[PSA and hK2 in the diagnosis of prostate cancer].

Abstract:

:Serum markers for prostate carcinoma are widely applied for the purpose of early detection of cancer and the differentiation between benign and malignant disease, for the pre-treatment staging of detected prostatic cancers, and for the monitoring of prostate cancer after curative or palliative therapies. Since its discovery in 1979, serum PSA has been the most powerful marker of prostate cancer, but, when used alone, PSA is not sufficiently sensitive or specific to consider it an ideal tool for the early detection or staging of prostate cancer. To optimize the use of PSA, the concepts of PSA velocity, PSA density, and age-related PSA values were developed. Moreover, the molecular forms of PSA, especially the percentage of free PSA, seem to be useful tools for the detection of prostate cancer in men with slightly elevated total PSA. Human kallikrein 2 (hK2), a serine protease closely related to PSA that also is expressed predominantly in the prostate, is a new complementary marker to PSA for early detection of prostate cancer. In this review, we examine PSA testing and its effectiveness in the diagnosis of prostate cancer. Further, we also evaluate recent literature regarding the use of hk2.

journal_name

Actas Urol Esp

authors

Alapont Alacreu JM,Navarro Rosales S,Budía Alba A,España Furió F,Morera Martínez F,Jiménez Cruz JF

doi

10.1016/s0210-4806(08)73891-9

subject

Has Abstract

pub_date

2008-06-01 00:00:00

pages

575-88

issue

6

eissn

0210-4806

issn

1699-7980

pii

S0210-4806(08)73891-9

journal_volume

32

pub_type

杂志文章,评审
  • [Shattered kidney in a patient with asymptomatic chronic hydronephrosis. Case report and literature review].

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    journal_title:Actas urologicas espanolas

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    authors: Gómez de Vicente JM,Elices Apellániz M,García Benedito P,Martín Martínez JC,Torronteras Santiago JM

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  • [Superficial carcinoma of the bladder. The pT1 G3 tumor: progression, recurrence, and survival. Treatment].

    abstract::Surface vesical cancer continues to be a problem awaiting to be solved and with an alarmingly increasing incidence. The present report examines the inclusion criteria for the different categories as related to the accepted systems (NMT, Jwet-Marshall) and outlines the significance of the lamina propria invasion in the...

    journal_title:Actas urologicas espanolas

    pub_type: 杂志文章,评审

    doi:

    authors: Nogueira March JL,Ojea Calvo A,Castro Iglesias AM,Rodríguez Iglesias B

    更新日期:1992-10-01 00:00:00

  • [Fournier's gangrene: from urological emergency to plastic surgery].

    abstract::Fournier's gangrene (FG) is a rare and potentially fatal infectious disease characterised by necrotic fasciitis of the perineum and abdominal wall in addition to the scrotum and penis in men and the vulva in women. Skin loss can be very damaging and difficult to repair. This condition must be treated aggressively. Sev...

    journal_title:Actas urologicas espanolas

    pub_type: 杂志文章

    doi:10.1016/s0210-4806(09)72884-0

    authors: Horta R,Cerqueira M,Marques M,Ferreira P,Reis J,Amarante J

    更新日期:2009-09-01 00:00:00

  • Urethral reconstruction in patients previously treated with Memokath™ urethral endoprosthesis.

    abstract:PURPOSE:To evaluate the role and success rate of urethral reconstruction in patients with urethral stricture previously treated with thermos-expandable Memokath™ urethral endoprosthesis. MATERIALS AND METHOD:A case series of patients with urethral stricture and Memokath™ endoprosthesis treated with urethroplasty is pr...

    journal_title:Actas urologicas espanolas

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    doi:10.1016/j.acuro.2018.05.013

    authors: Angulo JC,Pankaj J,Arance I,Kulkarni S

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  • [Papillary cystadenoma of epididymis].

    abstract::Contribution of one case report of papillary cystadenoma, a very uncommon benign epithelial tumour. Related to von Hippel-Lindau's disease, it may be associated to infertility. It tends to occur in young adults, lesions being bilateral in one third of cases. It is diagnosed through palpation and particularly with ultr...

    journal_title:Actas urologicas espanolas

    pub_type: 杂志文章

    doi:10.1016/s0210-4806(00)72541-1

    authors: Peyrí Rey E,Casalots Serramia J

    更新日期:2000-10-01 00:00:00

  • [Urethral amyloidosis].

    abstract::Localized amyloidosis of the urethra is a rare pathological entity. Biopsy is required to make the appropriate diagnosis. Although localized therapy is available for obstructing, symptomatic lesions, asymptomatic lesions may be followed with conservative management and spontaneous regression has been reported. An appr...

    journal_title:Actas urologicas espanolas

    pub_type: 杂志文章

    doi:10.1016/s0210-4806(02)72728-9

    authors: Trívez Boned MA,Blas Marín M,García García MA,Gil Martínez P,García de Jalón Martínez A,Rioja Sanz LA

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  • [Role of electrohydraulic extracorporeal shockwave lithotripsy (Dornier HM 4) in the treatment of caliceal diverticulum lithiasis].

    abstract:UNLABELLED:Caliceal diverticula may be congenital or acquired malformations of the collecting system, normally asymptomatic and discovered during an IVP. Indications for treatment included chronic vague flank pain, acute renal colic, urinary tract infection and hematuria. We present the results of 29 patients with symp...

    journal_title:Actas urologicas espanolas

    pub_type: 临床试验,杂志文章,评审

    doi:

    authors: Torrecilla Ortiz C,Marco Pérez L,Contreras García J,Ponce Campuzano A,Ruíz-Lluch López R,Roig Sanz M,Serrallach Mila N

    更新日期:1998-10-01 00:00:00

  • [Incidence and prevalence of published studies about urolithiasis in Spain. A review].

    abstract:INTRODUCTION:San Antonio, Somacarrera (1977) and Rousaud-Inmark (1984) studies established the first data of incidence and prevalence about urolithiasis in Spain. Other regional or national epidemiologic details were given for several authors from 1977 to 2002. MATERIAL AND METHOD:Sixteen papers with original data abo...

    journal_title:Actas urologicas espanolas

    pub_type: 杂志文章,评审

    doi:10.1016/s0210-4806(07)73675-6

    authors: Sánchez-Martín FM,Millán Rodríguez F,Esquena Fernández S,Segarra Tomás J,Rousaud Barón F,Martínez-Rodríguez R,Villavicencio Mavrich H

    更新日期:2007-05-01 00:00:00

  • [Human chorionic gonadotropin and carcinoembryonic antigen in small cell carcinoma (oat cell) of the urinary bladder].

    abstract::Patient suffering from vesical carcinoma, which is identified as small cells (oat cells) carcinoma. We carried out a histochemical study with H.C.G. and C.E.A. and analyse the results obtained. ...

    journal_title:Actas urologicas espanolas

    pub_type: 杂志文章

    doi:

    authors: Bonet Palau I,Torregrosa Bach MA,Ruiz Romero J,Gotzens García V

    更新日期:1989-11-01 00:00:00

  • [Fibroepithelial polyp of the ureter].

    abstract::Exposition of one case of fibroepithelial polyp of the ureter in a young male patient. The interest of the case lies in the rarity of this entity. Review of all likely etiologies, clinical presentations and differential diagnosis, mainly with malignant tumours whose prognosis and treatment are entirely different. Endo...

    journal_title:Actas urologicas espanolas

    pub_type: 杂志文章

    doi:

    authors: Casanueva Luis T,Benítez Navío J,Laguna Urraca G,López R,Tudela Patón P,Gallardo Galán C

    更新日期:1994-10-01 00:00:00

  • [Penoscrotal gangrene: our series of cases].

    abstract::Ten cases of penoscrotal gangrene seen in our department over the last 8 years are presented. In 80% of patients causative factors of the gangrenous process were demonstrated and were equally distributed between urology and colorectal pathologies. The most commonly associated pathology was diabetes mellitus affecting ...

    journal_title:Actas urologicas espanolas

    pub_type: 杂志文章

    doi:

    authors: Llopis B,Günthner S,Picurelli L,Iranzo S,Moreno F,Ferrer J

    更新日期:1991-01-01 00:00:00

  • [Urothelial carcinoma in a woman with autosomal dominant polycystic kidney disease: description of a case and review of the literature].

    abstract::We describe a case of urothelial carcinoma of renal pelvis in a 48 years old woman affected of autosomal dominant polycystic kidney disease (ADPKD). We discuss the difficulty of the radiological diagnostic and we revise the incidence of renal tumors in this entity. Association between urothelial carcinoma and ADPKD is...

    journal_title:Actas urologicas espanolas

    pub_type: 杂志文章,评审

    doi:10.1016/s0210-4806(07)73784-1

    authors: Arce Terroba Y,Martí T,Villavicencio Mavrich H,De la Torre P,Algaba F

    更新日期:2007-11-01 00:00:00

  • Psychometric validation of the Spanish version of the USS-PROM questionnaire for patients who undergo anterior urethral surgery.

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    journal_title:Actas urologicas espanolas

    pub_type: 杂志文章

    doi:10.1016/j.acuro.2016.01.002

    authors: Puche-Sanz I,Martín-Way D,Flores-Martín J,Expósito-Ruiz M,Vicente-Prados J,Nogueras-Ocaña M,Tinaut-Ranera J,Cózar-Olmo JM

    更新日期:2016-06-01 00:00:00

  • [Granulomatous orchitis].

    abstract::Granulomatous orchitis is an inflammatory change of the testis. This is a rare lesion of unknown etiology. Usually are unilateral. The clinical appearance varies, and it is difficult to differentiate from testicular cancer. The diagnosis usually being made on histological examination after orchiectomy. Our paper repor...

    journal_title:Actas urologicas espanolas

    pub_type: 杂志文章

    doi:10.1016/s0210-4806(00)72526-5

    authors: Calleja Escudero J,de la Cruz Ruíz M,Rivera Ferro J,Torrecilla García-Ripoll JR,Peral Martínez JI,Fernández del Busto E

    更新日期:2000-09-01 00:00:00

  • [Retrocaval ureter in children: surgical approach based on the obstructive pattern in the diuretic renogram with 99mTc DTPA].

    abstract::Retrocaval ureter is a rare disease in childhood which is due to a abnormal development of the inferior cava vein. We report a new case of retrocaval ureter in a 9 year-old girl who had consulted for macrohematuria and right flank pain. Preoperative intravenous urography and DTPA diuretic renogram suggested this entit...

    journal_title:Actas urologicas espanolas

    pub_type: 杂志文章

    doi:

    authors: Méndez Gallart R,Vela Nieto D,Gómez Tellado M,Montero Sánchez M,País Piñeiro E,Candal Alonso J

    更新日期:1998-10-01 00:00:00

  • [Renal transplantation with living donors. A critical analysis of surgical procedures based on 40 years of experience].

    abstract:INTRODUCTION:Absolute priority in an LDKT programme are donnor safety and kidney optimal anatomical and functional preservation. Reduced donnor morbidities, both at short and long term, are important objectives. Excellent technical grafting is a must as are the strategies employed for facilitatig it. We revised the inc...

    journal_title:Actas urologicas espanolas

    pub_type: 杂志文章

    doi:10.1016/s0210-4806(08)73977-9

    authors: Vela Navarrete R,Rodríguez Miñón Cifuentes JL,Calahorra Fernández J,González Enguita C,Cabrera J,García Cardoso JV,Castillon Vela I,Plaza JJ

    更新日期:2008-11-01 00:00:00

  • Extended pelvic lymphadenectomy in patients with clinically localised prostate cancer: A prospective observational study.

    abstract:OBJECTIVE:To determine the frequency of lymph node involvement in patients with clinically localised prostate adenocarcinoma who had radical prostatectomy and extended pelvic lymphadenectomy. MATERIAL AND METHODS:A prospective observational study was conducted on 137 patients with clinically localised prostate cancer ...

    journal_title:Actas urologicas espanolas

    pub_type: 杂志文章,多中心研究

    doi:10.1016/j.acuro.2016.02.002

    authors: Ramos JG,Caicedo JI,Cataño JG,Villarraga LG,Trujillo CG,Robledo D,Plata M

    更新日期:2016-09-01 00:00:00

  • [Bladder tumor lethality. Results in the autonomous community of Rioja between 1975-1991].

    abstract::Between 1975-1991, a total of 557 cases of bladder carcinoma were identified in the Autonomous Community of La Rioja (CAR) which were followed up to December 1994. The overall lethality was 21.9%. 492 cases with 22.35% lethality were identified in males. In females, however, there was 65 cases with 18.46% lethality. T...

    journal_title:Actas urologicas espanolas

    pub_type: 杂志文章

    doi:

    authors: Fernández Fernández A,Gil Fabra J,Fernández Ruíz M,Angulo Castellanos MG,Blanco Martín E,Otero Mauricio G

    更新日期:1998-07-01 00:00:00

  • [Primary adenocarcinoma of the bladder as single tumor. Study of 7 cases and review of the literature].

    abstract::Primary vesical adenocarcinoma is an extremely uncommon tumour, representing 0.5 to 2% of all the urothelial vesical neoplasias. Its behaviour is aggressive and its prognosis poor, especially in the seal ring cell variety. We present our experience in seven cases of vesical adenocarcinoma: one of urachal origin, two o...

    journal_title:Actas urologicas espanolas

    pub_type: 杂志文章,评审

    doi:

    authors: Fernández Fernández A,Maganto Pavón E,Vallejo Herrador J,Escudero Barrilero A

    更新日期:1990-01-01 00:00:00

  • [Adrenal gland myelolipoma. Report of a new case].

    abstract:OBJECTIVE:We report a new case of symptomatic myelolipoma of the adrenal gland. We analyse clinical, diagnostic, histopathologic and therapeutic aspects. METHOD AND RESULTS:Surgical excision was performed by lumbotomy. The patient was asymptomatic after surgery. DISCUSSION:Adrenal myelolipoma is norfunctioning benign...

    journal_title:Actas urologicas espanolas

    pub_type: 杂志文章

    doi:

    authors: Jiménez Calvo J,Fernández Seara P,Grasa Lanau V,Lozano Uruñuela F,De Pablo Cardenas A,Pinos Paul M,Millán Serrano JA,Montesino Semper M

    更新日期:1998-11-01 00:00:00

  • [Trigono-cervico-prostatic incision].

    abstract::Trigone-cervico-prostatic incision is a surgical alternative in the treatment of urinary obstruction induced by small size prostate. Twenty-three patients were treated in our unit with this procedure, 17 because they were carriers of small size prostate and 6 because they were high risk surgical patients in which the ...

    journal_title:Actas urologicas espanolas

    pub_type: 杂志文章

    doi:

    authors: Gil Sanz M,Rioja Sanz C,Romeo Extremar A,Minguez Peman J,Martínez Bengoechea J,Tello Royloa C,Rioja Sanz LA

    更新日期:1992-02-01 00:00:00

  • Risk factors of calculi in upper urinary tract after radical cystectomy with urinary diversion.

    abstract:INTRODUCTION AND OBJECTIVES:The study was conducted to identify the risk factors of upper tract stone formation in patients with diversions after radical cystectomy (RC). MATERIALS AND METHODS:All patients with diversion after RC were collected in our center from January 2005 to December 2013. Three different common d...

    journal_title:Actas urologicas espanolas

    pub_type: 杂志文章

    doi:10.1016/j.acuro.2019.04.002

    authors: Zhang B,Xie H,Liu C

    更新日期:2019-12-01 00:00:00

  • [Iatrogenic foreign bodies. A complication in urologic practice].

    abstract::Report on the presence in 43 patients of various foreign materials left in the urinary tract following a surgical procedure. The clinical symptoms exhibited by these patients correspond to a urinary syndrome with irritation or lumbar pain when the foreign body blocked the upper urinary tract. In most cases, diagnosis ...

    journal_title:Actas urologicas espanolas

    pub_type: 杂志文章,评审

    doi:

    authors: Granados EA,Ríos GJ,Salvador J

    更新日期:1991-09-01 00:00:00

  • Incidence of upper tract urothelial carcinoma in Spain.

    abstract:INTRODUCTION AND OBJECTIVES:The incidence of upper urinary tract tumors is currently unknown. The aim of this study is to determine the real incidence of upper tract urothelial carcinoma (UTUC) in Spain. MATERIAL AND METHODS:A descriptive, prospective and multicenter epidemiological study was conducted in 31 Spanish f...

    journal_title:Actas urologicas espanolas

    pub_type: 杂志文章

    doi:10.1016/j.acuro.2020.03.007

    authors: Fernandez Aparicio T,Galan Llopis JA,Cansino Alcaide R,Pérez Fentes D,Cepeda Delgado M,Alvarez-Ossorio JL,en representación del grupo español EPIUTUC.,Grupo español EPIUTUC.

    更新日期:2020-09-01 00:00:00

  • [Inverted papilloma of the bladder with recurrence in prostatic urethra].

    abstract::Urothelial inverted papilloma is usually a solitary lesion with rare recurrences. Its behaviour is unclear, its potential for recurrence or progression is not well-known. We present a case of inverted papilloma of the bladder with recurrence in prostatic urethra after four years of follow-up. We review etiology, clini...

    journal_title:Actas urologicas espanolas

    pub_type: 杂志文章,评审

    doi:10.1016/s0210-4806(05)73383-0

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    更新日期:2005-11-01 00:00:00

  • Tribulus terrestris versus placebo in the treatment of erectile dysfunction: A prospective, randomized, double blind study.

    abstract:OBJECTIVES:To evaluate the possible effects of Tribulus terrestris herbal medicine in the erectile dysfunction treatment and to quantify its potential impact on serum testosterone levels. DESIGN AND METHODS:Prospective, randomized, double-blind and placebo-controlled study including thirty healthy men selected from 10...

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    pub_type: 杂志文章,随机对照试验

    doi:10.1016/j.acuro.2013.09.014

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    更新日期:2014-05-01 00:00:00

  • [Polymorphisms in inflammatory response genes in metastatic renal cancer].

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    doi:10.1016/s0210-4806(09)74180-4

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  • [Benign presacral schwannoma producing obstructive uropathy. Clinical case and review of the literature].

    abstract::We report a case of a presacral benign schwannoma which causes right hydroureteronephrosis without other clinical findings. After a fine-needle aspiration (FNA) biopsy under computed tomography (CT) guidance, a fusocellular tumour without athypia was demonstrated. With the initial diagnosis of benign schwannoma the pa...

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    pub_type: 杂志文章,评审

    doi:10.1016/s0210-4806(01)72606-x

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    更新日期:2001-03-01 00:00:00

  • [Malignant fibrohistiocytoma of the bladder].

    abstract::We report on new case of a rare vesical tumour. We result the importance of immunohistochemistry and ultrastructural study to support the diagnosis of malignant fibrous histiocytoma of the urinary bladder. There has been described another 16 cases of this tumour in the literature, however, only four of them -five with...

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    pub_type: 杂志文章

    doi:10.1016/j.acuro.2018.01.010

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    更新日期:2018-10-01 00:00:00