Diving reflex: can the time course of heart rate reduction be quantified?

Abstract:

:In this meta-analysis of diving bradycardia in humans, we sought to quantify any heart rate (HR) reduction using a relatively simple mathematical function. Using the terms "diving reflex,"diving bradycardia,"diving response,"diving plus heart rate," databases were searched. Data from the studies were fitted using HR=c+aexp(-(t-t(0))/τ), where c is the final HR, a is the HR decrease, τ is the time constant of HR decay, and t(0) is the time delay. Of 890 studies, 220 were given closer scrutiny. Only eight of these provided data obtained under comparable conditions. Apneic facial immersion decreased HR with τ=10.4 s and in air alone it was less pronounced and slower (τ=16.2 s). The exponential function fitted the time course of HR decrease closely (r(2)>0.93). The fit was less adequate for apneic-exercising volunteers. During apnea both with and without face immersion, HR decreases along a monoexponential function with a characteristic time constant. HR decrease during exercise with and without face immersion could not readily be described with a simple function: the parasympathetic reaction was partially offset by some sympathetic activity. Thus, we succeeded in quantifying the early time course of diving bradycardia. It is concluded that the diving reflex is useful to diagnose the integrity of efferent cardiovascular autonomic pathways.

journal_name

Scand J Med Sci Sports

authors

Caspers C,Cleveland S,Schipke JD

doi

10.1111/j.1600-0838.2010.01246.x

subject

Has Abstract

pub_date

2011-02-01 00:00:00

pages

18-31

issue

1

eissn

0905-7188

issn

1600-0838

journal_volume

21

pub_type

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