Abstract:
:The possible deleterious effect of meet consumption upon deterioration of renal disease was speculated from Lionel Beale as early as 1869. The first attempt to apply a very low protein diet in humans is attributed to Millard Smith who prescribed a diet consisting of 300 mg protein per day in a volunteer medical student for 24 days. Unfortunately, in early 20(th) century, prescribing very low protein diets among patients suffering from renal disease complicated with malnutrition and the medical practice of this era turned to the recommendation of high protein diets because it was believed that protein consumption is coupled with the strength of civilized man. In mid sixties Giordano and Giovanetti introduced low protein diets in the treatment of uremic patients but their efforts did not accepted from the medical community. Meanwhile the evolution of haemodialysis, peritoneal dialysis and transplantation as effective methods of treating end stage renal disease guided doctors and patients far from privative diets in the era of plenty. The rapidly increasing number of end stage renal disease patients needed substitution of renal function produced a tremendous increase of financial burden upon public health system expenditure and alternative measures of therapy, prevention and delaying chronic kidney disease searched. Unfortunately MDRD study failed to show convincing results of food protein restriction and blood pressure lowering in ameliorating deterioration of renal function and the majority of physicians turned to the practice of early dialysis in an attempt to avoid malnutrition. Despite the increasing knowledge and the appliance of certain guidelines in treating end stage renal disease patients, the morbidity and mortality remain high among this population. The search toward other possible toxic substances showed that phosphorus consumption with diet is another dangerous element exerting its deleterious effect in deteriorating renal function as well as increasing morbidity and mortality. Recently published epidemiological data suggest a very poor outcome of elderly patients, older than 80 years of age, undergoing substitution of renal function by dialysis or peritoneal dialysis and a lot of skepticism arise concerning the beneficial effect of diet and a rigorous effort of rehabilitation of these patients instead of substitution of renal function by either method.
journal_name
Hippokratiajournal_title
Hippokratiaauthors
Koulouridis E,Koulouridis Isubject
Has Abstractpub_date
2011-01-01 00:00:00pages
3-7issue
Suppl 1eissn
1108-4189issn
1790-8019journal_volume
15pub_type
杂志文章相关文献
Hippokratia文献大全abstract::Advances in medicine can reduce active euthanasia of newborns with severe anomalies or unusual prematurity, but they cannot eliminate it. In the Netherlands, voluntary active euthanasia among adults and adolescents has been allowed since 2002, when the so-called Groningen Protocol (GP) was formulated as an extension o...
journal_title:Hippokratia
pub_type: 杂志文章
doi:
更新日期:2014-07-01 00:00:00
abstract:AIM:The assessment of the postoperative outcome following laparoscopic sacrocolpopexy using anterior and posterior mesh. MATERIAL AND METHODS:In the study were included one hundred and ten women (mean age 62 years with range from 34 to 78) who had laparoscopic sarcoplexy the period 2001-2005. They were contacted and c...
journal_title:Hippokratia
pub_type: 杂志文章
doi:
更新日期:2009-04-01 00:00:00
abstract:BACKGROUND AND AIMS:Nonalcoholic fatty liver disease (NAFLD) is the most common chronic liver disease in children and adolescents. Obesity is a major risk factor for NAFLD; however, it has been shown that NAFLD is not rare in non-obese adults. The aim of this study was to determine the prevalence of NAFLD in obese and ...
journal_title:Hippokratia
pub_type: 杂志文章
doi:
更新日期:2012-01-01 00:00:00
abstract:BACKGROUND:The major cause of hereditary renal failure is autosomal dominant polycystic kidney disease (ADPKD). Many factors affect renal progression in these patients. Among these, hypertension and an increase in renal volume are interrelated in terms of their effects on renal progression. We aimed to investigate the ...
journal_title:Hippokratia
pub_type: 杂志文章
doi:
更新日期:2012-04-01 00:00:00
abstract::Pyeloureteritis cystica is a rare situation of the renal pelvis and ureters, characterized by cystical formations of the epithelium. The etiology is unknown and there is no specific treatment. It is usually diagnosed accidently during imaging of the upper urinary tract for different reasons. We present a case of pyelo...
journal_title:Hippokratia
pub_type:
doi:
更新日期:2010-10-01 00:00:00
abstract:OBJECTIVE:Constipation is a frequent problitalic in childhood and may be defined as delay or difficulty in defecation that persists for longer than two weeks. It is one of the ten most frequent pathological conditions that a general paediatrician deals with. The aim of this review is to provide the general paediatricia...
journal_title:Hippokratia
pub_type: 杂志文章,评审
doi:
更新日期:2015-01-01 00:00:00
abstract:BACKGROUND:The syndrome of horizontal gaze palsy with progressive scoliosis (HGPPS) is a rare human disease and while its association with scoliosis was first reported in 1974, thirty years later the responsible genetic mutations are being elucidated. This progress was due to the reporting of single interesting cases. ...
journal_title:Hippokratia
pub_type: 杂志文章
doi:
更新日期:2013-10-01 00:00:00
abstract:BACKGROUND:In the present prospective cross-sectional clinical study, correlations between global quality of life (QoL) and coping strategies were examined in patients who had undergone partial laryngeal resection for T1-T2 laryngeal cancer. METHODS:Correlations between point scores in the "Trier Illness Coping Scale...
journal_title:Hippokratia
pub_type: 杂志文章
doi:
更新日期:2014-04-01 00:00:00
abstract:BACKGROUND:High level of alpha-fetoprotein is usually associated with testis cancer or hepatocellular carcinoma a primary tumor of the liver. CASE:We report the case of a 72-year-old male patient with chronic renal failure who presented with a high alpha-fetoprotein (AFP) level and a retroperitoneal mass, which was su...
journal_title:Hippokratia
pub_type: 杂志文章
doi:
更新日期:2014-01-01 00:00:00
abstract::The case on contact shots from firearms with a flash suppressor is rare. When a rifle fitted with a flash suppressor is fired, the emerging soot-laden gas in the barrel escapes from the slits of the flash suppressor. If the shot is contact or near contact, the flash suppressor will produce a characteristic "flower-lik...
journal_title:Hippokratia
pub_type:
doi:
更新日期:2012-04-01 00:00:00
abstract::Intravenous (IV) paracetamol is widely used for the treatment of pain and fever, when there is a clinical indication for an IV route. A 16-month-old girl weighing 12 kg had undergone anterior open reduction for developmental dysplasia of the hip. Twenty-four hours after the operation, IV paracetamol (Perfalgan® 10 mg/...
journal_title:Hippokratia
pub_type:
doi:
更新日期:2013-01-01 00:00:00
abstract::Diabetic nephropathy is a serious, long-term complication of diabetes and the leading cause of end-stage renal disease throughout the world. Although this disease is progressively imposing a heavier burden on the health care system, in many aspects it remains poorly understood. In addition to environmental influences,...
journal_title:Hippokratia
pub_type: 杂志文章
doi:
更新日期:2011-07-01 00:00:00
abstract:AIM:The aim of the current study was to evaluate the level of the basic knowledge of the Turkish gynecologists regarding electrosurgery. MATERIALS AND METHODS:A survey was undertaken to evaluate the level of basic knowledge and attitudes regarding electrosurgery use among gynecology specialists and residents. The ques...
journal_title:Hippokratia
pub_type: 杂志文章
doi:
更新日期:2017-01-01 00:00:00
abstract::Muscle hydatidosis is rare, accounting only for 3-5% of all cases. We present a case series of 9 patients (8 male, one female, mean age 59.3 years, range 48-75 years) with primary echinococcosis of skeletal muscles. The cysts presented as soft tissue masses in 8 patients, whereas in one, the cyst was an incidental fin...
journal_title:Hippokratia
pub_type:
doi:
更新日期:2010-04-01 00:00:00
abstract:BACKGROUND:Pediatric home care has improved therapeutic options for children with chronic disease. Home intravenous (IV) antibiotic treatment against Pseudomonas aeruginosa (PsA) in cystic fibrosis (CF) patients has offered increased flexibility to these patients and family life. A prospective clinical study was conduc...
journal_title:Hippokratia
pub_type: 杂志文章
doi:
更新日期:2016-10-01 00:00:00
abstract:AIM:The aim of the study was to determine the impact of the duration of diabetes and the control of glycemia on the auditory function of patients with type 2 diabetes mellitus (T2DM). MATERIALS AND METHODS:This prospective study included 80 patients with T2DM (divided depending on when T2DM was diagnosed, and also acc...
journal_title:Hippokratia
pub_type: 杂志文章
doi:
更新日期:2016-01-01 00:00:00
abstract:BACKGROUND:Recent studies provide evidence that peripheral blood monocytes have the ability to differentiate into mesenchymal-like cells. The ability of cultured monocytes to differentiate and produce insulin in vitro is analysed in the present study. METHODS:Peripheral blood monocytes were isolated from healthy donor...
journal_title:Hippokratia
pub_type: 杂志文章
doi:
更新日期:2015-10-01 00:00:00
abstract::Alveolar soft-part sarcoma (ASPS) is a rare form of soft tissue sarcoma and is most often seen in adolescents and young adults. Surgical excision of the primary tumor and pulmonary metastases has resulted in prolonged survival in some patients while the benefit of adjuvant chemotherapy and/or radiotherapy has been dis...
journal_title:Hippokratia
pub_type:
doi:
更新日期:2008-01-01 00:00:00
abstract:BACKGROUND:Bone involvement represents a common symptom at diagnosis in children with acute lymphoblastic leukemia, and its prognostic value is not entirely clarified. The aim of this study was to evaluate bone involvement at diagnosis in children with acute lymphoblastic leukemia as a predictive factor and to correlat...
journal_title:Hippokratia
pub_type: 杂志文章
doi:
更新日期:2016-07-01 00:00:00
abstract::The myelodysplastic syndromes (MDS) remain challenging to the clinician in terms of diagnosis and management. The diagnosis is essentially one of exclusion in first ruling out other disorders that can also cause peripheral blood/bone marrow cell dysplasia and cytopenias. Recent studies implicate extensive apoptosis as...
journal_title:Hippokratia
pub_type: 杂志文章
doi:
更新日期:2007-10-01 00:00:00
abstract:BACKGROUND:The involvement of the immune system in the pathogenesis of certain types of epilepsy has been supported in the past. The use of intravenous immunoglobulin in the treatment of neurologic diseases has shown a progressive trend over the last years. CASE REPORT:We report the case of a 9.5-year-old boy with ref...
journal_title:Hippokratia
pub_type:
doi:
更新日期:2017-01-01 00:00:00
abstract:OBJECTIVE:The objective of this study was to determine the efficacy of the exercises administered to stroke patients with the balance trainer (BALANCE-trainer, art.nr. 07001-001(TM)) on balance, level of independence and ambulation parameters. MATERIAL AND METHOD:Fifty patients with hemiplegia were randomized into eit...
journal_title:Hippokratia
pub_type: 杂志文章
doi:
更新日期:2015-04-01 00:00:00
abstract::Schwannomas are generally benign, slow growing tumors, which can originate from any nerve that has a Schwann cell sheath. Digestive tract schwannomas are rare and are usually asymptomatic. We present the case of a 48-year-old woman with a symptomatic submucosal tumour of the gastric antrum. The patient underwent parti...
journal_title:Hippokratia
pub_type: 杂志文章
doi:
更新日期:2012-07-01 00:00:00
abstract:BACKGROUND:Computer-aided detection in the setting of trauma presents unique challenges due to variations in shape and attenuation of the injured organs based on the timing and severity of the injury. We developed and validated an automated computer-aided diagnosis algorithm to detect splenic lesions such as laceratio...
journal_title:Hippokratia
pub_type: 杂志文章
doi:
更新日期:2018-04-01 00:00:00
abstract:BACKGROUND:To investigate an outbreak of Burkholderia cenocepacia bacteremia. Observational study and chart review in a multidisciplinary adult Intensive Care Unit (ICU) at a tertiary care hospital. METHODS:Patients' demographic variables, comorbid conditions, ICU admission diagnosis, disease severity and outcome were...
journal_title:Hippokratia
pub_type: 杂志文章
doi:
更新日期:2012-10-01 00:00:00
abstract::Metabolic syndrome is a disorder characterized by abdominal obesity, hypertension, increased triglycerides, decreased HDL cholesterol and increased blood glucose. Accumulating evidence strongly indicates that insulin resistance and an increased amount of abdominal fat are the pathogenic factors for the characteristics...
journal_title:Hippokratia
pub_type: 杂志文章
doi:
更新日期:2008-04-01 00:00:00
abstract:BACKGROUND:Hepatic cirrhosis caused by hepatic steatosis and hepatitis is irreversible. Early and non-invasive diagnosis of these diffuse hepatopathies calls for possible imaging markers. The purpose of this study was to explore the changes in global hepatic glucose metabolism following hepatic steatosis, hepatitis, or...
journal_title:Hippokratia
pub_type: 杂志文章
doi:
更新日期:2018-10-01 00:00:00
abstract::Albeit the considerable progress that has been made both in our understanding of the pathophysiology of acute renal failure (ARF) and in its treatment (continuous renal replacement therapies), the morbidity of this complex syndrome remains unacceptably high. The current review focuses on recent developments concerning...
journal_title:Hippokratia
pub_type: 杂志文章
doi:
更新日期:2011-01-01 00:00:00
abstract:BACKGROUND:This study was performed to investigate nutritional parameters of hemodialysis patients by using anthropometric and biochemical measurements. METHODS:Data from the last 6 months of 22 adult hemodialysis patients with a mean age of 61 ± 14 years were analyzed retrospectively. Dialysis vintage, normalized pro...
journal_title:Hippokratia
pub_type: 杂志文章
doi:
更新日期:2012-07-01 00:00:00
abstract::Vitamin D has many physiological functions. First it is a primary regulator of calcium homeostasis. Beyond that, vitamin D and its receptors (VDR) play important role in the immune system, cardiovascular system, reproductive system and insulin resistance. An important aspect of vitamin D pleiotropic effects is the int...
journal_title:Hippokratia
pub_type: 杂志文章,评审
doi:
更新日期:2011-10-01 00:00:00