Catheter-directed thrombolysis of inferior vena cava thrombosis in a 13-day-old neonate and review of literature.

Abstract:

:Complete inferior vena cava thrombosis (IVC) in neonates is uncommon, but may cause significant morbidity. A 13-day-old neonate suffered IVC thrombosis secondary to antithrombin III deficiency, possibly contributed to by a mutation in the methyl tetrahydrofolate reductase gene. Catheter-directed thrombolysis (CDT) with recombinant tissue plasminogen activator (rt-PA, Alteplase) was used successfully to treat extensive venous thrombosis in this neonate without complications. We also review the literature on CDT for treatment of IVC thrombosis in critically ill neonates and infants.

authors

Khan JU,Takemoto CM,Casella JF,Streiff MB,Nwankwo IJ,Kim HS

doi

10.1007/s00270-007-9229-9

subject

Has Abstract

pub_date

2008-07-01 00:00:00

pages

S153-60

eissn

0174-1551

issn

1432-086X

journal_volume

31 Suppl 2

pub_type

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