Abstract:
:We report a case of AL amyloidosis in a patient diagnosed with early gastric cancer after presenting with massive gastrointestinal hemorrhage and pseudo-obstruction of the small intestine. Primary systemic amyloidosis accounts for 7% of nonhematological malignancies, but very few cases of gastric carcinoma in patients with primary amyloidosis have been described. We performed distal gastrectomy with biopsy of the small intestine in the absence of a diagnosis of systemic amyloidosis associated with early gastric cancer; however, the patient suffered severe postoperative complications secondary to the amyloidosis. Although acute pseudo-obstruction is an uncommon clinical manifestation of AL amyloidosis, the coexistence of both gastrointestinal hemorrhage and pseudo-obstruction of the small intestine should alert the clinician to a diagnosis of gastrointestinal amyloidosis. We discuss the clinical manifestations of primary amyloidosis occurring in association with gastric cancer.
journal_name
Surg Todayjournal_title
Surgery todayauthors
Iwahashi N,Tame E,Nagasaka T,Furuta M,Nagashima H,Nimura Ydoi
10.1007/s00595-004-2805-6subject
Has Abstractpub_date
2004-01-01 00:00:00pages
871-4issue
10eissn
0941-1291issn
1436-2813journal_volume
34pub_type
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