Rhinocerebral zygomycosis in a young girl undergoing allogeneic stem cell transplantation for severe aplastic anaemia.

Abstract:

:We report on a 10-year-old girl with severe aplastic anaemia who developed rhinocerebral infection caused by Absidia corymbifera and a possible co-infection caused by Alternaria alternata. Despite prolonged neutropenia, therapy with liposomal amphotericin B and posaconazole improved the clinical condition. Subsequently, the girl underwent allogeneic haematopoietic stem cell transplantation (HSCT) for the underlying disease, but the fungal infection remained under control with the antifungal treatment. No severe side effect of the antifungal drugs was noted. Unfortunately, the girl died 5 months after HSCT due to disseminated adenovirus infection.

journal_name

Mycoses

journal_title

Mycoses

authors

Sörensen J,Becker M,Porto L,Lambrecht E,Schuster T,Beske F,Rickerts V,Klingebiel T,Lehrnbecher T

doi

10.1111/j.1439-0507.2006.01300.x

subject

Has Abstract

pub_date

2006-01-01 00:00:00

pages

31-6

eissn

0933-7407

issn

1439-0507

pii

MYC1300

journal_volume

49 Suppl 1

pub_type

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