Small-bowel capsule endoscopy diagnoses early and advanced neoplasms in asymptomatic patients with Lynch syndrome.

Abstract:

BACKGROUND AND STUDY AIMS:Patients with Lynch syndrome are at increased risk of developing small-bowel adenocarcinoma, which usually has a bad prognosis and needs to be diagnosed early. Our aim was to evaluate the yield of capsule endoscopy and CT enteroclysis in this situation. PATIENTS AND METHODS:We performed a prospective, blinded, comparative study of capsule endoscopy and CT enteroclysis in five academic centers. Thirty-five consecutive asymptomatic patients with Lynch syndrome, all with one proven deleterious mutation, were included. A double reading was performed blind for both types of examination. RESULTS:Histologically confirmed small-bowel neoplasms were diagnosed in three patients (8.6 %): one adenocarcinoma (T3N0M0) and two adenomas with low-grade dysplasia. Capsule endoscopy identified all neoplasms. CT enteroclysis raised suspicion of one neoplasm (adenocarcinoma) but missed the two others. Concordance between the two capsule readings was high with a κ value of 0.78 (95 %CI 0.55 to 1.0), which was not the case for CT enteroclysis, where the κ value was 0.15 (95 %CI -0.27 to 0.58). CONCLUSION:Curable early or advanced neoplasms in asymptomatic patients with Lynch syndrome using capsule endoscopy can be detected with a better reproducibility than with CT enteroclysis. The clinical usefulness of systematic small-bowel screening in these patients should be confirmed through large prospective studies.

journal_name

Endoscopy

journal_title

Endoscopy

authors

Saurin JC,Pilleul F,Soussan EB,Manière T,D'Halluin PN,Gaudric M,Cellier C,Heresbach D,Gaudin JL,Capsule Commission of the French Society of Digestive Endoscopy (SFED).

doi

10.1055/s-0030-1255742

subject

Has Abstract

pub_date

2010-12-01 00:00:00

pages

1057-62

issue

12

eissn

0013-726X

issn

1438-8812

journal_volume

42

pub_type

杂志文章
  • Therapeutic endoscopy of the paranasal sinuses.

    abstract::This paper is mainly concerned with describing and demonstrating the technique of paranasal endoscopies--maxillary, frontal, sphenoidal--, illustrated by diagrams. The improvement of technique in diagnosis and therapy of the paranasal sinuses has proved essentially successful. Indications for therapeutic endoscopy of ...

    journal_title:Endoscopy

    pub_type: 杂志文章

    doi:10.1055/s-0028-1098303

    authors: Draf W

    更新日期:1978-11-01 00:00:00

  • Endoscopic removal of an embedded biliary Wallstent by piecemeal extraction.

    abstract::Expandable metal biliary stents are reserved for patients with unresectable malignant biliary obstruction. Occasionally, these stents may cause complications necessitating removal. We describe successful endoscopic removal of a biliary Wallstent one year after insertion in a patient who initially underwent placement o...

    journal_title:Endoscopy

    pub_type: 杂志文章

    doi:10.1055/s-2000-653

    authors: Egan LJ,Baron TH

    更新日期:2000-06-01 00:00:00

  • Video Comment on Jae Jun Park et al.

    abstract:: ...

    journal_title:Endoscopy

    pub_type: 评论,杂志文章

    doi:10.1055/a-0756-1034

    authors:

    更新日期:2018-12-01 00:00:00

  • Endoscopic management of obstructive jaundice due to portal cavernoma.

    abstract::This report describes 2 cases of calcified cavernous transformation of portal vein of unknown etiology. In both cases the revealing symptom was jaundice due to extrinsic compression of the common bile duct by the cavernoma. Only 4 other cases have been previously described in the literature. The cause of the jaundice ...

    journal_title:Endoscopy

    pub_type: 杂志文章

    doi:10.1055/s-2007-1009120

    authors: Thervet L,Faulques B,Pissas A,Bremondy A,Monges B,Salducci J,Grimaud JC

    更新日期:1993-08-01 00:00:00

  • A new endoscopic simulator.

    abstract::Trainees need to perform a certain number of endoscopic procedures to achieve competence. Training on simulators is advantageous because it reduces the number of potentially life-threatening critical mistakes. The change in medical practice that limits education time and patient availability, and the increase in medic...

    journal_title:Endoscopy

    pub_type: 杂志文章

    doi:10.1055/s-2000-8088

    authors: Bar-Meir S

    更新日期:2000-11-01 00:00:00

  • Discrete ulcers in Barrett's esophagus: relationship to acute gastrointestinal bleeding.

    abstract:BACKGROUND AND STUDY AIMS:Although discrete ulcers are a recognized complication of Barrett's esophagus, it is not clear how common discrete ulceration is in Barrett's mucosa. Furthermore, the relationship of gastrointestinal hemorrhage to Barrett's ulceration is unknown. These issues were investigated in this paper. ...

    journal_title:Endoscopy

    pub_type: 杂志文章

    doi:10.1055/s-2007-1001284

    authors: Murphy PP,Ballinger PJ,Massey BT,Shaker R,Hogan WJ

    更新日期:1998-05-01 00:00:00

  • Gastric lipid islands in the gastric stump and in non-operated stomach.

    abstract::The lipid islands in the gastric mucosa are small, well delimited white or yellowish-white patches varying in diameter from 0.5 to 3 millimeters. Microscopically they constitute accumulations of macrophages full of lipids. This endoscopic and histological finding was observed in 0.38% of patients who had not undergone...

    journal_title:Endoscopy

    pub_type: 杂志文章

    doi:10.1055/s-2007-1021711

    authors: Terruzzi V,Minoli G,Butti GC,Rossini A

    更新日期:1980-03-01 00:00:00

  • Development, standardization, and evaluation of NOTES cholecystectomy using a transsigmoid approach in the porcine model: an acute feasibility study.

    abstract:BACKGROUND:Transluminal cholecystectomy is feasible. However, the procedure is time consuming, difficult, and poorly standardized so far. In the present study we therefore aimed to further evaluate and optimize a transsigmoid approach for cholecystectomy with minimal transabdominal assistance in the porcine model. MET...

    journal_title:Endoscopy

    pub_type: 杂志文章

    doi:10.1055/s-2007-966904

    authors: Meining A,Wilhelm D,Burian M,Dundoulakis M,Schneider A,von Delius S,Feussner H

    更新日期:2007-10-01 00:00:00

  • Remote contrast injector in ERCP for protection from X-ray exposure.

    abstract::To protect the assistants from radiation during ERCP, a remote contrast injector employing a lever mechanism (push lever type) was developed. Using this remote injector, safe, finely controlled and easy injection of the contrast material was achieved without X-ray exposure to the assistants in ERCP. ...

    journal_title:Endoscopy

    pub_type: 杂志文章

    doi:10.1055/s-2007-1021616

    authors: Oi I

    更新日期:1982-09-01 00:00:00

  • Botulinum toxin injection as a diagnostic tool for verification of sphincter of Oddi dysfunction causing recurrent pancreatitis.

    abstract::Sphincter of Oddi dyskinesia (SOD) is among the less frequent causes of acute recurrent pancreatitis. We report on a patient with frequent pain attacks accompanied by pancreatic enzyme elevation, in whom a transitory decrease of the SO pressure following endoscopic botulinus toxin injection was a diagnostic clue for S...

    journal_title:Endoscopy

    pub_type: 杂志文章

    doi:10.1055/s-2007-1004086

    authors: Muehldorfer SM,Hahn EG,Ell C

    更新日期:1997-02-01 00:00:00

  • Risk factors for inadequate bowel preparation: a validated predictive score.

    abstract::Background and study aim Inadequate bowel cleansing negatively affects the efficiency of colonoscopy in routine clinical practice. The aim of this study was to design and validate a predictive model for inadequate bowel cleanliness. Patients and methods The model was built from 667 consecutive outpatients (development...

    journal_title:Endoscopy

    pub_type: 杂志文章

    doi:10.1055/s-0043-101683

    authors: Gimeno-García AZ,Baute JL,Hernandez G,Morales D,Gonzalez-Pérez CD,Nicolás-Pérez D,Alarcon-Fernández O,Jiménez A,Hernandez-Guerra M,Romero R,Alonso I,Gonzalez Y,Adrian Z,Carrillo M,Ramos L,Quintero E

    更新日期:2017-06-01 00:00:00

  • Endoscopic management of pancreatic pseudocyst: a long-term follow-up.

    abstract:BACKGROUND AND STUDY AIMS:No studies with real long-term follow-up after endoscopic drainage of pancreatic pseudocysts are available. The present study was undertaken to investigate the long-term outcome of endoscopic management of pancreatic pseudocyst with a minimum follow-up of 2 years. PATIENTS AND METHODS:A total...

    journal_title:Endoscopy

    pub_type: 杂志文章

    doi:10.1055/s-2002-20292

    authors: Sharma SS,Bhargawa N,Govil A

    更新日期:2002-03-01 00:00:00

  • Image manipulation: digital versus analog.

    abstract::A conceptual difference between "analog" and "digital" digitizing is reviewed. Analog and digital type image filing systems are discussed from a comparative point of view: The analog type is advantageous in the number of recordable images, the recording and reproducing speed, and the ability to record a moving picture...

    journal_title:Endoscopy

    pub_type: 杂志文章

    doi:10.1055/s-2007-1010531

    authors: Hattori S

    更新日期:1992-07-01 00:00:00

  • Argon plasma coagulation in the treatment of Barrett's high-grade dysplasia and in situ adenocarcinoma.

    abstract:BACKGROUND AND STUDY AIMS:Endoscopic therapy of high-grade dysplasia (HGD) and superficial adenocarcinoma associated with Barrett's esophagus (BE), using Nd:YAG laser, KTP laser, or photodynamic therapy (PDT), has been reported to be effective in a curative role. Argon plasma coagulation (APC) appears to be effective i...

    journal_title:Endoscopy

    pub_type: 杂志文章

    doi:10.1055/s-2001-12803

    authors: Van Laethem JL,Jagodzinski R,Peny MO,Cremer M,Devière J

    更新日期:2001-03-01 00:00:00

  • Diagnosis and management of iatrogenic endoscopic perforations: European Society of Gastrointestinal Endoscopy (ESGE) Position Statement - Update 2020.

    abstract::1:  ESGE recommends that each center implements a written policy regarding the management of iatrogenic perforations, including the definition of procedures that carry a higher risk of this complication. This policy should be shared with the radiologists and surgeons at each center. 2 : ESGE recommends that in the cas...

    journal_title:Endoscopy

    pub_type: 杂志文章

    doi:10.1055/a-1222-3191

    authors: Paspatis GA,Arvanitakis M,Dumonceau JM,Barthet M,Saunders B,Turino SY,Dhillon A,Fragaki M,Gonzalez JM,Repici A,van Wanrooij RLJ,van Hooft JE

    更新日期:2020-09-01 00:00:00

  • Endoscopic injection of ethanolamine as a treatment for achalasia: a first report.

    abstract:BACKGROUND AND STUDY AIMS:The present study aimed to test the hypothesis that endoscopic sclerotherapy may effectively reduce the occurrence of spasm at the level of the gastric cardia, offering an effective treatment for achalasia. PATIENTS AND METHODS:We prospectively treated 33 achalasia patients by repeated inject...

    journal_title:Endoscopy

    pub_type: 临床试验,杂志文章

    doi:10.1055/s-2007-1005551

    authors: Moretó M,Ojembarrena E,Rodríguez ML

    更新日期:1996-09-01 00:00:00

  • Transcolonoscopic extraperitoneal cecostomy. A new therapeutic and technical proposal.

    abstract::The authors propose a new technique of decompression of the colon consisting in percutaneous cecostomy with previous extraperitonization of the cecum under colonoscopic orientation. The technique permits decompression of the entire colon through the insertion of a ceco-anal multiperforated Levine tube on withdrawing t...

    journal_title:Endoscopy

    pub_type: 杂志文章

    doi:10.1055/s-2007-1018203

    authors: Ganc AJ,Netto AJ,Morrell AC,Plapler H,Ardengh JC

    更新日期:1988-11-01 00:00:00

  • Endoscopic removal of colonic lipoma.

    abstract::A 71-year-old female with symptomatic colonic lipoma is described. An uneventful colonoscopic removal of the lipoma was performed. Colonoscopic removal of symptomatic pedunculated submucosal colonic lipoma may be recommended. ...

    journal_title:Endoscopy

    pub_type: 杂志文章

    doi:10.1055/s-2007-1021668

    authors: Bar-Meir S,Halla A,Baratz M

    更新日期:1981-05-01 00:00:00

  • Comparative study of NOTES rectosigmoidectomy in a swine model: E-NOTES vs. P-NOTES.

    abstract:BACKGROUND AND STUDY AIMS:Several reports have demonstrated the safety of pure natural-orifice transluminal endoscopic surgery (P-NOTES) using transanal endoscopic microsurgery (TEM) and embryonic NOTES (E-NOTES; laparoscopic surgery through the umbilicus). This study was performed to compare the safety and applicabili...

    journal_title:Endoscopy

    pub_type: 杂志文章

    doi:10.1055/s-0030-1256239

    authors: Sohn DK,Jeong SY,Park JW,Kim JS,Hwang JH,Kim DW,Kang SB,Oh JH

    更新日期:2011-06-01 00:00:00

  • Therapeutic pancreatic endoscopy.

    abstract::In view of increasingly accurate noninvasive diagnostic imaging modalities for pancreatic diseases, endoscopic retrograde cholangiopancreatography (ERCP) should be mainly restricted to therapeutic indications. Acute pancreatitis is still the most common complication of ERCP. Prevention measures should focus in particu...

    journal_title:Endoscopy

    pub_type: 杂志文章,评审

    doi:10.1055/s-2004-814119

    authors: Neuhaus H

    更新日期:2004-01-01 00:00:00

  • Perforation of the oesophagus with an oblique--viewing endoscope in a patient with caustic stenosis.

    abstract::A case of accidental oesophageal perforation during endoscopy in an elderly woman with acute alimentary obstruction of a caustic stenosis is presented. This demonstrates the risks in routine use of oblique-viewing endoscopes, especially in oesophageal exploration. The lesion was successfully treated by internal splint...

    journal_title:Endoscopy

    pub_type: 杂志文章

    doi:10.1055/s-0028-1098297

    authors: Starlinger M,Dinstl K,Schiessel R

    更新日期:1978-08-01 00:00:00

  • Endoscopic diagnosis and treatment of upper gastrointestinal tumors.

    abstract::Early diagnosis, endoscopic differentiation of benign from malignant lesions, and removal of clinically significant tumors are increasingly considered to be major topics of interest in the upper gastrointestinal tract. This interest is mainly due to the development of better imaging tools and new resection techniques ...

    journal_title:Endoscopy

    pub_type: 杂志文章,评审

    doi:10.1055/s-0031-1291427

    authors: Deprez PH

    更新日期:2011-11-01 00:00:00

  • Long-term outcome of endoscopic stent placement for chronic pancreatitis associated with pancreas divisum.

    abstract:BACKGROUND AND STUDY AIMS:In pancreas divisum (PD), endoscopic drainage of the minor papilla is beneficial for patients presenting with acute recurrent pancreatitis, but in cases of chronic pancreatitis, surgery is claimed to be indicated. The aim of this study was to evaluate the efficacy of endoscopic stent placement...

    journal_title:Endoscopy

    pub_type: 杂志文章

    doi:10.1055/s-2000-650

    authors: Boerma D,Huibregtse K,Gulik TM,Rauws EA,Obertop H,Gouma DJ

    更新日期:2000-06-01 00:00:00

  • CO2-hysteroscopy today.

    abstract::A survey of intra-uterine endoscopy over the last years is given showing the increased demand for hysteroscopy for diagnosis and therapy of intra-uterine diseases. Its indications include the search for unknown causes of uterine bleeding or sterility. It is also applied for various therapeutic reasons such as for exam...

    journal_title:Endoscopy

    pub_type: 杂志文章

    doi:10.1055/s-0028-1098330

    authors: Lindemann HJ

    更新日期:1979-05-01 00:00:00

  • Endoscopy innovations.

    abstract::Innovation everywhere for everybody - this is the way we can summarize the 2014 Digestive Disease Week, which was held in Chicago, Illinois, last May. Many sessions introduced new innovative materials and concepts. From the robot of the future to the simplest ideas, the congress was fertile and sometimes full of surpr...

    journal_title:Endoscopy

    pub_type: 杂志文章,评审

    doi:10.1055/s-0034-1377510

    authors: Vanbiervliet G,Gonzalez JM,Barthet M

    更新日期:2014-09-01 00:00:00

  • Recurrence of subsquamous dysplasia and carcinoma after successful endoscopic and radiofrequency ablation therapy for dysplastic Barrett's esophagus.

    abstract::Barrett's esophagus with dysplasia is commonly treated with radiofrequency ablation (RFA). Despite its effectiveness, a concern of any ablative technique is the development of subsquamous intestinal metaplasia, which could have potential for future neoplastic progression. To date, 34 cases of subsquamous neoplasia hav...

    journal_title:Endoscopy

    pub_type: 杂志文章

    doi:10.1055/s-0032-1326419

    authors: Lee JK,Cameron RG,Binmoeller KF,Shah JN,Shergill A,Garcia-Kennedy R,Bhat YM

    更新日期:2013-07-01 00:00:00

  • Disinfection procedures of fiberscopes in endoscopy departments.

    abstract::Disinfection of fibre endoscopes was examined in 5 endoscopy departments during endoscopy sessions. On the endoscopes, especially in the instrument channels, Pseudomonas aeruginosa and Proteus species could be regularly found, in some cases also Enterobacter cloacae and Candida albicans. With the results of disinfecti...

    journal_title:Endoscopy

    pub_type: 杂志文章

    doi:10.1055/s-0028-1098370

    authors: Tolon M,Thofern E,Miederer SE

    更新日期:1976-02-01 00:00:00

  • Proctitis with caecitis: an atypical presentation of ulcerative colitis.

    abstract::Ulcerative colitis is characterized as an inflammatory process of the distal colonic mucosa, which may extend proximally. Its proximal extension is classically as a continuous lesion. We describe six patients presenting with typical ulcerative proctiits, who were also found to have an inflammatory area in the caecum, ...

    journal_title:Endoscopy

    pub_type: 杂志文章

    doi:10.1055/s-2002-33239

    authors: Hill MD,Davies G,McIntyre AS,Gorard DA

    更新日期:2002-08-01 00:00:00

  • Comparison of prophylactic clip and endoloop application for the prevention of postpolypectomy bleeding in pedunculated colonic polyps: a prospective, randomized, multicenter study.

    abstract:BACKGROUND AND STUDY AIMS:The effectiveness of the prophylactic clip for the prevention of postpolypectomy bleeding in pedunculated colonic polyps has not been confirmed. The aim of this prospective, randomized study was to compare the efficacy of prophylactic clip and endoloop application in the prevention of postpoly...

    journal_title:Endoscopy

    pub_type: 杂志文章,多中心研究,随机对照试验

    doi:10.1055/s-0034-1365515

    authors: Ji JS,Lee SW,Kim TH,Cho YS,Kim HK,Lee KM,Kim SW,Choi H

    更新日期:2014-07-01 00:00:00

  • Endoscopic ultrasound-guided fine-needle marking of lymph nodes.

    abstract:BACKGROUND AND STUDY AIMS:No previous studies have evaluated the ability of endoscopic ultrasonography to describe the anatomic location of lymph nodes on the basis of a node-to-node comparison. The aim of this study was to assess the feasibility and safety of a new endoscopic ultrasound (EUS)-guided fine-needle techni...

    journal_title:Endoscopy

    pub_type: 杂志文章

    doi:10.1055/s-0029-1215378

    authors: Larsen MH,Fristrup CW,Pless T,Ainsworth AP,Nielsen HO,Hovendal CP,Mortensen MB

    更新日期:2010-02-01 00:00:00