Abstract：
:The induction of hypothermia for cellular protection is well established in several clinical settings. Its role in trauma patients, however, is controversial. This review discusses the benefits and complications of induced hypothermia--emphasizing the current state of knowledge and potential applications in bleeding patients. Extensive pre-clinical data suggest that in advanced stages of shock, rapid cooling can protect cells during ischemia and reperfusion, decrease organ damage, and improve survival. Yet hypothermia is a double edged sword; unless carefully managed, its induction can be associated with a number of complications. Appropriate patient selection requires a thorough understanding of the pre-clinical literature. Clinicians must also appreciate the enormous influence that temperature modulation exerts on various cellular mechanisms. This manuscript aims to provide a balanced view of the published literature on this topic. While many of the advantageous molecular and physiological effects of induced hypothermia have been outlined in animal models, rigorous clinical investigations are needed to translate these promising findings into clinical practice.
journal_name
Scand J Trauma Resusc Emerg Medauthors
Kheirbek T,Kochanek AR,Alam HBdoi
10.1186/1757-7241-17-65subject
Has Abstractpub_date
2009-12-23 00:00:00pages
65issn
1757-7241pii
1757-7241-17-65journal_volume
17pub_type
杂志文章,评审abstract：BACKGROUND:Motor vehicle collisions (MVCs) are a common cause of major trauma and death. Following an MVC, up to 40% of patients will be trapped in their vehicle. Extrication methods are focused on the prevention of secondary spinal injury through movement minimisation and mitigation. This approach is time consuming an...
journal_title：Scandinavian journal of trauma, resuscitation and emergency medicine
pub_type： 杂志文章
doi：10.1186/s13049-020-00818-6
更新日期：2021-01-14 00:00:00
abstract：BACKGROUND:Trauma patients have impaired health-related quality of life (HRQOL) after trauma. The aim of the study was to assess HRQOL during the first year after trauma and hospital stay in trauma patients admitted to an intensive-care unit (ICU) for >24 hours compared with non-ICU trauma patients and the general popu...
journal_title：Scandinavian journal of trauma, resuscitation and emergency medicine
pub_type： 杂志文章
doi：10.1186/1757-7241-19-22
更新日期：2011-04-08 00:00:00
abstract：INTRODUCTION:In former studies from North America early Do-Not-Resuscitate orders (DNR orders) in patients with intracerebral haemorrhage (ICH) had negative prognostic impact on mortality. The influence of DNR orders on functional outcome and whether DNR orders are grounded on relevant patient characteristics is unknow...
journal_title：Scandinavian journal of trauma, resuscitation and emergency medicine
pub_type： 杂志文章
doi：10.1186/1757-7241-20-36
更新日期：2012-05-25 00:00:00
abstract：BACKGROUND:There is substantial variation in the incidence, likelihood of attempted resuscitation and outcomes from out-of-hospital cardiac arrest (OHCA) across Europe. A European, multi-centre study provides the opportunity to uncover differences throughout Europe and may help find explanations for these differences. ...
journal_title：Scandinavian journal of trauma, resuscitation and emergency medicine
pub_type： 杂志文章
doi：10.1186/s13049-015-0093-3
更新日期：2015-01-24 00:00:00
abstract：:In patients with traumatic injury of an upper limb it is often necessary to both secure intravenous (IV) access and record blood pressure noninvasively in the other upper limb. This may cause intermittent obstruction to the flow of IV fluids during cuff inflation. Also backflow of blood into the IV tubing when the cuf...
journal_title：Scandinavian journal of trauma, resuscitation and emergency medicine
pub_type： 杂志文章
doi：10.1186/1757-7241-18-53
更新日期：2010-10-13 00:00:00
abstract：BACKGROUND:An emergency cricothyrotomy is the last-resort in most airway management protocols and is performed when it is not possible to intubate or ventilate a patient. This situation can rapidly prove fatal, making it important to identify the best method to establish a secure airway. We conducted a systematic revie...
journal_title：Scandinavian journal of trauma, resuscitation and emergency medicine
pub_type： 杂志文章,评审
doi：10.1186/1757-7241-21-43
更新日期：2013-05-31 00:00:00
abstract：BACKGROUND:This systematic review and meta-analysis aims to critically compare the outcomes of plate fixation (PF) versus intramedullary fixation (IF) for the treatment of mid-shaft clavicle fractures. METHODS:Relevant original studies were searched in electronic databases of Medline, Embase, Cochrane central database...
journal_title：Scandinavian journal of trauma, resuscitation and emergency medicine
pub_type： 杂志文章,meta分析,评审
doi：10.1186/s13049-015-0108-0
更新日期：2015-03-20 00:00:00
abstract：:Major incidents are resource-demanding situations that require urgent and effective medical management. The possibility to extract learning from them is therefore important. Comparative analysis of information based on uniform data collection from previous incidents may facilitate learning. The Major Incident Reportin...
journal_title：Scandinavian journal of trauma, resuscitation and emergency medicine
pub_type： 杂志文章,评审
doi：10.1186/s13049-015-0132-0
更新日期：2015-08-05 00:00:00
abstract：:There is a general decline in penetrating abdominal trauma throughout the western world. As a result of that, there is a significant loss of expertise in dealing with this type of injury particularly when the patient presents to theatre with physiological instability. A significant percentage of these patients will no...
journal_title：Scandinavian journal of trauma, resuscitation and emergency medicine
pub_type： 杂志文章
doi：10.1186/1757-7241-18-40
更新日期：2010-07-14 00:00:00
abstract：BACKGROUND:Prehospital advanced airway management, including prehospital endotracheal intubation is challenging and recent papers have addressed the need for proper training, skill maintenance and quality control for emergency medical service personnel. The aim of this study was to provide data regarding airway managem...
journal_title：Scandinavian journal of trauma, resuscitation and emergency medicine
pub_type： 杂志文章
doi：10.1186/1757-7241-19-10
更新日期：2011-02-08 00:00:00
abstract：BACKGROUND:Major trauma often comprises fractures of the thoracolumbar spine and these are often accompanied by relevant thoracic trauma. Major complications can be ascribed to substantial simultaneous trauma to the chest and concomitant immobilization due to spinal instability, pain or neurological dysfunction, impair...
journal_title：Scandinavian journal of trauma, resuscitation and emergency medicine
pub_type： 杂志文章
doi：10.1186/s13049-020-00737-6
更新日期：2020-05-24 00:00:00
abstract：BACKGROUND:The effect of rescue breathing on neurologic prognosis after cardiopulmonary resuscitation (CPR) is controversial. Therefore, we investigated the cerebral microcirculatory and oxygen metabolism during continuous compression (CC) and 30:2 CPR (VC) in a porcine model of cardiac arrest to determine which is bet...
journal_title：Scandinavian journal of trauma, resuscitation and emergency medicine
pub_type： 杂志文章
doi：10.1186/1757-7241-21-55
更新日期：2013-07-12 00:00:00
abstract：BACKGROUND:Severely injured trauma patients are exposed to clinically significant radiation doses from computed tomography (CT) imaging in the emergency department. Moreover, this radiation exposure is associated with an increased risk of cancer. The purpose of this study was to determine some effects of a radiation do...
journal_title：Scandinavian journal of trauma, resuscitation and emergency medicine
pub_type： 杂志文章
doi：10.1186/1757-7241-19-67
更新日期：2011-11-03 00:00:00
abstract：BACKGROUND:A hospital's capacity and preparedness is one of the important parts of disaster planning. Hospital-related incidents, a new phenomenon in Swedish healthcare, may lead to ambulance diversions, increased waiting time at emergency departments and treatment delay along with deterioration of disaster management ...
journal_title：Scandinavian journal of trauma, resuscitation and emergency medicine
pub_type： 杂志文章
doi：10.1186/1757-7241-17-26
更新日期：2009-06-03 00:00:00
abstract：BACKGROUND:Accidental hypothermia increases mortality and morbidity in trauma patients. Various methods for insulating and wrapping hypothermic patients are used worldwide. The aim of this study was to compare the thermal insulating effects and comfort of bubble wrap, ambulance blankets / quilts, and Hibler's method, a...
journal_title：Scandinavian journal of trauma, resuscitation and emergency medicine
pub_type： 杂志文章,随机对照试验
doi：10.1186/1757-7241-19-41
更新日期：2011-06-23 00:00:00
abstract：:The inter-hospital transfer of patients is crucial to a well functioning trauma system, and the transfer process may serve as a quality indicator for regional trauma care. However, the assessment of the transfer process requires high-quality data from various sources. Prospective studies and studies based on single-ce...
journal_title：Scandinavian journal of trauma, resuscitation and emergency medicine
pub_type： 社论
doi：10.1186/1757-7241-18-15
更新日期：2010-03-16 00:00:00
abstract：BACKGROUND:Patients with severe pelvic fractures represent about 3% of all skeletal fractures. Hemodynamic compromise in unstable pelvic fractures is associated with arterial hemorrhage in less than 20% of patients. Angiography is an important tool in the management of severe pelvic injury, but indications and timing f...
journal_title：Scandinavian journal of trauma, resuscitation and emergency medicine
pub_type： 杂志文章
doi：10.1186/1757-7241-17-62
更新日期：2009-11-29 00:00:00
abstract：BACKGROUND:Trauma is a main cause of death among young adults worldwide. Patients experiencing a traumatic cardiac arrest (TCA) certainly have a poor prognosis but population-based studies are sparse. Primarily to describe characteristics and 30-day survival following a TCA as compared with a medical out-of-hospital ca...
journal_title：Scandinavian journal of trauma, resuscitation and emergency medicine
pub_type： 杂志文章
doi：10.1186/s13049-018-0500-7
更新日期：2018-04-23 00:00:00
abstract：BACKGROUND:Educating lay public can significantly strengthen the Chain of Survival after out of hospital cardiac arrest. Schoolchildren are an accessible population for learning basic life support (BLS) and use of an automated external defibrillator (AED) and can be regarded as multipliers of knowledge that can reach t...
journal_title：Scandinavian journal of trauma, resuscitation and emergency medicine
pub_type： 杂志文章
doi：10.1186/s13049-019-0683-6
更新日期：2019-12-23 00:00:00
abstract：BACKGROUND:Some comprehensive cancer centers in industrialized countries have reported improved outcomes in their cardiopulmonary arrest (CPA) patients. Little is known about the outcomes and predictors of CPA in cancer centers in other parts of the world. The objective of this study was to examine the predictors of CP...
journal_title：Scandinavian journal of trauma, resuscitation and emergency medicine
pub_type： 杂志文章
doi：10.1186/1757-7241-21-18
更新日期：2013-03-20 00:00:00
abstract：BACKGROUND:Immediate recognition of stroke symptoms is crucial to ensure timely access to revascularisation therapy. Medical dispatchers ensure fast admission to stroke facilities by prioritising the appropriate medical response. Data on medical dispatchers' ability to recognise symptoms of acute stroke are therefore c...
journal_title：Scandinavian journal of trauma, resuscitation and emergency medicine
pub_type： 杂志文章,随机对照试验
doi：10.1186/s13049-016-0277-5
更新日期：2016-07-07 00:00:00
abstract：BACKGROUND:Major bile leak after blunt liver trauma is rare but challenging. It usually requires endoscopic retrograde cholangiography (ERC) for management. However, there is still lack of specific indications. The aim of this study is to elucidate risk factors for major bile leak and indications for early ERC after bl...
journal_title：Scandinavian journal of trauma, resuscitation and emergency medicine
pub_type： 杂志文章
doi：10.1186/1757-7241-22-26
更新日期：2014-04-15 00:00:00
abstract：BACKGROUND:The municipalities are responsible for the emergency primary health care services in Norway. These services include casualty clinics, primary doctors on-call and local emergency medical communication centres (LEMC). The National centre for emergency primary health care has initiated an enterprise called "The...
journal_title：Scandinavian journal of trauma, resuscitation and emergency medicine
pub_type： 杂志文章
doi：10.1186/1757-7241-17-30
更新日期：2009-07-08 00:00:00
abstract：BACKGROUND:Avalanche rescues mostly rely on helicopter emergency medical services (HEMS) and include technical rescue and complex medical situations under difficult conditions. The adequacy of avalanche victim management has been shown to be unexpectedly low, suggesting the need for quality improvement. We analyse the ...
journal_title：Scandinavian journal of trauma, resuscitation and emergency medicine
pub_type： 杂志文章
doi：10.1186/s13049-018-0520-3
更新日期：2018-07-04 00:00:00
abstract：BACKGROUND:The risk of COVID-19 transmission to healthcare professionals is likely to continue for the foreseeable future. The wearing of personal protective equipment (PPE) presents a number of potential challenges to responders that may impact upon the management of patients in a multi-casualty incident. This report ...
journal_title：Scandinavian journal of trauma, resuscitation and emergency medicine
pub_type： 杂志文章
doi：10.1186/s13049-021-00838-w
更新日期：2021-01-27 00:00:00
abstract：BACKGROUND:In the initial hours after out-of-hospital cardiac arrest (OHCA), it remains difficult to estimate whether the degree of post-ischemic brain damage will be compatible with long-term good neurological outcome. We aimed to construct prognostic models able to predict good neurological outcome of OHCA patients w...
journal_title：Scandinavian journal of trauma, resuscitation and emergency medicine
pub_type： 杂志文章
doi：10.1186/s13049-018-0558-2
更新日期：2018-11-09 00:00:00
abstract：BACKGROUND:The EndoFlex is a new type of tracheal tube with an adjustable distal tip that can be bent without the use of a stylet. The aim of this study was to compare a standard endotracheal tube with the EndoFlex tracheal tube for intubation in patients with simulated cervical spine injury. METHODS:A group of 60 pat...
journal_title：Scandinavian journal of trauma, resuscitation and emergency medicine
pub_type： 杂志文章,随机对照试验
doi：10.1186/1757-7241-21-79
更新日期：2013-11-22 00:00:00
abstract：:This paper describes a simple approach to emergency burr hole evacuation of extra-axial intracranial haematoma that can be used in the uncommon situation when life saving specialist neurosurgical intervention is not available. ...
journal_title：Scandinavian journal of trauma, resuscitation and emergency medicine
pub_type： 社论
doi：10.1186/1757-7241-20-24
更新日期：2012-04-02 00:00:00
abstract：BACKGROUND:The epidemiology of hypotension as presenting symptom among patients in the Emergency Department (ED) is not clarified. The aim of this study was to describe the incidence, etiology, and overall mortality of hypotensive patients in the ED. METHODS:Population-based cohort study at an University Hospital ED i...
journal_title：Scandinavian journal of trauma, resuscitation and emergency medicine
pub_type： 杂志文章
doi：10.1186/s13049-016-0209-4
更新日期：2016-03-02 00:00:00
abstract：BACKGROUND:A national Helicopter Emergency Medical Service (HEMS) was introduced in Denmark in 2014 to ensure the availability of physician-led critical care for all patients regardless of location. Appropriate dispatch of HEMS is known to be complex, and resource utilisation is a highly relevant topic. Population-base...
journal_title：Scandinavian journal of trauma, resuscitation and emergency medicine
pub_type： 杂志文章
doi：10.1186/s13049-019-0672-9
更新日期：2019-11-07 00:00:00
