A profile of concurrent alcohol and alcohol-interactive prescription drug use in the US population.

Abstract:

BACKGROUND:The risk of adverse events among alcohol-interactive medication users can occur with one standard alcoholic drink. Research on the extent to which this occurs is scant. OBJECTIVE:To examine the prevalence and correlates of concurrent alcohol and alcohol-interactive (AI) medication use across different levels of risk for an alcohol-related adverse event in a nationally representative sample of American adults. METHODS:Cross-sectional analysis of past year, self-reported drinking history as well as past month, self-reported and visually inspected prescription drug use data from the 1999-2000 and 2001-2002 NHANES questionnaire section (n = 8,246). Medications were considered AI if concurrent use of alcohol and the prescription drug could intensify the effects of alcohol, resulting in increased sedation, drowsiness, or dizziness. Weighted prevalence estimates and polytomous logistic regression accounted for the complex survey design. RESULTS:Overall, 13.5% took prescription AI medications, of which 5.6% reported alcohol consumption of three or more drinks on each drinking occasion. Correlates of such use were being a man [adjusted odds ratio (AOR): 4.37; 95% confidence interval (CI): 1.84-10.35], between the ages of 20 and 54 (AOR=12.28; 95% CI: 3.12-48.25), and currently smoking (AOR: 2.61; 95% CI: 1.28-5.29), with alcohol-abstaining AI users as the referent group. CONCLUSIONS:Combining alcohol and AI medications is a common phenomenon, and the risk of alcohol-related adverse drug events may be nontrivial. Screening for alcohol use before prescribing AI medications would be prudent. Better communication regarding the dangers of mixing alcohol with AI medications is warranted.

journal_name

J Gen Intern Med

authors

Jalbert JJ,Quilliam BJ,Lapane KL

doi

10.1007/s11606-008-0639-4

subject

Has Abstract

pub_date

2008-09-01 00:00:00

pages

1318-23

issue

9

eissn

0884-8734

issn

1525-1497

journal_volume

23

pub_type

杂志文章
  • Assessing the Burden of Treatment.

    abstract::Current healthcare systems and guidelines are not designed to adapt to care for the large and growing number of patients with complex care needs and those with multimorbidity. Minimally disruptive medicine (MDM) is an approach to providing care for complex patients that advances patients' goals in health and life whil...

    journal_title:Journal of general internal medicine

    pub_type: 杂志文章,评审

    doi:10.1007/s11606-017-4117-8

    authors: Spencer-Bonilla G,Quiñones AR,Montori VM,International Minimally Disruptive Medicine Workgroup.

    更新日期:2017-10-01 00:00:00

  • Physicians' reasons for failing to comply with computerized preventive care guidelines.

    abstract::The objective of this study was to assess reasons for physicians' noncompliance with computer-generated preventive care reminders. In an academic general internal medicine practice, a survey of physicians' reasons for noncompliance found that 55% of reminders were not complied with. Reasons included "not applicable" i...

    journal_title:Journal of general internal medicine

    pub_type: 杂志文章

    doi:10.1007/BF02599049

    authors: Litzelman DK,Tierney WM

    更新日期:1996-08-01 00:00:00

  • Management of colorectal cancer in Medicare health maintenance organizations.

    abstract::Because of the financial incentives of prepaid care, the quality of care for Medicare enrollees in Health Maintenance Organizations (HMOs) is a concern. Therefore, the care in 150 newly diagnosed cases of colorectal cancer in eight HMOs was compared with that in 180 similar fee-for-service (FFS) cases. As part of the ...

    journal_title:Journal of general internal medicine

    pub_type: 杂志文章

    doi:10.1007/BF02600509

    authors: Retchin SM,Brown B

    更新日期:1990-03-01 00:00:00

  • Brief report: Use and misuse of thyroid ultrasound in the initial workup of patients with suspected thyroid problems referred by primary care physicians to an endocrine clinic.

    abstract:BACKGROUND AND OBJECTIVES:Thyroid ultrasound (TUS) plays an important but limited role in the evaluation of some complaints related to the thyroid gland. This study was designed to examine how primary care physicians use TUS before referring patients to an endocrine clinic. DESIGN:We audited all charts of first-time r...

    journal_title:Journal of general internal medicine

    pub_type: 杂志文章

    doi:10.1111/j.1525-1497.2005.0124.x

    authors: Liel Y,Fraenkel N

    更新日期:2005-08-01 00:00:00

  • Patient-reported racial/ethnic healthcare provider discrimination and medication intensification in the Diabetes Study of Northern California (DISTANCE).

    abstract:BACKGROUND:Racial/ethnic minority patients are more likely to report experiences with discrimination in the healthcare setting, potentially leading to reduced access to appropriate care; however, few studies evaluate reports of discrimination with objectively measured quality of care indicators. OBJECTIVE:To evaluate ...

    journal_title:Journal of general internal medicine

    pub_type: 杂志文章,随机对照试验

    doi:10.1007/s11606-011-1729-2

    authors: Lyles CR,Karter AJ,Young BA,Spigner C,Grembowski D,Schillinger D,Adler N

    更新日期:2011-10-01 00:00:00

  • Presbycusis and communication.

    abstract::Impaired hearing, so common among older people, often has disastrous consequences. The infirmity, too frequently concealed or unknown by the patient, is invisible to others. Disability and frustration can be lessened considerably by greater awareness on the part of medical and lay people about various helpful measures...

    journal_title:Journal of general internal medicine

    pub_type: 杂志文章

    doi:10.1007/BF02596426

    authors: Lipkin M,Williams ME

    更新日期:1986-11-01 00:00:00

  • Development and initial validation of the PEG, a three-item scale assessing pain intensity and interference.

    abstract:BACKGROUND:Inadequate pain assessment is a barrier to appropriate pain management, but single-item "pain screening" provides limited information about chronic pain. Multidimensional pain measures such as the Brief Pain Inventory (BPI) are widely used in pain specialty and research settings, but are impractical for prim...

    journal_title:Journal of general internal medicine

    pub_type: 杂志文章

    doi:10.1007/s11606-009-0981-1

    authors: Krebs EE,Lorenz KA,Bair MJ,Damush TM,Wu J,Sutherland JM,Asch SM,Kroenke K

    更新日期:2009-06-01 00:00:00

  • Surgery for herniated lumbar discs: a literature synthesis.

    abstract:OBJECTIVE:To assess the risks and benefits of surgery for herniated lumbar discs (discectomy) and to evaluate the methodologic quality of the literature. DESIGN:Literature synthesis. STUDY SELECTION AND DATA ANALYSIS: A structured MEDLINE search identified studies of standard, microsurgical, or percutaneous discectomy...

    journal_title:Journal of general internal medicine

    pub_type: 杂志文章,meta分析

    doi:10.1007/BF02600110

    authors: Hoffman RM,Wheeler KJ,Deyo RA

    更新日期:1993-09-01 00:00:00

  • Does affiliation of physician groups with one another produce higher quality primary care?

    abstract:PURPOSE:Recent reports have emphasized the importance of delivery systems in improving health care quality. However, few prior studies have assessed differences in primary care quality between physician groups that differ in size and organizational configuration. We examined whether larger physician group size and affi...

    journal_title:Journal of general internal medicine

    pub_type: 杂志文章

    doi:10.1007/s11606-007-0234-0

    authors: Friedberg MW,Coltin KL,Pearson SD,Kleinman KP,Zheng J,Singer JA,Schneider EC

    更新日期:2007-10-01 00:00:00

  • Physicians, social media, and conflict of interest.

    abstract::Physicians and patients increasingly use social media technologies, such as Facebook, Twitter, and weblogs (blogs), both professionally and personally. Amidst recent reports of physician misbehavior online, as well as concerns about social media's potential negative effect on trust in the medical profession, several n...

    journal_title:Journal of general internal medicine

    pub_type: 杂志文章

    doi:10.1007/s11606-012-2251-x

    authors: Decamp M

    更新日期:2013-02-01 00:00:00

  • Subgroups of High-Cost Medicare Advantage Patients: an Observational Study.

    abstract:BACKGROUND:There is a growing focus on improving the quality and value of health care delivery for high-cost patients. Compared to fee-for-service Medicare, less is known about the clinical composition of high-cost Medicare Advantage populations. OBJECTIVE:To describe a high-cost Medicare Advantage population and iden...

    journal_title:Journal of general internal medicine

    pub_type: 杂志文章

    doi:10.1007/s11606-018-4759-1

    authors: Powers BW,Yan J,Zhu J,Linn KA,Jain SH,Kowalski JL,Navathe AS

    更新日期:2019-02-01 00:00:00

  • VA Provider Perspectives on Coordinating COPD Care Across Health Systems.

    abstract:BACKGROUND:More and more Veterans are receiving care from community providers, increasing the need for effective coordination across health systems. For Veterans with chronic obstructive pulmonary disease (COPD), this need is intensified by complex comorbidity patterns that often include multiple providers co-managing ...

    journal_title:Journal of general internal medicine

    pub_type: 杂志文章,多中心研究

    doi:10.1007/s11606-019-04971-2

    authors: Rinne ST,Resnick K,Wiener RS,Simon SR,Elwy AR

    更新日期:2019-05-01 00:00:00

  • Impact of Project ECHO Models of Medical Tele-Education: a Systematic Review.

    abstract:BACKGROUND:Extension for Community Healthcare Outcomes (ECHO) and related models of medical tele-education are rapidly expanding; however, their effectiveness remains unclear. This systematic review examines the effectiveness of ECHO and ECHO-like medical tele-education models of healthcare delivery in terms of improve...

    journal_title:Journal of general internal medicine

    pub_type: 杂志文章

    doi:10.1007/s11606-019-05291-1

    authors: McBain RK,Sousa JL,Rose AJ,Baxi SM,Faherty LJ,Taplin C,Chappel A,Fischer SH

    更新日期:2019-12-01 00:00:00

  • Understanding African Americans' views of the trustworthiness of physicians.

    abstract:BACKGROUND:Many scholars have written about the historical underpinnings and likely consequences of African Americans distrust in health care, yet little research has been done to understand if and how this distrust affects African Americans' current views of the trustworthiness of physicians. OBJECTIVE:To better unde...

    journal_title:Journal of general internal medicine

    pub_type: 杂志文章,多中心研究

    doi:10.1111/j.1525-1497.2006.00485.x

    authors: Jacobs EA,Rolle I,Ferrans CE,Whitaker EE,Warnecke RB

    更新日期:2006-06-01 00:00:00

  • Individualizing cancer screening in older adults: a narrative review and framework for future research.

    abstract::Older adults often have multiple chronic conditions that may decrease additional life expectancy. Research evaluating the benefits and harms of screening must include consideration of competing morbidities and patient heterogeneity (beyond age), potentially increased harms of screening, and patient preferences. Other ...

    journal_title:Journal of general internal medicine

    pub_type: 杂志文章,评审

    doi:10.1007/s11606-012-2227-x

    authors: Eckstrom E,Feeny DH,Walter LC,Perdue LA,Whitlock EP

    更新日期:2013-02-01 00:00:00

  • A systematic review of qualitative research on the meaning and characteristics of mentoring in academic medicine.

    abstract:BACKGROUND:Mentorship is perceived to play a significant role in the career development and productivity of academic clinicians, but little is known about the characteristics of mentorship. This knowledge would be useful for those developing mentorship programs. OBJECTIVE:To complete a systematic review of the qualita...

    journal_title:Journal of general internal medicine

    pub_type: 杂志文章,评审

    doi:10.1007/s11606-009-1165-8

    authors: Sambunjak D,Straus SE,Marusic A

    更新日期:2010-01-01 00:00:00

  • Genetic testing before anticoagulation? A systematic review of pharmacogenetic dosing of warfarin.

    abstract:BACKGROUND:Genotype-guided initial warfarin dosing may reduce over-anticoagulation and serious bleeding compared to a one-dose-fits-all dosing method. OBJECTIVE:The objective of this review was to investigate the safety and efficacy of genotype-guided dosing of warfarin in reducing the occurrence of serious bleeding e...

    journal_title:Journal of general internal medicine

    pub_type: 杂志文章,评审

    doi:10.1007/s11606-009-0949-1

    authors: Kangelaris KN,Bent S,Nussbaum RL,Garcia DA,Tice JA

    更新日期:2009-05-01 00:00:00

  • Diagnosis in just over a minute: a case of chronic eosinophilic pneumonia.

    abstract::Chronic eosinophilic pneumonia (CEP) is a rare interstitial lung disease characterized by subacute dyspnea, peripheral infiltrates on imaging, and pulmonary eosinophilia. We report a case of a 48-year-old man who presented to a "minute clinic" with cough and dyspnea. After improvement on a short course of steroids for...

    journal_title:Journal of general internal medicine

    pub_type: 杂志文章

    doi:10.1007/s11606-012-2316-x

    authors: Kolb AG,Ives ST,Davies SF

    更新日期:2013-07-01 00:00:00

  • Providing patients web-based data to inform physician choice: if you build it, will they come?

    abstract:BACKGROUND:Despite growing emphasis on public reporting of health care quality data, available data are often ignored. OBJECTIVE:To evaluate the usefulness of web-based physician-level data for patients choosing a new primary care physician (PCP). DESIGN:Patients seeking a new PCP (n = 2225) were invited to view web-...

    journal_title:Journal of general internal medicine

    pub_type: 杂志文章

    doi:10.1007/s11606-007-0278-1

    authors: Fanjiang G,von Glahn T,Chang H,Rogers WH,Safran DG

    更新日期:2007-10-01 00:00:00

  • Using Health Systems Engineering Approaches to Prepare for Tailoring of Implementation Interventions.

    abstract:BACKGROUND:Implementation of evidence-based practices often requires tailoring implementation strategies to local contextual factors, including available resources, expertise, and cultural norms. Using an exemplar case, we describe how health systems engineering methods can be used to understand system-level variation ...

    journal_title:Journal of general internal medicine

    pub_type: 杂志文章

    doi:10.1007/s11606-020-06121-5

    authors: Barnes GD,Acosta J,Kurlander JE,Sales AE

    更新日期:2020-08-31 00:00:00

  • "Stealth" alerts to improve warfarin monitoring when initiating interacting medications.

    abstract:BACKGROUND:As electronic health records (EHRs) become widely adopted, alerts and reminders can improve medication safety, but excessive alerts may irritate or overwhelm clinicians, thereby reducing their effectiveness. We developed a novel "stealth" alert in an EHR to improve anticoagulation monitoring for patients pre...

    journal_title:Journal of general internal medicine

    pub_type: 杂志文章

    doi:10.1007/s11606-012-2137-y

    authors: Koplan KE,Brush AD,Packer MS,Zhang F,Senese MD,Simon SR

    更新日期:2012-12-01 00:00:00

  • Barriers and Facilitators to Real-world Implementation of the Diabetes Prevention Program in Large Healthcare Systems: Lifestyle Coach Perspectives.

    abstract:BACKGROUND:Group-based lifestyle change programs based on the Diabetes Prevention Program (DPP) are associated with clinically significant weight loss and decreases in cardiometabolic risk factors. However, these benefits depend on successful real-world implementation. Studies have examined implementation in community ...

    journal_title:Journal of general internal medicine

    pub_type: 杂志文章

    doi:10.1007/s11606-020-05744-y

    authors: Halley MC,Petersen J,Nasrallah C,Szwerinski N,Romanelli R,Azar KMJ

    更新日期:2020-06-01 00:00:00

  • Extent and determinants of discrepancy between self-evaluations of weight status and clinical standards.

    abstract:OBJECTIVES:To examine the extent and type of discordance between personal and medical classifications of weight status, and to examine the influence of sociodemographic factors on the misclassification of weight status. DESIGN/SETTING:The 1991 Health Promotion and Disease Prevention Supplement of the National Health I...

    journal_title:Journal of general internal medicine

    pub_type: 杂志文章

    doi:10.1046/j.1525-1497.2001.016008538.x

    authors: Chang VW,Christakis NA

    更新日期:2001-08-01 00:00:00

  • Are opioid dependence and methadone maintenance treatment (MMT) documented in the medical record? A patient safety issue.

    abstract:BACKGROUND:Opioid-dependent patients often have co-occurring chronic illnesses requiring medications that interact with methadone. Methadone maintenance treatment (MMT) is typically provided separately from medical care. Hence, coordination of medical care and substance use treatment is important to preserve patient sa...

    journal_title:Journal of general internal medicine

    pub_type: 杂志文章

    doi:10.1007/s11606-009-1043-4

    authors: Walley AY,Farrar D,Cheng DM,Alford DP,Samet JH

    更新日期:2009-09-01 00:00:00

  • Hip fracture: a prospective study of hospital course, complications, and costs.

    abstract::A prospective study of 79 patients with recent hip fracture revealed prior functional impairments with community mobility (49%), using a bathtub (40%), walking outdoors (26%), and stair-climbing (18%). Eighty-six per cent of patients (mean age 77.9 years) were admitted from home, with 95% surviving to discharge but on...

    journal_title:Journal of general internal medicine

    pub_type: 杂志文章

    doi:10.1007/BF02596300

    authors: Campion EW,Jette AM,Cleary PD,Harris BA

    更新日期:1987-03-01 00:00:00

  • A Model of Organizational Context and Shared Decision Making: Application to LGBT Racial and Ethnic Minority Patients.

    abstract::Shared decision making (SDM) occurs when patients and clinicians work together to reach care decisions that are both medically sound and responsive to patients' preferences and values. SDM is an important tenet of patient-centered care that can improve patient outcomes. Patients with multiple minority identities, such...

    journal_title:Journal of general internal medicine

    pub_type: 杂志文章

    doi:10.1007/s11606-016-3608-3

    authors: DeMeester RH,Lopez FY,Moore JE,Cook SC,Chin MH

    更新日期:2016-06-01 00:00:00

  • Can Internet-based continuing medical education improve physicians' skin cancer knowledge and skills?

    abstract::We sought to determine whether an Internet-based continuing medical education (CME) program could improve physician confidence, knowledge, and clinical skills in managing pigmented skin lesions. The CME program provided an interactive, customized learning experience and incorporated well-established guidelines for rec...

    journal_title:Journal of general internal medicine

    pub_type: 杂志文章

    doi:

    authors: Harris JM,Salasche SJ,Harris RB

    更新日期:2001-01-01 00:00:00

  • Impact of Healthcare Delivery System Type on Clinical, Utilization, and Cost Outcomes of Patient-Centered Medical Homes: a Systematic Review.

    abstract:BACKGROUND:As healthcare reimbursement shifts from being volume to value-focused, new delivery models aim to coordinate care and improve quality. The patient-centered medical home (PCMH) model is one such model that aims to deliver coordinated, accessible healthcare to improve outcomes and decrease costs. It is unclear...

    journal_title:Journal of general internal medicine

    pub_type: 杂志文章,评审

    doi:10.1007/s11606-019-05594-3

    authors: Veet CA,Radomski TR,D'Avella C,Hernandez I,Wessel C,Swart ECS,Shrank WH,Parekh N

    更新日期:2020-04-01 00:00:00

  • Academic physicians use placebos in clinical practice and believe in the mind-body connection.

    abstract:BACKGROUND:The placebo and the placebo effect are often investigated in the context of clinical trials. Little data exist on the use of placebos in the course of routine health care. OBJECTIVE:The aim of this study is to describe a group of academic physicians' use of placebos and their knowledge, attitudes, and belie...

    journal_title:Journal of general internal medicine

    pub_type: 杂志文章

    doi:10.1007/s11606-007-0332-z

    authors: Sherman R,Hickner J

    更新日期:2008-01-01 00:00:00

  • Harnessing the Power of Hospitalists in Operational Disaster Planning: COVID-19.

    abstract::Hospitalists are well poised to serve in key leadership roles and in frontline care in particular when facing a pandemic such as the SARS-CoV-2 (COVID-19) infection. Much of the disaster planning in hospitals around the country addresses overcrowded emergency departments and decompressing these locations; however, in ...

    journal_title:Journal of general internal medicine

    pub_type: 杂志文章,评审

    doi:10.1007/s11606-020-05952-6

    authors: Bowden K,Burnham EL,Keniston A,Levin D,Limes J,Persoff J,Thurman L,Burden M

    更新日期:2020-09-01 00:00:00