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Canine behavioral genetics: pointing out the phenotypes and herding up the genes.

Abstract：

:An astonishing amount of behavioral variation is captured within the more than 350 breeds of dog recognized worldwide. Inherent in observations of dog behavior is the notion that much of what is observed is breed specific and will persist, even in the absence of training or motivation. Thus, herding, pointing, tracking, hunting, and so forth are likely to be controlled, at least in part, at the genetic level. Recent studies in canine genetics suggest that small numbers of genes control major morphologic phenotypes. By extension, we hypothesize that at least some canine behaviors will also be controlled by small numbers of genes that can be readily mapped. In this review, we describe our current understanding of a representative subset of canine behaviors, as well as approaches for phenotyping, genome-wide scans, and data analysis. Finally, we discuss the applicability of studies of canine behavior to human genetics.

journal_name

Am J Hum Genet

journal_title

American journal of human genetics

authors

Spady TC,Ostrander EA

doi

10.1016/j.ajhg.2007.12.001

subject

Has Abstract

pub_date

2008-01-01 00:00:00

pages

10-8

issue

1

eissn

0002-9297

issn

1537-6605

pii

S0002-9297(07)00027-4

journal_volume

82

pub_type

杂志文章,评审

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