Abstract:
:Keloid disease is known to have variable clinical behavior in response to therapy and there is no clinicopathologic classification that predicts such varied behavior. The aim of this study was to study the effect of excision margins and other histopathologic characteristics on keloid prognosis.Seventy-five multiethnic patients presenting with keloid scars at a department of plastic and reconstructive surgery during an 11-year period were included in this study. Clinical data was collected and detailed histologic analyses using light microscopy were carried out on archived patient specimens.A detailed histopathologic examination of all tissue samples identified keloid border or margin characteristics which were classified into "circumscribed" (borders clearly-demarcated) and "infiltrative" (borders not clearly-demarcated and not easily-definable). The specific histologic findings were correlated with keloid recurrence which revealed that incomplete peripheral (P < 0.001) and deep excision margins (P < 0.001), as well as infiltrative borders (P < 0.05) were associated with higher 1-year reported recurrence rates.This study has given evidence that incomplete surgical excision are associated with higher recurrence and this may justify the practice of routine histopathologic reporting of keloid excision margins.
journal_name
Ann Plast Surgjournal_title
Annals of plastic surgeryauthors
Tan KT,Shah N,Pritchard SA,McGrouther DA,Bayat Adoi
10.1097/SAP.0b013e31819b6c3asubject
Has Abstractpub_date
2010-01-01 00:00:00pages
55-8issue
1eissn
0148-7043issn
1536-3708journal_volume
64pub_type
杂志文章abstract::Oxidative stress secondary to ischemia can cause physiopathologic changes that adversely affect wound healing. In this experimental study, we hypothesized that the topical use of esterified glutathione, a well-known antioxidant, can minimize the effects of oxidative stress by an increase in intracellular glutathione a...
journal_title:Annals of plastic surgery
pub_type: 杂志文章
doi:10.1097/01.sap.0000241681.57965.35
更新日期:2007-04-01 00:00:00
abstract::There is general agreement that Dupuytren's contracture is a genetic disorder that occurs predominantly in white men of Northern European ancestry. It appears rarely in the purely black population. We present our experience from Temple University of 8 black patients with Dupuytren's contracture. We also present a revi...
journal_title:Annals of plastic surgery
pub_type: 杂志文章,评审
doi:10.1097/00000637-199406000-00010
更新日期:1994-06-01 00:00:00
abstract::The first reports on gender-confirming surgery had been published in Germany in the 1920s, but it took some 30 years before sex reassignment surgery for transsexuals became generally known. Initially, such surgery was performed mostly in Europe and Casablanca. In 1956, the gynecologist Dr Georges Burou (1910-1987) ind...
journal_title:Annals of plastic surgery
pub_type: 传,历史文章,杂志文章
doi:10.1097/01.sap.0000258974.41516.bc
更新日期:2007-12-01 00:00:00
abstract::The blood supply, venous drainage, and innervation of the lateral skin flap of the leg were studied in 52 fresh specimens by dissection, angiography, and selected injection of cutaneous arteries with india ink. This flap has a long vascular pedicle that contains the peroneal artery and vein and their branches. The dia...
journal_title:Annals of plastic surgery
pub_type: 杂志文章
doi:10.1097/00000637-198510000-00007
更新日期:1985-10-01 00:00:00
abstract::Resection of malignant soft-tissue tumors of the face often results in defects of skin, lining, and contour. When local tissues are unavailable, the folded/multiple skin island forearm free flap has been used to correct complex lining, skin, and contour defects concomitantly. This study is a retrospective review of al...
journal_title:Annals of plastic surgery
pub_type: 杂志文章
doi:10.1097/00000637-200112000-00006
更新日期:2001-12-01 00:00:00
abstract::The transverse rectus abdominis musculocutaneous flap and deep inferior epigastric perforator flap are the flaps of choice for autologous breast reconstruction. The better understanding of the vascular anatomy of these flaps has reduced the incidence of flap loss and fat necrosis, and positioning the flap's least vasc...
journal_title:Annals of plastic surgery
pub_type: 杂志文章
doi:10.1097/01.sap.0000162509.32962.9c
更新日期:2005-06-01 00:00:00
abstract:INTRODUCTION:Transcatheter arterial embolization (TAE) has gained importance in the management of maxillofacial fractures with life-threating hemorrhage (MFH). However, clinical evidence supporting the use of TAE has not been clearly established in the literature. Therefore, we evaluated the effectiveness of TAE for MF...
journal_title:Annals of plastic surgery
pub_type: 杂志文章
doi:10.1097/SAP.0000000000001405
更新日期:2018-06-01 00:00:00
abstract::There are only a few reports that investigate the measurement of functional penile length and compare the methods used for this purpose. The aim of this study was to determine the correlation between the measurement techniques and to determine an appropriate method that correlates the erect state most closely. Measure...
journal_title:Annals of plastic surgery
pub_type: 杂志文章
doi:10.1097/00000637-200204000-00008
更新日期:2002-04-01 00:00:00
abstract:INTRODUCTION:The purpose of this article was to discuss about the use of corticosteroids in head and neck hemangioma as one of the safest noninvasive therapy, focusing on intralesional steroid injection, including perilesional and infusion, for curing or reducing tumor size. METHODS:A systematic review was done by mea...
journal_title:Annals of plastic surgery
pub_type: 杂志文章,评审
doi:10.1097/SAP.0b013e3181d49f52
更新日期:2011-01-01 00:00:00
abstract::We have successfully applied a reverse flow island flap of extensor digitorum brevis muscle for coverage of tissue defects in the distal portion of the foot dorsum in 2 patients. This flap covered the metatarsophalangeal area well with cadaver limb dissection and seems useful to cover the defect in the distal foot dor...
journal_title:Annals of plastic surgery
pub_type: 杂志文章
doi:10.1097/00000637-199207000-00015
更新日期:1992-07-01 00:00:00
abstract::During a 56-month period, 1,348 patients with either basal cell or squamous cell carcinoma of the skin underwent microscopically controlled excision (Mohs' fresh-tissue technique) by a dermatologic surgeon. Of these 1,348 patients, 394 required various types of wound reconstruction by a plastic surgeon. The average di...
journal_title:Annals of plastic surgery
pub_type: 杂志文章
doi:10.1097/00000637-198508000-00003
更新日期:1985-08-01 00:00:00
abstract:UNLABELLED:: Gynecomastia is defined as benign proliferation of glandular breast tissue in men. Gynecomastia causes considerable emotional discomfort because of limitation of everyday activity especially in young men. Surgical treatment of gynecomastia significantly contributes to an increase in social activity and an ...
journal_title:Annals of plastic surgery
pub_type: 杂志文章
doi:10.1097/SAP.0000000000000229
更新日期:2016-06-01 00:00:00
abstract::Reconstruction involving seven venous flaps on six patients was performed. One saphenous venous flap demonstrated partial dermal necrosis; the remaining six survived completely. The largest flap to survive was 5 x 15 cm. Three technical requirements are emphasized; (1) a healthy recipient bed, (2) a donor site with a ...
journal_title:Annals of plastic surgery
pub_type: 杂志文章
doi:10.1097/00000637-199505000-00011
更新日期:1995-05-01 00:00:00
abstract:INTRODUCTION:Plastic surgery training has traditionally been modeled as an "apprenticeship," where faculty teach surgical skills to residents on live patients. Although this is a well-established process, the demand by the public and healthcare agencies for improved patient care, outcomes, and patient safety has led to...
journal_title:Annals of plastic surgery
pub_type: 杂志文章,随机对照试验
doi:10.1097/SAP.0b013e31823b6a1a
更新日期:2012-04-01 00:00:00
abstract:INTRODUCTION:Pyoderma gangrenosum following free tissue transfer for breast reconstruction is rare. This unusual ulcerative condition is frequently misdiagnosed, leading to inappropriate debridement and escalation of the subsequent wound through pathergy. Once diagnosed, treatment with immunosuppressive agents, includi...
journal_title:Annals of plastic surgery
pub_type: 杂志文章
doi:10.1097/SAP.0000000000001782
更新日期:2019-07-01 00:00:00
abstract::Sixteen years ago the result of an operation that was performed on a 5-year-old boy with Romberg's disease was described in this journal. Nineteen years have passed since the first operation, and the authors now report the long-term follow-up. The volume of the transferred free groin flaps was maintained. Although the...
journal_title:Annals of plastic surgery
pub_type: 杂志文章
doi:10.1097/00000637-199812000-00012
更新日期:1998-12-01 00:00:00
abstract::Glomus tumors develop from a thermoregulatory unit called the glomus body which is found in high density within the digits of both the hands and feet. To note, even though less frequently, these tumors can present in extradigital locations. Usually it presents as a small, 1-cm bluish nodule. Glomangioma (multiple glom...
journal_title:Annals of plastic surgery
pub_type: 杂志文章
doi:10.1097/01.sap.0000222729.59856.e1
更新日期:2006-10-01 00:00:00
abstract:BACKGROUND:Patients with unilateral cleft lip and palate (CLP) deformities commonly develop nasal airway obstruction, necessitating septoplasty at the time of definitive rhinoplasty. We assessed the contribution of the bony septum to airway obstruction using computed tomography (CT) and cone beam CT (CBCT). METHODS:A ...
journal_title:Annals of plastic surgery
pub_type: 杂志文章
doi:10.1097/SAP.0000000000000027
更新日期:2015-07-01 00:00:00
abstract::Millions of patients are treated annually in the United States with either acute or chronic wounds, costing billions of dollars. This is a retrospective study designed to quantify the directed education that medical students receive in their 4 years of training on 3 wound-related topics: physiology of tissue injury, p...
journal_title:Annals of plastic surgery
pub_type: 杂志文章
doi:10.1097/SAP.0b013e31802dd43b
更新日期:2007-07-01 00:00:00
abstract::We report a 25-year-old woman who suffered traumatic damage to the medial malleolar area. Arteriography revealed a posterior tibial artery occlusion at the ankle. The predominant pattern of medial soleus vascularization was revealed during surgery. A reverse medial soleus flap including the posterior tibial pedicle wa...
journal_title:Annals of plastic surgery
pub_type: 杂志文章
doi:10.1097/00000637-199810000-00018
更新日期:1998-10-01 00:00:00
abstract:BACKGROUND:Measurement of extremity volume is the most commonly used method for evaluation of lymphedema. However, volumetry would be inappropriate for comparing patients with different physiques, because body-type significantly affects extremity volume. Thus, we cannot evaluate using absolute values. To overcome this ...
journal_title:Annals of plastic surgery
pub_type: 杂志文章
doi:10.1097/SAP.0000000000002505
更新日期:2021-01-01 00:00:00
abstract::The medial sural(MEDIAL GASTROCNEMIUS) perforator flap has previously been described as a free flap distinguished by the potential for a large yet thin cutaneous flap that incorporates the calf skin territory. Its medial sural vascular pedicle can be tailored to allow reach extending from the popliteal fossa to the su...
journal_title:Annals of plastic surgery
pub_type: 杂志文章
doi:10.1097/01.sap.0000116338.59679.12
更新日期:2004-11-01 00:00:00
abstract::The surgical treatments for prominent ears are on the basis of the approach over the basics of the deformity decrease the concha-mastoid angle and create a new antihelical fold. The author describes a new retroauricular flap to be used in the recreation of the antihelical fold and critically analyzes the cosmetic resu...
journal_title:Annals of plastic surgery
pub_type: 杂志文章
doi:10.1097/SAP.0b013e318195bfdd
更新日期:2009-11-01 00:00:00
abstract::A patient affected by a voluminous synovial sarcoma of mediastinum received radical surgery, resulting in injury of both phrenic nerves. Because of the cancer location, reconstruction of the left phrenic nerve was not possible, so to prevent the patient's ventilator dependence, the right phrenic nerve was reconstructe...
journal_title:Annals of plastic surgery
pub_type: 杂志文章
doi:10.1097/SAP.0000000000002543
更新日期:2020-11-01 00:00:00
abstract:BACKGROUND:Equinus deformity is characterized by an abnormal tiptoe gait and does not allow normal walking, hence needing correction. Congenital causes of equinus deformity include neurological diseases such as cerebral palsy and poliomyelitis. Acquired causes include injuries such as extensive trauma. We have correcte...
journal_title:Annals of plastic surgery
pub_type: 杂志文章
doi:10.1097/SAP.0b013e31827a6c83
更新日期:2013-03-01 00:00:00
abstract::The response of tissue to trauma is difficult to define. The zone of injury is an area surrounding a wound that, though traumatized, may not appear nonviable at initial debridement. Because of this, a policy of repeated debridements has been followed to monitor tissues for viability before final tissue coverage. Appre...
journal_title:Annals of plastic surgery
pub_type: 杂志文章,评审
doi:10.1097/SAP.0b013e3181d50e3e
更新日期:2010-12-01 00:00:00
abstract::Reconstruction of the nose after severe burn injury is a challenging problem. There are usually associated facial burns, which limits the availability of local flaps. Reconstruction with unburned distant tissue is often not appropriate because of the resulting mismatch in color and texture. Successful nasal reconstruc...
journal_title:Annals of plastic surgery
pub_type: 杂志文章
doi:10.1097/SAP.0b013e31817d87ed
更新日期:2009-02-01 00:00:00
abstract::Intracompartmental sepsis (IS) is a rare complication in patients with burns. Intracompartmental sepsis presents in patients with inadequate perfusion of intracompartmental tissues and subsequent ischemic necrosis and infection. Contributing factors include high-volume resuscitation, delayed escharotomies, and previou...
journal_title:Annals of plastic surgery
pub_type: 杂志文章
doi:10.1097/SAP.0000000000000691
更新日期:2016-03-01 00:00:00
abstract:OBJECTIVE:Post-burn cicatricle contractures of neck pose a challenge for plastic and reconstructive surgeons. To improve functional and cosmetic results, and to minimize the donor-site morbidity, we use pre-expanded cervico-acromial fasciocutaneous flap based on the supraclavicular artery as a feasible choice for resur...
journal_title:Annals of plastic surgery
pub_type: 杂志文章
doi:10.1097/SAP.0000000000000245
更新日期:2014-09-01 00:00:00
abstract::The use of the nasoalveolar molding technique (NAM) aims to reduce passively the width of the alveolar gap, while improving the AP discrepancy but also focusing on the nose. We developed a within-subjects study in which 11 infants with unilateral lip deformity and varying degrees of alveolar gaps were treated by NAM. ...
journal_title:Annals of plastic surgery
pub_type: 杂志文章
doi:10.1097/01.sap.0000259001.98869.d8
更新日期:2007-11-01 00:00:00