Abstract:
BACKGROUND AND STUDY AIMS:Implantation of iodine-125 ( (125)I) seeds under the guidance of endoscopic ultrasonography (EUS) has been proved to be a safe alternative treatment option for advanced pancreatic cancer. The main purpose of this study was to evaluate the feasibility and safety of EUS-guided radiation of the celiac ganglia with (125)I seeds in a porcine model. METHODS:Twelve domestic pigs were randomly divided into three groups. The pigs in group A had blank seeds implanted, and groups B and C had 0.4 mCi and 0.8 mCi (125)I seeds implanted, respectively. Enhanced CT scan and 3-D vascular remodeling were used to check the location of the seeds. All animals were killed and celiac ganglia were checked at 14 and at 60 days after procedure. Necrosis and apoptosis in celiac ganglia and adjacent vessels and organs were also observed. RESULTS:EUS-guided implantations of (125)I seeds in celiac plexus were successful at first procedure in 10 animals. The remaining two animals were implanted successfully the next day. No severe complications occurred in any animal and no damage was found in the surrounding organs. At day 60 after operation, the apoptotic index in the ganglia was 0.53 in the 0.4 mCi group and 0.94 in the 0.8 mCi group. No apoptotic cells were found in the control group implanted with blank seeds. Damage to vessels and surrounding organs by radioactive seeds was observed in only one pig at each time point. CONCLUSION:EUS-guided implantation of (125)I seeds beside the celiac ganglia is a safe procedure and can induce apoptosis of local neurons. This new method may lead to an alternative treatment for pain accompanying pancreatic diseases in human.
journal_name
Endoscopyjournal_title
Endoscopyauthors
Wang K,Jin Z,Du Y,Chen J,Zhan X,Wang L,Li Z,Zou D,Liu Ydoi
10.1055/s-0028-1119588subject
Has Abstractpub_date
2009-04-01 00:00:00pages
346-51issue
4eissn
0013-726Xissn
1438-8812journal_volume
41pub_type
杂志文章相关文献
ENDOSCOPY文献大全abstract::Expandable metal biliary stents are reserved for patients with unresectable malignant biliary obstruction. Occasionally, these stents may cause complications necessitating removal. We describe successful endoscopic removal of a biliary Wallstent one year after insertion in a patient who initially underwent placement o...
journal_title:Endoscopy
pub_type: 杂志文章
doi:10.1055/s-2000-653
更新日期:2000-06-01 00:00:00
abstract::To reduce the risk of complications related to endoscopic submucosal dissection (ESD), we developed a new grasping-type scissors forceps (GSF), which can grasp and incise the targeted tissue using an electrosurgical current. We prospectively evaluated the efficacy and safety of ESD using GSF for the removal of colorec...
journal_title:Endoscopy
pub_type: 杂志文章
doi:10.1055/s-0029-1243973
更新日期:2010-05-01 00:00:00
abstract:BACKGROUND AND STUDY AIMS:The use of sedation in upper gastrointestinal endoscopy is widespread, mainly because of the belief that patients are likely to tolerate the procedure better. The aim of the present study was to assess patients' response to the policy of actively persuading them to accept a throat spray for up...
journal_title:Endoscopy
pub_type: 杂志文章
doi:10.1055/s-2007-1005453
更新日期:1996-03-01 00:00:00
abstract::Ischemic-type biliary lesions (ITBLs) are the most frequent cause of nonanastomotic biliary strictures in liver grafts, affecting about 2-19 % of patients after liver transplantation. ITBL is characterized by bile duct destruction, subsequent stricture formation, and sequestration. We report here the case of a patient...
journal_title:Endoscopy
pub_type: 杂志文章
doi:10.1055/s-2003-40242
更新日期:2003-07-01 00:00:00
abstract::Background and study aims: Gastric reflux into the remnant esophagus after subtotal or partial esophagectomy is associated with impairment in patient quality of life. We evaluated the feasibility, safety, and potential effectiveness of a novel procedure using a new endoscopic suturing device to create an anti-reflux v...
journal_title:Endoscopy
pub_type: 杂志文章
doi:10.1055/s-0042-112572
更新日期:2016-12-01 00:00:00
abstract::A mechanical lithotripter producing a percussion action on biliary stones is described. This device seems to be robust and flexible at the same time. Every biliary stone is easily crushed by this lithotripter. Sixty-seven patients have been endoscopically treated with the aid of this probe. ...
journal_title:Endoscopy
pub_type: 杂志文章
doi:10.1055/s-2007-1018387
更新日期:1986-11-01 00:00:00
abstract::Limited surgery is indicated for mucosal cancer of the esophagus without lymph node metastasis. Esophagectomy without thoracotomy and endoscopic resection are carried out as the operative modalities of reduced surgery. Mucosal cancer less than 3 cm in size without any nodal involvement is suitable for endoscopic resec...
journal_title:Endoscopy
pub_type: 杂志文章
doi:10.1055/s-2007-1010430
更新日期:1993-11-01 00:00:00
abstract::A new method of intragastral disintegration of big blood coagula by mechanical waves is described. Intragastral application of ultrasound was disappointing. A flexural electromagnetic resonator was brought up for clinical trial and showed an effective intragastral thrombotripsy. Even other substances like tablets, foo...
journal_title:Endoscopy
pub_type: 杂志文章
doi:10.1055/s-0028-1098254
更新日期:1978-02-01 00:00:00
abstract:BACKGROUND AND STUDY AIMS:We evaluated the therapeutic effects of percutaneous transhepatic photodynamic therapy (PDT) in patients with advanced bile duct cancer. The utility of intraductal ultrasonography (IDUS) for the assessment of responses and for regular follow up after PDT was also examined. METHODS:Percutaneou...
journal_title:Endoscopy
pub_type: 临床试验,杂志文章
doi:10.1055/s-2005-861294
更新日期:2005-05-01 00:00:00
abstract:BACKGROUND AND STUDY AIMS:Outcomes following surgical treatment of patients with anal fistula are related to eradication of tracts and the internal opening. In this study, the results of surgery based on endoanal ultrasound (EAUS) findings were evaluated. PATIENTS AND METHODS:A total of 102 patients with primary crypt...
journal_title:Endoscopy
pub_type: 杂志文章
doi:10.1055/s-2005-870155
更新日期:2005-08-01 00:00:00
abstract:BACKGROUND AND STUDY AIMS:Oral sodium phosphate (OSP) is a cleansing agent for colonoscopy. Recent reports have cited an increased risk of acute renal failure (ARF) in OSP bowel purgative users, but this risk remains under debate. This study was performed to evaluate the association between OSP and ARF in patients who ...
journal_title:Endoscopy
pub_type: 杂志文章
doi:10.1055/s-0034-1365419
更新日期:2014-06-01 00:00:00
abstract::Trainees need to perform a certain number of endoscopic procedures to achieve competence. Training on simulators is advantageous because it reduces the number of potentially life-threatening critical mistakes. The change in medical practice that limits education time and patient availability, and the increase in medic...
journal_title:Endoscopy
pub_type: 杂志文章
doi:10.1055/s-2000-8088
更新日期:2000-11-01 00:00:00
abstract:BACKGROUND AND STUDY AIMS:An indocyanine green derivative (ICG-sulfo-OSu) that can be used as an infrared fluorescent labeling substance suitable for detecting microlesions with an infrared fluorescence endoscope has been developed. The aims of the present study were to develop an infrared fluorescence endoscope and to...
journal_title:Endoscopy
pub_type: 杂志文章
doi:10.1055/s-2001-17328
更新日期:2001-10-01 00:00:00
abstract::Biliary endoprostheses are increasingly used in the treatment of both benign and malignant pancreaticobiliary disorders. Common bile duct stones are a common clinical problem for which there now exist a range of treatment modalities. Official guidelines in the UK advocate the use of plastic biliary endoprostheses in t...
journal_title:Endoscopy
pub_type: 杂志文章
doi:10.1055/s-0029-1244203
更新日期:2010-09-01 00:00:00
abstract::The majority of choledocholithiasis patients still require surgery. If the stones are removed, the patient is cured. With modern cholangiography, the anatomy and the location of the calculi can be immediately identified at the beginning of the operation. In 6% of cases, anomalies of surgical importance are detected. T...
journal_title:Endoscopy
pub_type: 杂志文章
doi:10.1055/s-2007-1012983
更新日期:1989-12-01 00:00:00
abstract::The electrohydraulic method of crushing bladder stones due to many aforesaid advantages can fully replace mechanical lithotripsy as being both more effective and having little danger of traumas. In rare cases when the stone cannot be crushed with Urat-I its removal should be performed by way of cystomy. ...
journal_title:Endoscopy
pub_type: 杂志文章
doi:10.1055/s-0028-1098477
更新日期:1977-03-01 00:00:00
abstract::Background Participants' experience with a screening test can influence adherence, and therefore the efficacy of screening programs. We compared screening with unsedated flexible sigmoidoscopy and fecal immunochemical testing (FIT) for participants' satisfaction with the decision and for willingness to repeat colorect...
journal_title:Endoscopy
pub_type: 杂志文章,随机对照试验
doi:10.1055/s-0043-117400
更新日期:2017-11-01 00:00:00
abstract::In a prospective series 102 non-variceal upper GI bleeders were studied. An indication for endoscopic injection therapy was seen in 63 patients. In accordance with bleeding intensity, 27 patients were grouped as Forrest Ia, 37 as Forrest Ib, 8 as Forrest II with a "visible vessel" and 13 as Forrest II without one. Def...
journal_title:Endoscopy
pub_type: 杂志文章
doi:10.1055/s-2007-1018481
更新日期:1985-07-01 00:00:00
abstract::A 49-year old severely ill man, with no digestive complaints, was admitted to our hospital. Abdominal ultrasound was suggestive of hepatic metastases. Endoscopy revealed multiple, flat and polypoid, pigmented lesions in the esophagus, stomach and duodenum. Biopsy showed only melanotic pigment, without malignant cells....
journal_title:Endoscopy
pub_type: 杂志文章
doi:10.1055/s-2007-1001373
更新日期:1998-09-01 00:00:00
abstract::A novel disposable transnasal esophagoscope, the E.G. Scan (IntroMedic Co. Ltd., Seoul, Korea), was developed for the evaluation of esophageal diseases while eliminating the inconvenience associated with sterilization, portability, patient monitoring, complications, and the economic burden of sedation. The feasibility...
journal_title:Endoscopy
pub_type: 临床试验,杂志文章
doi:10.1055/s-0031-1291483
更新日期:2012-02-01 00:00:00
abstract:BACKGROUND AND STUDY AIMS:Several endoscopic techniques have been developed to prevent bleeding after the removal of large pedunculated polyps. PATIENTS AND METHODS:From January 1995 to December 2002, 488 consecutive patients with pedunculated colorectal polyps, the heads of which were larger than 10 mm in diameter, w...
journal_title:Endoscopy
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1055/s-2004-825801
更新日期:2004-10-01 00:00:00
abstract::A high proportion of the mortality and morbidity associated with endoscopic procedures may be of cardiopulmonary origin. For this reason, the appropriate degree of monitoring and prophylactic measures to be used in the sedated patient undergoing endoscopy has become a topic of discussion during recent years. The devel...
journal_title:Endoscopy
pub_type: 杂志文章,评审
doi:10.1055/s-2007-1005581
更新日期:1996-10-01 00:00:00
abstract:BACKGROUND AND STUDY AIMS:Many studies have reported on laterally spreading tumors (LSTs), but systematic reviews of the data to determine their risk of containing submucosal invasion (SMI) are lacking. We systematically screened and analyzed the available literature to provide a more solid basis for evidence-based tre...
journal_title:Endoscopy
pub_type: 杂志文章,meta分析
doi:10.1055/s-0043-121144
更新日期:2018-03-01 00:00:00
abstract::Submucosal lymphangiomas are benign tumors which rarely occur in the gastrointestinal tract. The current report describes the tenth case of a submucosal cavernous-cystic lymphangioma of the duodenum. The diagnosis was made during endoscopy and was confirmed histologically in a biopsy specimen. Following a brief review...
journal_title:Endoscopy
pub_type: 杂志文章
doi:10.1055/s-2007-1021740
更新日期:1980-07-01 00:00:00
abstract:BACKGROUND AND STUDY AIM:It is commonly assumed that ablation of any remaining Barrett's epithelium after endoscopic resection of early Barrett's neoplasia improves outcome by reducing the rate of metachronous lesions, but this has not yet been evaluated in a randomized trial. The aim of this study was to compare argon...
journal_title:Endoscopy
pub_type: 杂志文章,随机对照试验
doi:10.1055/s-0033-1358813
更新日期:2014-01-01 00:00:00
abstract::Ulcerative colitis is characterized as an inflammatory process of the distal colonic mucosa, which may extend proximally. Its proximal extension is classically as a continuous lesion. We describe six patients presenting with typical ulcerative proctiits, who were also found to have an inflammatory area in the caecum, ...
journal_title:Endoscopy
pub_type: 杂志文章
doi:10.1055/s-2002-33239
更新日期:2002-08-01 00:00:00
abstract::This report describes 2 cases of calcified cavernous transformation of portal vein of unknown etiology. In both cases the revealing symptom was jaundice due to extrinsic compression of the common bile duct by the cavernoma. Only 4 other cases have been previously described in the literature. The cause of the jaundice ...
journal_title:Endoscopy
pub_type: 杂志文章
doi:10.1055/s-2007-1009120
更新日期:1993-08-01 00:00:00
abstract::Endometrial biopsy was used to study the luteal phase in patients with Fallopian ring (Yoon ring) tubal ligation. Luteal phase insufficiency was found in 9.3% of patients in the study group and in 3.4% of patients in the control group. THe differences are statistically not significant (p = 0.5). The patients with hist...
journal_title:Endoscopy
pub_type: 杂志文章
doi:10.1055/s-2007-1021602
更新日期:1982-07-01 00:00:00
abstract:: ...
journal_title:Endoscopy
pub_type: 杂志文章
doi:10.1055/a-0658-5691
更新日期:2018-12-01 00:00:00
abstract:BACKGROUND AND STUDY AIMS:Double-balloon enteroscopy (DBE) is the first choice endoscopic technique for small-bowel visualization. However, preparation and handling of the double-balloon enteroscope is complex. Recently, a single-balloon enteroscopy (SBE) system has been introduced as being a simplified, less-complex b...
journal_title:Endoscopy
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1055/s-0030-1256247
更新日期:2011-06-01 00:00:00