Frequency of inhaled metaproterenol in the treatment of acute asthma exacerbation.

Abstract:

:Acute asthma exacerbations are common complaints in patients who present to the emergency department. A prospective, double-blinded study was designed to evaluate how frequency of dosing of an inhaled beta-agonist, metaproterenol (Alupent inhalation solution) would affect patient response, length of stay in the ED, and admission rates. Forty-one patients initially received a 0.3-mL dose of nebulized metaproterenol followed by two additional doses of either metaproterenol or saline every 20 minutes. While there was no difference in response (forced expiratory volume in one second) in patients at 30 minutes after their arrival, there was an improved response in the metaproterenol group at 60 and 120 minutes. The length of stay in the ED was approximately the same for both groups. There was no significant difference in admission rates. No increase in undesirable side effects (eg, nausea, tremor, palpitations) was seen in the metaproterenol-treated group. Frequent dosing of metaproterenol is useful in asthmatics having acute exacerbations and leads to rapid improvement without an increase in toxicity.

journal_name

Ann Emerg Med

authors

Nelson MS,Hofstadter A,Parker J,Hargis C

doi

10.1016/s0196-0644(05)82134-1

subject

Has Abstract

pub_date

1990-01-01 00:00:00

pages

21-5

issue

1

eissn

0196-0644

issn

1097-6760

pii

S0196-0644(05)82134-1

journal_volume

19

pub_type

临床试验,杂志文章
  • A method for reviewing radio-telemetry paramedic calls.

    abstract::A method is presented for reviewing the taped radio-telemetry records of paramedic calls managed by hospital-based emergency medicine residents. All paramedic calls to the LAC/USC base station are reviewed by an emergency medicine resident using a special tape review form which focuses on communication skills, initial...

    journal_title:Annals of emergency medicine

    pub_type: 杂志文章

    doi:10.1016/s0196-0644(81)80458-1

    authors: Rottman SJ,FitzGerald-Westby K

    更新日期:1981-01-01 00:00:00

  • An emergency department-based randomized trial of nonbronchoscopic bronchoalveolar lavage for early pathogen identification in severe community-acquired pneumonia.

    abstract:STUDY OBJECTIVES:Many patients with community-acquired pneumonia are treated empirically without an aggressive search for causative pathogens, an approach adopted largely because of the costs and difficulties encountered during efforts to identify the causative organisms. Blood and sputum cultures are not sensitive, an...

    journal_title:Annals of emergency medicine

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1067/mem.2001.118014

    authors: Rodriguez RM,Fancher ML,Phelps M,Hawkins K,Johnson J,Stacks K,Rossini T,Way M,Holland D

    更新日期:2001-10-01 00:00:00

  • The efficacy of an ACLS training program for resuscitation from cardiac arrest in a rural community.

    abstract:STUDY OBJECTIVE:To determine whether an advanced cardiac life support (ACLS) course in a rural hospital will improve resuscitation success from cardiac arrest. DESIGN:A retrospective case review of all patients in cardiac arrest during a 13-month period before and after the institution of an ACLS training program. SE...

    journal_title:Annals of emergency medicine

    pub_type: 杂志文章

    doi:10.1016/s0196-0644(94)70009-5

    authors: Sanders AB,Berg RA,Burress M,Genova RT,Kern KB,Ewy GA

    更新日期:1994-01-01 00:00:00

  • Cervical lung herniation associated with upper airway obstruction.

    abstract::We present the case of a 6-year-old boy with reactive airway disease who developed cervical lung herniation resulting in compression of the trachea and audible stridor. This association has never been reported in the pediatric age group, and a review of the literature revealed that lung herniation is a rare condition ...

    journal_title:Annals of emergency medicine

    pub_type: 杂志文章

    doi:10.1016/s0196-0644(05)81574-4

    authors: Gonzalez del Rey J,Cunha C

    更新日期:1990-08-01 00:00:00

  • Outcome of patients experiencing cardiac arrest with carbon monoxide poisoning treated with hyperbaric oxygen.

    abstract:STUDY OBJECTIVE:We sought to examine the outcome of a subgroup of patients with extreme carbon monoxide (CO) poisoning, specifically those discovered in cardiac arrest, resuscitated, and subsequently treated with hyperbaric oxygen (HBO(2)). Opinions of hyperbaric medicine physicians regarding the treatment of such pati...

    journal_title:Annals of emergency medicine

    pub_type: 杂志文章

    doi:10.1067/mem.2001.115532

    authors: Hampson NB,Zmaeff JL

    更新日期:2001-07-01 00:00:00

  • Sucrose as an aid to manual reduction of incarcerated rectal prolapse.

    abstract::Incarcerated rectal prolapse is a potential surgical emergency. We report a case in which a simple but effective technique involving the desiccating effect of granulated sugar (sucrose) was used to aid the manual reduction of prolapsed but viable rectal tissue. ...

    journal_title:Annals of emergency medicine

    pub_type: 杂志文章

    doi:10.1016/s0196-0644(97)70174-4

    authors: Coburn WM 3rd,Russell MA,Hofstetter WL

    更新日期:1997-09-01 00:00:00

  • Electronic Mass Casualty Assessment and Planning Scenarios (EMCAPS): development and application of computer modeling to selected National Planning Scenarios for high-consequence events.

    abstract::Few tools exist that are sufficiently robust to allow manipulation of key input variables to produce casualty estimates resulting from high-consequence events reflecting local or specific regions of concern. This article describes the design and utility of a computerized modeling simulation tool, Electronic Mass Casua...

    journal_title:Annals of emergency medicine

    pub_type: 杂志文章

    doi:10.1016/j.annemergmed.2008.09.014

    authors: Scheulen JJ,Thanner MH,Hsu EB,Latimer CK,Brown J,Kelen GD

    更新日期:2009-02-01 00:00:00

  • Managed care and emergency medicine: conflicts, federal law, and California legislation.

    abstract::The traditional use of the American ED, one of unrestricted access by patients and payment for services by insurers, is being questioned in this era of health care reform. Both primary care physicians and managed care organizations have questioned the use of the ED by patients without obvious problems of an emergency ...

    journal_title:Annals of emergency medicine

    pub_type: 杂志文章

    doi:10.1016/s0196-0644(97)70164-1

    authors: Derlet RW,Young GP

    更新日期:1997-09-01 00:00:00

  • Ketamine sedation for pediatric procedures: Part 2, Review and implications.

    abstract::Ketamine produces rapid and consistent pediatric sedation with a predictable onset and recovery time. A wide margin of safety is afforded without the respiratory and cardiovascular depression commonly seen with alternative agents. The efficacy of ketamine is well established in anesthesia and dentistry and has extensi...

    journal_title:Annals of emergency medicine

    pub_type: 杂志文章,评审

    doi:10.1016/s0196-0644(05)82569-7

    authors: Green SM,Johnson NE

    更新日期:1990-09-01 00:00:00

  • Immunologic response to tetanus toxoid in geriatric patients.

    abstract:STUDY OBJECTIVE:Tetanus antibody levels have been shown to be inadequate in 50% of patients older than 65 years. Although immunization recommendations have been made for this age group, the efficacy of this intervention has not been well documented. We sought to determine the difference in tetanus antibody levels after...

    journal_title:Annals of emergency medicine

    pub_type: 杂志文章

    doi:10.1016/s0196-0644(97)70005-2

    authors: Alagappan K,Rennie W,Narang V,Auerbach C

    更新日期:1997-10-01 00:00:00

  • Prophylaxis with zidovudine (AZT) after exposure to human immunodeficiency virus: a brief discussion of the issues for emergency physicians.

    abstract::Sound scientific information with which to determine the true efficacy of zidovudine for prophylaxis will probably not be available soon. Physicians should educate themselves thoroughly on the issues. It is highly recommended that thoughtful discussions of the issue of transmission of HIV from health personnel to pati...

    journal_title:Annals of emergency medicine

    pub_type: 杂志文章

    doi:10.1016/s0196-0644(05)81079-0

    authors: Callaham ML

    更新日期:1991-12-01 00:00:00

  • Adverse Effects of Immune Checkpoint Therapy in Cancer Patients Visiting the Emergency Department of a Comprehensive Cancer Center.

    abstract:STUDY OBJECTIVE:Cancer immunotherapy is evolving rapidly and is transforming cancer care. During the last decade, immune checkpoint therapies have been developed to enhance the immune response; however, specific adverse effects related to autoimmunity are increasingly apparent. This study aims to fill the knowledge gap...

    journal_title:Annals of emergency medicine

    pub_type: 杂志文章

    doi:10.1016/j.annemergmed.2018.04.019

    authors: El Majzoub I,Qdaisat A,Thein KZ,Win MA,Han MM,Jacobson K,Chaftari PS,Prejean M,Reyes-Gibby C,Yeung SJ

    更新日期:2019-01-01 00:00:00

  • Closed thoracic cavity lavage in the treatment of severe hypothermia in human beings.

    abstract::Life-threatening hypothermia can be treated by active and passive rewarming techniques, the treatment of choice being partial cardiopulmonary bypass. The use of closed thoracic cavity lavage has been evaluated in animals, but no formal presentations in human beings have been reported. We report two cases in which rapi...

    journal_title:Annals of emergency medicine

    pub_type: 杂志文章

    doi:10.1016/s0196-0644(05)81810-4

    authors: Hall KN,Syverud SA

    更新日期:1990-02-01 00:00:00

  • The effect of dedicated methodology and statistical review on published manuscript quality.

    abstract:STUDY OBJECTIVE:We examine how dedicated methodology and statistical review affects the quality of manuscripts published in Annals of Emergency Medicine. DESIGN:The dedicated reviewers developed a manuscript scoring form based on previously used instruments. The form contained 84 unique elements. Eight items sought th...

    journal_title:Annals of emergency medicine

    pub_type: 杂志文章

    doi:10.1067/mem.2002.127328

    authors: Schriger DL,Cooper RJ,Wears RL,Waeckerle JF

    更新日期:2002-09-01 00:00:00

  • Vertebrobasilar distribution stroke mimicking transtentorial herniation.

    abstract::Strokes in the vertebrobasilar arterial distribution may result in a variety of physical findings and can be challenging to diagnose. We report a case of a 60-year-old woman with infarction of the left midbrain, right pons, and bilateral thalami with physical findings resembling transtentorial herniation. ...

    journal_title:Annals of emergency medicine

    pub_type: 杂志文章

    doi:10.1016/s0196-0644(98)70212-4

    authors: Lipinski CA,Swanson ER

    更新日期:1998-05-01 00:00:00

  • Graduated driver licensing in Utah: is it effective?

    abstract:STUDY OBJECTIVE:We seek to examine the effectiveness of the graduated driver licensing system in Utah by determining whether crash rates of 16-year-old drivers decreased after graduated driver licensing implementation. METHODS:We studied 16-year-old-driver crashes using statewide motor vehicle crash data probabilistic...

    journal_title:Annals of emergency medicine

    pub_type: 杂志文章

    doi:10.1016/j.annemergmed.2004.10.007

    authors: Hyde LK,Cook LJ,Knight S,Olson LM

    更新日期:2005-02-01 00:00:00

  • The use of glucagon in a case of calcium channel blocker overdose.

    abstract::The hypotension and myocardial depression that result from calcium channel blocker ingestion often are refractory to standard therapeutic modalities. Anecdotal reports on the use of glucagon have failed to show significant hemodynamic improvement. We report the first case of calcium channel blocker overdose that respo...

    journal_title:Annals of emergency medicine

    pub_type: 杂志文章

    doi:10.1016/s0196-0644(05)80997-7

    authors: Doyon S,Roberts JR

    更新日期:1993-07-01 00:00:00

  • Occupational fatalities in emergency medical services: a hidden crisis.

    abstract:STUDY OBJECTIVE:We estimate the occupational fatality rate among emergency medical services (EMS) personnel in the United States. METHODS:We undertook descriptive epidemiology of occupational fatalities among EMS providers. Analysis was conducted by using data from 3 independent fatality databases: the Census of Fatal...

    journal_title:Annals of emergency medicine

    pub_type: 杂志文章

    doi:10.1067/mem.2002.128681

    authors: Maguire BJ,Hunting KL,Smith GS,Levick NR

    更新日期:2002-12-01 00:00:00

  • Single-dose ceftriaxone treatment of urinary tract infections.

    abstract::Single-dose antibiotic therapy for urinary tract infections in which no underlying structural or neurologic lesions are present holds the promise of greater patient compliance and convenience. We present the results of a study comparing a single intramuscular dose of a long-acting, third-generation cephalosporin, ceft...

    journal_title:Annals of emergency medicine

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1016/s0196-0644(85)80239-0

    authors: Rosenberg JM,Levy RC,Cicmanec JF,Hedges JR,Burke BM

    更新日期:1985-10-01 00:00:00

  • Overdose of risperidone.

    abstract::Risperidone is an investigational antipsychotic agent currently being tested in an international multicenter drug trial. We report the first case of a risperidone overdose in an apparent suicide attempt. This was without serious clinical side effects and manifested mainly as ECG abnormalities. ...

    journal_title:Annals of emergency medicine

    pub_type: 杂志文章

    doi:10.1016/s0196-0644(05)80421-4

    authors: Brown K,Levy H,Brenner C,Leffler S,Hamburg EL

    更新日期:1993-12-01 00:00:00

  • The bacteriology of dog bite wounds on initial presentation.

    abstract::Four hundred twenty patients with open dog bite wounds on initial presentation to the emergency department had Gram stains, aerobic and anaerobic cultures, and antibiotic sensitivities of the bacterial isolates of each wound. Forty-eight percent of the wounds evidenced no bacterial growth. Staphylococcus epidermidis w...

    journal_title:Annals of emergency medicine

    pub_type: 杂志文章

    doi:10.1016/s0196-0644(86)80620-5

    authors: Ordog GJ

    更新日期:1986-11-01 00:00:00

  • Effect of magnesium sulfate on ventricular rate control in atrial fibrillation.

    abstract:STUDY OBJECTIVES:The objectives of this study were to assess the efficacy of parenteral magnesium sulfate (MgSO4), digoxin, and combined MgSO4-digoxin therapies in acutely lowering ventricular rates in patients with newly recognized atrial fibrillation. DESIGN:A randomized, double-blinded, placebo-controlled clinical ...

    journal_title:Annals of emergency medicine

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1016/s0196-0644(94)70163-6

    authors: Hays JV,Gilman JK,Rubal BJ

    更新日期:1994-07-01 00:00:00

  • Effect of immediate fluid resuscitation on the rate, volume, and duration of pulmonary vascular hemorrhage in a sheep model of penetrating thoracic trauma.

    abstract:STUDY OBJECTIVE:To determine the effects of early fluid resuscitation on the rate, volume, and duration of hemorrhage using a sheep model of uncontrolled pulmonary vascular hemorrhage. METHODS:Sixteen adult sheep were anesthetized and fitted with catheters to measure systemic and pulmonary artery pressures. A branch o...

    journal_title:Annals of emergency medicine

    pub_type: 杂志文章

    doi:10.1016/s0196-0644(97)70352-4

    authors: Sakles JC,Sena MJ,Knight DA,Davis JM

    更新日期:1997-03-01 00:00:00

  • The effectiveness of bystander CPR in an animal model.

    abstract::Several clinical studies have yielded conflicting results in examining the effectiveness of bystander CPR (BCPR). The purpose of this pilot study was to determine the effectiveness of BCPR in an animal model of cardiac arrest and resuscitation. Ten swine were instrumented for hemodynamic and regional blood flow measur...

    journal_title:Annals of emergency medicine

    pub_type: 杂志文章

    doi:10.1016/s0196-0644(05)81561-6

    authors: Hoekstra JW,Rinnert K,Van Ligten P,Neumar R,Werman HA,Brown CG

    更新日期:1990-08-01 00:00:00

  • Varicella: pediatric genital/rectal vesicular lesions of unclear origin.

    abstract::Three children who presented with localized vesicular rash in the diaper area were found to have primary varicella-zoster infections. Primary varicella can closely mimic genital herpes simplex virus (HSV 1 or 2), which may be an indicator of sexual abuse. To avoid unfounded investigation for sexual abuse, primary vari...

    journal_title:Annals of emergency medicine

    pub_type: 杂志文章

    doi:10.1016/s0196-0644(95)70365-9

    authors: Simon HK,Steele DW

    更新日期:1995-01-01 00:00:00

  • Community trends in CPR training and use: the Minnesota Heart Survey.

    abstract:STUDY OBJECTIVE:To examine community changes in self-reported CPR training and use from 1980-82 to 1985-87 using data obtained from the Minnesota Heart Survey. A comparative investigation of CPR training among blacks and whites in 1985-86 also was completed. DESIGN:Data were obtained in 1980-81, 1981-82, 1985-86, and ...

    journal_title:Annals of emergency medicine

    pub_type: 杂志文章

    doi:10.1016/s0196-0644(05)82782-9

    authors: Naughton MJ,Luepker RV,Sprafka JM,McGovern PG,Burke GL

    更新日期:1992-06-01 00:00:00

  • Training with video imaging improves the initial intubation success rates of paramedic trainees in an operating room setting.

    abstract:STUDY OBJECTIVE:Video imaging of intubation as seen by the laryngoscopist has not been a part of traditional instruction methods, and its potential impact on novice intubation success rates has not been evaluated. METHODS:We prospectively tracked the success rates of novice intubators in paramedic classes who were req...

    journal_title:Annals of emergency medicine

    pub_type: 杂志文章

    doi:10.1067/mem.2001.111516

    authors: Levitan RM,Goldman TS,Bryan DA,Shofer F,Herlich A

    更新日期:2001-01-01 00:00:00

  • Role of emergency medicine residency programs in determining emergency medicine career choice among medical students.

    abstract:STUDY OBJECTIVE:To characterize the role of emergency medicine residency programs in determining emergency medicine career choice among medical students. DESIGN:Observational, cross-sectional, descriptive study. Information on student career choice was obtained through a targeted query of the National Resident Matchin...

    journal_title:Annals of emergency medicine

    pub_type: 杂志文章

    doi:10.1016/s0196-0644(94)70104-0

    authors: Gallagher EJ,Goldfrank LR,Anderson GV Jr,Barsan WG,Levy RC,Sanders AB,Strange GR,Trott AT

    更新日期:1994-05-01 00:00:00

  • Night shift work.

    abstract::The deleterious effects of night shift work are discussed in relation to emergency physicians. Much of the early research is drawn from heavy industry sources and must be extrapolated to medical work. Disruption of circadian rhythms and Zeitgebers, caused by adherence to contemporary social schedules, causes recurrent...

    journal_title:Annals of emergency medicine

    pub_type: 杂志文章

    doi:10.1016/s0196-0644(84)80615-0

    authors: Michaels HE

    更新日期:1984-03-01 00:00:00

  • Measuring response intervals in a system with a 911 primary and an emergency medical services secondary public safety answering point.

    abstract:STUDY OBJECTIVE:Measurement of interval data is important in the accurate recording of events that occur in an emergency medical services system. Measurement of intervals should be a simple task. However, when two separate clocks are needed to record the beginning and end of an interval, accurate measurement may be dif...

    journal_title:Annals of emergency medicine

    pub_type: 杂志文章

    doi:10.1016/s0196-0644(97)70222-1

    authors: Campbell JP,Gridley TS,Muelleman RL

    更新日期:1997-04-01 00:00:00