Human leukocyte antigen (HLA) phenotypes in siblings with osteosarcoma.

Abstract:

:Osteosarcoma was detected in two siblings. Their human leukocyte antigen (HLA) phenotypes were completely identical, although they were different from those of osteosarcoma patients in previous reports. Despite an extensive search of family and past history, no significant background related to the induction of cancer could be found. These cases suggest that genetic similarity may influence the development of osteosarcoma. Ascertainment of the HLA phenotypes in siblings with osteosarcoma might be a useful strategy to facilitate the early diagnosis of this tumor.

authors

Shinozaki T,Watanabe H,Shimizu T,Yanagawa T,Takagishi K

doi

10.1007/s004020050479

subject

Has Abstract

pub_date

2000-01-01 00:00:00

pages

343-5

issue

5-6

eissn

0936-8051

issn

1434-3916

journal_volume

120

pub_type

杂志文章
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