General principles of hepatectomy in colorectal liver metastases.

Abstract:

:Hepatic resection for colorectal liver metastases remains the only therapeutic option that improves long-term survival and offers potential cure. By conventional resectability criteria, only a limited number of patients with metastatic disease can be subjected to surgical intervention. In the past decade, better understanding of the natural history of the disease, the introduction of new chemotherapy agents and the advances in surgical techniques have led to more patients being eligible for surgery. Neoadjuvant chemotherapy can reduce the size of the metastases, allowing operation on patients who were previously considered inoperable. Major resections can nowadays be safely performed with the development of new less-invasive techniques and with the use of supplementary tools like ablation techniques. Using portal vein embolization to induce hypertrophy of future liver remnant and combining it with two-staged hepatectomy allow more patients with advanced disease to undergo potentially curative surgery. Careful selection of patients and aggressive surgery in experienced centers improve survival rates.

journal_name

Tech Coloproctol

authors

Maroulis I,Karavias DD,Karavias D

doi

10.1007/s10151-011-0750-0

subject

Has Abstract

pub_date

2011-10-01 00:00:00

pages

S13-6

eissn

1123-6337

issn

1128-045X

journal_volume

15 Suppl 1

pub_type

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