Abstract:
INTRODUCTION:Although in the pharmacological field topiramate has shown proved efficacy in impulsive behavioral disorders (IBD), this fact has not been demonstrated with the same evidence in children and adolescents. The aim of this study is to evaluate improvement of symptoms in different IBD in those ages after treatment with topiramate. CLINICAL CASE:Eleven cases of IBD (DSM-IV criteria) were evaluated with the Barrat Impulsivity Scale (BIS), obtaining scores at zero, one and three months after starting treatment with topiramate. RESULTS:We found significant differences in the cognitive impulsivity subscale (p=0.040) and total score of the BIS (p=0.043) when BIS scale was measured after one month of treatment; after three months of treatment, the motor impulsivity subscale also showed significant differences (p=0.015). CONCLUSIONS:The significant reductions at BIS scores in child and adolescents outpatients who have IBD make us consider topiramate as an effective pharmacological option for treatment of impulsivity in several psychiatric disorders, also in childhood and adolescence. More studies are needed to confirm these results, with bigger samples and control groups.
journal_name
Actas Esp Psiquiatrjournal_title
Actas espanolas de psiquiatriaauthors
Dolengevich Segal H,Rodríguez Salgado B,Conejo Garcia A,San Sebastian Cabases Jsubject
Has Abstractpub_date
2006-07-01 00:00:00pages
280-2issue
4eissn
1139-9287issn
1578-2735pii
611104111journal_volume
34pub_type
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journal_title:Actas espanolas de psiquiatria
pub_type: 杂志文章,评审
doi:
更新日期:2001-03-01 00:00:00
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doi:
更新日期:2014-11-01 00:00:00
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journal_title:Actas espanolas de psiquiatria
pub_type: 杂志文章
doi:
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journal_title:Actas espanolas de psiquiatria
pub_type: 杂志文章
doi:
更新日期:2004-11-01 00:00:00
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pub_type: 杂志文章
doi:
更新日期:2001-11-01 00:00:00
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doi:
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pub_type: 杂志文章,评审
doi:
更新日期:2000-09-01 00:00:00
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pub_type: 杂志文章,随机对照试验
doi:
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doi:
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journal_title:Actas espanolas de psiquiatria
pub_type: 杂志文章
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pub_type: 杂志文章
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pub_type: 杂志文章
doi:
更新日期:2000-01-01 00:00:00
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doi:
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