Invasive micropapillary carcinoma of the ampulla of Vater with extensive lymph node metastasis: Report of a case.

Abstract:

:Invasive micropapillary carcinoma is characterized by extensive lymph node metastasis and a poor prognosis. This histological variant was first described in breast cancer, with a few subsequent reports of it in the ampullo-pancreato-biliary region. We report a case of invasive micropapillary carcinoma of the papilla of Vater. A 53-year-old man was admitted to our hospital with signs of obstructive jaundice. Detailed investigations revealed a tumor in the periampullary region, and pancreatoduodenectomy was performed for cancer of the ampulla of Vater. Microscopic examination of the resected specimen revealed a tumor composed mainly of carcinoma cells arranged in micropapillary structures, with extensive regional lymph node metastasis. The patient had an uneventful postoperative course and was followed up in the outpatient clinic. Tumor recurrence with progressive ascites and hydronephrosis was found 8 months after surgery, and the patient died of the disease 20 months after surgery.

journal_name

Surg Today

journal_title

Surgery today

authors

Fujita T,Konishi M,Gotohda N,Takahashi S,Nakagohri T,Kojima M,Kinoshita T

doi

10.1007/s00595-010-4330-0

subject

Has Abstract

pub_date

2010-12-01 00:00:00

pages

1197-200

issue

12

eissn

0941-1291

issn

1436-2813

journal_volume

40

pub_type

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