Randomized placebo-controlled trial of oral liquid simethicone prior to upper gastrointestinal endoscopy.

Abstract:

:It has been suggested that pre-procedural oral simethicone improves visibility in upper GI tract endoscopy. We examined three-hundred-thirty patients referred for upper endoscopy who were randomized and were required to swallow a placebo solution or one of three liquid simethicone solutions 15 min prior to the examination. These solutions contained 65 mg, 65 mg and 195 mg of drug dissolved in 90 ml, 30 ml and 90 ml of water, respectively. Patients treated with both dosages of simethicone revealed significantly less foam and bubbles in both the stomach and the duodenum compared to placebo. Only the 90 ml volume adequately cleared both locations. The reduction of examination time could be found both in patients with an intact stomach and in patients with or without gastric bile reflux, but was most striking in patients with previous gastric resection (examination time being reduced by almost 50% and the need of adjunctive lavage being reduced about 20 fold compared to placebo). In conclusion, pre-procedural oral simethicone should be routinely considered in patients with previous gastric resection. The utility of the drug is less evident in patients with normal gastric anatomy.

journal_name

Endoscopy

journal_title

Endoscopy

authors

Bertoni G,Gumina C,Conigliaro R,Ricci E,Staffetti J,Mortilla MG,Pacchione D

doi

10.1055/s-2007-1010479

subject

Has Abstract

pub_date

1992-05-01 00:00:00

pages

268-70

issue

4

eissn

0013-726X

issn

1438-8812

journal_volume

24

pub_type

临床试验,杂志文章,随机对照试验
  • Endoscopic injection of ethanolamine as a treatment for achalasia: a first report.

    abstract:BACKGROUND AND STUDY AIMS:The present study aimed to test the hypothesis that endoscopic sclerotherapy may effectively reduce the occurrence of spasm at the level of the gastric cardia, offering an effective treatment for achalasia. PATIENTS AND METHODS:We prospectively treated 33 achalasia patients by repeated inject...

    journal_title:Endoscopy

    pub_type: 临床试验,杂志文章

    doi:10.1055/s-2007-1005551

    authors: Moretó M,Ojembarrena E,Rodríguez ML

    更新日期:1996-09-01 00:00:00

  • Endoscopic treatment of nonstricture-related benign biliary diseases using covered self-expandable metal stents.

    abstract:BACKGROUND AND STUDY AIMS:Nonstricture benign biliary diseases (BBDs) such as leaks, perforations, and bleeding, have been traditionally managed by placement of one or more plastic stents. Emerging data support the use of covered, self-expandable, metal stents (CSEMSs). The aim of this study was to assess the outcomes ...

    journal_title:Endoscopy

    pub_type: 杂志文章

    doi:10.1055/s-0034-1391093

    authors: Irani S,Baron TH,Law R,Akbar A,Ross AS,Gluck M,Gan I,Kozarek RA

    更新日期:2015-04-01 00:00:00

  • Conservative management of colonoscopic perforation can be misleading.

    abstract::The management of colonoscopic perforations is still evolving. Many now agree to the selective management strategy: Perforations during diagnostic colonoscopy being treated surgically and therapeutic ones treated conservatively. However, patients with diagnostic perforation, if they have clean bowel and no signs of pe...

    journal_title:Endoscopy

    pub_type: 杂志文章

    doi:10.1055/s-2007-1001423

    authors: Soliman A,Grundman M

    更新日期:1998-11-01 00:00:00

  • The spiral enteroscopy training initiative: results of a prospective study evaluating the Discovery SB overtube device during small bowel enteroscopy (with video).

    abstract:BACKGROUND AND AIM:Indications for small-bowel enteroscopy are increasing, but advancing the endoscope to the ileum remains challenging, especially for less experienced operators. The aim was to evaluate the ease of use, safety, and efficacy of the Discovery SB overtube (Spirus Medical, Stoughton, Massachusetts, USA) d...

    journal_title:Endoscopy

    pub_type: 杂志文章

    doi:10.1055/s-0028-1119602

    authors: Buscaglia JM,Dunbar KB,Okolo PI 3rd,Judah J,Akerman PA,Cantero D,Draganov PV

    更新日期:2009-03-01 00:00:00

  • Video Comment on Lobke Desomer et al.

    abstract:: ...

    journal_title:Endoscopy

    pub_type: 评论,杂志文章

    doi:10.1055/a-0744-2226

    authors:

    更新日期:2018-11-01 00:00:00

  • Biliary manometry in swine: a unique endoscopic model for teaching and research.

    abstract::Biliary manometry, the "gold standard" for the diagnosis of sphincter of Oddi dysfunction, is associated with technical and methodological problems. The lack of a suitable experimental model has hindered efforts to solve these problems. We report here on the first practical animal model for endoscopic biliary manometr...

    journal_title:Endoscopy

    pub_type: 杂志文章

    doi:10.1055/s-2007-1005636

    authors: Pasricha PJ,Tietjen TG,Kalloo AN

    更新日期:1995-01-01 00:00:00

  • Palliative laser therapy.

    abstract::Endoscopic laser treatment has been tried for hemostasis, relief of stenosis and reduction of tumor volume in advanced upper gastrointestinal cancer. This form of treatment was found to be effective for each purpose, but success was usually only temporary. Thus, it was considered that endoscopic laser therapy for prob...

    journal_title:Endoscopy

    pub_type: 杂志文章

    doi:10.1055/s-2007-1018301

    authors: Takemoto T,Okazaki Y,Otani T,Tanabe I,Fujimura H,Yoshida T,Fukumoto Y

    更新日期:1987-11-01 00:00:00

  • Cancer surveillance in ulcerative colitis: a survey of patients' knowledge.

    abstract:BACKGROUND AND STUDY AIMS:The present study aimed to investigate the level of knowledge concerning colorectal carcinoma and its screening and treatment in a group of patients with long-standing and extensive ulcerative colitis. PATIENTS AND METHODS:A postal questionnaire was sent to 61 patients with long-standing and ...

    journal_title:Endoscopy

    pub_type: 杂志文章

    doi:10.1055/s-2007-1005601

    authors: Robinson RJ,Hart AR,Mayberry JF

    更新日期:1996-11-01 00:00:00

  • Endoanal ultrasound-guided surgery for anal fistula.

    abstract:BACKGROUND AND STUDY AIMS:Outcomes following surgical treatment of patients with anal fistula are related to eradication of tracts and the internal opening. In this study, the results of surgery based on endoanal ultrasound (EAUS) findings were evaluated. PATIENTS AND METHODS:A total of 102 patients with primary crypt...

    journal_title:Endoscopy

    pub_type: 杂志文章

    doi:10.1055/s-2005-870155

    authors: Ratto C,Grillo E,Parello A,Costamagna G,Doglietto GB

    更新日期:2005-08-01 00:00:00

  • Higher adenoma detection rate with the endocuff: a randomized trial.

    abstract::Background and study aim Different techniques have been introduced to improve the endoscopist's view and enhance the detection of polyps. The endocuff is a polymer sleeve cap that is connected to the tip of the colonoscope in order to improve visualization of the mucosa during colonoscopy. The aim of the study was to ...

    journal_title:Endoscopy

    pub_type: 杂志文章,随机对照试验

    doi:10.1055/s-0043-117879

    authors: González-Fernández C,García-Rangel D,Aguilar-Olivos NE,Barreto-Zúñiga R,Romano-Munive AF,Grajales-Figueroa G,Zamora-Nava LE,Téllez-Avila FI

    更新日期:2017-11-01 00:00:00

  • Use of the urologic resectoscope in rectal pathology.

    abstract::We have resected five sessile polyps and treated rectal hemorrhage using the urologic resectoscope that operates in an aqueous solution. It is our belief that working in an aqueous environment can avoid some of the drawbacks of the standard technique in an air environment. We think that this is a useful technique in d...

    journal_title:Endoscopy

    pub_type: 杂志文章

    doi:10.1055/s-2007-1021527

    authors: Gaya J,Obrador A,Ozonas M,de Sala E

    更新日期:1983-07-01 00:00:00

  • Safe and effective digestive endoscopic resection in patients with cirrhosis: a single-center experience.

    abstract:BACKGROUND:Endoscopic resection has developed over the years. The main complications are perforation and bleeding. This study aimed to evaluate safety and effectiveness of digestive endoscopic resection in patients with cirrhosis. METHODS:This retrospective, open-label, single-center study included all consecutive pat...

    journal_title:Endoscopy

    pub_type: 杂志文章

    doi:10.1055/a-1089-9459

    authors: Miaglia C,Guillaud O,Rivory J,Lépilliez V,Chambon-Augoyard C,Hervieu V,Ponchon T,Dumortier J,Pioche M

    更新日期:2020-04-01 00:00:00

  • Development, standardization, and evaluation of NOTES cholecystectomy using a transsigmoid approach in the porcine model: an acute feasibility study.

    abstract:BACKGROUND:Transluminal cholecystectomy is feasible. However, the procedure is time consuming, difficult, and poorly standardized so far. In the present study we therefore aimed to further evaluate and optimize a transsigmoid approach for cholecystectomy with minimal transabdominal assistance in the porcine model. MET...

    journal_title:Endoscopy

    pub_type: 杂志文章

    doi:10.1055/s-2007-966904

    authors: Meining A,Wilhelm D,Burian M,Dundoulakis M,Schneider A,von Delius S,Feussner H

    更新日期:2007-10-01 00:00:00

  • Chromoendoscopy using indigo carmine dye spraying with magnifying observation is the most reliable method for differential diagnosis between non-neoplastic and neoplastic colorectal lesions: a prospective study.

    abstract:BACKGROUND AND AIMS:Differential diagnosis between non-neoplastic and neoplastic lesions is very important at colonoscopy, since removal or biopsy of non-neoplastic polyps wastes time and resources. We therefore conducted a prospective study to examine whether indigo carmine dye spraying with and without magnification ...

    journal_title:Endoscopy

    pub_type: 临床试验,杂志文章

    doi:10.1055/s-2004-826039

    authors: Fu KI,Sano Y,Kato S,Fujii T,Nagashima F,Yoshino T,Okuno T,Yoshida S,Fujimori T

    更新日期:2004-12-01 00:00:00

  • Dieulafoy's ulcer: combined endoscopic and laparoscopic treatment.

    abstract::Dieulafoy's disease is a rare, but dangerous cause of upper gastrointestinal hemorrhage. We report here the case of a patient in whom the failure of endoscopic therapy necessitated a surgical approach by combining endoscopy and laparoscopy. The intraoperative endoscopic examination located the site of the lesion preci...

    journal_title:Endoscopy

    pub_type: 杂志文章

    doi:10.1055/s-2007-1005488

    authors: Bouillot JL,Aubertin JM,Fornes P,Petite JP,Alexandre JH

    更新日期:1996-05-01 00:00:00

  • Contrast-harmonic endoscopic ultrasound for the diagnosis of pancreatic adenocarcinoma: a prospective multicenter trial.

    abstract:BACKGROUND AND STUDY AIMS:Histology is the gold standard for the diagnosis of pancreatic adenocarcinoma. However, the negative predictive value of endoscopic ultrasound-guided fine-needle aspiration (EUS-FNA) for the diagnosis remains low. The aims of this prospective multicenter study were: (1) to compare the performa...

    journal_title:Endoscopy

    pub_type: 杂志文章,多中心研究

    doi:10.1055/s-0034-1364969

    authors: Gincul R,Palazzo M,Pujol B,Tubach F,Palazzo L,Lefort C,Fumex F,Lombard A,Ribeiro D,Fabre M,Hervieu V,Labadie M,Ponchon T,Napoléon B

    更新日期:2014-05-01 00:00:00

  • Laser-induced shockwave lithotripsy of gallstones.

    abstract::With the aid of a Q-switched Nd:YAG laser with energy transmission via a flexible glass fiber, it proves possible under laboratory conditions, to destroy gallstones reliably and reproducibly. Lithotripsy is effected mechanically via a laser-induced local shockwave. ...

    journal_title:Endoscopy

    pub_type: 杂志文章

    doi:10.1055/s-2007-1018340

    authors: Ell C,Wondrazek F,Frank F,Hochberger J,Lux G,Demling L

    更新日期:1986-05-01 00:00:00

  • Prospective clinical study of endoscopic ultrasound-guided choledochoduodenostomy with direct metallic stent placement using a forward-viewing echoendoscope.

    abstract::A prospective clinical study was conducted to evaluate the safety, feasibility, and efficacy of endoscopic ultrasound (EUS)-guided choledochoduodenostomy (CDS) with direct metallic stent placement using a prototype forward-viewing echoendoscope. The indication for EUS - CDS in this study was lower biliary obstruction ...

    journal_title:Endoscopy

    pub_type: 临床试验,杂志文章

    doi:10.1055/s-0032-1326076

    authors: Hara K,Yamao K,Hijioka S,Mizuno N,Imaoka H,Tajika M,Kondo S,Tanaka T,Haba S,Takeshi O,Nagashio Y,Obayashi T,Shinagawa A,Bhatia V,Shimizu Y,Goto H,Niwa Y

    更新日期:2013-01-01 00:00:00

  • Evaluation of bipolar radiofrequency ablation for occluded self-expandable metal stents in the bile duct: in vivo and in vitro study.

    abstract:BACKGROUND AND AIMS:Endobiliary radiofrequency ablation (RFA) has been used to treat occluded self-expandable metal stents (SEMSs). The aim of this study was to determine the characteristics of bipolar RFA in occluded SEMSs using both in vivo and in vitro models. METHODS:For the in vivo study, uncovered SEMSs were dep...

    journal_title:Endoscopy

    pub_type: 杂志文章

    doi:10.1055/s-0034-1392252

    authors: Yoon WJ,Kim YT,Daglilar ES,Mino-Kenudson M,Brugge WR

    更新日期:2015-12-01 00:00:00

  • A randomized prospective trial comparing unsedated esophagoscopy via transnasal and transoral routes using a 4-mm video endoscope with conventional endoscopy with sedation.

    abstract:BACKGROUND AND STUDY AIMS:Unsedated upper endoscopy is an attractive alternative to conventional sedated endoscopy because it can reduce the cost, complications, and recovery time of the procedure. However, it has not gained widespread acceptance in the United States. A prototype 4-mm-diameter video esophagoscope is av...

    journal_title:Endoscopy

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1055/s-2005-861476

    authors: Thota PN,Zuccaro G Jr,Vargo JJ 2nd,Conwell DL,Dumot JA,Xu M

    更新日期:2005-06-01 00:00:00

  • Prospective evaluation of ERCP performance: results of a nationwide quality registry.

    abstract:BACKGROUND AND STUDY AIMS:Despite significant interest from health care authorities, patient organizations, and insurance companies, data on procedural outcome and quality of endoscopic retrograde cholangiopancreatography (ERCP) in general and academic practice are sparse. The aims of this study were to assess procedur...

    journal_title:Endoscopy

    pub_type: 临床试验,杂志文章

    doi:10.1055/s-0034-1391231

    authors: Ekkelenkamp VE,de Man RA,Ter Borg F,Borg PC,Bruno MJ,Groenen MJ,Hansen BE,van Tilburg AJ,Rauws EA,Koch AD

    更新日期:2015-06-01 00:00:00

  • New development of peroral cholangioscopy--evaluation of double-angle, oblique viewing cholangioscope.

    abstract::Seven years have passed since the first report on peroral cholangioscopy by Takekoshi and Takagi (1) in Japan. Recently, several types of peroral cholangioscope with a forceps channel have been made for this treatment. However, the success rate of insertion of these instruments into the common bile duct was less than ...

    journal_title:Endoscopy

    pub_type: 杂志文章

    doi:10.1055/s-2007-1018522

    authors: Fuji T,Ariyama S,Harima K,Aibe T,Amano H,Asagami F,Takemoto T

    更新日期:1984-01-01 00:00:00

  • Erosion and perforation of the biliary tree by plastic biliary endoprostheses.

    abstract::Biliary endoprostheses are increasingly used in the treatment of both benign and malignant pancreaticobiliary disorders. Common bile duct stones are a common clinical problem for which there now exist a range of treatment modalities. Official guidelines in the UK advocate the use of plastic biliary endoprostheses in t...

    journal_title:Endoscopy

    pub_type: 杂志文章

    doi:10.1055/s-0029-1244203

    authors: Sinha S,Wardle A,Kalidindi V,Banga N,Stoker DL

    更新日期:2010-09-01 00:00:00

  • ERCP-related adverse events: European Society of Gastrointestinal Endoscopy (ESGE) Guideline.

    abstract:PROPHYLAXIS:1:  ESGE recommends routine rectal administration of 100 mg of diclofenac or indomethacin immediately before endoscopic retrograde cholangiopancreatography (ERCP) in all patients without contraindications to nonsteroidal anti-inflammatory drug administration.Strong recommendation, moderate quality evidence....

    journal_title:Endoscopy

    pub_type: 杂志文章

    doi:10.1055/a-1075-4080

    authors: Dumonceau JM,Kapral C,Aabakken L,Papanikolaou IS,Tringali A,Vanbiervliet G,Beyna T,Dinis-Ribeiro M,Hritz I,Mariani A,Paspatis G,Radaelli F,Lakhtakia S,Veitch AM,van Hooft JE

    更新日期:2020-02-01 00:00:00

  • Endoscopic detachable snare ligation: a new treatment method for colonic diverticular hemorrhage.

    abstract:BACKGROUND AND STUDY AIMS:Colonic diverticular hemorrhage is the most common cause of lower intestinal bleeding. We tried to develop a convenient and reliable hemostatic method, endoscopic detachable snare ligation (EDSL), to treat diverticular hemorrhage and retrospectively explored its safety and efficacy. PATIENTS ...

    journal_title:Endoscopy

    pub_type: 杂志文章

    doi:10.1055/s-0034-1392204

    authors: Akutsu D,Narasaka T,Wakayama M,Terasaki M,Kaneko T,Matsui H,Suzuki H,Hyodo I,Mizokami Y

    更新日期:2015-11-01 00:00:00

  • Endoscopic anti-reflux valve for post-esophagectomy reflux: an animal study.

    abstract::Background and study aims: Gastric reflux into the remnant esophagus after subtotal or partial esophagectomy is associated with impairment in patient quality of life. We evaluated the feasibility, safety, and potential effectiveness of a novel procedure using a new endoscopic suturing device to create an anti-reflux v...

    journal_title:Endoscopy

    pub_type: 杂志文章

    doi:10.1055/s-0042-112572

    authors: Yanagimoto Y,Yamasaki M,Nagase H,Kanemura T,Higashi S,Miyazaki Y,Makino T,Takahashi T,Kurokawa Y,Miyata H,Takiguchi S,Mori M,Doki Y,Nakajima K

    更新日期:2016-12-01 00:00:00

  • Clinical use of new video-endoscopes (EVIS 100 and 200).

    abstract::The authors report on their clinical experience with two new videoendoscopes developed in cooperation with Olympus Co. One of them is an instantaneous image method videoendoscope (EVIS 100), the other produces sequential images (EVIS 200). EVIS 100 is as compact as a fiberscope; EVIS 200 has the special advantages of ...

    journal_title:Endoscopy

    pub_type: 杂志文章

    doi:10.1055/s-2007-1010467

    authors: Niwa H,Kawaguchi A,Miyahara T,Koyama H

    更新日期:1992-03-01 00:00:00

  • Future developments in total Barrett's eradication: the surgeon's view.

    abstract::Endoscopic therapies for the treatment of complicated Barret's esophagus should be embraced by the surgical community. While esophagectomy remains the standard of care for early esophageal neoplasia in many centers, endoscopic techniques are being increasingly utilizid. As refinements in both endoscopic and surgical a...

    journal_title:Endoscopy

    pub_type: 杂志文章,评审

    doi:10.1055/s-2008-1077783

    authors: Watson TJ,Peters JH

    更新日期:2008-12-01 00:00:00

  • The standard of laparoscopic intraoperative cholangiography: a quality control study.

    abstract:BACKGROUND AND STUDY AIMS:One reason why many surgeons do not attempt laparoscopic cholangiography is that it is considered to be technically difficult and to produce poor-quality images. PATIENTS AND METHODS:A retrospective comparison was made of twenty randomly selected intraoperative cholangiograms taken during lap...

    journal_title:Endoscopy

    pub_type: 杂志文章

    doi:10.1055/s-1999-13677

    authors: Arul GS,Rooney PS,Gregson R,Steele RJ

    更新日期:1999-03-01 00:00:00

  • Endoscopic closure of postoperative esophageal leaks with a novel over-the-scope clip system.

    abstract::Management of esophageal anastomotic leaks is associated with high morbidity and mortality and remains an interdisciplinary challenge. We describe the first two cases of endoscopic closure of postoperative leaks following gastrectomy and primary repair after spontaneous acute esophageal perforation, using the over-the...

    journal_title:Endoscopy

    pub_type: 杂志文章

    doi:10.1055/s-0030-1255634

    authors: Pohl J,Borgulya M,Lorenz D,Ell C

    更新日期:2010-09-01 00:00:00