Abstract:
PURPOSE:The aim of this study was to determine the utility of the peritoneal lavage cytology findings in predicting the clinical outcomes of resectable left-sided pancreatic cancer. METHODS:Peritoneal lavage samples were collected from 39 consecutive patients who underwent surgery for left-sided pancreatic cancer between January 2000 and December 2010. We analyzed the correlations between the peritoneal lavage cytology findings and the clinical outcomes. RESULTS:Five patients (12.8 %) had malignant cells in the cytology samples (positive cytology). This occurred more frequently in patients with vascular invasion (P = 0.008). Positive cytology was significantly associated with lower overall (P = 0.0007) and recurrent-free (P < 0.0001) survival rates. Positive cytology was an independent prognostic factor for recurrence (P = 0.022); it was closely associated with local recurrence, peritoneal recurrence and distant metastasis. CONCLUSION:Surgeons should carefully consider the intraoperative diagnosis of peritoneal lavage cytology in patients with resectable left-sided pancreatic cancers, because patients with positive cytology are likely to experience recurrence.
journal_name
Surg Todayjournal_title
Surgery todayauthors
Iwagami Y,Eguchi H,Wada H,Tomimaru Y,Hama N,Kawamoto K,Kobayashi S,Mori M,Doki Y,Nagano Hdoi
10.1007/s00595-014-0964-7subject
Has Abstractpub_date
2015-04-01 00:00:00pages
444-50issue
4eissn
0941-1291issn
1436-2813journal_volume
45pub_type
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