to misinformation. Currently, there are no objective assessments of the quality of information on YouTube about aesthetic surgery. METHODS:YouTube was...

    journal_title:Plastic and reconstructive surgery

    pub_type: 杂志文章


    authors: Gray MC,Gemmiti A,Ata A,Jun B,Johnson PK,Ricci JA,Patel A

    更新日期:2020-02-01 00:00:00

  • The use of resorbable spacers for nasal spreader grafts.

    abstract::The concept and technique of the use of resorbable synthetic material for nasal spreader grafts are presented. The material is felt to be particularly useful in revision rhinoplasty, in which the likelihood of internal valve collapse is high and the septum (the most common source of material for spreader grafts) often...

    journal_title:Plastic and reconstructive surgery

    pub_type: 杂志文章


    authors: Stal S,Hollier L

    更新日期:2000-09-01 00:00:00

  • Reverse dorsal digital island flap.

    abstract::The anatomic and clinical bases for a reliable and versatile homodigital flap for covering difficult distal dorsal and dorsolateral wounds of the long fingers are presented. This one-step procedure, which uses the dorsal skin of the first or second phalanx transposed as a reverse island flap, preserving the collateral...

    journal_title:Plastic and reconstructive surgery

    pub_type: 杂志文章


    authors: Bene MD,Petrolati M,Raimondi P,Tremolada C,Muset A

    更新日期:1994-03-01 00:00:00

  • Transplantation of purified autologous fat: a 3-year follow-up is disappointing.

    abstract::The idea of autologous fat microtransplants has recently resurfaced because of interest by the press. Past experiments have shown that small amounts of fat may be transplanted with an expected survival rate between 10 and 50 percent without ectodermis. A great fund of knowledge exists showing that skin grafts will sur...

    journal_title:Plastic and reconstructive surgery

    pub_type: 杂志文章


    authors: Ersek RA

    更新日期:1991-02-01 00:00:00

  • A clinical trial in facial fat grafting: filtered and washed versus centrifuged fat.

    abstract:BACKGROUND:Although the increasing trend is to rebuild facial soft-tissue volume with autologous fat transfer, there is no agreement concerning the best way of processing the harvested fat before reinjecting it. Among all the reported fat graft processing techniques, in the present study, the authors compared the clini...

    journal_title:Plastic and reconstructive surgery

    pub_type: 杂志文章


    authors: Botti G,Pascali M,Botti C,Bodog F,Cervelli V

    更新日期:2011-06-01 00:00:00

  • Frontal sinus fractures: guidelines to management.

    abstract::The appropriate management of frontal sinus fractures is controversial. Experience with 78 frontal sinus fractures over a 9-year period was reviewed, and the fractures were classified into anterior wall, anterobasilar, and frontal skull fracture extensions. The presence of a concomitant CSF leak or an air-fluid level ...

    journal_title:Plastic and reconstructive surgery

    pub_type: 杂志文章


    authors: Luce EA

    更新日期:1987-10-01 00:00:00

  • Total Face, Eyelids, Ears, Scalp, and Skeletal Subunit Transplant Cadaver Simulation: The Culmination of Aesthetic, Craniofacial, and Microsurgery Principles.

    abstract:BACKGROUND:The application of aesthetic, craniofacial, and microsurgical principles in the execution of face transplantation may improve outcomes. Optimal soft-tissue face transplantation can be achieved by incorporating subunit facial skeletal replacement and subsequent tissue resuspension. The purpose of this study w...

    journal_title:Plastic and reconstructive surgery

    pub_type: 杂志文章


    authors: Sosin M,Ceradini DJ,Hazen A,Levine JP,Staffenberg DA,Saadeh PB,Flores RL,Brecht LE,Bernstein GL,Rodriguez ED

    更新日期:2016-05-01 00:00:00

  • Benefits of the CO2 laser in oral hemangioma excision.

    abstract::Twenty-one patients with small localized oral cavity hemangiomas of the lips, tongue, and buccal mucosa are reported in this series. Although the lesions were not massive or high-flow/high-pressure vascular tumors, the simultaneous cutting and coagulation capabilities of the CO2 laser were demonstrated, rendering such...

    journal_title:Plastic and reconstructive surgery

    pub_type: 杂志文章


    authors: Apfelberg DB,Maser MR,Lash H,White DN

    更新日期:1985-01-01 00:00:00

  • The effect of cigarette smoking on the survival of free vascularized and pedicled epigastric flaps in the rat.

    abstract::Microsurgeons suspect that cigarette smoking reduces the survival of free vascularized flaps and replantations, but this has never been proven. This experimental study investigates the effect of smoking on free-flap survival. A fasciocutaneous epigastric flap was used in 30 rats as a free flap and in 30 rats as a pedi...

    journal_title:Plastic and reconstructive surgery

    pub_type: 杂志文章


    authors: van Adrichem LN,Hoegen R,Hovius SE,Kort WJ,van Strik R,Vuzevski VD,van der Meulen JC

    更新日期:1996-01-01 00:00:00

  • Single-stage repair of asymmetrical bilateral cleft lip with contralateral lesser form defects.

    abstract:BACKGROUND:Complete or incomplete cleft lip may include a contralateral lesser form of incomplete cleft lip to give rise to an asymmetrical bilateral cleft lip deformity. The principle of simultaneous bilateral cleft repair remains an area of contention with regard to asymmetrical cases, including a lesser form deformi...

    journal_title:Plastic and reconstructive surgery

    pub_type: 杂志文章


    authors: Bezuhly M,Fisher DM

    更新日期:2012-03-01 00:00:00

  • Dermal suspension and parenchymal reshaping mastopexy after massive weight loss: statistical analysis with concomitant procedures from a prospective registry.

    abstract:BACKGROUND:An increasing number of women are presenting for mastopexy after massive weight loss. The authors analyzed data from a prospective registry of massive weight loss patients who underwent the dermal suspension and parenchymal reshaping mastopexy alone or with concomitant operations to assess safety and efficac...

    journal_title:Plastic and reconstructive surgery

    pub_type: 杂志文章


    authors: Rubin JP,Gusenoff JA,Coon D

    更新日期:2009-03-01 00:00:00

  • Comparison between rapid and slow tissue expansion in breast reconstruction.

    abstract::Fifty women scheduled for breast reconstruction surgery with tissue expansion were randomly divided into two groups. In the first group the tissue was expanded rapidly, i.e., once a day, starting 1 week postoperatively, and in the other group it was expanded slowly, i.e., once a week, starting after 2 weeks. The expan...

    journal_title:Plastic and reconstructive surgery

    pub_type: 临床试验,杂志文章,随机对照试验


    authors: Wickman M

    更新日期:1993-04-01 00:00:00

  • Slow, gradual external fixation distraction for treatment of postburn knee flexion contracture.

    abstract::Although surgical release and reconstruction have been used extensively to treat severe postburn knee flexion contractures, the degree of correction is sometimes unsatisfactory, and the procedure is not exempt from significant complications. Based on the principle of slow, gradual external fixation distraction, we hav...

    journal_title:Plastic and reconstructive surgery

    pub_type: 杂志文章


    authors: Barquet A,Suero C,Cortés O,López L

    更新日期:1993-04-01 00:00:00

  • Delayed-immediate breast reconstruction: technical and timing considerations.

    abstract:BACKGROUND:In 2002, the author implemented a new two-stage approach, "delayed-immediate breast reconstruction," for patients who desire breast reconstruction and who are at an increased risk for conditions necessitating postmastectomy radiotherapy. There is increasing acceptance of this approach in clinical practice. T...

    journal_title:Plastic and reconstructive surgery

    pub_type: 杂志文章


    authors: Kronowitz SJ

    更新日期:2010-02-01 00:00:00

  • The impact of Smad3 loss of function on TGF-β signaling and radiation-induced capsular contracture.

    abstract:BACKGROUND:Capsular contracture remains a major problem following prosthetic breast implantation, especially in patients undergoing irradiation. Recent studies suggest that such radiation injuries are a cascading process of cytokine activation, with transforming growth factor (TGF)-β acting as the "master switch." Beca...

    journal_title:Plastic and reconstructive surgery

    pub_type: 杂志文章


    authors: Katzel EB,Koltz PF,Tierney R,Williams JP,Awad HA,O'Keefe RJ,Langstein HN

    更新日期:2011-06-01 00:00:00