Vitreous haemorrhage in elderly patients: management and prevention.

Abstract:

:Vitreous haemorrhage can be caused by a disruption of normal retinal vessels, bleeding from diseased retinal vessels, bleeding from abnormal new vessels or extension of haemorrhage through the retina from other sources. In the elderly, vitreous haemorrhage usually occurs spontaneously and only occurs occasionally as a result of trauma. Appropriate management of vitreous haemorrhage is dependent on the most likely cause in a particular patient. As always, an accurate medical history with a careful clinical examination, static and dynamic ultrasonography performed by an experienced examiner, results of other laboratory tests and an understanding of the common causes of vitreous haemorrhage in each age group is essential to come to a 'best guess' diagnosis as to the cause of the vitreous haemorrhage and thus guide the physician toward the appropriate management. Immediate surgical removal of blood if indicated, as well as improving the vision gives the added benefit of allowing a full examination of the underlying retina. For those in whom surgical removal of blood is not recommended, a careful and frequent follow-up with serial B-scan ultrasound allows the 'best guess' diagnosis to be confirmed at each visit, until such time as the vitreous haemorrhage resolves sufficiently to allow a full and proper examination of the retina. Where there is a confirmed retinal tear, retinal detachment or other fundal pathology these are treated appropriately with laser or surgery (vitrectomy). Preventative measures are dependent on the underlying cause of vitreous haemorrhage. Some of the underlying causes such as posterior vitreous detachment cannot be prevented. In others, such as retinal vein occlusion, measures may need to be taken so as to reduce the risk of a similar event in the same or fellow eye and to reduce the risk of potentially life-threatening associated systemic conditions such as a stroke or myocardial infarction.

journal_name

Drugs Aging

journal_title

Drugs & aging

authors

Manuchehri K,Kirkby G

doi

10.2165/00002512-200320090-00003

subject

Has Abstract

pub_date

2003-01-01 00:00:00

pages

655-61

issue

9

eissn

1170-229X

issn

1179-1969

pii

2093

journal_volume

20

pub_type

杂志文章,评审
  • The association of inappropriate drug use with hospitalisation and mortality: a population-based study of the very old.

    abstract:BACKGROUND AND OBJECTIVE:Inappropriate prescribing is an important and possibly preventable risk factor for adverse drug reactions (ADRs) in the elderly, and hospital-based studies have shown that a large proportion of admissions is a result of ADRs. However, little is known about how inappropriate drug use (IDU) affec...

    journal_title:Drugs & aging

    pub_type: 杂志文章

    doi:10.2165/00002512-200522010-00005

    authors: Klarin I,Wimo A,Fastbom J

    更新日期:2005-01-01 00:00:00

  • Current management strategies for hepatitis B in the elderly.

    abstract::Despite the availability of an efficient vaccine, chronic hepatitis B virus (HBV) infection remains a major public health problem worldwide. The World Health Organization estimates that there are still 350 million chronic carriers of the virus who are at risk of developing chronic hepatitis, liver cirrhosis and hepato...

    journal_title:Drugs & aging

    pub_type: 杂志文章,评审

    doi:10.2165/00002512-200118100-00002

    authors: Merle P,Trépo C,Zoulim F

    更新日期:2001-01-01 00:00:00

  • Opioids for the treatment of chronic non-cancer pain in older people.

    abstract::Chronic pain occurs in 45-85% of the geriatric population and the need to treat chronic pain is growing substantially. Unfortunately, treatment for chronic pain is not always correctly targeted, which leads to a reduced quality of life, with decreased socialization, depression, sleep disturbances, cognitive impairment...

    journal_title:Drugs & aging

    pub_type: 杂志文章,评审

    doi:10.2165/11534670-000000000-00000

    authors: Gianni W,Ceci M,Bustacchini S,Corsonello A,Abbatecola AM,Brancati AM,Assisi A,Scuteri A,Cipriani L,Lattanzio F

    更新日期:2009-12-01 00:00:00

  • Statin Use is Not Associated with Future Long-Term Care Admission: Extended Follow-Up of Two Randomised Controlled Trials.

    abstract:BACKGROUND:Statins have been associated with later life, long-term care admission in observational studies. However, by preventing vascular events, statins may also prevent or delay admission. We wished to determine statin and long-term care admission associations in a randomised controlled trial context, and describe ...

    journal_title:Drugs & aging

    pub_type: 杂志文章,随机对照试验

    doi:10.1007/s40266-018-0560-4

    authors: Burton JK,Papworth R,Haig C,McCowan C,Ford I,Stott DJ,Quinn TJ

    更新日期:2018-07-01 00:00:00

  • Inhaled corticosteroids in the long-term management of patients with chronic obstructive pulmonary disease.

    abstract::Chronic obstructive pulmonary disease (COPD) is a major problem in the elderly population, with approximately 10% of the population affected. Since COPD is an inflammatory disorder of the pulmonary system, corticosteroids might be expected to improve clinical outcomes of the disease. Data from large, well designed ran...

    journal_title:Drugs & aging

    pub_type: 杂志文章,评审

    doi:10.2165/00002512-200320120-00001

    authors: Sin DD,Man SF

    更新日期:2003-01-01 00:00:00

  • Recent Progress in the Pharmacotherapy of Alzheimer's Disease.

    abstract::Alzheimer's disease is the most common major neurocognitive disorder with substantial social and economic impacts. This article is an update on current pharmacotherapy, advancements in biomarker use, and drugs in the pipeline for this disease. To date, no new drug has qualified to be added to the current therapeutic a...

    journal_title:Drugs & aging

    pub_type: 杂志文章,评审

    doi:10.1007/s40266-017-0499-x

    authors: Khoury R,Patel K,Gold J,Hinds S,Grossberg GT

    更新日期:2017-11-01 00:00:00

  • Polymyalgia rheumatica and giant cell arteritis in older patients: diagnosis and pharmacological management.

    abstract::Giant cell arteritis (GCA) is an inflammatory vasculopathy that involves large- and medium-sized arteries and can cause vision loss, stroke and aneurysms. GCA occurs in people aged >50 years and is more common in women. A higher incidence of the disease is observed in populations from Northern European countries. Poly...

    journal_title:Drugs & aging

    pub_type: 杂志文章,评审

    doi:10.2165/11592500-000000000-00000

    authors: Schmidt J,Warrington KJ

    更新日期:2011-08-01 00:00:00

  • Information for physicians and pharmacists about drugs that might cause dry mouth: a study of monographs and published literature.

    abstract:BACKGROUND:Over three-quarters of the older population take medications that can potentially cause dry mouth. Physicians or pharmacists rarely inform patients about this adverse effect and its potentially severe damage to the teeth, mouth and general health. OBJECTIVES:The objectives of this study were to (1) identify...

    journal_title:Drugs & aging

    pub_type: 杂志文章

    doi:10.1007/s40266-013-0141-5

    authors: Nguyen CT,MacEntee MI,Mintzes B,Perry TL

    更新日期:2014-01-01 00:00:00

  • Use of Medicines that May Exacerbate Heart Failure in Older Adults: Therapeutic Complexity of Multimorbidity.

    abstract:BACKGROUND:Multimorbidity is common in older patients with heart failure (HF), complicating therapeutic management and increasing the risk of harm. OBJECTIVE:This study sought to examine the prevalence of medicines for the treatment of comorbid conditions potentially associated with harm in older people, before and af...

    journal_title:Drugs & aging

    pub_type: 杂志文章

    doi:10.1007/s40266-019-00645-0

    authors: Caughey GE,Shakib S,Barratt JD,Roughead EE

    更新日期:2019-05-01 00:00:00

  • Age-related changes in signal transduction. Implications for neuronal transmission and potential for drug intervention.

    abstract::Problems associated with aging will become one of the leading health dilemmas of the next century. Age-associated diseases, including those affecting the neuronal system, are increasing in frequency. Age-related deficiencies in the brain result in impaired motor functions, sleep, behaviour and cognitive functions. Goo...

    journal_title:Drugs & aging

    pub_type: 杂志文章,评审

    doi:10.2165/00002512-199405050-00006

    authors: Fülöp T Jr,Seres I

    更新日期:1994-11-01 00:00:00

  • Once-daily trospium chloride 60 mg extended release in subjects with overactive bladder syndrome who use multiple concomitant medications: Post hoc analysis of pooled data from two randomized, placebo-controlled trials.

    abstract:BACKGROUND:Overactive bladder syndrome (OAB) is associated with various co-morbidities; treatment of these frequently results in multiple medication use (MMU) and the potential for drug-drug interactions, which may lead to adverse events and altered efficacy. With the aging population, the prevalence of MMU is likely t...

    journal_title:Drugs & aging

    pub_type: 杂志文章,多中心研究,随机对照试验

    doi:10.2165/11586740-000000000-00000

    authors: Sand PK,Rovner ES,Watanabe JH,Oefelein MG

    更新日期:2011-02-01 00:00:00

  • Potentially Inappropriate Antihypertensive Prescriptions to Elderly Patients: Results of a Prospective, Observational Study.

    abstract:INTRODUCTION:Previous studies of antihypertensive treatment of older patients have focused on blood pressure control, cardiovascular risk or adherence, whereas data on inappropriate antihypertensive prescriptions to older patients are scarce. OBJECTIVES:The aim of the study was to assess inappropriate antihypertensive...

    journal_title:Drugs & aging

    pub_type: 杂志文章,多中心研究

    doi:10.1007/s40266-017-0452-z

    authors: Márquez PHP,Torres OH,San-José A,Vidal X,Agustí A,Formiga F,López-Soto A,Ramírez-Duque N,Fernández-Moyano A,Garcia-Moreno J,Arroyo JA,Ruiz D,Potentially Inappropriate Prescription in Older Patients in Spain (PIPOPS) Investigators

    更新日期:2017-06-01 00:00:00

  • Suitable Use of Injectable Agents to Overcome Hypoglycemia Risk, Barriers, and Clinical Inertia in Community-Dwelling Older Adults with Type 2 Diabetes Mellitus.

    abstract::The management of type 2 diabetes mellitus in older adults requires a comprehensive understanding of the relationship between the disease (medical) and the functional, psychological/cognitive, and social geriatric domains, to individualize both glycemic targets and therapeutic approaches. Prevention of hypoglycemia is...

    journal_title:Drugs & aging

    pub_type: 杂志文章,评审

    doi:10.1007/s40266-019-00706-4

    authors: Valencia WM,Florez HJ,Palacio AM

    更新日期:2019-12-01 00:00:00

  • Metronomic chemotherapy for metastatic prostate cancer: a 'young' concept for old patients?

    abstract::Prostate cancer is a common disease in the elderly, and the number of older prostate cancer patients will probably increase with both the aging of the population and the increased rate of screening. In elderly patients with several co-morbidities, cancer management can be complex, and the risk of administering toxic t...

    journal_title:Drugs & aging

    pub_type: 杂志文章,评审

    doi:10.2165/11537480-000000000-00000

    authors: Fontana A,Falcone A,Derosa L,Di Desidero T,Danesi R,Bocci G

    更新日期:2010-09-01 00:00:00

  • International Group for Reducing Inappropriate Medication Use & Polypharmacy (IGRIMUP): Position Statement and 10 Recommendations for Action.

    abstract::Globally, the number of drug prescriptions is increasing causing more adverse drug events, which is now a significant cause of mortality, morbidity, and disability that has reached epidemic proportions. The risk of adverse drug events is correlated to very old age, multiple co-morbidities, dementia, frailty, and limit...

    journal_title:Drugs & aging

    pub_type: 杂志文章

    doi:10.1007/s40266-018-0554-2

    authors: Mangin D,Bahat G,Golomb BA,Mallery LH,Moorhouse P,Onder G,Petrovic M,Garfinkel D

    更新日期:2018-07-01 00:00:00

  • Multiple sclerosis in the elderly patient.

    abstract::Multiple sclerosis (MS) is an acquired inflammatory demyelinating disease of the CNS that is typically diagnosed in the second or third decade of life. It is generally believed that over the last few decades the life expectancy of patients with adult onset MS (AOMS) has approached that of the general population as a r...

    journal_title:Drugs & aging

    pub_type: 杂志文章,评审

    doi:10.2165/11532120-000000000-00000

    authors: Awad A,Stüve O

    更新日期:2010-04-01 00:00:00

  • Advances in the pharmacological treatment of gastro-oesophageal cancer.

    abstract::Despite a sharp decline in the incidence of gastric cancer during the second half of the 20th century, this malignancy remains the second leading cause of cancer mortality in the world. The incidence and mortality rate of gastric cancer increase with age; at present, the median ages at diagnosis are 67 years for men a...

    journal_title:Drugs & aging

    pub_type: 杂志文章,评审

    doi:10.2165/11315740-000000000-00000

    authors: Wagner AD,Wedding U

    更新日期:2009-01-01 00:00:00

  • Treating asthma in the older patient: is there a place for leukotriene modifiers?

    abstract::Asthma is a common airway disease found in people of all ages, although most studies of asthma therapies are focused on adolescent and young adults. Little information exists on the use of asthma therapeutics in the older patient (>65 years of age). The newest therapeutic class to be released in the US for the treatme...

    journal_title:Drugs & aging

    pub_type: 杂志文章,评审

    doi:10.2165/00002512-200623060-00002

    authors: Grayson MH,Korenblat PE

    更新日期:2006-01-01 00:00:00

  • Pharmacoeconomics of influenza vaccination in the elderly: reviewing the available evidence.

    abstract::Most western countries have influenza vaccination programmes for citizens aged > or = 65 years. This paper reviews the available evidence on whether elderly influenza vaccination is worthwhile from a pharmacoeconomic point of view. A search on Medline and EMBASE resulted in a primary selection of approximately 100 stu...

    journal_title:Drugs & aging

    pub_type: 杂志文章,评审

    doi:10.2165/00002512-200017030-00005

    authors: Postma MJ,Baltussen RM,Heijnen ML,de Berg LT,Jager JC

    更新日期:2000-09-01 00:00:00

  • Characteristics of New-Onset and Chronic Sleep Medication Users Among Older Adults: A Retrospective Study of a US Medigap Plan Population using Propensity Score Matching.

    abstract:BACKGROUND:Prescription sleep medications are often utilized to manage sleep problems among older adults even though these drugs are associated with multiple risks. OBJECTIVE:The aim was to determine the prevalence and characteristics of new-onset compared to chronic sleep medication users and to examine factors assoc...

    journal_title:Drugs & aging

    pub_type: 杂志文章

    doi:10.1007/s40266-018-0543-5

    authors: Musich S,Wang SS,Slindee LB,Saphire L,Wicker E

    更新日期:2018-05-01 00:00:00

  • First-line treatment strategies for elderly patients with metastatic colorectal cancer.

    abstract::Colorectal cancer ranks third in incidence in both men and women after lung, breast and prostate cancer. The prevalence of colorectal cancer increases significantly with age, with 40% of patients in Europe being >75 years of age at the time of initial diagnosis. Furthermore, the number of elderly patients with colorec...

    journal_title:Drugs & aging

    pub_type: 杂志文章,评审

    doi:10.2165/00002512-200724030-00004

    authors: Meulenbeld HJ,Creemers GJ

    更新日期:2007-01-01 00:00:00

  • Getting better, getting well: understanding and managing partial and non-response to pharmacological treatment of non-psychotic major depression in old age.

    abstract::In general, the pharmacological treatment of non-psychotic major depressive disorder in old age is only partially successful, with only approximately 50% of older depressed adults improving with initial antidepressant monotherapy. Many factors may predict a more difficult-to-treat depression, including coexisting anxi...

    journal_title:Drugs & aging

    pub_type: 杂志文章,评审

    doi:10.2165/00002512-200724100-00002

    authors: Driscoll HC,Karp JF,Dew MA,Reynolds CF 3rd

    更新日期:2007-01-01 00:00:00

  • Clinical relevance of hyperhomocysteinaemia in atherothrombotic disease.

    abstract::High fasting plasma homocysteine levels (> 12 to 15 mumol/L) are commonly encountered in clinical practice and are associated with increased risk of atherothrombotic disease. Treatment with folic acid (1 to 5 mg/day) is inexpensive and effective in normalising plasma homocysteine levels. High plasma homocysteine level...

    journal_title:Drugs & aging

    pub_type: 杂志文章,评审

    doi:10.2165/00002512-200016040-00001

    authors: Stehouwer DA

    更新日期:2000-04-01 00:00:00

  • Cutaneous Drug Reactions in the Elderly.

    abstract::Cutaneous adverse drug reactions comprise a significant proportion of all adverse drug reactions. They may mimic other dermatologic or systemic illnesses and may cause significant morbidity or mortality. Seven morphologic groups encompass the most commonly encountered cutaneous drug reaction syndromes: exanthematous (...

    journal_title:Drugs & aging

    pub_type: 杂志文章,评审

    doi:10.1007/s40266-017-0483-5

    authors: Young JWS,Shear NH

    更新日期:2017-09-01 00:00:00

  • The economic burden of glaucoma and ocular hypertension: implications for patient management: a review.

    abstract::This paper reviews the burden and economic consequences of glaucoma upon healthcare systems and patients, especially elderly patients. An extensive review of the literature was conducted, primarily using MEDLINE, but also by examining selected article reference lists, relevant websites and the proceedings of specialis...

    journal_title:Drugs & aging

    pub_type: 杂志文章,评审

    doi:10.2165/00002512-200522040-00004

    authors: Rouland JF,Berdeaux G,Lafuma A

    更新日期:2005-01-01 00:00:00

  • Improving elder care by integrating geriatric expertise into medicare: a proposal.

    abstract::The Medicare programme already funds a large proportion of the medical care for older Americans. However, geriatricians are an underutilized resource for improving the quality of care delivered with Medicare funding, particularly to the most complex patients. Recent legislative changes will increase the involvement of...

    journal_title:Drugs & aging

    pub_type: 杂志文章,评审

    doi:10.2165/00002512-200522050-00002

    authors: Nusbaum NJ

    更新日期:2005-01-01 00:00:00

  • Beta-blockers for congestive heart failure: what is the current consensus?

    abstract::Despite the availability of angiotensin converting enzyme (ACE) inhibitors for patients with congestive heart failure (CHF), mortality and morbidity remains unacceptably high. CHF is thought to progress as a result of activation of endogenous neurohormonal systems which are activated by the initial myocardial injury. ...

    journal_title:Drugs & aging

    pub_type: 杂志文章,评审

    doi:10.2165/00002512-200016010-00001

    authors: Tsuyuki RT,McAlister FA,Teo KK

    更新日期:2000-01-01 00:00:00

  • Drug therapy of prostatic cancer.

    abstract::While hormonal therapy has been the usual and appropriate treatment of advanced or metastatic prostatic cancer for the past 50 years, the recent development of new therapeutic agents as medical alternatives to orchidectomy has drastically altered the options and perspectives in the treatment of this disease. Estrogens...

    journal_title:Drugs & aging

    pub_type: 杂志文章,评审

    doi:10.2165/00002512-199101050-00003

    authors: Huben RP,Perrapato SD

    更新日期:1991-09-01 00:00:00

  • Drug-Drug Interactions and Prescription Appropriateness in Patients with COVID-19: A Retrospective Analysis from a Reference Hospital in Northern Italy.

    abstract:BACKGROUND:Patients hospitalised with severe acute respiratory syndrome coronavirus 2 [SARS-CoV-2; coronavirus 2019 disease (COVID-19)] infection are frequently older with co-morbidities and receiving polypharmacy, all of which are known risk factors for drug-drug interactions (DDIs). The pharmacological burden may be ...

    journal_title:Drugs & aging

    pub_type: 杂志文章

    doi:10.1007/s40266-020-00812-8

    authors: Cattaneo D,Pasina L,Maggioni AP,Giacomelli A,Oreni L,Covizzi A,Bradanini L,Schiuma M,Antinori S,Ridolfo A,Gervasoni C

    更新日期:2020-12-01 00:00:00

  • Nitrates in the elderly. Pharmacological considerations.

    abstract::Although a significant proportion of patients receiving nitrates are elderly, surprisingly little published work is available describing the pharmacokinetics and pharmacodynamics of these agents in elderly patients. The lack of pharmacokinetic data is related to the difficulty in assaying nitrates and there are at pre...

    journal_title:Drugs & aging

    pub_type: 杂志文章,评审

    doi:10.2165/00002512-199202010-00003

    authors: Kelly JG,O'Malley K

    更新日期:1992-01-01 00:00:00