Abstract:
:Invasive micropapillary carcinoma is characterized by extensive lymph node metastasis and a poor prognosis. This histological variant was first described in breast cancer, with a few subsequent reports of it in the ampullo-pancreato-biliary region. We report a case of invasive micropapillary carcinoma of the papilla of Vater. A 53-year-old man was admitted to our hospital with signs of obstructive jaundice. Detailed investigations revealed a tumor in the periampullary region, and pancreatoduodenectomy was performed for cancer of the ampulla of Vater. Microscopic examination of the resected specimen revealed a tumor composed mainly of carcinoma cells arranged in micropapillary structures, with extensive regional lymph node metastasis. The patient had an uneventful postoperative course and was followed up in the outpatient clinic. Tumor recurrence with progressive ascites and hydronephrosis was found 8 months after surgery, and the patient died of the disease 20 months after surgery.
journal_name
Surg Todayjournal_title
Surgery todayauthors
Fujita T,Konishi M,Gotohda N,Takahashi S,Nakagohri T,Kojima M,Kinoshita Tdoi
10.1007/s00595-010-4330-0subject
Has Abstractpub_date
2010-12-01 00:00:00pages
1197-200issue
12eissn
0941-1291issn
1436-2813journal_volume
40pub_type
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