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Temporary vena cava filters and ultrahigh streptokinase thrombolysis therapy: a clinical study.

Abstract：

PURPOSE:To assess the efficacy of temporary vena cava filters in patients undergoing ultrahigh-dose streptokinase thrombolysis for iliocaval thrombosis and to determine therapy success and filter and therapy complications. METHODS:Forty-five patients were studied regarding extension and characteristics of thrombosis, duration, success, and complications of thrombolysis therapy, filter type, access route, pulmonary embolisms, and filter complications. RESULTS:Complete recanalization was achieved in 57% of cases. Filters were inserted predominantly via a transbrachial route. One fatal pulmonary embolism (2%) occurred 1 day after starting thrombolysis. No other pulmonary embolism was noted. Other complications were induced by thrombolysis alone (n = 12), thrombolysis and filter (n = 9), and filter alone (n = 11). CONCLUSION:Fatal pulmonary embolisms as a complication of ultrahigh-dose treatment of pelvic or caval thrombosis can not safely be prevented by the temporary vena cava filters currently available. Filter design needs to be improved.

journal_name

Cardiovasc Intervent Radiol

journal_title

Cardiovascular and interventional radiology

authors

Lorch H,Zwaan M,Siemens HJ,Wagner T,Kagel C,Weiss HD

doi

10.1007/s002700010068

subject

Has Abstract

pub_date

2000-07-01 00:00:00

pages

273-8

issue

4

eissn

0174-1551

issn

1432-086X

pii

10.1007/s002700010068

journal_volume

23

pub_type

杂志文章

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