Natural history of spheno-orbital meningiomas.

Abstract:

BACKGROUND:To investigate the natural history and the growth rate of spheno-orbital meningiomas (SOMs). METHODS:Ninety patients with a diagnosis of SOM were included, and patient charts and imaging were evaluated. In a subset of 32 patients, volumetric studies were performed. RESULTS:The median follow-up for the entire group was 4 years (range, 1-15); the mean age was 47.8 (range, 26-93) years; 94% of the patients were female. The most common clinical signs and symptoms were proptosis (93%), visual deterioration (65%), retro-bulbar pain (23%) and diplopia (6%). In 35% of patients in this series, no visual deterioration occurred, and in 30% only mild proptosis was present. The median annual growth rate of the SOMs in the subset of 32 patients was 0.3 cm³/year (range, 0.03-1.8 cm³/year). We assessed a trend for more rapid tumour growth in younger patients and found the initial volume of the tumour (rho = 0.63) and of the soft tissue component (rho = 074) to be significantly related to the growth rate. CONCLUSION:SOMs are slow-growing tumours that cause primarily proptosis and visual deterioration. In a significant number of patients, these tumours cause minimal discomfort and symptomatology. Therefore, in the absence of risk factors, we advocate a "wait and see" policy. For patients with large SOMs or with a large soft tissue component at first visit or with fast growing SOMs (>1cm³/year), a follow-up examination every 6 months is indicated.

journal_name

Acta Neurochir (Wien)

journal_title

Acta neurochirurgica

authors

Saeed P,van Furth WR,Tanck M,Kooremans F,Freling N,Streekstra GI,Regensburg NI,van der Sprenkel JW,Peerdeman SM,van Overbeeke JJ,Mourits MP

doi

10.1007/s00701-010-0878-0

subject

Has Abstract

pub_date

2011-02-01 00:00:00

pages

395-402

issue

2

eissn

0001-6268

issn

0942-0940

journal_volume

153

pub_type

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