Comparison of three different loading doses to establish epidural analgesia in labour.

Abstract:

:Women requesting epidural analgesia were randomized to receive one of three loading doses. Group 1 received a single dose of bupivacaine 9.375 mg (15 ml of 0.0625%) containing fentanyl 37.5 microg and adrenaline 37.5 microg group 2 received a single dose of bupivacaine 15 mg (15 ml of 0.1%) containing fentanyl 30 microg and adrenaline 30 microg and group 3 received a test dose of bupivacaine 10 mg (4 ml of 0.25% - test) followed 5 min later by bupivacaine 20 mg (8 ml of 0.25% - loading). All groups received an infusion of bupivacaine 0.0625% with fentanyl 0.00025% and adrenaline 0.00025% at 10-12 ml/h started 15 min after the loading dose. Speed of onset of analgesia was the same in all three groups, with the majority of women achieving satisfactory analgesia by 20 min. Motor block was significantly increased in group 3 at 30 min, but by 1 h there was no difference in motor block between the groups.

journal_name

Int J Obstet Anesth

authors

Scrutton MJ,Porter JS,O'Sullivan G

doi

10.1016/s0959-289x(98)80005-8

subject

Has Abstract

pub_date

1998-07-01 00:00:00

pages

165-9

issue

3

eissn

0959-289X

issn

1532-3374

pii

S0959-289X(98)80005-8

journal_volume

7

pub_type

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