Abstract:
:Use of antioxidant components is a new approach for improvement of insulin resistance (IR) as a main feature of type 2 diabetes and its complications. The aim of this study was to investigate the effects of broccoli sprouts powder (BSP) containing high concentration of sulphoraphane on IR in type 2 diabetic patients. Eighty-one patients were randomly assigned to receive 10 g/d BSP (A, n = 27), 5 g/d BSP (B, n = 29) and placebo (C, n = 25) for 4 weeks. Fasting serum glucose and insulin concentration, glucose to insulin ratio and homoeostasis model assessment of IR (HOMA-IR) index were measured at baseline and again 4 weeks after treatment. Seventy-two patients completed the study and 63 were included in the analysis. After 4 weeks, consumption of 10 g/d BSP resulted in a significant decrease in serum insulin concentration and HOMA-IR (p = 0.05 for treatment effect). Therefore, broccoli sprouts may improve IR in type 2 diabetic patients.
journal_name
Int J Food Sci Nutrjournal_title
International journal of food sciences and nutritionauthors
Bahadoran Z,Tohidi M,Nazeri P,Mehran M,Azizi F,Mirmiran Pdoi
10.3109/09637486.2012.665043subject
Has Abstractpub_date
2012-11-01 00:00:00pages
767-71issue
7eissn
0963-7486issn
1465-3478journal_volume
63pub_type
杂志文章,随机对照试验abstract:AIMS:The aim of the study was to establish whether the addition of some berries and fruits during quince jam processing, improves its colour and enriches it in polyphenol compounds, other than those found in quince fruits. METHODS:Phenolic compounds were identified and quantified by LC-MS Q/TOF and HPLC. Antioxidant a...
journal_title:International journal of food sciences and nutrition
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