Abstract：
INTRODUCTION:Information extraction (IE) systems have been proposed in recent years to extract genic interactions from bibliographical resources. They are limited to single interaction relations, and have to face a trade-off between recall and precision, by focusing either on specific interactions (for precision), or general and unspecified interactions of biological entities (for recall). Yet, biologists need to process more complex data from literature, in order to study biological pathways. An ontology is an adequate formal representation to model this sophisticated knowledge. However, the tight integration of IE systems and ontologies is still a current research issue, a fortiori with complex ones that go beyond hierarchies. METHOD:We propose a rich modeling of genic interactions with an ontology, and show how it can be used within an IE system. The ontology is seen as a language specifying a normalized representation of text. First, IE is performed by extracting instances from natural language processing (NLP) modules. Then, deductive inferences on the ontology language are completed, and new instances are derived from previously extracted ones. Inference rules are learnt with an inductive logic programming (ILP) algorithm, using the ontology as the hypothesis language, and its instantiation on an annotated corpus as the example language. Learning is set in a multi-class setting to deal with the multiple ontological relations. RESULTS:We validated our approach on an annotated corpus of gene transcription regulations in the Bacillus subtilis bacterium. We reach a global recall of 89.3% and a precision of 89.6%, with high scores for the ten semantic relations defined in the ontology.
journal_name
Int J Med Informjournal_title
International journal of medical informaticsauthors
Manine AP,Alphonse E,Bessières Pdoi
10.1016/j.ijmedinf.2009.03.005subject
Has Abstractpub_date
2009-12-01 00:00:00pages
e31-8issue
12eissn
1386-5056issn
1872-8243pii
S1386-5056(09)00042-2journal_volume
78pub_type
杂志文章abstract：OBJECTIVE:The work proposed a novel bit-rate-reduced approach for reducing the memory required to store a remote diagnosis and rapidly transmission it. METHOD:In the work, an 8x8 Discrete Cosine Transform (DCT) approach is adopted to perform subband decomposition. Modified set partitioning in hierarchical trees (SPIHT...
journal_title：International journal of medical informatics
pub_type： 杂志文章
doi：10.1016/j.ijmedinf.2006.07.002
更新日期：2007-10-01 00:00:00
abstract：OBJECTIVE:To obtain an overview of study designs and study methods used in research evaluating IT in health care, to present a list of quality criteria by which all kinds of reported evaluation studies on IT systems in health care can be assessed, and to assess the quality of reported evaluation studies on IT in health...
journal_title：International journal of medical informatics
pub_type： 杂志文章,评审
doi：10.1016/j.ijmedinf.2006.11.009
更新日期：2008-01-01 00:00:00
abstract：OBJECTIVE:Our aim is to develop reliable descriptions of various seizure types, which will be used as a basis for decision support. We use expert opinions in this process. In this contribution we evaluate the inter-participant agreement in the selection of frequently occurring symptoms for the description of seizure ty...
journal_title：International journal of medical informatics
pub_type： 杂志文章
doi：10.1016/s1386-5056(03)00047-9
更新日期：2003-07-01 00:00:00
abstract：INTRODUCTION:Standard print and verbal information provided to patients undergoing treatments are often difficult to understand and may impair their ability to be truly informed. This study examined the effect of an interactive multimedia informational program with in-line exercises and corrected feedback on patients' ...
journal_title：International journal of medical informatics
pub_type： 杂志文章,随机对照试验
doi：10.1016/j.ijmedinf.2014.01.011
更新日期：2014-05-01 00:00:00
abstract：:To date there have been fewer than a dozen studies on the nature of, and contributory factors in, critical incidents (CI) in anaesthesia. The first of these, by Cooper and colleagues, showed that the vast majority of their CI involved human error [1]. Most recently, the on-going Australian Incident Monitoring Study (A...
journal_title：International journal of medical informatics
pub_type： 杂志文章
doi：10.1016/s1386-5056(97)00087-7
更新日期：1997-11-01 00:00:00
abstract：BACKGROUND:There is an increasing trend in using network science methods and algorithms, including community detection methods, in different areas of healthcare. These areas include protein networks, drug prescriptions, healthcare fraud detection, and drug abuse. Counterfeit drugs, off-label marketing issues, and findi...
journal_title：International journal of medical informatics
pub_type： 杂志文章
doi：10.1016/j.ijmedinf.2020.104161
更新日期：2020-08-01 00:00:00
abstract：OBJECTIVE:Ontology in clinical domains is becoming a core research field in the realm of medical informatics. The objective of this study is to explore the potential role of formal concept analysis (FCA) in a context-based ontology building support in a clinical domain (e.g. cardiovascular medicine here). METHODOLOGY:...
journal_title：International journal of medical informatics
pub_type： 杂志文章
doi：10.1016/s1386-5056(03)00092-3
更新日期：2003-08-01 00:00:00
abstract：OBJECTIVE:The aims of this paper were to study the reporting rate and completeness of data reported from primary healthcare centres (PHCCs) in Sweden to the Swedish National Diabetes Register (NDR), with a special attention on the relation between these measures and the reporting system used by the PHCCs. METHOD:A nat...
journal_title：International journal of medical informatics
pub_type： 杂志文章
doi：10.1016/j.ijmedinf.2011.06.006
更新日期：2011-09-01 00:00:00
abstract：UNLABELLED:This study analyzed patient adoption of secure messaging to update medication list in an ambulatory care setting. The objective was to establish demographic differences between users and non-users of secure messaging for medications list update. Efficiency of secure messaging for the updates was compared to ...
journal_title：International journal of medical informatics
pub_type： 杂志文章
doi：10.1016/j.ijmedinf.2015.06.003
更新日期：2015-10-01 00:00:00
abstract：:In the last years, multidisciplinary post-discharge treatment programs, such as telemonitoring, have been promoted as a strategy for Heart Failure (HF) management. However, the distinctive requirements that a telemonitoring system should have, have not been clearly identified. To this aim, the most relevant requiremen...
journal_title：International journal of medical informatics
pub_type： 杂志文章
doi：10.1016/j.ijmedinf.2020.104204
更新日期：2020-09-01 00:00:00
abstract：OBJECTIVE:Increasingly health care facilities are adopting electronic medical record systems and installing computer workstations in patient exam rooms. The introduction of computer workstations into the medical interview process makes it important to consider the impact of such technology on older patients as well as ...
journal_title：International journal of medical informatics
pub_type： 杂志文章
doi：10.1016/j.ijmedinf.2011.03.005
更新日期：2013-11-01 00:00:00
abstract：:Teleradiology is yet to take off in India. This is unfortunate since this technology is ideal for a country like India, where expertise in remote areas for advanced investigations such as CT and MR, is lacking. We were the first center in India to use teleradiology on a regular basis. Our initial methodology in 1996 w...
journal_title：International journal of medical informatics
pub_type： 杂志文章
doi：10.1016/s1386-5056(01)00138-1
更新日期：2001-05-01 00:00:00
abstract：:To assist medical professional in better treatment of diseases, and improve patient outcomes, healthcare has brought about a cognitive computing revolution. The cognitive computing system processes enormous amounts of data instantly to answer specific queries and makes customized intelligent recommendations. Cognitive...
journal_title：International journal of medical informatics
pub_type： 杂志文章
doi：10.1016/j.ijmedinf.2019.04.024
更新日期：2019-09-01 00:00:00
abstract：:Frequency spectrum of surface electromyographic signals (SEMGs) exhibit a non-stationary nature even in the case of constant level isometric muscle contractions due to changes related to muscle fatigue processes. These changes can be evaluated by methods for estimation of time-varying (TV) spectrum. The most widely ad...
journal_title：International journal of medical informatics
pub_type： 杂志文章
doi：10.1016/s1386-5056(00)00076-9
更新日期：2000-09-01 00:00:00
abstract：BACKGROUND AND OBJECTIVE:Computer aided simulations are useful to support the physician in many steps of the surgical activity, but also in pre-surgical patient classification and in post-surgical diagnosis and treatment decisions. At a broader level, computerized technologies and infrastructures permeate every aspect ...
journal_title：International journal of medical informatics
pub_type： 杂志文章
doi：10.1016/j.ijmedinf.2018.12.008
更新日期：2019-03-01 00:00:00
abstract：BACKGROUND:For more than two decades, Epi Info software has been used to meet the data management, analysis, and mapping needs of public health professionals in more than 181 countries and 13 languages. Until now, most Epi Info systems have been relatively simple, mainly because of a lack of detailed and structured gui...
journal_title：International journal of medical informatics
pub_type： 杂志文章
doi：10.1016/j.ijmedinf.2007.02.001
更新日期：2008-04-01 00:00:00
abstract：OBJECTIVE:To introduce a new concept of medical dashboard system called BESTBoard. Such a system was implemented in all wards in a tertiary academic hospital to explore the development process, core designs, functions, usability and feasibility. METHODS:The task-force team made user interface designs for 6 months base...
journal_title：International journal of medical informatics
pub_type： 杂志文章
doi：10.1016/j.ijmedinf.2016.10.001
更新日期：2017-01-01 00:00:00
abstract：:In this paper, we present a model that describes the stages of the implementation of an information system in a health care organization. The model offers no explanation of the implementation process but rather describes in a cyclic order the domains that are relevant when implementing a system. The model offers thus ...
journal_title：International journal of medical informatics
pub_type： 杂志文章
doi：10.1016/s1386-5056(98)00142-7
更新日期：1998-10-01 00:00:00
abstract：UNLABELLED:The paper provides detailed descriptions of general practitioners (GPs') interactions, both with their computers and their patients, with the aim of facilitating the detailed understanding of how GPs use their computers while in consultation with patients. The focus is on the coordinated activities of the do...
journal_title：International journal of medical informatics
pub_type： 杂志文章
doi：10.1016/j.ijmedinf.2005.04.002
更新日期：2005-07-01 00:00:00
abstract：:The SHARE(1) project (http://www.eu-share.org) was asked to identify the key developments needed to achieve wide adoption and deployment of HealthGrids throughout Europe. The project was asked to organise these as milestones on a road map, so that all technical advances, social actions, economic investments and ethica...
journal_title：International journal of medical informatics
pub_type： 杂志文章
doi：10.1016/j.ijmedinf.2008.10.003
更新日期：2009-04-01 00:00:00
abstract：INTRODUCTION:Appropriate knowledge, correct information, and relevant data are vital in medical diagnosis and treatment systems. Knowledge Management (KM) through its tools/techniques provides a pertinent framework for decision-making in healthcare systems. The objective of this study was to identify and prioritize the...
journal_title：International journal of medical informatics
pub_type： 杂志文章
doi：10.1016/j.ijmedinf.2017.10.012
更新日期：2017-12-01 00:00:00
abstract：:The introduction of computer-based information systems (ISs) in public health provides enhanced possibilities for service improvements and hence also for improvement of the population's health. Not least, new communication systems can help in the socialization and integration process needed between the different profe...
journal_title：International journal of medical informatics
pub_type： 杂志文章
doi：10.1016/s1386-5056(02)00074-6
更新日期：2002-12-18 00:00:00
abstract：OBJECTIVE:The objectives of this paper are: In this approach, the implementation of such a complex IT solution is considered a major redesign of the work system. The paper describes the Human Factor (HF) tasks embedded in the project lifecycle: (1) analysis and modelling of the current work system and usability assessm...
journal_title：International journal of medical informatics
pub_type： 杂志文章
doi：10.1016/j.ijmedinf.2009.07.002
更新日期：2010-04-01 00:00:00
abstract：:This paper reflects some desiderata on the role of Natural Language Processing (NLP) in the coming years as foreseen in the medical domain. During the Medical Informatics Europe (MIE) conference in 1997, the NLP track was composed by numerous papers on natural language, knowledge representation, nomenclatures and clas...
journal_title：International journal of medical informatics
pub_type： 杂志文章
doi：10.1016/s1386-5056(98)00132-4
更新日期：1998-10-01 00:00:00
abstract：:In this paper we describe Tagged Information Management System (TIMS), an integrated knowledge management system for the domain of molecular biology and biomedicine, in which terminology-driven literature mining, knowledge acquisition (KA), knowledge integration (KI), and XML-based knowledge retrieval are combined usi...
journal_title：International journal of medical informatics
pub_type： 杂志文章
doi：10.1016/s1386-5056(02)00055-2
更新日期：2002-12-04 00:00:00
abstract：INTRODUCTION:Unplanned 30-day hospital readmission account for roughly $17 billion in annual Medicare spending. Many factors contribute to unplanned hospital readmissions and multiple models have been developed over the years to predict them. Most researchers have used insurance claims or administrative data to train a...
journal_title：International journal of medical informatics
pub_type： 杂志文章,meta分析,多中心研究
doi：10.1016/j.ijmedinf.2015.09.003
更新日期：2015-12-01 00:00:00
abstract：PURPOSE:Despite the amount of health information available online, there are several barriers that limit the Internet from being adopted as a source of health information. The purpose of this study was to identify individual skill-related problems that users experience when accessing the Internet for health information...
journal_title：International journal of medical informatics
pub_type： 杂志文章
doi：10.1016/j.ijmedinf.2011.10.005
更新日期：2012-01-01 00:00:00
abstract：PURPOSE:Many criteria have been developed to rate the quality of online health information. To effectively evaluate quality, consumers must use quality criteria that can be reliably assessed. However, few instruments have been validated for inter-rater agreement. Therefore, we assessed the degree to which two raters co...
journal_title：International journal of medical informatics
pub_type： 杂志文章
doi：10.1016/j.ijmedinf.2005.02.002
更新日期：2005-08-01 00:00:00
abstract：PURPOSE:The present study evaluated whether an intervention using a short message service (SMS) by personal cellular phone and Internet would reduce cardiovascular risk factors in post-menopausal women with abdominal obesity over 12 weeks. METHODS:This is a quasi-experimental design with pre and post tests. Participan...
journal_title：International journal of medical informatics
pub_type： 杂志文章
doi：10.1016/j.ijmedinf.2011.12.011
更新日期：2012-06-01 00:00:00
abstract：:Effective security arrangements, which both protect and assure those information assets of healthcare providers, doctors and patients, are fundamental requirements in a modern electronic healthcare culture. At the heart of healthcare information systems in future will be those infrastructure components and services, w...
journal_title：International journal of medical informatics
pub_type： 杂志文章
doi：10.1016/s1386-5056(00)00109-x
更新日期：2000-11-01 00:00:00
