Abstract：
:Cerebral palsy (CP) can occur in term infants with or without preceding newborn encephalopathy. We compared the type and severity of CP and associated disability in these two groups. Participants from a population-based case-control study of term newborn encephalopathy were followed up for 6 years and linked to the Western Australian Cerebral Palsy Register. The remaining term infants with CP for the same period were also identified from the Cerebral Palsy Register. 13% of neonatal survivors of term newborn encephalopathy had CP, a rate of 116 per 1000 term live births. Overall, 24% of term infants with CP followed newborn encephalopathy. CP following newborn encephalopathy was more likely to: affect males (72% vs 56%); be severe (47% vs 25%); and be of spastic quadriplegia or dyskinetic types. Cognitive impairment was more common (75% vs 43%) and severe (41% vs 16%), as was epilepsy (53% vs 29%) in survivors of encephalopathy. These children were also more likely to: be non-verbal (47% vs 22%); have a severe composite disability score (47% vs 26%); and die between time of diagnosis of CP and age 6 years (5-year cumulative mortality 19% vs 5%). Children born at term who develop CP following newborn encephalopathy have a poorer prognosis than those with CP who were not encephalopathic in the first week of life.
journal_name
Dev Med Child Neuroljournal_title
Developmental medicine and child neurologyauthors
Badawi N,Felix JF,Kurinczuk JJ,Dixon G,Watson L,Keogh JM,Valentine J,Stanley FJdoi
10.1017/s0012162205000575subject
Has Abstractpub_date
2005-05-01 00:00:00pages
293-8issue
5eissn
0012-1622issn
1469-8749journal_volume
47pub_type
杂志文章abstract：AIM:Language lateralization with functional transcranial Doppler sonography (fTCD) and lexical word generation has been shown to have high concordance with the Wada test and functional magnetic resonance imaging in adults. We evaluated a nonlexical paradigm to determine language dominance in children. METHOD:In 23 rig...
journal_title：Developmental medicine and child neurology
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更新日期：2017-07-01 00:00:00
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journal_title：Developmental medicine and child neurology
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pub_type： 杂志文章,评审
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journal_title：Developmental medicine and child neurology
pub_type： 历史文章,杂志文章
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