当前位置： SCI文献检索 > OBESITY SURGERY期刊下所有文献 > Outcome of pregnancies after biliopancreatic diversion.

Outcome of pregnancies after biliopancreatic diversion.

Abstract：

BACKGROUND:Severe obesity has deleterious effects on fertility and pregnancy outcomes. Although surgery is the best long-term treatment for severe obesity, there is a risk of gestational undernutrition in operated mothers because bariatric surgery reduces nutrient availability. This is a follow-up report of our initial findings regarding pregnancy and neonatal outcomes in biliopancreatic diversion (BPD) patients, with addition of a new cohort of children born to mothers after BPD. METHODS:All women (n = 916) who had successfully undergone BPD in our hospital were mailed a questionnaire containing multiple-choice and essay questions concerning gynecologic and obstetric history, and pregnancy and neonatal outcomes in both preoperative and postoperative pregnancies. Patients operated between 1984 and 1995 (n = 568) were mailed an additional questionnaire regarding children's weight and height progress, and school performance. Perinatal records from our patients' obstetric clinics were also reviewed. RESULTS:The questionnaire was completed by 783 women (85.5%). 251 postoperative pregnancies in 132 women resulted in 166 infants by 109 mothers. 47.0% of patients who were unable to become pregnant preoperatively were successful postoperatively. 90 out of 109 women (82.6%) reported an appropriate weight gain (9.1 +/- 5.9 kg) during postoperative pregnancies. The incidence of fetal macrosomia decreased from 34.8 to 7.7%, with a concomitant increase in normal-weight babies from 62.1 to 82.7%. The elevated miscarriage rate (26.0%) in these obese women persisted after surgery. CONCLUSION:Major weight loss following BPD improves the reproductive function of severely obese women. BPD provides major beneficial effects for both mother and child, including normalization of gestational weight changes, reduction of fetal macrosomia, and normalization of the infant's birth-weight. Our results speak in favor of delaying pregnancy in obese women until after the substantial surgical weight loss has occurred.

journal_name

Obes Surg

journal_title

Obesity surgery

authors

Marceau P,Kaufman D,Biron S,Hould FS,Lebel S,Marceau S,Kral JG

doi

10.1381/096089204322917819

subject

Has Abstract

pub_date

2004-03-01 00:00:00

pages

318-24

issue

eissn

0960-8923

issn

1708-0428

journal_volume

pub_type

杂志文章

在线工具

Outcome of pregnancies after biliopancreatic diversion.