Abstract:
BACKGROUND AND PURPOSE:Oxalobacter formigenes is an anaerobic commensal colonic bacterium capable of degrading oxalate through the enzyme oxalyl-CoA decarboxylase. It has been theorized that individuals who lack this bacterium have higher intestinal oxalate absorption, leading to a higher urinary oxalate concentration and an increased risk of calcium oxalate urolithiasis. We performed a prospective, controlled study to evaluate O. formigenes colonization in calcium oxalate stone formers and to correlate colonization with urinary oxalate and other standard urinary stone risk factors. PATIENTS AND METHODS:Thirty-five first-time calcium oxalate stone formers were compared with 10 control subjects having no history of urolithiasis and a normal renal ultrasound scan. All subjects underwent standard metabolic testing by submitting serum and 24-hour urine specimens. In addition, all subjects submitted stool samples for culture and detection of O. formigenes by Xentr(ix) O. formigenes Monitor. RESULTS:Intestinal Oxalobacter was detected in only 26% of the stone formers compared with 60% of the controls (p < 0.05). Overall, the average urinary oxalate excretion by the two groups was similar (38.6 mg/day v 40.8 mg/day). Among stone formers, however, there were statistically higher urinary oxalate concentrations in O. formigenes-negative patients compared with those testing positive (41.7 mg/day v 29.4 mg/day) (p = 0.03). Furthermore, all 10 stone formers with hyperoxaluria (>44 mg/day) tested negative for O. formigenes (p < 0.05). CONCLUSIONS:Calcium oxalate stone formers have a low rate of colonization with O. formigenes. Among stone formers, absence of intestinal Oxalobacter correlates with higher urinary oxalate concentration and an increased risk of hyperoxaluria. Introduction of the Oxalobacter bacterium or an analog of its enzyme oxalyl-CoA decarboxylase into the intestinal tract may be a treatment for calcium oxalate stone disease.
journal_name
J Endouroljournal_title
Journal of endourologyauthors
Troxel SA,Sidhu H,Kaul P,Low RKdoi
10.1089/089277903321618743subject
Has Abstractpub_date
2003-04-01 00:00:00pages
173-6issue
3eissn
0892-7790issn
1557-900Xjournal_volume
17pub_type
杂志文章abstract::Recently, the use of botulinum toxin A has been extended to patients with non-neurogenic urologic disorders such as refractory idiopathic overactive bladder. We describe a modification of our original injection technique that allows one to deliver botulinum toxin into the bladder quickly and efficiently in an office s...
journal_title:Journal of endourology
pub_type: 杂志文章
doi:10.1089/end.2005.19.880
更新日期:2005-09-01 00:00:00
abstract:PURPOSE:To present our preliminary experience with laparoscopic renal cryoablation in patients with small renal tumors and severe comorbidities. PATIENTS AND METHODS:Eight patients with a mean age of 75.6 years (range 68-82 years) who had small (mean 2.6+/-0.7-cm; range 1.4-3.8-cm) peripheral renal cortical lesions an...
journal_title:Journal of endourology
pub_type: 杂志文章
doi:10.1089/089277903767923227
更新日期:2003-08-01 00:00:00
abstract::A 55-year-old man had a solid tumor in the right part of a horseshoe kidney. He had previously undergone open cholecystectomy and appendectomy with panperitonitis. Retroperitoneoscopic nephrectomy was performed, with rapid recovery and good short-term results. This appears to be the first case of endoscopic surgery on...
journal_title:Journal of endourology
pub_type: 杂志文章
doi:10.1089/089277903772036253
更新日期:2003-12-01 00:00:00
abstract:BACKGROUND AND PURPOSE:Nucleation, growth, and aggregation are considered to be the principal crystallization mechanisms in stone development. It is important to understand their relative significance so that appropriate experimental models can be used, and to identify the best therapeutic targets. The aim of this stud...
journal_title:Journal of endourology
pub_type: 杂志文章
doi:10.1089/end.1999.13.605
更新日期:1999-11-01 00:00:00
abstract:OBJECTIVE:To assess the association between the R.E.N.A.L. Nephrometry score, the amount of non-neoplastic parenchymal volume (NNPV) removed, and the renal function decline in patients undergoing robotic partial nephrectomy (RPN). PATIENTS AND METHODS:The Multi-institutional Mount Sinai Kidney Cancer Database was used...
journal_title:Journal of endourology
pub_type: 杂志文章
doi:10.1089/end.2016.0337
更新日期:2016-10-01 00:00:00
abstract:BACKGROUND AND PURPOSE:Holmium:yttrium-aluminum-garnet (Ho:YAG) laser lithotripsy is the standard lithotrite in ureteroscopy. We investigated the influence of pulse frequency, energy and length on the fragmentation efficiency of Ho:YAG laser lithotripsy in non-floating artificial stones in vitro. MATERIALS AND METHODS...
journal_title:Journal of endourology
pub_type: 杂志文章
doi:10.1089/end.2010.0115
更新日期:2010-07-01 00:00:00
abstract:PURPOSE:To provide a comprehensive review of the classification of surgical errors as well as general measures to detect and prevent their occurrence. MATERIALS AND METHODS:Search in PubMed, Medline, and Cochrane library with combination of the key words: Endoscopy or surgical procedures, minimally invasive, and medic...
journal_title:Journal of endourology
pub_type: 杂志文章,meta分析
doi:10.1089/end.2011.0068
更新日期:2011-11-01 00:00:00
abstract:OBJECTIVE:To evaluate in vitro and in vivo effects of Moses technology in Holmium laser and to compare it with the Regular mode in terms of lithotripsy efficiency and laser-tissue interactions. METHODS:The Lumenis® Pulse™ P120H holmium laser system together with Moses D/F/L fibers were used to compare the Regular mode...
journal_title:Journal of endourology
pub_type: 杂志文章
doi:10.1089/end.2017.0050
更新日期:2017-06-01 00:00:00
abstract::Ureteral obstruction secondary to extrinsic compression is uncommon. Extrinsic compression results from both benign and malignant conditions of the retroperitoneum. In certain patients, laparoscopic ureterolysis is a minimally invasive alternative to the open approach. To date, the largest numbers of patients have und...
journal_title:Journal of endourology
pub_type: 杂志文章,评审
doi:10.1089/end.2005.19.710
更新日期:2005-07-01 00:00:00
abstract::The article entitled, "Mn-porphyrins as novel molecular MRI contrast agents" by Mouraviev et al., published online ahead of print on November 3, 2011 (DOI: 10.1089/end.2011.0133), in its unedited, uncorrected format, is being officially withdrawn from Journal of Endourology. This early version of the manuscript was no...
journal_title:Journal of endourology
pub_type: 撤回出版物
doi:10.1089/end.2011.0133.ret
更新日期:2012-10-01 00:00:00
abstract:BACKGROUND AND PURPOSE:Vascular control is an important step in laparoscopic nephrectomy. The various options are titanium clips, Hem-o-lok clips (Weck Closure Systems, Research Triangle Park, NC), T-knot, and stapling devices. We report our experience with the use of Hem-o-lok clips. PATIENTS AND METHODS:From January...
journal_title:Journal of endourology
pub_type: 杂志文章
doi:10.1089/end.2006.20.202
更新日期:2006-03-01 00:00:00
abstract:PURPOSE:Microdialysis is an innovative technique used to monitor the chemistry of the interstitial fluid in living tissue. We documented changes in concentration of interstitial fluid metabolites before, during, and after induced renal ischemia. MATERIALS AND METHODS:Under general anesthesia, a microdialysis probe was...
journal_title:Journal of endourology
pub_type: 杂志文章
doi:10.1089/end.2007.0256
更新日期:2008-03-01 00:00:00
abstract:BACKGROUND AND PURPOSE:Port-site metastasis (PSM) is a rare complication of laparoscopic intervention in urologic malignancies. Of the greater than 50 reported cases of PSM in the urologic oncology literature, only 9 have occurred after surgery for renal-cell carcinoma (RCC). We report a 10th instance of RCC metastasis...
journal_title:Journal of endourology
pub_type: 杂志文章
doi:10.1089/end.2012.0533
更新日期:2013-06-01 00:00:00
abstract:BACKGROUND AND PURPOSE:The optimal treatment option for ureteral calculi is a controversial issue. In this study, we present our experience of 60 patients, divided into three groups, who were treated using open surgery, laparoscopic surgery, or transureteral lithotripsy (TUL). PATIENTS AND METHODS:We enrolled 60 patie...
journal_title:Journal of endourology
pub_type: 临床试验,杂志文章
doi:10.1089/end.2010.0344
更新日期:2011-01-01 00:00:00
abstract:OBJECTIVE:Intraoperative mannitol is routinely administered for renoprotection in partial nephrectomy (PN). However, there is a paucity of evidence supporting mannitol's renoprotective effect. We performed a retrospective study of mannitol's efficacy in PN. MATERIALS AND METHODS:Using an institutional database, patien...
journal_title:Journal of endourology
pub_type: 杂志文章
doi:10.1089/end.2017.0415
更新日期:2018-04-01 00:00:00
abstract::Severe urethral stricture disease as an isolated entity can be a management dilemma. In the patient described here, this problem was associated with prior external-beam radiation and cryosurgical ablation of the prostate, and a functional artificial urethral sphincter (AUS) had been placed. An attempt to relieve parti...
journal_title:Journal of endourology
pub_type: 杂志文章
doi:10.1089/end.1999.13.585
更新日期:1999-10-01 00:00:00
abstract:: Objective: To evaluate whether reducing the dose of fluoroscopy to ¼ of standard dose during unilateral ureteroscopy for ureteral stone treatment would impact in a reduction of total radiation emitted and whether this strategy would impact operation time, stone-free rate, ...
journal_title:Journal of endourology
pub_type: 杂志文章,随机对照试验
doi:10.1089/end.2018.0722
更新日期:2019-07-01 00:00:00
abstract:PURPOSE:To examine the incidence of urinary tract infection (UTI) after flexible cystoscopy (FC) and determine whether prophylactic norfloxacin reduces this incidence compared with placebo. PATIENTS AND METHODS:A double-blind trial was performed, randomizing 234 patients to either 400 mg of norfloxacin or placebo prio...
journal_title:Journal of endourology
pub_type: 杂志文章,随机对照试验
doi:10.1089/end.2005.19.1006
更新日期:2005-10-01 00:00:00
abstract::Water-Induced Thermotherapy (WIT trade mark ) was developed to treat lower urinary tract symptoms (LUTS) and to reduce bladder outlet obstruction (BOO) secondary to benign prostatic hyperplasia (BPH). The principle is to produce heat-induced coagulative necrosis and secondary ablation of the obstructing hyperplastic t...
journal_title:Journal of endourology
pub_type: 杂志文章,评审
doi:10.1089/089277903322518617
更新日期:2003-10-01 00:00:00
abstract:PURPOSE:To determine the effects of previous open nephrolithotomy on the results and morbidity of subsequent percutaneous nephrolithotomy (PCNL). PATIENTS AND METHODS:Between March 2005 and January 2006, 89 patients underwent PCNL at our institution. We compared the patients who had had previous open surgery on the sa...
journal_title:Journal of endourology
pub_type: 杂志文章
doi:10.1089/end.2006.0293
更新日期:2007-04-01 00:00:00
abstract:BACKGROUND AND OBJECTIVE:Repair of ureteral injuries and strictures often necessitates a major reconstructive procedure such as a psoas hitch, Boari flap, renal mobilization, ileal interposition, or autotransplantation. Tissue expanders have been used to elongate nerves and arteries. We examined the effects of acute ur...
journal_title:Journal of endourology
pub_type: 杂志文章
doi:10.1089/end.1999.13.245
更新日期:1999-05-01 00:00:00
abstract:BACKGROUND AND PURPOSE:The use of bipolar electrocautery has proven advantages over monopolar energy during transurethral surgery by limiting hyponatremia and its clinical sequelae. Percutaneous ablation of caliceal diverticula and parapelvic renal cysts has been shown to be an effective surgical approach for the manag...
journal_title:Journal of endourology
pub_type: 杂志文章
doi:10.1089/end.2010.0525
更新日期:2011-05-01 00:00:00
abstract::Because it is still a puzzling debate whether ligation of a unilateral varicose spermatic vein is worth performing by laparoscopy, even with the two-port technique, we conducted a study in which 280 patients with palpable left varicoceles were treated with spermatic vein ligation either by open surgery (120 patients) ...
journal_title:Journal of endourology
pub_type: 杂志文章
doi:10.1089/end.1996.10.435
更新日期:1996-10-01 00:00:00
abstract:PURPOSE:This study was designed to determine the outcome and safety of tubeless percutaneous nephrolithotomy (PCNL) in the treatment of renal calculi. PATIENTS AND METHODS:Between November 2005 and March 2006, 48 patients were randomized to either an 18F Re-entry nephrostomy tube (group 1) or a 6F Double-J stent (grou...
journal_title:Journal of endourology
pub_type: 杂志文章,随机对照试验
doi:10.1089/end.2006.0216
更新日期:2007-09-01 00:00:00
abstract:BACKGROUND AND PURPOSE:Holmium:YAG lithotripsy of uric acid calculi produces cyanide. The laser and stone parameters required to produce cyanide are poorly defined. In this study, we tested the hypotheses that cyanide production: (1) varies with holmium:YAG power settings; (2) varies among holmium:YAG, pulsed-dye, and ...
journal_title:Journal of endourology
pub_type: 杂志文章
doi:10.1089/end.2000.14.169
更新日期:2000-03-01 00:00:00
abstract::Minimal bleeding during endoscopic surgery of the urinary tract may prevent optimum vision. We used neurosurgical patties for dissection during our laparoscopic procedures in the pediatric population and aimed to describe this technique as an alternative to standard ways of dissection during laparoscopic procedures. W...
journal_title:Journal of endourology
pub_type: 杂志文章
doi:10.1089/end.2010.0435
更新日期:2011-05-01 00:00:00
abstract::Although the supracostal approach is thought to increase the difficulties and patient morbidity of PCNL, it facilitates the management of certain urinary infirmities, such as UPJ obstruction, staghorn stone, upper pole stone, proximal ureteral abnormalities, impacted UPJ stone and upper calix diverticulum. Hereby the ...
journal_title:Journal of endourology
pub_type: 杂志文章
doi:10.1089/end.2009.1531
更新日期:2009-10-01 00:00:00
abstract::The permanent Urolume Wallstent has been used for the relief of bladder outlet obstruction (BOO), detrusor-external sphincter dyssnergia (DESD), and recurrent bulbar urethral strictures. Because of its woven construction, it allows ingrowth of urothelial tissue, resulting in complete epithelialization by 6 to 12 month...
journal_title:Journal of endourology
pub_type: 临床试验,杂志文章,多中心研究
doi:10.1089/end.1997.11.477
更新日期:1997-12-01 00:00:00
abstract::The treatment results obtained in children using an unmodified Dornier HM3 or a Medstone STS lithotripter for renal and ureteral stones were compared. The Dornier HM3 was used to treat 28 renal and 10 ureteral stones, while the Medstone STS was used to treat 73 renal and 34 ureteral stones. The treatment results were ...
journal_title:Journal of endourology
pub_type: 杂志文章
doi:10.1089/end.1996.10.493
更新日期:1996-12-01 00:00:00
abstract:PURPOSE:We retrospectively investigated the factors that affect the success of rigid ureteroscopy in the pediatric population for the management of pediatric ureteral stones. PATIENTS AND METHODS:We present a retrospective review of 61 consecutive pediatric patients who underwent 66 rigid ureteroscopy procedures for u...
journal_title:Journal of endourology
pub_type: 杂志文章
doi:10.1089/end.2009.0476
更新日期:2010-08-01 00:00:00