Detection of Bartonella henselae by polymerase chain reaction in brain tissue of an immunocompromised patient with multiple enhancing lesions. Case report and review of the literature.

Abstract:

:The authors report the first DNA-based diagnosis of Bartonella henselae cultured from a brain lesion in a patient with acquired immune deficiency syndrome. This human immunodeficiency virus-infected patient presented with altered mental status, fever, and diabetes insipidus. Magnetic resonance imaging revealed multifocal parenchymal and leptomeningeal involvement, which was confirmed on studies of tissue biopsy samples. Using the polymerase chain reaction and gene sequencing techniques, the authors definitively demonstrated the presence of B. henselae in the brain tissue biopsy specimen.

journal_name

J Neurosurg

journal_title

Journal of neurosurgery

authors

George TI,Manley G,Koehler JE,Hung VS,McDermott M,Bollen A

doi

10.3171/jns.1998.89.4.0640

subject

Has Abstract

pub_date

1998-10-01 00:00:00

pages

640-4

issue

4

eissn

0022-3085

issn

1933-0693

journal_volume

89

pub_type

杂志文章,评审
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  • Proximal occlusion of the anterior cerebral artery for anterior communicating aneurysm.

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  • Neurenteric cysts in children: 16 consecutive cases and review of the literature.

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