Abstract:
BACKGROUND AND PURPOSE:Oxalobacter formigenes is an anaerobic commensal colonic bacterium capable of degrading oxalate through the enzyme oxalyl-CoA decarboxylase. It has been theorized that individuals who lack this bacterium have higher intestinal oxalate absorption, leading to a higher urinary oxalate concentration and an increased risk of calcium oxalate urolithiasis. We performed a prospective, controlled study to evaluate O. formigenes colonization in calcium oxalate stone formers and to correlate colonization with urinary oxalate and other standard urinary stone risk factors. PATIENTS AND METHODS:Thirty-five first-time calcium oxalate stone formers were compared with 10 control subjects having no history of urolithiasis and a normal renal ultrasound scan. All subjects underwent standard metabolic testing by submitting serum and 24-hour urine specimens. In addition, all subjects submitted stool samples for culture and detection of O. formigenes by Xentr(ix) O. formigenes Monitor. RESULTS:Intestinal Oxalobacter was detected in only 26% of the stone formers compared with 60% of the controls (p < 0.05). Overall, the average urinary oxalate excretion by the two groups was similar (38.6 mg/day v 40.8 mg/day). Among stone formers, however, there were statistically higher urinary oxalate concentrations in O. formigenes-negative patients compared with those testing positive (41.7 mg/day v 29.4 mg/day) (p = 0.03). Furthermore, all 10 stone formers with hyperoxaluria (>44 mg/day) tested negative for O. formigenes (p < 0.05). CONCLUSIONS:Calcium oxalate stone formers have a low rate of colonization with O. formigenes. Among stone formers, absence of intestinal Oxalobacter correlates with higher urinary oxalate concentration and an increased risk of hyperoxaluria. Introduction of the Oxalobacter bacterium or an analog of its enzyme oxalyl-CoA decarboxylase into the intestinal tract may be a treatment for calcium oxalate stone disease.
journal_name
J Endouroljournal_title
Journal of endourologyauthors
Troxel SA,Sidhu H,Kaul P,Low RKdoi
10.1089/089277903321618743subject
Has Abstractpub_date
2003-04-01 00:00:00pages
173-6issue
3eissn
0892-7790issn
1557-900Xjournal_volume
17pub_type
杂志文章abstract::The long-term effects of extracorporeal shockwave lithotripsy (SWL) on children treated for renal calculi are unclear. To study the effects on the immature animal, we evaluated 31 Wistar white rats that underwent right nephrectomy at 30 days of age. At 40 days of age they were divided into three groups: a control grou...
journal_title:Journal of endourology
pub_type: 杂志文章
doi:10.1089/end.1995.9.45
更新日期:1995-02-01 00:00:00
abstract:BACKGROUND AND PURPOSE:Although the evidence is sparse, most urologists advise the insertion of a safety guide wire (SGW) alongside the ureteroscope whenever performing ureteroscopy (URS). The aim of the study was to compare the results of ureteroscopic treatment for ureteral stones at the Oslo University Hospital (OUH...
journal_title:Journal of endourology
pub_type: 杂志文章
doi:10.1089/end.2013.0248
更新日期:2013-10-01 00:00:00
abstract:: Introduction: To compare short- and midterm outcomes of the first 55 patients undergoing robot-assisted kidney transplant (RAKT) with patients undergoing open kidney transplant (OKT) during the same period in a tertiary care hospital. Materials and...
journal_title:Journal of endourology
pub_type: 杂志文章
doi:10.1089/end.2020.0213
更新日期:2020-09-01 00:00:00
abstract::Urinary incontinence may be the result of various forms of detrusor overactivity. Several surgical therapies have been devised, but with the exception of procedures to relieve urethral obstruction, none abolishes the overactivity or restores normal micturition. In general, ablative neurosurgery is considered only in p...
journal_title:Journal of endourology
pub_type: 杂志文章,评审
doi:10.1089/end.1996.10.213
更新日期:1996-06-01 00:00:00
abstract:PURPOSE:The impact of drainage type after percutaneous nephrolithotomy (PCNL) on the health-related quality of life (HRQoL) has been rarely studied. We conducted a prospective randomized study to evaluate the differences in HRQoL among patients who received different drainage types. METHODS:A total of 90 patients who ...
journal_title:Journal of endourology
pub_type: 杂志文章,随机对照试验
doi:10.1089/end.2017.0444
更新日期:2017-11-01 00:00:00
abstract:OBJECTIVE:To evaluate current practice patterns in U.S. emergency departments (EDs) for the diagnosis, treatment, and counseling of patients with ureteral calculi. METHODS:Hospital-based ED physicians were invited by e-mail to participate in a Survey-Monkey survey. E-mails were delivered in March 2008 by Direct Medica...
journal_title:Journal of endourology
pub_type: 杂志文章
doi:10.1089/end.2008.0615
更新日期:2009-06-01 00:00:00
abstract:: Introduction and Objective: Single-use flexible ureteroscopes have the benefit of decreasing infection transmission, avoiding sterilization need, and no maintenance cost. Primary objective was to compare in vivo performance and surgical outcomes with two single-use uretero...
journal_title:Journal of endourology
pub_type: 杂志文章
doi:10.1089/end.2020.0409
更新日期:2021-01-21 00:00:00
abstract:BACKGROUND AND PURPOSE:As life expectancy continues to increase, we will be faced with the need to counsel older patients on the risks and benefits of undergoing surgery. It is clear that laparoscopic renal surgery has significant benefits over open renal surgery. However, contemporary data on whether these benefits ca...
journal_title:Journal of endourology
pub_type: 杂志文章
doi:10.1089/end.2007.9885
更新日期:2007-11-01 00:00:00
abstract:PURPOSE:To assess whether intravenous magnesium sulfate infusion affects analgesic requirements during monitored anesthesia care (MAC) for shockwave lithotripsy (SWL). PATIENTS AND METHODS:Fifty patients in ASA class I or II undergoing SWL with MAC were randomized into two groups. Induction of MAC was produced by bolu...
journal_title:Journal of endourology
pub_type: 杂志文章,随机对照试验
doi:10.1089/end.2006.0195
更新日期:2007-02-01 00:00:00
abstract:PURPOSE:To report the outcomes of patients with ureteroenteric strictures after ileal conduit urinary diversion that were managed with Resonance metallic ureteral stents. PATIENTS AND METHODS:Ten ureteroenteric strictures in patients with ileal conduits that were managed with metallic ureteral stenting were retrospect...
journal_title:Journal of endourology
pub_type: 杂志文章
doi:10.1089/end.2008.0454
更新日期:2009-07-01 00:00:00
abstract::In one-third of patients, prostate cancer (PCa) is monofocal. These patients can undergo focal high-intensity focused ultrasound (HIFU) therapy of the tumor without damage to surrounding structures and not compromising uro-oncologic safety. Robot-assisted HIFU coagulates the entire targeted volume within the prostate ...
journal_title:Journal of endourology
pub_type: 杂志文章
doi:10.1089/end.2009.0439
更新日期:2010-05-01 00:00:00
abstract::Since the advantages of using ureteral stents in conjunction with extracorporeal shock wave lithotripsy were first recognized, the growing demand for outpatient stone treatment has made stent use much more frequent. However, prophylactic stent placement must be judicious to maximize success and minimize associated mor...
journal_title:Journal of endourology
pub_type: 杂志文章,评审
doi:10.1089/end.1993.7.155
更新日期:1993-04-01 00:00:00
abstract:PURPOSE:This report describes a new animal model for research on the parameters of shockwave delivery and the mechanisms of shockwave action in SWL. MATERIALS AND METHODS:Female pigs (approximately 45 kg) were anesthetized for creation of an upper pole peripheral caliceal access. The tract was dilated with a 30F Nephr...
journal_title:Journal of endourology
pub_type: 杂志文章
doi:10.1089/089277902320913215
更新日期:2002-10-01 00:00:00
abstract::During cryotherapy of the prostate, identification of probe tips that are misplaced into the bladder is often not readily apparent via transrectal ultrasonography. Ultimately, cystoscopy is needed to ensure this has not occurred before initiating a freeze. We describe the innovative use of continuous flexible cystosco...
journal_title:Journal of endourology
pub_type: 杂志文章
doi:10.1089/end.2011.0417
更新日期:2012-04-01 00:00:00
abstract:BACKGROUND AND PURPOSE:Vascular control is an important step in laparoscopic nephrectomy. The various options are titanium clips, Hem-o-lok clips (Weck Closure Systems, Research Triangle Park, NC), T-knot, and stapling devices. We report our experience with the use of Hem-o-lok clips. PATIENTS AND METHODS:From January...
journal_title:Journal of endourology
pub_type: 杂志文章
doi:10.1089/end.2006.20.202
更新日期:2006-03-01 00:00:00
abstract:: Introduction: There has been a surge in robotic surgery research publications over the past 20 years. However, to date, there has been no characterization of urology's contribution to the robotic field, and there is a lack of bibliometric literature to guide future investi...
journal_title:Journal of endourology
pub_type: 杂志文章
doi:10.1089/end.2018.0866
更新日期:2019-05-01 00:00:00
abstract:PURPOSE:To define possible predictive factors for success and complications for ureteroscopic holmium laser lithotripsy procedures. PATIENTS AND METHODS:All 105 ureteroscopic holmium laser lithotripsy procedures performed between 1996 and 2005 were analyzed. Data recorded were sex, age, stone size, stone location, com...
journal_title:Journal of endourology
pub_type: 杂志文章
doi:10.1089/end.2007.0299
更新日期:2008-02-01 00:00:00
abstract:PURPOSE:The aim of this study was to assess the metabolic characteristics and risks of stone recurrence in young adult stone patients in Korea. PATIENTS AND METHODS:The medical records of 1532 patients presenting with renal or ureteric stones at our stone clinic between 1994 and 2015 were retrospectively reviewed. Pat...
journal_title:Journal of endourology
pub_type: 杂志文章
doi:10.1089/end.2017.0210
更新日期:2017-08-01 00:00:00
abstract:BACKGROUND AND PURPOSE:There have been several reports of rhabdomyolysis occurring after prolonged laparoscopic procedures in the flank position. Accordingly, we evaluated interface pressures between the skin and three commonly used operating room table surfaces. The aim of our study was to determine if pressure change...
journal_title:Journal of endourology
pub_type: 杂志文章
doi:10.1089/end.2008.0047
更新日期:2008-06-01 00:00:00
abstract:PURPOSE:We describe and evaluate a new transperineal laparoscopic approach for male patients, designed to facilitate laparoscopic prostatectomy and cystectomy. PATIENTS AND METHODS:We operated on 12 patients. We did three laparoscopic prostatectomies and nine laparoscopic cystectomies. On five, an ileal conduit was ma...
journal_title:Journal of endourology
pub_type: 杂志文章
doi:10.1089/end.2010.0247
更新日期:2011-04-01 00:00:00
abstract:OBJECTIVE:To evaluate the role of the fascial dilators modified with a scale marker in reducing fluoroscopy time during percutaneous nephrolithotomy (PCNL). METHOD:In a randomized clinical trial, eligible 100 consecutive patients anticipated to undergo single-tract PCNL were randomly assigned into two groups by the cl...
journal_title:Journal of endourology
pub_type: 杂志文章,随机对照试验
doi:10.1089/end.2012.0671
更新日期:2013-11-01 00:00:00
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journal_title:Journal of endourology
pub_type: 杂志文章
doi:10.1089/end.2016.0341
更新日期:2016-09-01 00:00:00
abstract::A new tip design of a 3.3F electrohydraulic probe for endoureteral lithotripsy was evaluated in comparison to a regular probe. The peak pressure, as well as the slope of the shock front, depend solely on the voltage. Increasing the capacity leads merely to broader pulses. A laser-like short high-pressure pulse has a g...
journal_title:Journal of endourology
pub_type: 杂志文章
doi:10.1089/end.1993.7.35
更新日期:1993-02-01 00:00:00
abstract:BACKGROUND AND PURPOSE:As many as 96% of patients report some kind of discomfort/pain during transrectal ultrasonography (TRUS)-guided prostate biopsy, and when pain is severe, it may be necessary to decrease the planned number of biopsies or interrupt the procedure. Various modalities have been recommended to alleviat...
journal_title:Journal of endourology
pub_type: 杂志文章,随机对照试验
doi:10.1089/end.2006.20.525
更新日期:2006-07-01 00:00:00
abstract:OBJECTIVE:To evaluate perioperative morbidity and mortality rate, a 3-year recurrence-free survival, and cancer-specific mortality rate in patients older than 80 years undergoing robot-assisted radical cystectomy (RARC). MATERIALS AND METHODS:We retrospectively collected data of 155 consecutive patients who received R...
journal_title:Journal of endourology
pub_type: 杂志文章
doi:10.1089/end.2016.0050
更新日期:2016-07-01 00:00:00
abstract:PURPOSE:To investigate a new method and its effect on the procedure of dilating the ejaculatory duct and flushing the seminal vesicle with an F9 seminal vesicle scope in patients with chronic and recurrent seminal vesiculitis. PATIENTS AND METHODS:Twenty-six patients with a diagnosis based to signs, laboratory detecti...
journal_title:Journal of endourology
pub_type: 临床试验,杂志文章
doi:10.1089/end.2010.0456
更新日期:2011-11-01 00:00:00
abstract:BACKGROUND AND PURPOSE:Caliceal diverticula are rare congenital abnormalities that can become symptomatic if associated with a calculus or infection. We review percutaneous management of caliceal diverticula. METHODS:Pathogenesis, clinical evaluation, management options, and recommended follow-up for symptomatic calic...
journal_title:Journal of endourology
pub_type: 杂志文章
doi:10.1089/end.2009.1541
更新日期:2009-10-01 00:00:00
abstract:PURPOSE:The CyberKnife (CK), a linear accelerator mounted on a robotic device, enables excellent dose conformation to the target and minimizes dose to surrounding normal tissue. It is a very suitable device for performing hypofractionated stereotactic body radiotherapy as monotherapy for low- to intermediate-risk prost...
journal_title:Journal of endourology
pub_type: 杂志文章
doi:10.1089/end.2009.0438
更新日期:2010-05-01 00:00:00
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journal_title:Journal of endourology
pub_type: 杂志文章
doi:10.1089/end.2000.14.401
更新日期:2000-06-01 00:00:00
abstract:BACKGROUND AND PURPOSE:A unilateral paravertebral (PVB) block with catheter can provide extendable analgesia without physiological changes. The objective of this study was to assess the efficacy of PVB bupivacaine for providing perioperative pain relief in adults undergoing percutaneous nephrolithotomy (PCNL) under gen...
journal_title:Journal of endourology
pub_type: 杂志文章,随机对照试验
doi:10.1089/end.2014.0179
更新日期:2014-09-01 00:00:00