Abstract:
:The Small Integrin-Binding LIgand, N-linked Glycoprotein (SIBLING) family is one category of non-collagenous proteins closely related to osteogenesis. In this study, the authors systematically evaluated the presence and distribution of four SIBLING family members, dentin sialophosphoprotein (DSPP), dentin matrix protein 1 (DMP1), bone sialoprotein (BSP) and osteopontin (OPN), in rat mandibular condylar cartilage using protein chemistry and immunohistochemistry. For protein chemistry, SIBLING proteins in the dissected condylar cartilage were extracted with 4M guanidium-HCl, separated by ion-exchange chromatography, and analyzed by Western immunoblotting. Immunohistochemistry was employed to assess the distribution of these four SIBLING proteins in the condylar cartilage of 2-, 5- and 8-week-old rats. Results from both approaches showed that all four members are expressed in the condylar cartilage. DSPP, unlike that observed in dentin and bone, exists as a full-length form (uncleaved) in the condylar cartilage. The NH(2)-terminal fragment of DMP1 is mainly detected in the matrix of the cartilage while the COOH-terminal fragment is primarily localized in the nuclei of cells in the chondroblastic and hypertrophic layers. The data obtained in this investigation provide clues about the potential roles of these SIBLING proteins in chondrogenesis.
journal_name
Int J Oral Maxillofac Surgjournal_title
International journal of oral and maxillofacial surgeryauthors
Sun Y,Gandhi V,Prasad M,Yu W,Wang X,Zhu Q,Feng JQ,Hinton RJ,Qin Cdoi
10.1016/j.ijom.2009.12.017subject
Has Abstractpub_date
2010-03-01 00:00:00pages
272-81issue
3eissn
0901-5027issn
1399-0020pii
S0901-5027(09)01224-7journal_volume
39pub_type
杂志文章abstract::Micro-computed tomography (microCT) is a new tool to image and quantify trabecular bone. The aim of this study is to compare the two measurement methods when evaluating the early healing of intramembranous (IM) and endochondral (EC) autogenous bone grafts using micro-computed tomography and Q-win computer image analyz...
journal_title:International journal of oral and maxillofacial surgery
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doi:10.1016/j.ijom.2003.09.009
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abstract::The transverse inclination, height and width of 20 lingually placed hydroxylapatite (HA) implants, to augment the atrophic mandibular ridge, were examined using computed tomography of cross sections through the first molar region. Favourable prosthetic conditions are achieved if the HA-implants are placed in a lingual...
journal_title:International journal of oral and maxillofacial surgery
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abstract::Gap arthroplasty, used in the treatment of temporomandibular joint (TMJ) ankylosis, is challenging, requiring resecting of massive abnormal bone formation at the skull base with complex and distorted anatomy. This study evaluated the application of image-guided navigation to gap arthroplasty. Four gap arthroplasties w...
journal_title:International journal of oral and maxillofacial surgery
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abstract::The purpose of this study was to investigate how the characteristics of a poly-l-lactic acid mini-plate changed with dynamic loading in an environment with hydrolytic degradation. A mandible osteosynthesis model was prepared with specimen poly-l-lactic acid mini-plates to simulate sagittal splitting ramus osteotomy. T...
journal_title:International journal of oral and maxillofacial surgery
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journal_title:International journal of oral and maxillofacial surgery
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journal_title:International journal of oral and maxillofacial surgery
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journal_title:International journal of oral and maxillofacial surgery
pub_type: 杂志文章,meta分析,评审
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journal_title:International journal of oral and maxillofacial surgery
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abstract::72 cases of ameloblastoma were obtained from the files of the Department of Pathology, School of Dentistry, Aichi-Gakuin University for the years January 1970 through December 1983. The cases were analyzed with respect to sex, age, duration, site histopathology, and treatment. Of 72 patients, 63 had no previous therap...
journal_title:International journal of oral and maxillofacial surgery
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journal_title:International journal of oral and maxillofacial surgery
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journal_title:International journal of oral and maxillofacial surgery
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journal_title:International journal of oral and maxillofacial surgery
pub_type: 杂志文章
doi:10.1016/j.ijom.2008.09.009
更新日期:2009-02-01 00:00:00
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journal_title:International journal of oral and maxillofacial surgery
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journal_title:International journal of oral and maxillofacial surgery
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journal_title:International journal of oral and maxillofacial surgery
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journal_title:International journal of oral and maxillofacial surgery
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journal_title:International journal of oral and maxillofacial surgery
pub_type: 杂志文章
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journal_title:International journal of oral and maxillofacial surgery
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abstract::Recreating a harmonious gingival contour for contiguous missing teeth in the anterior maxilla is challenging. The aim of this study was to evaluate a split pedicle roll envelope technique designed for pontics. Twelve patients presented a labial flat or concave profile at the implant and pontic sites before second-stag...
journal_title:International journal of oral and maxillofacial surgery
pub_type: 杂志文章
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