Abstract:
:A fasciocutaneous free graft could prove the ideal free tissue graft to prevent contracture following adhesion of the graft to the recipient bed. However, for graft survival, vascular anastomosis involving complicated surgical techniques is necessary. In the present study, we focused on peripheral blood-derived CD133(+) cells, including the endothelial progenitor cell fraction. The purpose of this study is to investigate whether locally transplanted CD133(+) cells could increase revascularization and improve the quality of free and thick grafted tissue.On the abdomen of nude rats (F344/N Jcl rnu/rnu), a 5 x 2-cm fasciocutaneous graft was designed, which was grafted on to the back. After operation, rats received local injection of 1 x 10(5) human CD133(+) cells resuspended in 400 microL of phosphate-buffered saline (PBS) (CD133(+) group) or the same volume of PBS without cells (control group) (n = 10 in each group). In the CD133(+) group graft perfusion or graft survival was not improved significantly over controls. However, the capillary density increased markedly in the surrounding fascia and the dermis matured at an earlier stage in the CD133(+) group. In this study, we demonstrated that transplanted CD133(+) cells induced new blood vessel growth and improved dermis quality. Cell therapy with CD133(+) cells is already applied in a clinical setting because autologous cells can be used and therefore these procedures are not hampered by ethical concerns. CD133(+) cell transfer therefore has great potential as an adjunct therapy in the realm of microsurgery.
journal_name
Ann Plast Surgjournal_title
Annals of plastic surgeryauthors
Nakanishi M,Ishikawa M,Sunagawa T,Yokota K,Asahara T,Ochi Mdoi
10.1097/SAP.0b013e3181934951subject
Has Abstractpub_date
2009-09-01 00:00:00pages
331-5issue
3eissn
0148-7043issn
1536-3708pii
00000637-200909000-00024journal_volume
63pub_type
杂志文章abstract::Seven male patients and 8 total ears underwent composite excision for neoplasm of the auricular helix. Defect size ranged from 2.5 to 4.5 cm exceeding the conventional limit of l.5 cm for wedge excision with primary closure. An incision at the root of the helix released the superior auricular muscle and a portion of t...
journal_title:Annals of plastic surgery
pub_type: 杂志文章
doi:10.1097/SAP.0b013e3181a395fb
更新日期:2009-05-01 00:00:00
abstract::A prospective study of anatomic variations of the median nerve and its relationship to the surrounding structures was performed of 354 consecutive operations in 192 patients with carpal tunnel syndrome at Korea University Anam Hospital from July 1995 to September 1997. A total of 184 patients were women and 8 patients...
journal_title:Annals of plastic surgery
pub_type: 杂志文章
doi:10.1097/00000637-200044030-00006
更新日期:2000-03-01 00:00:00
abstract::The gastrocnemius muscle flap has gained wide acceptance as a reconstructive technique for management of wounds of the knee and proximal tibia. The use of the muscle as a pedicle flap to the distal and middle femur has not been well quantified, and the proximal rotation arc has been underestimated. We report the use o...
journal_title:Annals of plastic surgery
pub_type: 杂志文章
doi:10.1097/00000637-199504000-00014
更新日期:1995-04-01 00:00:00
abstract::Complete excision of a giant neurofibroma can be technically difficult. Thorough preoperative planning with magnetic resonance imaging, computed tomography, and arteriography are indicated to define the extent of the mass and to facilitate operative planning. By following the treatment guidelines discussed in this cas...
journal_title:Annals of plastic surgery
pub_type: 杂志文章
doi:10.1097/00000637-200045040-00017
更新日期:2000-10-01 00:00:00
abstract:BACKGROUND:Despite a heightened appreciation for wellness in medicine, there exists little information specific to plastic surgery. The purpose of this research was to assess happiness within the field of plastic surgery. METHODS:A cross-sectional study was conducted in July of 2017 by distributing an American Society...
journal_title:Annals of plastic surgery
pub_type: 杂志文章
doi:10.1097/SAP.0000000000002001
更新日期:2020-01-01 00:00:00
abstract:BACKGROUND:Stromal vascular fraction (SVF) cells were used to increase the efficacy of a newly formed adipose tissue in a collagen gel in vitro. However, the outcome of the seeded cells in the collagen gel in vivo remains unknown. We traced the SVF cells in the host tissue and evaluated the efficacy of SVF for fat tiss...
journal_title:Annals of plastic surgery
pub_type: 杂志文章
doi:10.1097/SAP.0000000000000687
更新日期:2016-03-01 00:00:00
abstract::Hematogenous ostemyelitis is infrequently seen in adults and primary involvement of the hand skeleton is extremely rare. Little has been reported about the foci of hematogenously spread infections. Two cases of hematogenous osteomyelitis of the hand originating from dental maxillary infections were reported. The first...
journal_title:Annals of plastic surgery
pub_type: 杂志文章
doi:10.1097/00000637-199607000-00016
更新日期:1996-07-01 00:00:00
abstract::Four cases of unilateral temporomandibular (TM) joint ankylosis were successfully treated by metatarsophalangeal to TM joint replacement by microvascular technique. Results 6 to 20 months postoperatively were encouraging. Further follow-up studies are necessary to evaluate the long-term results. ...
journal_title:Annals of plastic surgery
pub_type: 杂志文章
doi:10.1097/00000637-198512000-00008
更新日期:1985-12-01 00:00:00
abstract::Circumcision is a commonly performed minor surgical procedure; however, it may lead to serious complications if performed by poorly trained health care providers. In this case report, a subglanular stricture causing a mushroom-like deformity resulting from circumcision is presented. ...
journal_title:Annals of plastic surgery
pub_type: 杂志文章
doi:10.1097/01.SAP.0000024754.83430.05
更新日期:2003-02-01 00:00:00
abstract:BACKGROUND:A bilayered artificial dermis is widely applied for skin defects. Its collagen sponge is biodegraded and replaced with dermis-like tissue after application. There is no reliable method for quantitatively evaluating the blood flow of artificial dermis. In this study, we used laser Doppler imaging to evaluate ...
journal_title:Annals of plastic surgery
pub_type: 杂志文章
doi:10.1097/SAP.0b013e3182590948
更新日期:2014-01-01 00:00:00
abstract::The authors present a case where a cross-leg fillet flap from an amputated limb allowed reconstruction of the contralateral disrupted Achilles tendon and provided neurotized soft tissue. Achilles tendon reconstruction of the left leg was achieved by utilizing vascularized extensor tendons from the dorsum of the right ...
journal_title:Annals of plastic surgery
pub_type: 杂志文章
doi:10.1097/SAP.0b013e31802e32d1
更新日期:2007-10-01 00:00:00
abstract:BACKGROUND AND PURPOSE:Extensive orbital floor and medial wall fractures compared with isolated orbital wall fractures are more likely to require surgical correction because of a higher possibility of complications like diplopia, enophthalmos, or numbness. The unique and complex contours of the orbital anatomy limit th...
journal_title:Annals of plastic surgery
pub_type: 杂志文章
doi:10.1097/SAP.0000000000001700
更新日期:2019-01-01 00:00:00
abstract::The authors review 175 basal cell carcinomas of the face, treated primarily by surgery. The overall cure rate was 97%. Among these cases, 53 were treated by excision and immediate local flap reconstruction. Analysis of results in the latter group encourages the use of this method for virgin, untreated tumors provided ...
journal_title:Annals of plastic surgery
pub_type: 杂志文章
doi:
更新日期:1979-07-01 00:00:00
abstract:UNLABELLED:Periprosthetic infections of oncologic reconstructions have an amputation rate between 37% and 87%. Eleven patients with an infected knee reconstruction following limb salvage surgery for cancer were treated with the staged protocol. All patients underwent prosthetic removal and implantation of an antibiotic...
journal_title:Annals of plastic surgery
pub_type: 杂志文章
doi:10.1097/01.sap.0000203990.08414.ad
更新日期:2006-05-01 00:00:00
abstract::After 30 years of clinical use, the 1992 Food and Drug Administration moratorium on silicone gel breast implants (SGBIs) resulted from a paucity of scientific data concerning their safety. The frequency of rupture and reoperative procedures was not known, nor were reliable data available for changes in the physical pr...
journal_title:Annals of plastic surgery
pub_type: 杂志文章,meta分析
doi:10.1097/00000637-200209000-00001
更新日期:2002-09-01 00:00:00
abstract::The authors present their successful experience with an attractive alternative to the latissimus dorsi and gracilis muscle flaps for lower extremity reconstruction--the free rectus abdominis muscle flap. The muscle flap has a dual blood supply, but the longer pedicle length and larger vessel diameter of the inferior e...
journal_title:Annals of plastic surgery
pub_type: 杂志文章
doi:10.1097/00000637-198311000-00003
更新日期:1983-11-01 00:00:00
abstract:BACKGROUND:Tissue expander and implant remains the most common technique for breast reconstruction. A controversial topic within this method is routine use of acellular dermal matrix (ADM). Acellular dermal matrices have increased risks of infection, seroma, hematoma, skin flap necrosis, and total complications. METHO...
journal_title:Annals of plastic surgery
pub_type: 杂志文章
doi:10.1097/SAP.0000000000001322
更新日期:2018-06-01 00:00:00
abstract::Metastatic spread of head and neck cancer signifies a grave change in prognosis for the patient. The presence or absence of detectable metastasis is valuable knowledge both in planning treatment and in predicting prognosis. Knowledge of the metastatic behavior patterns of such tumors, and of the diagnostic means of de...
journal_title:Annals of plastic surgery
pub_type: 杂志文章
doi:10.1097/00000637-198005000-00008
更新日期:1980-05-01 00:00:00
abstract:PURPOSE:The reconstruction of complicated defects with 3-dimensional deficits remains challenging. The reconstruction of these defects requires not only coverage of surface but also appropriate obliteration of dead space, and muscle-chimeric perforator flaps can be a valuable option. Here, we present our experience wit...
journal_title:Annals of plastic surgery
pub_type: 杂志文章
doi:10.1097/SAP.0b013e3182a6363c
更新日期:2015-05-01 00:00:00
abstract::Basal cell carcinoma is the most common type of malignant cutaneous neoplasm found in man. Rarely, however, is it life-threatening or does it metastasize. A review of the literature revealed 138 cases of metastatic basal cell carcinoma. We describe 3 additional patients with metastatic basal cell carcinoma who were tr...
journal_title:Annals of plastic surgery
pub_type: 杂志文章
doi:10.1097/00000637-198312000-00017
更新日期:1983-12-01 00:00:00
abstract:BACKGROUND:Current approaches for the treatment of gingival exposure are often time- and cost-consuming and/or rather invasive. We previously observed a strong correlation between the presence of gingival excess and midfacial depression and here propose an easy 1-step correction technique as a new strategy to improve g...
journal_title:Annals of plastic surgery
pub_type: 杂志文章
doi:10.1097/SAP.0000000000000735
更新日期:2016-12-01 00:00:00
abstract::Surgical procedures commonly associated with parenteral sedation or general anesthesia were completed in an office operating room with local anesthesia and oral medication. Diazepam and alprazolam were used in combination to produce a relaxed state, allowing local anesthesia to be instilled. Surgery was completed succ...
journal_title:Annals of plastic surgery
pub_type: 杂志文章
doi:10.1097/00000637-200044050-00007
更新日期:2000-05-01 00:00:00
abstract::Forearm and wrist injuries can result in a nonfunctional hand caused by loss of motor and sensory functions. Psychological stress is known to accompany traumatic hand injuries and may therefore affect functional outcome. The authors conducted a retrospective study of 107 patients diagnosed with a median, ulnar, or com...
journal_title:Annals of plastic surgery
pub_type: 杂志文章
doi:10.1097/00000637-200207000-00013
更新日期:2002-07-01 00:00:00
abstract::Changes in skin sensibility occur in various postoperative plastic surgeries, especially when they involve major skin and subcutaneous dissection. There were no studies so far that objectively compared changes of ear sensibility. This prospective study was conducted to compare ear sensibility before and after otoplast...
journal_title:Annals of plastic surgery
pub_type: 临床试验,杂志文章
doi:10.1097/SAP.0b013e31820bcc11
更新日期:2012-02-01 00:00:00
abstract::Previous work in our laboratory has indicated that ischemic preconditioning improves musculocutaneous flap survival 2.5 times that of the control flap area when the flaps are subsequently subjected to 4 hours of global ischemia. The preconditioning protocol used in this study was arbitrarily designed to be 10 minutes ...
journal_title:Annals of plastic surgery
pub_type: 杂志文章
doi:10.1097/00000637-199804000-00018
更新日期:1998-04-01 00:00:00
abstract::With a rise in tissue expander-based breast reconstructions (TEBRs) using acellular dermal matrix (ADM), we have seen an increase in ADM-specific complications. In this study, we aimed to evaluate clinically significant seroma (CSS) formation-defined by the need for a drainage procedure-to determine if there was a dif...
journal_title:Annals of plastic surgery
pub_type: 杂志文章
doi:10.1097/SAP.0b013e3182923dc9
更新日期:2013-09-01 00:00:00
abstract:OBJECTIVE:For thin women with little subcutaneous fat and micromastia, they could not obtain ideal results by choosing autologous fat breast augmentation or prosthesis-only breast augmentation. To address these problems, we combined autologous fat and prosthesis for breast augmentation, and the clinical results were sa...
journal_title:Annals of plastic surgery
pub_type: 杂志文章
doi:10.1097/SAP.0000000000002093
更新日期:2019-10-01 00:00:00
abstract::A patient who sustained frontal sinus fracture and who earlier had undergone an osteoplastic fat obliteration procedure is described. The literature is reviewed and recommendations are made for management of this and other cases of frontal sinus fractures with posterior table involvement. ...
journal_title:Annals of plastic surgery
pub_type: 杂志文章,评审
doi:10.1097/00000637-198608000-00012
更新日期:1986-08-01 00:00:00
abstract::A case of long-term survival with metastatic basal cell carcinoma to regional lymph nodes is presented. The literature has been briefly reviewed. When a metastatic basal cell carcinoma is discovered, the average survival is only 8 to 10 months. The patient in this case report has been followed for 10 years from the in...
journal_title:Annals of plastic surgery
pub_type: 杂志文章,评审
doi:10.1097/00000637-199002000-00012
更新日期:1990-02-01 00:00:00
abstract::We describe here 2 patients with question mark ears in one family. They had the peculiar auricular deformities bilaterally. Both patients had a cleft between the helix and earlobe respectively. The upper portion of the auricle showed marked prominence. The mother also showed notching between the helix and earlobe. The...
journal_title:Annals of plastic surgery
pub_type: 杂志文章,评审
doi:10.1097/00000637-198901000-00013
更新日期:1989-01-01 00:00:00