Abstract:
:The discovery of the genetic code was one of the most important advances of modern biology. But there is more to a DNA code than protein sequence; DNA carries signals for splicing, localization, folding, and regulation that are often embedded within the protein-coding sequence. In this issue, Itzkovitz and Alon show that the specific 64-to-20 mapping found in the genetic code may have been optimized for permitting protein-coding regions to carry this extra information and suggest that this property may have evolved as a side benefit of selection to minimize the negative effects of frameshift errors.
journal_name
Genome Resjournal_title
Genome researchauthors
Bollenbach T,Vetsigian K,Kishony Rdoi
10.1101/gr.6144007subject
Has Abstractpub_date
2007-04-01 00:00:00pages
401-4issue
4eissn
1088-9051issn
1549-5469pii
gr.6144007journal_volume
17pub_type
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