Comparison of 0.5% ropivacaine and 0.5% bupivacaine for epidural anesthesia in patients undergoing lower-extremity surgery.

abstract：:The duration of action and the pharmacokinetics of vecuronium were compared in patients with and without renal function. Twenty patients were studied: 12 with renal failure who were to receive kidney transplants from cadaveric donors, and eight with normal renal function. After oral premedication with diazepam, 10 mg,...

journal_title：Anesthesiology

authors： Lynam DP,Cronnelly R,Castagnoli KP,Canfell PC,Caldwell J,Arden J,Miller RD

更新日期：1988-08-01 00:00:00

abstract：BACKGROUND:Selective breeding produces animal strains with varying anesthetic sensitivity. It thus seems unlikely that various human ethnicities have identical anesthetic requirements. Therefore, the authors tested the hypothesis that the minimum alveolar concentration of sevoflurane differs significantly as a function...

journal_title：Anesthesiology

authors： Ezri T,Sessler D,Weisenberg M,Muzikant G,Protianov M,Mascha E,Evron S

更新日期：2007-07-01 00:00:00

abstract：BACKGROUND:Renal and hepatic toxicity of the fluorinated ether volatile anesthetics is caused by biotransformation to toxic metabolites. Metabolism also contributes significantly to the elimination pharmacokinetics of some volatile agents. Although innumerable studies have explored anesthetic metabolism in animals, the...

journal_title：Anesthesiology

authors： Kharasch ED,Thummel KE

更新日期：1993-10-01 00:00:00

abstract：:There has been a dramatic growth of scholarly articles in medical education in recent years. Evaluating medical education research requires specific orientation to issues related to format and content. Our goal is to review the quantitative aspects of research in medical education so that clinicians may understand the...

journal_title：Anesthesiology

authors： Ratelle JT,Sawatsky AP,Beckman TJ

更新日期：2019-07-01 00:00:00

abstract：BACKGROUND:Experimental and clinical studies have shown reduction in intrapulmonary shunt with improved oxygenation by spontaneous breathing with airway pressure release ventilation (APRV) in acute lung injury. The mechanisms of these findings are not clear. The authors hypothesized that spontaneous breathing results i...

journal_title：Anesthesiology

authors： Wrigge H,Zinserling J,Neumann P,Defosse J,Magnusson A,Putensen C,Hedenstierna G

更新日期：2003-08-01 00:00:00

abstract：BACKGROUND:Melanocortin peptides improve hemodynamic parameters and prevent death during severe hemorrhagic shock. In the present research we determined influences of a synthetic melanocortin 1/4 receptor agonist on the molecular changes that occur in rat liver during hemorrhage. METHODS:Controlled-volume hemorrhage w...

journal_title：Anesthesiology

authors： Lonati C,Sordi A,Giuliani D,Spaccapelo L,Leonardi P,Carlin A,Ottani A,Galantucci M,Grieco P,Catania A,Guarini S

更新日期：2012-03-01 00:00:00

abstract：BACKGROUND:Mask ventilation is an essential element of airway management that has rarely been studied as the primary outcome. The authors sought to determine the incidence and predictors of difficult and impossible mask ventilation. METHODS:A four-point scale to grade difficulty in performing mask ventilation (MV) is ...

journal_title：Anesthesiology

authors： Kheterpal S,Han R,Tremper KK,Shanks A,Tait AR,O'Reilly M,Ludwig TA

更新日期：2006-11-01 00:00:00

abstract：:The pattern of breathing and lung mechanics were evaluated during the first 7 h of life in full-term healthy newborns delivered by cesarean section with bupivacaine epidural anesthesia, without (group 1) or with the addition of 100 micrograms of fentanyl (group 2). Respiration and oxyhemoglobin saturation (SpO2) were ...

journal_title：Anesthesiology

authors： Benlabed M,Dreizzen E,Ecoffey C,Escourrou P,Migdal M,Gaultier C

更新日期：1990-12-01 00:00:00

abstract：:The effects of anesthetic drugs on lipid order were evaluated by the fluorescence polarization of the probe molecule, 1,6-diphenyl-1,3,5-hexatriene (DPH) incorporated into vesicles of dimyristoylphosphatidylcholine (DMPC) and DMPC with 10 mol% ganglioside (GD1a). Anesthetics (enflurane, chloroform, diethylether, pento...

journal_title：Anesthesiology

authors： Harris RA,Groh GI

更新日期：1985-02-01 00:00:00

abstract：BACKGROUND:Acute kidney injury is a common complication after cardiac surgery, leading to increased morbidity and mortality. One suggested cause for acute kidney injury is extracorporeal circulation-induced ischemia-reperfusion injury. In animal studies, cyclosporine has been shown to reduce ischemia-reperfusion injury...

journal_title：Anesthesiology

authors： Ederoth P,Dardashti A,Grins E,Brondén B,Metzsch C,Erdling A,Nozohoor S,Mokhtari A,Hansson MJ,Elmér E,Algotsson L,Jovinge S,Bjursten H

更新日期：2018-04-01 00:00:00

abstract：BACKGROUND:Use of high-dose inhalational anesthesia during open fetal surgery may induce maternal-fetal hemodynamic instability and fetal myocardial depression. The authors' preliminary human retrospective study demonstrated less fetal bradycardia and left ventricular systolic dysfunction with lower dose desflurane sup...

journal_title：Anesthesiology

authors： Ngamprasertwong P,Michelfelder EC,Arbabi S,Choi YS,Statile C,Ding L,Boat A,Eghtesady P,Holland K,Sadhasivam S

更新日期：2013-04-01 00:00:00

abstract：:The effect of enflurane (2% and 4% inspired) on left ventricular (LV) function were examined in chronically instrumented dogs, both intact and after isolation of their hearts and lungs from the systemic circulation. Enflurane in the intact dogs increased heart rate (32 +/- 5% with 2% and 41 +/- 4% with 4%) and elicite...

journal_title：Anesthesiology

authors： Zimpfer M,Gilly H,Krösl P,Schlag G,Steinbereithner K

更新日期：1983-02-01 00:00:00

abstract：BACKGROUND:Positive end expiratory pressure (PEEP) is an important component of therapy in patients with acute lung injury or acute respiratory distress syndrome. The independent effect of PEEP on mortality is currently unknown. METHODS:A systematic review and meta-analysis of randomized controlled clinical trials com...

journal_title：Anesthesiology

authors： Phoenix SI,Paravastu S,Columb M,Vincent JL,Nirmalan M

更新日期：2009-05-01 00:00:00

abstract：BACKGROUND:The effects of triiodothyronine (T3) on systemic hemodynamics, myocardial contractility (preload recruitable stroke work slope; Mw), and left ventricular (LV) isovolumic relaxation (time constant; tau) were examined before and after the development of pacing-induced cardiomyopathy in conscious dogs. METHODS...

journal_title：Anesthesiology

authors： Jamall IN,Pagel PS,Hettrick DA,Lowe D,Kersten JR,Tessmer JP,Warltier DC

更新日期：1997-07-01 00:00:00

abstract：:Fourteen cases of sudden cardiac arrest in healthy patients who received spinal anesthesia were discovered in a preliminary review of 900 closed insurance claims for major anesthetic mishaps. All patients were resuscitated from the intraoperative cardiac arrest, but six suffered such severe neurologic injury that they...

journal_title：Anesthesiology

authors： Caplan RA,Ward RJ,Posner K,Cheney FW

更新日期：1988-01-01 00:00:00

abstract：WHAT WE ALREADY KNOW ABOUT THIS TOPIC:WHAT THIS ARTICLE TELLS US THAT IS NEW: BACKGROUND:: Craniotomy for brain tumor displays significant morbidity and mortality, and no score is available to discriminate high-risk patients. Our objective was to validate a prediction score for postoperative neurosurgical complications...

journal_title：Anesthesiology

authors： Cinotti R,Bruder N,Srairi M,Paugam-Burtz C,Beloeil H,Pottecher J,Geeraerts T,Atthar V,Guéguen A,Triglia T,Josserand J,Vigouroux D,Viquesnel S,Lakhal K,Galliez M,Blanloeil Y,Le Thuaut A,Feuillet F,Rozec B,Asehnoune K

更新日期：2018-12-01 00:00:00

abstract：BACKGROUND:During experimental cardiac arrest, continuous insufflation of air or oxygen (CIO) through microcannulas inserted into the inner wall of a modified intubation tube and generating a permanent positive intrathoracic pressure, combined with external cardiac massage, has previously been shown to be as effective ...

journal_title：Anesthesiology

authors： Saïssy JM,Boussignac G,Cheptel E,Rouvin B,Fontaine D,Bargues L,Levecque JP,Michel A,Brochard L

更新日期：2000-06-01 00:00:00

abstract：BACKGROUND:Glutamate has been implicated in the pathophysiology of neuronal injury associated with cerebral hypoxia-ischemia. A model using chronic in utero microdialysis was developed to sample the extracellular space of the fetal brain. Using this model, we tested the hypothesis that glutamate efflux from the parasag...

journal_title：Anesthesiology

authors： Penning DH,Chestnut DH,Dexter F,Hrdy J,Poduska D,Atkins B

更新日期：1995-02-01 00:00:00

abstract：BACKGROUND:The goal of this study was to identify interventions that anesthesiologists can make to decrease total costs of a postanesthesia care unit (PACU). METHODS:Data were collected retrospectively from patients who underwent ambulatory surgery at our tertiary care center. RESULTS:Supplies and medications account...

journal_title：Anesthesiology

authors： Dexter F,Tinker JH

更新日期：1995-01-01 00:00:00

abstract：:Cognitive performance in postsurgical patients may be impaired by disturbances of normal circadian rhythm analogous to those produced by rapid transmeridian travel ("jet lag"). We therefore tested the hypothesis that isoflurane anesthesia alone produces a phase-delay in the human circadian temperature rhythm. We monit...

journal_title：Anesthesiology

authors： Sessler DI,Lee KA,McGuire J

更新日期：1991-12-01 00:00:00

abstract：BACKGROUND:Renal ischemia-reperfusion injury (IRI) is a major cause of acute kidney injury and often leads to multiorgan dysfunction and systemic inflammation. Volatile anesthetics have potent antiinflammatory effects. We aimed to determine whether the representative volatile anesthetic isoflurane protects against acut...

journal_title：Anesthesiology

authors： Kim M,Park SW,Kim M,D'Agati VD,Lee HT

更新日期：2011-02-01 00:00:00

abstract：BACKGROUND:Systemic inflammation is a key feature in acid aspiration-induced acute respiratory distress syndrome (ARDS), but the factors that trigger inflammation are unclear. The authors hypothesize that extracellular histones, a newly identified inflammatory mediator, play important roles in the pathogenesis of ARDS....

journal_title：Anesthesiology

authors： Zhang Y,Wen Z,Guan L,Jiang P,Gu T,Zhao J,Lv X,Wen T

更新日期：2015-01-01 00:00:00

abstract：BACKGROUND:Lactate has been shown to be a prognostic biomarker in trauma. Although lactate clearance has already been proposed as an intermediate endpoint in randomized trials, its precise role in trauma patients remains to be determined. METHODS:Blood lactate levels and lactate clearance (LC) were calculated at admis...

journal_title：Anesthesiology

authors： Régnier MA,Raux M,Le Manach Y,Asencio Y,Gaillard J,Devilliers C,Langeron O,Riou B

更新日期：2012-12-01 00:00:00

abstract：:The effects of enflurane, halothane, and isoflurane on myocardial potentiated-state contractions were examined in a study in which each of the anesthetics was presented, in random order, to each of eight isolated rabbit papillary muscles. Post-rest potentiated-state contractions were elicited by imposing a stimulus at...

journal_title：Anesthesiology

authors： DeTraglia MC,Komai H,Rusy BF

更新日期：1988-04-01 00:00:00

abstract：BACKGROUND:Hydroxyethyl starch (HES) is commonly used as plasma expander during surgery but may be nephrotoxic as seen in studies in patients with sepsis. The authors hypothesized that the possible nephrotoxicity of 6% HES 130/0.4 could be revealed by measurements of urinary excretion of neutrophil gelatinase-associate...

journal_title：Anesthesiology

authors： Kancir AS,Pleckaitiene L,Hansen TB,Ekeløf NP,Pedersen EB

更新日期：2014-11-01 00:00:00

abstract：BACKGROUND:The main cause of unsuccessful peripheral radial artery catheterization using traditional palpation is imprecisely locating the arterial center. The authors evaluated factors causing disparities between the arterial centers determined by palpation versus ultrasound. The authors applied them to create and tes...

journal_title：Anesthesiology

authors： Nakayama Y,Inagaki Y,Nakajima Y,Sessler DI,Mukai N,Ogawa S,Mizobe T,Sawa T

更新日期：2016-10-01 00:00:00

abstract：BACKGROUND:The cardiovascular side effects of volatile anesthetics are one of the chief causes of postoperative complications in children, and infants seem to be at the greatest risk for this. This study compared cardiovascular changes at equipotent concentrations of sevoflurane and halothane in infants. METHODS:Thirt...

journal_title：Anesthesiology

authors： Wodey E,Pladys P,Copin C,Lucas MM,Chaumont A,Carre P,Lelong B,Azzis O,Ecoffey C

更新日期：1997-10-01 00:00:00

abstract：BACKGROUND:Surgery causes changes in hemostasis, leading to a hypercoagulable state. This postoperative increase in hemostatic function is attenuated in patients receiving regional anesthesia compared with those receiving general anesthesia. Regional anesthesia also decreases the neuroendocrine response to surgery comp...

journal_title：Anesthesiology

authors： Rosenfeld BA,Faraday N,Campbell D,Dise K,Bell W,Goldschmidt P

更新日期：1994-11-01 00:00:00

abstract：BACKGROUND:The distribution and elimination of 0.9% saline given by intravenous infusion has not been compared between the conscious state and during inhalational anesthesia. METHODS:Six adult sheep received an intravenous infusion of 25 ml/kg of 0.9% saline over 20 min in the conscious state and also during isofluran...

journal_title：Anesthesiology

authors： Brauer KI,Svensén C,Hahn RG,Traber LD,Prough DS

更新日期：2002-02-01 00:00:00

abstract：:The tape recorded EEGs of 127 patients anesthetized with large doses of opioids were retrospectively analyzed for evidence of opioid-induced seizures, and in particular, correlated with movements that occurred during induction and could be clinically interpreted as seizures. Bilateral EEG leads in patients receiving f...

journal_title：Anesthesiology

authors： Smith NT,Benthuysen JL,Bickford RG,Sanford TJ,Blasco T,Duke PC,Head N,Dec-Silver H

更新日期：1989-12-01 00:00:00