Functional and cognitive consequences of silent stroke discovered using brain magnetic resonance imaging in an elderly population.

Abstract:

OBJECTIVES:To evaluate the prevalence of silent stroke and its associated consequences on physical, cognitive, and emotional functioning in an elderly population. DESIGN:Population-based cross-sectional survey. SETTING:The Memory and Morbidity in Augsburg Elderly project in the Augsburg region of southern Germany. PARTICIPANTS:Two hundred sixty-seven community-dwelling persons aged 65 to 83. MEASUREMENTS:The presence of silent stroke was determined using magnetic resonance imaging brain scan and a single question asking for physician-diagnosed stroke in each participant. The health effect of silent stroke was assessed using rating scales for self-perceived health status (36-item short-form health survey), activities of daily living (ADLs) and instrumental ADLs, cognitive function, and depression (Center for Epidemiologic Studies Depression scale). RESULTS:Just fewer than 13% (12.7%) of participants were affected by silent stroke. Silent stroke was associated with a history of hypertension, heart surgery, and elevated C-reactive protein. Individuals with silent stroke showed impairments on the Mini-Mental State Examination test and in the cognitive domains of memory, procedural speed, and motor performance. CONCLUSION:The presence of silent stroke has a considerable effect on cognitive performance in those affected. Determining the presence of silent stroke using brain imaging may contribute to identifying individuals at risk for developing gradual neurological deficits.

journal_name

J Am Geriatr Soc

authors

Schmidt WP,Roesler A,Kretzschmar K,Ladwig KH,Junker R,Berger K

doi

10.1111/j.1532-5415.2004.52300.x

subject

Has Abstract

pub_date

2004-07-01 00:00:00

pages

1045-50

issue

7

eissn

0002-8614

issn

1532-5415

pii

JGS52300

journal_volume

52

pub_type

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